Impact of statin therapy on coronary plaque composition: a systematic review and meta-analysis of virtual histology intravascular ultrasound studies.

abstract：:In this video Q&A, we talk to Associate Professor Felice Jacka about population health approaches to the primary prevention of mental disorders across the lifespan. These include addressing lifestyle factors, such as diet, smoking and physical activity. Latest strategies are being developed through epidemiological stu...

journal_title：BMC medicine

authors： Jacka FN

更新日期：2015-10-14 00:00:00

abstract：BACKGROUND:The NPC1 gene encodes a protein involved in intracellular lipid trafficking; its second endosomal loop (loop 2) is a receptor for filoviruses. A polymorphism (His215Arg) in NPC1 was associated with obesity in Europeans. Adaptations to diet and pathogens represented powerful selective forces; thus, we analyze...

journal_title：BMC medicine

authors： Al-Daghri NM,Cagliani R,Forni D,Alokail MS,Pozzoli U,Alkharfy KM,Sabico S,Clerici M,Sironi M

更新日期：2012-11-15 00:00:00

abstract：BACKGROUND:The United Nation's Sustainable Development Goals for 2030 include reducing premature mortality from non-communicable diseases (NCDs) by one third. To assess the feasibility of this goal in China, we projected premature mortality in 2030 of NCDs under different risk factor reduction scenarios. METHODS:We us...

journal_title：BMC medicine

authors： Li Y,Zeng X,Liu J,Liu Y,Liu S,Yin P,Qi J,Zhao Z,Yu S,Hu Y,He G,Lopez AD,Gao GF,Wang L,Zhou M

更新日期：2017-07-11 00:00:00

abstract：BACKGROUND:Current policies encourage healthcare institutions to acquire clinical information systems (CIS) so that captured data can be used for secondary purposes, including clinical process improvement. Such policies do not account for the extra work required to repurpose data for uses other than direct clinical car...

journal_title：BMC medicine

authors： Morrison C,Jones M,Jones R,Vuylsteke A

更新日期：2013-04-10 00:00:00

abstract：BACKGROUND:External validations and comparisons of prognostic models or scores are a prerequisite for their use in routine clinical care but are lacking in most medical fields including chronic obstructive pulmonary disease (COPD). Our aim was to externally validate and concurrently compare prognostic scores for 3-year...

journal_title：BMC medicine

authors： Guerra B,Haile SR,Lamprecht B,Ramírez AS,Martinez-Camblor P,Kaiser B,Alfageme I,Almagro P,Casanova C,Esteban-González C,Soler-Cataluña JJ,de-Torres JP,Miravitlles M,Celli BR,Marin JM,Ter Riet G,Sobradillo P,Lange P,Ga

更新日期：2018-03-02 00:00:00

abstract：BACKGROUND:Dystroglycanopathies are a group of inherited disorders characterized by vast clinical and genetic heterogeneity and caused by abnormal functioning of the ECM receptor dystroglycan (Dg). Remarkably, among many cases of diagnosed dystroglycanopathies, only a small fraction can be linked directly to mutations ...

journal_title：BMC medicine

authors： Yatsenko AS,Kucherenko MM,Xie Y,Aweida D,Urlaub H,Scheibe RJ,Cohen S,Shcherbata HR

更新日期：2020-01-21 00:00:00

abstract：:The original article [1] contained an error in the presentation of Figure 1; this error has now been rectified and Figure 1 is now presented correctly. ...

journal_title：BMC medicine

authors： Wesolowski A,Taylor AR,Chang HH,Verity R,Tessema S,Bailey JA,Alex Perkins T,Neafsey DE,Greenhouse B,Buckee CO

更新日期：2018-12-28 00:00:00

abstract：BACKGROUND:The United States Preventive Services Task Force (USPSTF) recommends screening adults for depression in primary care settings when staff-assisted depression management programs are available. This recommendation, however, is based on evidence from depression management programs conducted with patients alread...

journal_title：BMC medicine

authors： Thombs BD,Ziegelstein RC,Roseman M,Kloda LA,Ioannidis JP

更新日期：2014-01-28 00:00:00

abstract：BACKGROUND:Although a number of risk factors are known to predict mortality within the first years after myocardial infarction, little is known about interactions between risk factors, whereas these could contribute to accurate differentiation of patients with higher and lower risk for mortality. This study explored th...

journal_title：BMC medicine

authors： van Loo HM,van den Heuvel ER,Schoevers RA,Anselmino M,Carney RM,Denollet J,Doyle F,Freedland KE,Grace SL,Hosseini SH,Parakh K,Pilote L,Rafanelli C,Roest AM,Sato H,Steeds RP,Kessler RC,de Jonge P

更新日期：2014-12-17 00:00:00

abstract：BACKGROUND:The prognostic significance of tumor-associated macrophages (TAM) in adult classical Hodgkin lymphoma (cHL) remains controversial. Here, we report a meta-analysis of the association of CD68 and CD163 infiltration on the clinical outcome of adult cHL. METHODS:A comprehensive search to identify relevant artic...

journal_title：BMC medicine

authors： Guo B,Cen H,Tan X,Ke Q

更新日期：2016-10-17 00:00:00

abstract：BACKGROUND:Brazil's Estratégia Saúde da Família (ESF) is one of the largest and most robustly evaluated primary healthcare programmes of the world, but it could be affected by fiscal austerity measures and by the possible end of the Mais Médicos programme (MMP)-a major intervention to increase primary care doctors in u...

journal_title：BMC medicine

authors： Rasella D,Hone T,de Souza LE,Tasca R,Basu S,Millett C

更新日期：2019-04-26 00:00:00

abstract：BACKGROUND:It has been presumed that Chlamydia trachomatis is transmitted between men only through anal or oral sex, but no mathematical models have tested this presumption. METHODS:To test this presumption, we created 20 compartmental mathematical models of different sexual practices that included both oral and anal ...

journal_title：BMC medicine

authors： Xu X,Chow EPF,Ong JJ,Hoebe CJPA,Zou Z,Hocking JS,Fairley CK,Zhang L

更新日期：2020-11-17 00:00:00

abstract：BACKGROUND:Obesity is common in young women, increasing insulin resistance (IR) and worsening pregnancy complications, including gestational diabetes (GDM). Women with polycystic ovary syndrome (PCOS) are commonly obese, which aggravates the severity of PCOS clinical expression. Relationships between these common insul...

journal_title：BMC medicine

authors： Kakoly NS,Earnest A,Moran LJ,Teede HJ,Joham AE

更新日期：2017-11-06 00:00:00

abstract：BACKGROUND:The focus of this study is to identify particular microRNA (miRNA) signatures in exosomes derived from plasma of 435 human epidermal growth factor receptor 2 (HER2)-positive and triple-negative (TN) subtypes of breast cancer (BC). METHODS:First, miRNA expression profiles were determined in exosomes derived ...

journal_title：BMC medicine

authors： Stevic I,Müller V,Weber K,Fasching PA,Karn T,Marmé F,Schem C,Stickeler E,Denkert C,van Mackelenbergh M,Salat C,Schneeweiss A,Pantel K,Loibl S,Untch M,Schwarzenbach H

更新日期：2018-10-10 00:00:00

abstract：BACKGROUND:It is a common practice to use a singleton fetal growth standard to assess twin growth. We aim to create a twin fetal weight standard which is also adjustable for race/ethnicity and other factors. METHODS:Over half a million twin births of low risk pregnancies in the US, from 1995 to 2004, were used to cons...

journal_title：BMC medicine

authors： Zhang J,Mikolajczyk R,Lei X,Sun L,Yu H,Cheng W

更新日期：2015-07-03 00:00:00

abstract：:This comment relates to articles published in archived content of the journal Head and Neck Oncology and is not related to the content of BMC Medicine in any way. ...

journal_title：BMC medicine

authors： BioMed Central.

更新日期：2014-02-05 00:00:00

abstract：BACKGROUND:Pregnancy and pregnancy loss may be linked to cardiovascular disease (CVD). However, the evidence is still inconsistent, especially in East Asians, whose reproductive patterns differ importantly from those in the West. We examined the associations of pregnancy, miscarriage, induced abortion, and stillbirth w...

journal_title：BMC medicine

authors： Peters SAE,Yang L,Guo Y,Chen Y,Bian Z,Tian X,Chang L,Zhang S,Liu J,Wang T,Chen J,Li L,Woodward M,Chen Z,China Kadoorie Biobank collaboration group.

更新日期：2017-08-08 00:00:00

abstract：BACKGROUND:Clinical decision support systems assist physicians in interpreting complex patient data. However, they typically operate on a per-patient basis and do not exploit the extensive latent medical knowledge in electronic health records (EHRs). The emergence of large EHR systems offers the opportunity to integrat...

journal_title：BMC medicine

authors： Gottlieb A,Stein GY,Ruppin E,Altman RB,Sharan R

更新日期：2013-09-02 00:00:00

abstract：BACKGROUND:Studies addressing the effects of aerobic exercise and a prudent diet on lipid and lipoprotein concentrations in adults have reached conflicting conclusions. The purpose of this study was to determine the effects of aerobic exercise combined with a prudent diet on lipid and lipoprotein concentrations in adul...

journal_title：BMC medicine

authors： Kelley GA,Kelley KS,Roberts S,Haskell W

更新日期：2011-06-15 00:00:00

abstract：BACKGROUND:Several accomplishments have been achieved in triple-negative breast cancer (TNBC) research over the last year. The phase III IMpassion130 trial comparing chemotherapy plus atezolizumab versus chemotherapy plus placebo brought breast cancer into the immunotherapy era. Nevertheless, despite encouraging result...

journal_title：BMC medicine

authors： Marra A,Viale G,Curigliano G

更新日期：2019-05-09 00:00:00

abstract：BACKGROUND:Vaccination has reduced the global incidence of measles to the lowest rates in history. However, local interruption of measles virus transmission requires sustained high levels of population immunity that can be challenging to achieve and maintain. The herd immunity threshold for measles is typically stipula...

journal_title：BMC medicine

authors： Funk S,Knapp JK,Lebo E,Reef SE,Dabbagh AJ,Kretsinger K,Jit M,Edmunds WJ,Strebel PM

更新日期：2019-09-25 00:00:00

abstract：BACKGROUND:A sizeable fraction of tuberculosis (TB) cases go undiagnosed. By analysing data from enhanced demographic, microbiological and geospatial surveillance of TB registrations, we aimed to identify modifiable predictors of inequitable access to diagnosis and care. METHODS:Governmental community health workers (...

journal_title：BMC medicine

authors： MacPherson P,Khundi M,Nliwasa M,Choko AT,Phiri VK,Webb EL,Dodd PJ,Cohen T,Harris R,Corbett EL

更新日期：2019-01-29 00:00:00

abstract：:In a climate of economic uncertainty, cost effectiveness analysis is a potentially important tool for making choices about health care interventions. Methods for such analyses are well established, but the results need to be interpreted carefully and are subject to bias. Making decisions based on results of cost-effec...

journal_title：BMC medicine

authors： Hill SR

更新日期：2012-02-01 00:00:00

abstract：:The diagnosis of multidrug resistant tuberculosis (MDR-TB) in any individual is the beginning of a prolonged and difficult therapeutic journey. It also marks the moment from which to begin consideration of how to manage close contacts. Preventive therapy for drug-susceptible latent tuberculosis infection has been demo...

journal_title：BMC medicine

authors： Moore DA

更新日期：2016-04-01 00:00:00

abstract：BACKGROUND:Childhood trauma increases the risk for adult obesity through multiple complex pathways, and the neural substrates are yet to be determined. METHODS:Participants from three population-based neuroimaging cohorts, including the IMAGEN cohort, the UK Biobank (UKB), and the Human Connectome Project (HCP), were ...

journal_title：BMC medicine

authors： Luo Q,Zhang L,Huang CC,Zheng Y,Kanen JW,Zhao Q,Yao Y,Quinlan EB,Jia T,Banaschewski T,Bokde ALW,Bromberg U,Büchel C,Flor H,Frouin V,Garavan H,Gowland P,Heinz A,Ittermann B,Martinot JL,Martinot MP,Nees F,Orfanos

更新日期：2020-10-15 00:00:00

abstract：BACKGROUND:Network meta-analyses using individual participant data (IPD-NMAs) have been increasingly used to compare the effects of multiple interventions. Although there have been many studies on statistical methods for IPD-NMAs, it is unclear whether there are statistical defects in published IPD-NMAs and whether the...

journal_title：BMC medicine

authors： Gao Y,Shi S,Li M,Luo X,Liu M,Yang K,Zhang J,Song F,Tian J

更新日期：2020-06-01 00:00:00

abstract：BACKGROUND:Human fetal adrenal glands are highly active and, with the placenta, regulate circulating progesterone, estrogen and corticosteroids in the fetus. At birth the adrenals are essential for neonate salt retention through secretion of aldosterone, while adequate glucocorticoids are required to prevent adrenal in...

journal_title：BMC medicine

authors： Johnston ZC,Bellingham M,Filis P,Soffientini U,Hough D,Bhattacharya S,Simard M,Hammond GL,King P,O'Shaughnessy PJ,Fowler PA

更新日期：2018-02-12 00:00:00

abstract：BACKGROUND:Mathematical and computational models for infectious diseases are increasingly used to support public-health decisions; however, their reliability is currently under debate. Real-time forecasts of epidemic spread using data-driven models have been hindered by the technical challenges posed by parameter estim...

journal_title：BMC medicine

authors： Tizzoni M,Bajardi P,Poletto C,Ramasco JJ,Balcan D,Gonçalves B,Perra N,Colizza V,Vespignani A

更新日期：2012-12-13 00:00:00

abstract：BACKGROUND:Abnormal BMI is associated with discouraging IVF outcomes in fresh autologous or oocyte donor cycles, whether or not such a relation also holds true for women undergoing frozen-thawed embryo transfer (FET) remains unknown. In addition, it remains unclear the detrimental effect of abnormal BMI on IVF outcomes...

journal_title：BMC medicine

authors： Zhang J,Liu H,Mao X,Chen Q,Fan Y,Xiao Y,Wang Y,Kuang Y

更新日期：2019-06-26 00:00:00

abstract：:The hypothalamic-pituitary-adrenal axis is activated in response to stress. One of the activated hypothalamic hormones is arginine vasopressin, a hormone involved in hemodynamics and osmoregulation. Copeptin, the C-terminal part of the arginine vasopressin precursor peptide, is a sensitive and stable surrogate marker ...

journal_title：BMC medicine

authors： Nickel CH,Bingisser R,Morgenthaler NG

更新日期：2012-01-20 00:00:00