Malaria eradication and elimination: views on how to translate a vision into reality.

abstract：BACKGROUND:Cognitive impairment is common in patients with cerebral small vessel disease, but is not well detected using common cognitive screening tests which have been primarily devised for cortical dementias. We developed the Brief Memory and Executive Test (BMET); a rapid screening measure sensitive to the impaired...

journal_title：BMC medicine

authors： Brookes RL,Hollocks MJ,Khan U,Morris RG,Markus HS

更新日期：2015-03-11 00:00:00

abstract：BACKGROUND:Comorbidity between depressive and anxiety disorders is common. A hypothesis of the network perspective on psychopathology is that comorbidity arises due to the interplay of symptoms shared by both disorders, with overlapping symptoms acting as so-called bridges, funneling symptom activation between symptom ...

journal_title：BMC medicine

authors： Groen RN,Ryan O,Wigman JTW,Riese H,Penninx BWJH,Giltay EJ,Wichers M,Hartman CA

更新日期：2020-09-29 00:00:00

abstract：BACKGROUND:The benefit-risk balance of vaccines is regularly debated by the public, but the utility of media monitoring for regulatory bodies is unclear. A media monitoring study was conducted at the European Medicines Agency (EMA) concerning human papillomavirus (HPV) vaccines during a European Union (EU) referral pro...

journal_title：BMC medicine

authors： Bahri P,Fogd J,Morales D,Kurz X,ADVANCE consortium.

更新日期：2017-05-02 00:00:00

abstract：BACKGROUND:We investigated interactions between genetically and autoimmune-mediated coagulopathies by inducing experimental antiphospholipid syndrome (eAPS) in mice carrying the factor V Leiden (FVL) mutation. METHODS:eAPS was induced in heterozygous and homozygous FVL transgenic mice (C57BL/6 background) by immunizat...

journal_title：BMC medicine

authors： Katzav A,Grigoriadis NC,Ebert T,Touloumi O,Blank M,Pick CG,Shoenfeld Y,Chapman J

更新日期：2013-04-04 00:00:00

abstract：:Breast cancer is the most common cause of cancer and cancer death worldwide. Although most patients present with localized breast cancer and may be rendered disease-free with local therapy, distant recurrence is common and is the primary cause of death from the disease. Adjuvant systemic therapies are effective in red...

journal_title：BMC medicine

authors： Anampa J,Makower D,Sparano JA

更新日期：2015-08-17 00:00:00

abstract：:There has been increasing interest in the role of malaria drugs in preventing malaria transmission from humans to mosquitoes, which would help augment malaria control and elimination strategies. Nevertheless, only one stage in the malaria parasite life cycle, the gametocyte, is infectious to mosquitoes. The Worldwide ...

journal_title：BMC medicine

authors： Karunajeewa HA,Mueller I

更新日期：2016-06-18 00:00:00

abstract：BACKGROUND:The rapidly increasing number of activity-induced musculoskeletal injuries among adolescents and young adults is currently a true public health burden. The objective of this study was to investigate whether a neuromuscular training programme with injury prevention counselling is effective in preventing acute...

journal_title：BMC medicine

authors： Parkkari J,Taanila H,Suni J,Mattila VM,Ohrankämmen O,Vuorinen P,Kannus P,Pihlajamäki H

更新日期：2011-04-11 00:00:00

abstract：BACKGROUND:Preterm birth, small size for gestational age (SGA) and large size for gestational age (LGA) at birth are major risk factors for neonatal and long-term morbidity and mortality. It is unclear which periods of pregnancy are optimal for ultrasound screening to identify fetuses at risk of preterm birth, SGA or L...

journal_title：BMC medicine

authors： Erkamp JS,Voerman E,Steegers EAP,Mulders AGMGJ,Reiss IKM,Duijts L,Jaddoe VWV,Gaillard R

更新日期：2020-04-07 00:00:00

abstract：BACKGROUND:Cognitive impairment is very common in late-life depression, principally affecting executive skills and information processing speed. The aim of the study was to examine the effect of antidepressant treatment on cognitive performances over a 10-year period. METHODS:The community-based cohort included 7381 p...

journal_title：BMC medicine

authors： Carrière I,Norton J,Farré A,Wyart M,Tzourio C,Noize P,Pérès K,Fourrier-Réglat A,Ritchie K,Ancelin ML

更新日期：2017-04-19 00:00:00

abstract：BACKGROUND:Adiposity is a strong risk factor for cancer incidence and mortality. However, most of the evidence available has focused on body mass index (BMI) as a marker of adiposity. There is limited evidence on relationships of cancer with other adiposity markers, and if these associations are linear or not. The aim ...

journal_title：BMC medicine

authors： Parra-Soto S,Cowley ES,Rezende LFM,Ferreccio C,Mathers JC,Pell JP,Ho FK,Celis-Morales C

更新日期：2021-01-11 00:00:00

abstract：BACKGROUND:Clinical pathways are tools used to guide evidence-based healthcare that have been implemented internationally since the 1980s. However, there is widespread lack of agreement on the impact of clinical pathways on hospital resources and patient outcomes. This can be partially attributed to the confusion for b...

journal_title：BMC medicine

authors： Kinsman L,Rotter T,James E,Snow P,Willis J

更新日期：2010-05-27 00:00:00

abstract：BACKGROUND:In 2015, the Zika virus spread from Brazil throughout the Americas, posing an unprecedented challenge to the public health community. During the epidemic, international public health officials lacked reliable predictions of the outbreak's expected geographic scale and prevalence of cases, and were therefore ...

journal_title：BMC medicine

authors： Akhtar M,Kraemer MUG,Gardner LM

更新日期：2019-09-02 00:00:00

abstract：BACKGROUND:The World Health Organization (WHO) called for global action towards the elimination of cervical cancer. One of the main strategies is to screen 70% of women at the age between 35 and 45 years and 90% of women managed appropriately by 2030. So far, approximately 85% of cervical cancers occur in low- and midd...

journal_title：BMC medicine

authors： Xue P,Ng MTA,Qiao Y

更新日期：2020-06-03 00:00:00

abstract：BACKGROUND:When an outbreak of a novel pathogen occurs, some of the most pressing questions from a public-health point of view relate to its transmissibility, and the probabilities of different clinical outcomes following infection, to allow an informed response. Estimates of these quantities are often based on househo...

journal_title：BMC medicine

authors： House T,Inglis N,Ross JV,Wilson F,Suleman S,Edeghere O,Smith G,Olowokure B,Keeling MJ

更新日期：2012-10-09 00:00:00

abstract：BACKGROUND:Pendred syndrome, a common autosomal-recessive disorder characterized by congenital deafness and goiter, is caused by mutations of SLC26A4, which codes for pendrin. We investigated the relationship between pendrin and deafness using mice that have (Slc26a4+/+) or lack a complete Slc26a4 gene (Slc26a4-/-). M...

journal_title：BMC medicine

authors： Wangemann P,Itza EM,Albrecht B,Wu T,Jabba SV,Maganti RJ,Lee JH,Everett LA,Wall SM,Royaux IE,Green ED,Marcus DC

更新日期：2004-08-20 00:00:00

abstract：BACKGROUND:Virtual histology intravascular ultrasound (VH-IVUS) imaging is an innovative tool for the morphological evaluation of coronary atherosclerosis. Evidence for the effects of statin therapy on VH-IVUS parameters have been inconclusive. Consequently, we performed a systematic review and meta-analysis to investi...

journal_title：BMC medicine

authors： Banach M,Serban C,Sahebkar A,Mikhailidis DP,Ursoniu S,Ray KK,Rysz J,Toth PP,Muntner P,Mosteoru S,García-García HM,Hovingh GK,Kastelein JJ,Serruys PW,Lipid and Blood Pressure Meta-analysis Collaboration (LBPMC) Group.

更新日期：2015-09-18 00:00:00

abstract：BACKGROUND:We conducted this analysis to determine i) which journals publish high-quality, clinically relevant studies in internal medicine, general/family practice, general practice nursing, and mental health; and ii) the proportion of clinically relevant articles in each journal. METHODS:We performed an analytic sur...

journal_title：BMC medicine

authors： McKibbon KA,Wilczynski NL,Haynes RB

更新日期：2004-09-06 00:00:00

abstract：:Migraine is a common, chronic disorder of the brain causing much disability, as well as personal, familial and societal impact. Several oral preventive agents are available in different countries for the prevention of migraine, but none have performed better than 50% improvement in 50% of patients in a clinical trial....

journal_title：BMC medicine

authors： Mitsikostas DD,Rapoport AM

更新日期：2015-11-10 00:00:00

abstract：BACKGROUND:Although vaccination has been proved to be a safe, efficacious, and cost-effective intervention, immunisation rates remain suboptimal in many European countries, resulting in poor control of many vaccine-preventable diseases. DISCUSSION:The Summit of Independent European Vaccination Experts focused on the p...

journal_title：BMC medicine

authors： Schmitt HJ,Booy R,Aston R,Van Damme P,Schumacher RF,Campins M,Rodrigo C,Heikkinen T,Weil-Olivier C,Finn A,Olcén P,Fedson D,Peltola H

更新日期：2007-05-29 00:00:00

abstract：BACKGROUND:International medical graduates working in the UK are more likely to be censured in relation to fitness to practise compared to home graduates. Performance on the General Medical Council's (GMC's) Professional and Linguistic Assessments Board (PLAB) tests and English fluency have previously been shown to pre...

journal_title：BMC medicine

authors： Tiffin PA,Paton LW,Mwandigha LM,McLachlan JC,Illing J

更新日期：2017-03-20 00:00:00

abstract：BACKGROUND:Monogenic diabetes (MgD) accounts for 1-2% of all diabetes cases. In adults, MgD is difficult to distinguish from common diabetes causes. We assessed the diagnosis rate and genetic spectrum of MgD using next-generation sequencing in patients with late adolescence/adult-onset diabetes referred for a clinical ...

journal_title：BMC medicine

authors： Donath X,Saint-Martin C,Dubois-Laforgue D,Rajasingham R,Mifsud F,Ciangura C,Timsit J,Bellanné-Chantelot C,Monogenic Diabetes Study Group of the Société Francophone du Diabète.

更新日期：2019-07-11 00:00:00

abstract：BACKGROUND:Managing hearing communication for residents living with hearing loss and dementia in long-term care settings is challenging. This paper explores how care can be effective in optimising hearing communication for residents living with dementia. We argue that the underlying notion of permission or authorisatio...

journal_title：BMC medicine

authors： Crosbie B,Ferguson M,Wong G,Walker DM,Vanhegan S,Dening T

更新日期：2019-03-04 00:00:00

abstract：BACKGROUND:The declining efficacy of dihydroartemisinin-piperaquine against Plasmodium falciparum in Cambodia, along with increasing numbers of recrudescent cases, suggests resistance to both artemisinin and piperaquine. Available in vitro piperaquine susceptibility assays do not correlate with treatment outcome. A nov...

journal_title：BMC medicine

authors： Duru V,Khim N,Leang R,Kim S,Domergue A,Kloeung N,Ke S,Chy S,Eam R,Khean C,Loch K,Ken M,Lek D,Beghain J,Ariey F,Guerin PJ,Huy R,Mercereau-Puijalon O,Witkowski B,Menard D

更新日期：2015-12-22 00:00:00

abstract：BACKGROUND:Guidelines recommend that clinicians should make brief opportunistic behavioural interventions to patients who are obese to increase the uptake of effective weight loss programmes. The objective was to assess the effect of this policy on socioeconomic equity. METHODS:One thousand eight hundred eighty-two co...

journal_title：BMC medicine

authors： Graham J,Tudor K,Jebb SA,Lewis A,Tearne S,Adab P,Begh R,Jolly K,Daley A,Farley A,Lycett D,Nickless A,Aveyard P

更新日期：2019-03-01 00:00:00

abstract：:The launch of the 5th version of the Diagnostic and Statistical Manual of Mental Disorders (DSM-5) has sparked a debate about the current approach to psychiatric classification. The most basic and enduring problem of the DSM is that its classifications are heterogeneous clinical descriptions rather than valid diagnose...

journal_title：BMC medicine

authors： Wardenaar KJ,de Jonge P

更新日期：2013-09-12 00:00:00

abstract：BACKGROUND:Antiretroviral therapy (ART) alters platelet reactivity, and as a consequence, patients living with HIV may be at an increased risk of cardiovascular disease (CVD). The current evidence on platelet activation levels in patients with HIV remains inconclusive. We therefore aimed to systematically synthesise ev...

journal_title：BMC medicine

authors： Nkambule BB,Mxinwa V,Mkandla Z,Mutize T,Mokgalaboni K,Nyambuya TM,Dludla PV

更新日期：2020-11-18 00:00:00

abstract：:The diagnosis of multidrug resistant tuberculosis (MDR-TB) in any individual is the beginning of a prolonged and difficult therapeutic journey. It also marks the moment from which to begin consideration of how to manage close contacts. Preventive therapy for drug-susceptible latent tuberculosis infection has been demo...

journal_title：BMC medicine

authors： Moore DA

更新日期：2016-04-01 00:00:00

abstract：BACKGROUND:We update a previous systematic review to inform new World Health Organization HIV self-testing (HIVST) recommendations. We compared the effects of HIVST to standard HIV testing services to understand which service delivery models are effective for key populations. METHODS:We did a systematic review of rand...

journal_title：BMC medicine

authors： Witzel TC,Eshun-Wilson I,Jamil MS,Tilouche N,Figueroa C,Johnson CC,Reid D,Baggaley R,Siegfried N,Burns FM,Rodger AJ,Weatherburn P

更新日期：2020-12-03 00:00:00

abstract：BACKGROUND:Castration-resistant prostate cancer (CRPC) is associated with wide variations in survival. Recent studies of whole blood mRNA expression-based biomarkers strongly predicted survival but the genes used in these biomarker models were non-overlapping and their relationship was unknown. We developed a biomarker...

journal_title：BMC medicine

authors： Wang L,Gong Y,Chippada-Venkata U,Heck MM,Retz M,Nawroth R,Galsky M,Tsao CK,Schadt E,de Bono J,Olmos D,Zhu J,Oh WK

更新日期：2015-08-21 00:00:00

abstract：BACKGROUND:Resistance and tolerance to Plasmodium falciparum can determine the progression of malaria disease. However, quantitative evidence of tolerance is still limited. We investigated variations in the adverse impact of P. falciparum infections among African pregnant women under different intensities of malaria tr...

journal_title：BMC medicine

authors： Ndam NT,Mbuba E,González R,Cisteró P,Kariuki S,Sevene E,Rupérez M,Fonseca AM,Vala A,Maculuve S,Jiménez A,Quintó L,Ouma P,Ramharter M,Aponte JJ,Nhacolo A,Massougbodji A,Briand V,Kremsner PG,Mombo-Ngoma G,Desai M,

更新日期：2017-07-17 00:00:00