Aging Increases Compensatory Saccade Amplitude in the Video Head Impulse Test.

abstract：:Background: Neuronal intranuclear inclusion disease (NIID) is a rare neurodegenerative disease. The clinical manifestations of NIID are complex and easily misdiagnosed. Based on the current knowledge of this disease, it is usually chronic, with almost no acute cases. Stroke-like disease is an extremely rare type of NI...

journal_title：Frontiers in neurology

authors： Lin P,Jin H,Yi KC,He XS,Lin SF,Wu G,Zhang ZQ

更新日期：2020-06-10 00:00:00

abstract：:Surface electromyography (sEMG) is a non-invasive method, which may be used in France by health practitioners without medical degree, such as physiotherapists, who are taught in Institutes of physiotherapy. However, very few hours are devoted to sEMG teaching in physiotherapist educational programs, especially in a fo...

journal_title：Frontiers in neurology

authors： Portero P,Dogadov AA,Servière C,Quaine F

更新日期：2020-12-03 00:00:00

abstract：:Temporal discrimination is the ability to determine that two sequential sensory stimuli are separated in time. For any individual, the temporal discrimination threshold (TDT) is the minimum interval at which paired sequential stimuli are perceived as being asynchronous; this can be assessed, with high test-retest and ...

journal_title：Frontiers in neurology

authors： Conte A,McGovern EM,Narasimham S,Beck R,Killian O,O'Riordan S,Reilly RB,Hutchinson M

更新日期：2017-11-28 00:00:00

abstract：:Objectives: To identify and compare the cerebrospinal fluid (CSF) parameters that predict the presence of neonatal bacterial meningitis using optimal cutoff values, and to derive and compare predictive profiles based on a combination of individual parameters for the same purpose. Study Design: The retrospective compon...

journal_title：Frontiers in neurology

authors： Huang H,Tan J,Gong X,Li J,Wang L,Xu M,Zhang X,Zhang Y,Huang L

更新日期：2019-01-23 00:00:00

abstract：:Background: While acute stress and pain are part of our inherent survival mechanisms, persistent stress and pain can negatively impact health and well-being. This may also lead to poor sleep and thus a lack of recovery. This study investigated the influence of stress and musculoskeletal pain on sleep quality. Methods:...

journal_title：Frontiers in neurology

authors： Vinstrup J,Jakobsen MD,Calatayud J,Jay K,Andersen LL

更新日期：2018-11-21 00:00:00

abstract：:Patient registries offer a powerful and practical means of real-world data collection system for rare diseases. Many guidelines have been released to standardize patient registries, although most of them do not address issues specific to rare disease patient registries. In November 2018, the European Medicines Agency ...

journal_title：Frontiers in neurology

authors： Marques R,Thole H,Ruiz de Morales JG

更新日期：2020-05-15 00:00:00

abstract：:This study aims to quantify passive muscle stiffness of spastic wrist flexors in stroke survivors using shear wave elastography (SWE) and to correlate with neural and non-neural contributors estimated from a biomechanical model to hyper-resistance measured during passive wrist extension. Fifteen hemiplegic individuals...

journal_title：Frontiers in neurology

authors： Leng Y,Wang Z,Bian R,Lo WLA,Xie X,Wang R,Huang D,Li L

更新日期：2019-07-10 00:00:00

abstract：:Background and Purpose: Patients with large vessel occlusion stroke (LVOS) need to be rapidly identified and transferred to comprehensive stroke centers (CSC). However, previous pre-hospital strategy remains challenging. We aimed to develop a modified scale to better predict LVOS. Methods: We retrospectively reviewed ...

journal_title：Frontiers in neurology

authors： Gong X,Chen Z,Shi F,Zhang M,Xu C,Zhang R,Lou M

更新日期：2019-04-17 00:00:00

abstract：:Background: Interhospital transfer for endovascular treatment (EVT) within neurovascular networks might result in transfer of patients who will not undergo EVT (futile transfer). Limited evidence exists on factors associated with the primary patient selection for interhospital transfer from primary stroke centers (PSC...

journal_title：Frontiers in neurology

authors： Stefanou MI,Stadler V,Baku D,Hennersdorf F,Ernemann U,Ziemann U,Poli S,Mengel A

更新日期：2020-12-04 00:00:00

abstract：INTRODUCTION:Core cerebrospinal fluid (CSF) biomarkers - Aβ42, Tau, and phosphorylated Tau (pTau) - have been recently incorporated in the revised criteria for Alzheimer's disease (AD). However, their widespread clinical application lacks standardization. Pre-analytical sample handling and storage play an important rol...

journal_title：Frontiers in neurology

authors： Leitão MJ,Baldeiras I,Herukka SK,Pikkarainen M,Leinonen V,Simonsen AH,Perret-Liaudet A,Fourier A,Quadrio I,Veiga PM,de Oliveira CR

更新日期：2015-07-08 00:00:00

abstract：:GNE myopathy is characterized by distal muscle weakness, and caused by recessive mutations in GNE. Its onset is characteristically in young adulthood, although a broad spectrum of onset age is known to exist. A large number of mutations in GNE are pathogenic and this clinical phenotype can be difficult to differentiat...

journal_title：Frontiers in neurology

authors： Soule T,Phan C,White C,Resch L,Lacson A,Martens K,Pfeffer G

更新日期：2018-11-08 00:00:00

abstract：:Background: This study's aim was to investigate a large cohort of dystonia patients for pathogenic and rare variants in the ATM gene, making use of a new, cost-efficient enrichment technology for NGS-based screening. Methods: Single molecule Molecular Inversion Probes (smMIPs) were used for targeted enrichment and seq...

journal_title：Frontiers in neurology

authors： Pogoda M,Hilke FJ,Lohmann E,Sturm M,Lenz F,Matthes J,Muyas F,Ossowski S,Hoischen A,Faust U,Sepahi I,Casadei N,Poths S,Riess O,Schroeder C,Grundmann K

更新日期：2019-12-18 00:00:00

abstract：:Background: In early multiple sclerosis (MS), thalamus atrophy and decreased integrity of the thalamocortical white matter (WM) tracts have been observed. Objective: To investigate the temporal association between thalamus volume and WM damage in the thalamocortical tract in subjects with early MS. Methods: At two tim...

journal_title：Frontiers in neurology

authors： Weeda MM,Pruis IJ,Westerveld ASR,Brouwer I,Bellenberg B,Barkhof F,Vrenken H,Lukas C,Schneider R,Pouwels PJW

更新日期：2020-11-17 00:00:00

abstract：:Children and adolescent athletes are at a higher risk for concussion than adults, and also experience longer recovery times and increased associated symptoms. It has also recently been demonstrated that multiple, seemingly mild concussions may result in exacerbated and prolonged neurological deficits. Objective assess...

journal_title：Frontiers in neurology

authors： Kiefer AW,Barber Foss K,Reches A,Gadd B,Gordon M,Rushford K,Laufer I,Weiss M,Myer GD

更新日期：2015-11-20 00:00:00

abstract：:Objective: Myotonia congenita (MC) is a rare muscle disease characterized by sarcolemma over-excitability inducing skeletal muscle stiffness. It can be inherited either as an autosomal dominant (Thomsen's disease) or an autosomal recessive (Becker's disease) trait. Both types are caused by loss-of-function mutations i...

journal_title：Frontiers in neurology

authors： Altamura C,Ivanova EA,Imbrici P,Conte E,Camerino GM,Dadali EL,Polyakov AV,Kurbatov SA,Girolamo F,Carratù MR,Desaphy JF

更新日期：2020-09-04 00:00:00

abstract：:Over the past decade, it was found that relatively simple sphingolipids, such as ceramide, sphingosine, sphingosine-1-phosphate, and glucosylceramide play important roles in neuronal functions by regulating rates of neuronal growth and differentiation. Homeostasis of membrane sphingolipids in neurons and myelin is ess...

journal_title：Frontiers in neurology

authors： Alessenko AV,Albi E

更新日期：2020-05-21 00:00:00

abstract：:Annual cycles of physiology and behavior are highly prevalent in organisms inhabiting temperate and polar regions. Examples in mammals include changes in appetite and body fat composition, hibernation and torpor, growth of antlers, pelage and horns, and seasonal reproduction. The timing of these seasonal cycles reflec...

journal_title：Frontiers in neurology

authors： Lewis JE,Ebling FJ

更新日期：2017-03-10 00:00:00

abstract：:Background: Patients with traumatic brain injury (TBI) exhibit a variable and unpredictable outcome. The proteins interleukin 10 (IL-10) and heart fatty acid-binding protein (H-FABP) have shown predictive values for the presence of intracranial lesions. Aim: To evaluate the individual and combined outcome prediction a...

journal_title：Frontiers in neurology

authors： Lagerstedt L,Azurmendi L,Tenovuo O,Katila AJ,Takala RSK,Blennow K,Newcombe VFJ,Maanpää HR,Tallus J,Hossain I,van Gils M,Menon DK,Hutchinson PJ,Zetterberg H,Posti JP,Sanchez JC

更新日期：2020-06-02 00:00:00

abstract：:SARS-CoV-2 is a highly pathogenic coronavirus that has caused an ongoing worldwide pandemic. Emerging in Wuhan, China in December 2019, the virus has spread rapidly around the world. Corona virus disease 2019 (COVID-19), which is caused by SARS-CoV-2, has resulted in significant morbidity and mortality. The most promi...

journal_title：Frontiers in neurology

authors： Khateb M,Bosak N,Muqary M

更新日期：2020-06-23 00:00:00

abstract：BACKGROUND:An estimated 30-50% of essential tremor (ET) diagnoses are incorrect, and the true diagnosis in those patients is often Parkinson's disease (PD) or other tremor disorders. There are general statements about the tremor in these ET and PD, but published data on the more subtle characteristics of tremor are sur...

journal_title：Frontiers in neurology

authors： Sternberg EJ,Alcalay RN,Levy OA,Louis ED

更新日期：2013-05-10 00:00:00

abstract：:The measurement of optic nerve sheath diameter (ONSD) has been reported as a non-invasive marker for intracranial pressure (ICP). Nevertheless, it is uncertain whether possible ONSD differences occur with age and sex in healthy and brain-injured populations. The aim of this study was to investigate the effects of sex ...

journal_title：Frontiers in neurology

authors： Cardim D,Czosnyka M,Chandrapatham K,Badenes R,Bertuccio A,Noto AD,Donnelly J,Pelosi P,Ball L,Hutchinson PJ,Robba C

更新日期：2020-08-07 00:00:00

abstract：:Ischemic stroke is one of the leading causes for death and disability worldwide. In patients with large space-occupying infarction, the subsequent edema complicated by transtentorial herniation poses a lethal threat. Especially in patients with malignant middle cerebral artery infarction, brain swelling secondary to t...

journal_title：Frontiers in neurology

authors： Pallesen LP,Barlinn K,Puetz V

更新日期：2019-01-09 00:00:00

abstract：:This study was undertaken to demonstrate the vascular protection of exogenous and endogenous hydrogen sulfide (H2S) on cerebral ischemia/reperfusion (I/R) injury. The effect of H2S on cerebrovascular dysfunction in middle cerebral artery (MCA) and neuronal damage were measured after cerebral I/R induced by transient m...

journal_title：Frontiers in neurology

authors： Wen JY,Wang M,Li YN,Jiang HH,Sun XJ,Chen ZW

更新日期：2018-10-19 00:00:00

abstract：:Study Objectives: To clarify the effects of sleep duration on stroke and stroke subtypes, we adopted a Mendelian randomization (MR) approach to evaluate their causal relationship. Methods: A genome-wide association study including 446,118 participants from UK biobank was used to identify instruments for short sleep, l...

journal_title：Frontiers in neurology

authors： Lu H,Wu PF,Li RZ,Zhang W,Huang GX

更新日期：2020-10-07 00:00:00

abstract：:Objective: The platelet-to-lymphocyte ratio (PLR) is a new marker of atherosclerotic inflammation and has been identified as a predictive factor in cardiovascular diseases, but its significance in patients with acute ischaemic stroke (AIS) who have undergone intravenous thrombolysis (IVT) is still unknown. Methods: Co...

journal_title：Frontiers in neurology

authors： Xu JH,He XW,Li Q,Liu JR,Zhuang MT,Huang FF,Bao GS

更新日期：2019-11-13 00:00:00

abstract：:Perinatal hypoxic-ischemic encephalopathy (HIE) can lead to neurodevelopmental disorders, including cerebral palsy. Standard care for neonatal HIE includes therapeutic hypothermia, which provides partial neuroprotection; magnetic resonance imaging (MRI) is often used to assess injury and predict outcome after HIE. Imm...

journal_title：Frontiers in neurology

authors： Doman SE,Girish A,Nemeth CL,Drummond GT,Carr P,Garcia MS,Johnston MV,Kannan S,Fatemi A,Zhang J,Wilson MA

更新日期：2018-05-08 00:00:00

abstract：:Objectives: This study aimed to assess the efficacy of minocycline for the treatment of acute ischemic stroke. Background: While there have been meta-analysis that surveyed the efficacy of minocycline in the treatment of acute stroke, they have some methodological limitations. We performed a new systematic review whic...

journal_title：Frontiers in neurology

authors： Sheng Z,Liu Y,Li H,Zheng W,Xia B,Zhang X,Yong VW,Xue M

更新日期：2018-12-20 00:00:00

abstract：BACKGROUND:Unlike many other central nervous system (CNS) tumors, the surgical management of primary central nervous system lymphomas (PCNSL) is traditionally limited by diagnostic biopsy. Studies that predate the use of modern neurosurgical techniques have reported a prohibitive operative morbidity for this surgery. T...

journal_title：Frontiers in neurology

authors： Yun J,Yang J,Cloney M,Mehta A,Singh S,Iwamoto FM,Neugut AI,Sonabend AM

更新日期：2017-09-12 00:00:00

abstract：:Background: The leading cause of death in China is stroke, a condition that also contributes heavily to the disease burden. Nontraumatic intracerebral hemorrhage (ICH) is the second most common cause of stroke. Compared to Western countries, in China the proportion of ICH is significantly higher. Standardized treatmen...

journal_title：Frontiers in neurology

authors： Li D,Sun H,Ru X,Sun D,Guo X,Jiang B,Luo Y,Tao L,Fu J,Wang W

更新日期：2018-12-11 00:00:00

abstract：:Major advances in neonatal care have led to significant improvements in survival rates for preterm infants, but this occurs at a cost, with a strong causal link between preterm birth and neurological deficits, including cerebral palsy (CP). Indeed, in high-income countries, up to 50% of children with CP were born pret...

journal_title：Frontiers in neurology

authors： Li J,McDonald CA,Fahey MC,Jenkin G,Miller SL

更新日期：2014-10-09 00:00:00