Immunocytochemical localization of claudin-1 in the maturation ameloblasts of rat incisors.

Abstract:

:Claudin-1 is a tight junction transmembrane protein. Its localization in the maturation ameloblasts of rat incisors was examined by immunofluorescence microscopy. Distal junction area of ruffle-ended ameloblasts (RA) and the Golgi apparatus of a sub-population of smooth-ended ameloblasts (SA) and RAs stained positive with anti-claudin-1 antibodies. Since it has been shown that ameloblasts repeatedly alternate between an SA and an RA morphology during enamel maturation, the presence of claudin-1 in the Golgi cisterns may indicate the presence of tight junction precursors before transportation to the junctional area.

journal_name

Front Physiol

journal_title

Frontiers in physiology

authors

Nishikawa S,Abe M

doi

10.3389/fphys.2010.00150

subject

Has Abstract

pub_date

2010-11-16 00:00:00

pages

150

issn

1664-042X

journal_volume

1

pub_type

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