Vascular Protection of Hydrogen Sulfide on Cerebral Ischemia/Reperfusion Injury in Rats.

abstract：:Traumatic brain injury (TBI) is a major health concern worldwide. Laboratory studies utilizing animal models of TBI are essential for addressing pathological mechanisms of brain injury and development of innovative treatments. Over the past 75 years, pioneering head injury researchers have devised and tested a number ...

journal_title：Frontiers in neurology

authors： Lyeth BG

更新日期：2016-12-02 00:00:00

abstract：:Background: Ischemic cerebral infarction is a severe clinical condition that can cause serious mortality. Artesunate, an anti-malarial drug that is widely used in cancer treatment, is known to facilitate accelerated cell apoptosis. The aim of this study is to explore the possible neuroprotective effects of artesunate ...

journal_title：Frontiers in neurology

authors： Shao M,Shen Y,Sun H,Meng D,Huo W,Qi X

更新日期：2018-08-17 00:00:00

abstract：:Background: Chronic subdural hematoma (cSDH) is a debilitating condition with a high rate of recurrence after surgical evacuation. Summary: This review is focused on middle meningeal artery (MMA) embolization to treat cSDH. We discuss the underlying pathophysiology of chronic subdural hematoma and how cessation of art...

journal_title：Frontiers in neurology

authors： Moshayedi P,Liebeskind DS

更新日期：2020-08-27 00:00:00

abstract：:Amyotrophic lateral sclerosis (ALS) is a late-onset neurodegenerative condition, most widely characterized by the selective vulnerability of motor neurons and the poor life expectancy of afflicted patients. Limited disease-modifying therapies currently exist, which only further attests to the substantial heterogeneity...

journal_title：Frontiers in neurology

authors： Gaur N,Perner C,Witte OW,Grosskreutz J

更新日期：2020-05-27 00:00:00

abstract：:Huntington disease (HD) is caused by an abnormally expanded cytosine-adenine-guanine (CAG) trinucleotide repeat in the HTT gene. Age and CAG-expansion number are related to age at diagnosis and can be used to index disease progression. However, observed onset-age variability suggests that other factors also modulate p...

journal_title：Frontiers in neurology

authors： Ciarochi JA,Calhoun VD,Lourens S,Long JD,Johnson HJ,Bockholt HJ,Liu J,Plis SM,Paulsen JS,Turner JA,PREDICT-HD Investigators and Coordinators of the Huntington Study Group.

更新日期：2016-09-21 00:00:00

abstract：:Background and objective: The trajectories of long-term and domain-specific cognitive alterations over a decade after stroke are largely unknown. This study aims to investigate the dynamic alterations of domain-specific cognitive performance among young stroke survivors over 10 years after their first stroke. Methods:...

journal_title：Frontiers in neurology

authors： Elgh E,Hu X

更新日期：2019-02-12 00:00:00

abstract：:[This corrects the article DOI: 10.3389/fneur.2018.01033.]. ...

journal_title：Frontiers in neurology

authors： VanElzakker MB,Brumfield SA,Lara Mejia PS

更新日期：2020-09-17 00:00:00

abstract：:Epilepsy may reflect a focal abnormality of cerebral tissue, but the generation of seizures typically involves propagation of abnormal activity through cerebral networks. We examined epileptiform discharges (spikes) with dense array electroencephalography (dEEG) in five patients to search for the possible engagement o...

journal_title：Frontiers in neurology

authors： Song J,Tucker DM,Gilbert T,Hou J,Mattson C,Luu P,Holmes MD

更新日期：2013-05-15 00:00:00

abstract：:Introduction: Cerebral autosomal dominant arteriopathy and subcortical infarct leukoencephalopathy (CADASIL) is the most common form of hereditary stroke caused by a mutation in the NOTCH3 gene located on the short arm of chromosome 19. A small number of published reports describe CADASIL patients who were initially d...

journal_title：Frontiers in neurology

authors： Khan A,Abedi V,Li J,Malik MT,Esch M,Zand R

更新日期：2020-09-04 00:00:00

abstract：:Purpose: Adults with cerebral palsy experience challenges related to lifelong disability, such as stress, fatigue, pain and emotional issues. E-health services can be delivered regardless of residence and level of functioning. The aim of this pilot study was to explore the potential benefits and feasibility of a mindf...

journal_title：Frontiers in neurology

authors： Høye H,Jahnsen RB,Løvstad M,Hartveit JF,Sørli H,Tornås S,Månum G

更新日期：2020-04-03 00:00:00

abstract：:Anticoagulation is highly effective in preventing stroke due to atrial fibrillation, but numerous studies have demonstrated low utilization of anticoagulation for these patients. Assessment of clinicians' attitudes on this topic indicate that fear of intracerebral hemorrhage (ICH), rather than appreciation of anticoag...

journal_title：Frontiers in neurology

authors： Fisher M

更新日期：2013-10-04 00:00:00

abstract：:Spinal muscular atrophy (SMA) is a severe neuromuscular disorder characterized by the degeneration of motor neurons in the spinal cord, and comprises a broad clinical spectrum. With the advent of new therapies (e.g., Nusinersen) for patients of all ages and disease stages, sensitive clinical measures are needed to det...

journal_title：Frontiers in neurology

authors： Kruse T,Lehmann HC,Braumann B,Fink GR,Wunderlich G

更新日期：2020-02-25 00:00:00

abstract：:Objective: To identify reproducible sub-classes of traumatic brain injury (TBI) that correlate with patient outcomes. Methods: Two TBI datasets from the Federal Interagency Traumatic Brain Injury Research (FITBIR) Informatics System were utilized, Transforming Research and Clinical Knowledge in Traumatic Brain Injury ...

journal_title：Frontiers in neurology

authors： Si B,Dumkrieger G,Wu T,Zafonte R,Dodick DW,Schwedt TJ,Li J

更新日期：2018-08-13 00:00:00

abstract：:Most blast-induced traumatic brain injuries (bTBI) are mild in severity and culpable for the lingering and persistent neuropsychological complaints in affected individuals. There is evidence that the prevalence of symptoms post-exposure may be sex-specific. Our laboratory has focused on changes in the monoamine and th...

journal_title：Frontiers in neurology

authors： Kawa L,Arborelius UP,Hökfelt T,Risling M

更新日期：2020-10-15 00:00:00

abstract：:Background: Better upper limb recovery after stroke could be achieved through tailoring rehabilitation interventions directly at movement deficits. Aim: To identify potential; targets for therapy by synthesizing findings of differences in kinematics and muscle activity between stroke survivors and healthy adults perfo...

journal_title：Frontiers in neurology

authors： Collins KC,Kennedy NC,Clark A,Pomeroy VM

更新日期：2018-06-25 00:00:00

abstract：:Background: Intracranial carotid artery calcification (ICAC) on computed tomography (CT) is a marker of atherosclerosis and an independent predictor of vascular events including stroke. While vitamin K antagonists (VKAs) are used to prevent embolic stroke, they have been shown to increase levels of both coronary and e...

journal_title：Frontiers in neurology

authors： Peeters MTJ,Houben R,Postma AA,van Oostenbrugge RJ,Schurgers LJ,Staals J

更新日期：2019-12-20 00:00:00

abstract：:Background and Purpose: Recent findings suggested that non-stenosing atherosclerosis (NSA) may play an important pathogenic role, especially in cryptogenic strokes. Furthermore, arterial stiffness has been suggested to be a useful tool in identifying patients with embolic stroke of undetermined source (ESUS) with poor...

journal_title：Frontiers in neurology

authors： Acampa M,Lazzerini PE,Manfredi C,Guideri F,Tassi R,Domenichelli C,Cartocci A,Martini G

更新日期：2020-07-24 00:00:00

abstract：:Tau accumulation is a prominent feature in a variety of neurodegenerative disorders and remarkable effort has been expended working out the biochemistry and cell biology of this cytoplasmic protein. Tau's wayward properties may derive from germline mutations in the case of frontotemporal lobar degeneration (FTLD-MAPT)...

journal_title：Frontiers in neurology

authors： Kang SG,Eskandari-Sedighi G,Hromadkova L,Safar JG,Westaway D

更新日期：2020-11-12 00:00:00

abstract：INTRODUCTION:Options currently available to individuals with upper limb loss range from prosthetic hands that can perform many movements, but require more cognitive effort to control, to simpler terminal devices with limited functional abilities. We attempted to address this issue by designing a myoelectric control sys...

journal_title：Frontiers in neurology

authors： Gailey A,Artemiadis P,Santello M

更新日期：2017-02-01 00:00:00

abstract：:Aims: To examine trajectories of employment probability up to 10 years following moderate-to-severe traumatic brain injury (TBI) and identify significant predictors from baseline socio-demographic and injury characteristics. Methods: A longitudinal observational study followed 97 individuals with moderate-to-severe TB...

journal_title：Frontiers in neurology

authors： Howe EI,Andelic N,Perrin PB,Røe C,Sigurdardottir S,Arango-Lasprilla JC,Lu J,Løvstad M,Forslund MV

更新日期：2018-12-05 00:00:00

abstract：:Objectives: To report two novel DNA2 gene mutations causing early onset myopathy with cardiac involvement and late onset mitochondriopathy with rhabdomyolysis. Methods: We performed detailed clinical, muscle histopathology and molecular studies including mitochondrial gene NGS analysis in two patients (Patient 1 and 2...

journal_title：Frontiers in neurology

authors： González-Del Angel A,Bisciglia M,Vargas-Cañas S,Fernandez-Valverde F,Kazakova E,Escobar RE,Romero NB,Jardel C,Rucheton B,Stojkovic T,Malfatti E

更新日期：2019-10-04 00:00:00

abstract：:Gait disturbances are one of the principal and most incapacitating symptoms of Parkinson's disease (PD). In addition, walking economy is impaired in PD patients and could contribute to excess fatigue in this population. An important number of studies have shown that treadmill training can improve kinematic parameters ...

journal_title：Frontiers in neurology

authors： Fernández-Del-Olmo MA,Sanchez JA,Bello O,Lopez-Alonso V,Márquez G,Morenilla L,Castro X,Giraldez M,Santos-García D

更新日期：2014-09-26 00:00:00

abstract：:Although orthodontic treatment is common, orthodontic force often induced pain. Low-level laser therapy (LLLT) has been investigated to improve therapeutic comfort. In dentistry, LLLT is mainly applied using two types of lasers, CO2 and diode lasers, whose biological actions are thought to be associated with wavelengt...

journal_title：Frontiers in neurology

authors： Tsuchiya T,Hasegawa N,Yugawa M,Sasaki A,Suda N,Adachi K

更新日期：2020-06-05 00:00:00

abstract：:The evidence demonstrating the benefits of exercise is indisputable for healthy subjects, and more recently, it is growing for Parkinson's disease (PD) patients. Due to its easy access, low cost, social facilitation and, above all, the symptomatic effect, clinical exercise may have a profound impact on PD management. ...

journal_title：Frontiers in neurology

authors： Bouça-Machado R,Venturelli M,Tinazzi M,Schena F,Ferreira JJ

更新日期：2020-04-02 00:00:00

abstract：:Background and Purpose: Accurate prediction of functional outcomes after stroke would provide evidence for reasonable poststroke management. This study aimed to develop and validate a nomogram for individualized prediction of 1-year unfavorable outcomes in Chinese acute ischemic stroke (AIS) patients. Methods: We gath...

journal_title：Frontiers in neurology

authors： Li X,Wang F,Zhao Z,Sun C,Liao J,Li X,Huang C,Nyame L,Zhao Z,Zheng X,Zhou J,Li M,Zou J

更新日期：2020-06-30 00:00:00

abstract：:Objectives: To identify and compare the cerebrospinal fluid (CSF) parameters that predict the presence of neonatal bacterial meningitis using optimal cutoff values, and to derive and compare predictive profiles based on a combination of individual parameters for the same purpose. Study Design: The retrospective compon...

journal_title：Frontiers in neurology

authors： Huang H,Tan J,Gong X,Li J,Wang L,Xu M,Zhang X,Zhang Y,Huang L

更新日期：2019-01-23 00:00:00

abstract：:Aim: The aim of the study was to investigate the effect of the onset of Parkinson's disease (PD) on life satisfaction. Method: Data from 2008, 2011, and 2014 were used from a population-based prospective cohort (German Ageing Survey; 8,982 observations in FE regression analysis) of community-residing individuals in th...

journal_title：Frontiers in neurology

authors： Buczak-Stec EW,König HH,Hajek A

更新日期：2018-07-25 00:00:00

abstract：:Localization of the epileptogenic zone (EZ) is crucial in the surgical treatment of focal epilepsy. Recently, EEG studies have revealed that the EZ exhibits abnormal connectivity, which has led investigators to now consider connectivity as a biomarker to localize the EZ. Further, abnormal connectivity of the EZ may pr...

journal_title：Frontiers in neurology

authors： Gupta K,Grover P,Abel TJ

更新日期：2020-11-25 00:00:00

abstract：:Neurocysticercosis (NC) is the most common parasitic infection of the central nervous system (CNS). Several studies have reported an association between NC and mesial temporal lobe epilepsy (MTLE). We intended to evaluate the frequency of hippocampal atrophy (HA), clinical evolution and imaging findings in patients wi...

journal_title：Frontiers in neurology

authors： Jama-António JMC,Yasuda CL,Cendes F

更新日期：2019-04-30 00:00:00

abstract：:We present a case of a 43-year-old woman with a history of headaches and blurry vision. Ophthalmologic examination identified papilledema. MR imaging demonstrated a right parietal region mass with patchy areas of contrast enhancement and focal calcifications. Intraoperative examination and exploration revealed an extr...

journal_title：Frontiers in neurology

authors： Ballester LY,Dunbar E,Guha-Thakurta N,Henson JW,Chandler H,Watkins J,Fuller GN

更新日期：2018-08-27 00:00:00