MicroRNAs in skeletal muscle and their regulation with exercise, ageing, and disease.

abstract：:Ticks and tick-borne pathogens affect health and welfare of companion animals worldwide, and some human tick-borne diseases are associated with exposure to domestic animals. Vaccines are the most environmentally friendly alternative to acaracides for the control of tick infestations, and to reduce the risk for tick-bo...

journal_title：Frontiers in physiology

authors： Contreras M,Villar M,de la Fuente J

更新日期：2019-07-26 00:00:00

abstract：:Atherosclerosis is considered as a chronic disease of arterial wall, with a strong contribution of inflammation. Dendritic cells (DCs) play a crucial role in the initiation of proatherogenic inflammatory response. Mature DCs present self-antigens thereby supporting differentiation of naïve T cells to effector cells th...

journal_title：Frontiers in physiology

authors： Chistiakov DA,Sobenin IA,Orekhov AN,Bobryshev YV

更新日期：2014-05-27 00:00:00

abstract：:Muscle strain is one of the most frequent sports injuries, having the rectus femoris (RF) muscle as the reported preferred site of quadriceps muscle strain. The decrease muscle stiffness could be an effective RF muscle strain prevention. In recent studies, a high-intensity static stretching intervention decreased pass...

journal_title：Frontiers in physiology

authors： Nakamura M,Sato S,Murakami Y,Kiyono R,Yahata K,Sanuki F,Yoshida R,Fukaya T,Takeuchi K

更新日期：2021-01-13 00:00:00

abstract：:Odontoblast cells generated from human dental pulp stem/progenitor cells (hDPSCs) secrete reparative dentin in responds to an injury. Endogenous Wnt signaling is also activated during this process, and these Wnt-activated cells are responsible for the following repair response. R-spondin 2 (Rspo2) is a potent stem cel...

journal_title：Frontiers in physiology

authors： Gong Y,Yuan S,Sun J,Wang Y,Liu S,Guo R,Dong W,Li R

更新日期：2020-08-07 00:00:00

abstract：:Breast cancer is the most common type of cancer among women and despite recent advances in the medical field, there are still some inherent limitations in the currently used screening techniques. The radiological interpretation of screening X-ray mammograms often leads to over-diagnosis and, as a consequence, to unnec...

journal_title：Frontiers in physiology

authors： Gerasimova E,Audit B,Roux SG,Khalil A,Gileva O,Argoul F,Naimark O,Arneodo A

更新日期：2014-05-08 00:00:00

abstract：:This study aimed to investigate the influence of different exercise training modalities [(i) a concurrent training based on physical activity recommendation from the World Health Organization group (PAR group), (ii) a high intensity interval training group (HIIT group), and (iii) a high intensity interval training add...

journal_title：Frontiers in physiology

authors： Amaro-Gahete FJ,De-la-O A,Jurado-Fasoli L,Dote-Montero M,Gutiérrez Á,Ruiz JR,Castillo MJ

更新日期：2019-04-24 00:00:00

abstract：:Due to the important biological role of red blood cells (RBCs) in vertebrates, the analysis of reshaping and dynamics of RBCs motion is a critical issue in physiology and biomechanics. In this paper the behavior of RBCs within the immature capillary plexus during embryonic development of zebrafish has been analyzed. R...

journal_title：Frontiers in physiology

authors： Djukic TR,Karthik S,Saveljic I,Djonov V,Filipovic N

更新日期：2016-10-07 00:00:00

abstract：:Alpine skiing has been an Olympic event since the first Winter Games in 1936. Nowadays, skiers compete in four main events: slalom, giant slalom, super-G and downhill. Here, we present an update on the biomechanics of alpine ski racers and their equipment. The technical and tactical ability of today's world-class skie...

journal_title：Frontiers in physiology

authors： Supej M,Holmberg HC

更新日期：2019-02-20 00:00:00

abstract：:A sedentary lifestyle is associated with increased cardiovascular risk factors and reduced cardiac compliance when compared to a lifestyle that includes exercise training. Exercise training increases cardiac compliance in humans, but the mechanisms underlying this improvement are unknown. A major determinant of cardia...

journal_title：Frontiers in physiology

authors： Chung CS,Hiske MA,Chadha A,Mueller PJ

更新日期：2020-02-05 00:00:00

abstract：:Periventricular-intraventricular hemorrhages (PIVH) and (diffuse) white matter injury (WMI) are the most important acquired brain lesions of the very and extremely prematurely born neonate. Both carry a high risk for death or adverse neurodevelopmental outcome. The first part of the review discusses the standard of ca...

journal_title：Frontiers in physiology

authors： van Bel F,Vaes J,Groenendaal F

更新日期：2019-03-20 00:00:00

abstract：:In juvenile rats, the carotid body (CB) is the primary sensor of oxygen (O2) and a secondary sensor of carbon dioxide (CO2) in the blood. The CB communicates to the respiratory pattern generator via the carotid sinus nerve, which terminates within the commissural nucleus tractus solitarius (cNTS). While this is not th...

journal_title：Frontiers in physiology

authors： Getsy PM,Coffee GA,Lewis SJ

更新日期：2020-12-17 00:00:00

abstract：:Sepsis is a systemic inflammatory disease with infection, and autophagy has been shown to play an important role in sepsis. This review summarizes the main regulatory mechanisms of autophagy in sepsis and its latest research. Recent studies have shown that autophagy can regulate innate immune processes and acquired im...

journal_title：Frontiers in physiology

authors： Yin X,Xin H,Mao S,Wu G,Guo L

更新日期：2019-08-23 00:00:00

abstract：:Since the late 2010s, Transcranial Ultrasound Stimulation (TUS) has been used experimentally to carryout safe, non-invasive stimulation of the brain with better spatial resolution than Transcranial Magnetic Stimulation (TMS). This innovative stimulation method has emerged as a novel and valuable device for studying br...

journal_title：Frontiers in physiology

authors： Pouget P,Frey S,Ahnine H,Attali D,Claron J,Constans C,Aubry JF,Arcizet F

更新日期：2020-08-19 00:00:00

abstract：:Natural reward is an essential element of any organism's ability to adapt to environmental variation. Its underlying circuits and mechanisms guide the learning process as they help associate an event, or cue, with the perception of an outcome's value. More generally, natural reward serves as the fundamental generator ...

journal_title：Frontiers in physiology

authors： Datta U,van Staaden M,Huber R

更新日期：2018-05-14 00:00:00

abstract：:The ingestion of intact protein or essential amino acids (EAA) stimulates mechanistic target of rapamycin complex-1 (mTORC1) signaling and muscle protein synthesis (MPS) following resistance exercise. The purpose of this study was to investigate the response of myofibrillar-MPS to ingestion of branched-chain amino aci...

journal_title：Frontiers in physiology

authors： Jackman SR,Witard OC,Philp A,Wallis GA,Baar K,Tipton KD

更新日期：2017-06-07 00:00:00

abstract：:Prior peripheral hypoxia induced via remote ischemic preconditioning (IPC) can improve physical performance in male athletes through improved O2 delivery and utilization. Since females may have an innate protective mechanism against ischemia-reperfusion injury, and since muscle metabolism during contraction differs be...

journal_title：Frontiers in physiology

authors： Paradis-Deschênes P,Joanisse DR,Billaut F

更新日期：2017-01-05 00:00:00

abstract：:The mechanisms of atrial fibrillation (AF) are a challenging research topic. The rotor hypothesis states that the AF is sustained by a reentrant wave that propagates around an unexcited core. Cardiac tissue heterogeneities, both structural and cellular, play an important role during fibrillatory dynamics, so that the ...

journal_title：Frontiers in physiology

authors： Ugarte JP,Tobón C,Lopes AM,Machado JAT

更新日期：2018-07-24 00:00:00

abstract：:The detailed behavior of many molecular processes in the cell, such as protein folding, protein complex assembly, and gene regulation, transcription and translation, can often be accurately captured by stochastic chemical kinetic models. We investigate a novel computational problem involving these models - that of fin...

journal_title：Frontiers in physiology

authors： Salehi M,Perkins TJ

更新日期：2010-10-19 00:00:00

abstract：:Elderly healthy individuals have a reduced exercise tolerance and a decreased left ventricle inotropic reserve related to increased vascular afterload, arterial-ventricular load mismatching, physical deconditioning and impaired autonomic regulation (the so called "β-adrenergic desensitization"). Adrenergic responsiven...

journal_title：Frontiers in physiology

authors： Ferrara N,Komici K,Corbi G,Pagano G,Furgi G,Rengo C,Femminella GD,Leosco D,Bonaduce D

更新日期：2014-01-09 00:00:00

abstract：:Troponin I (TnI) is a major regulator of cardiac muscle contraction and relaxation. During physiological and pathological stress, TnI is differentially phosphorylated at multiple residues through different signaling pathways to match cardiac function to demand. The combination of these TnI phosphorylations can exhibit...

journal_title：Frontiers in physiology

authors： Salhi HE,Hassel NC,Siddiqui JK,Brundage EA,Ziolo MT,Janssen PM,Davis JP,Biesiadecki BJ

更新日期：2016-12-15 00:00:00

abstract：:Skeletal muscle is a plastic tissue that undergoes cellular and metabolic adaptations under conditions of increased contractile activity such as exercise. Using adult zebrafish as an exercise model, we previously demonstrated that swimming training stimulates hypertrophy and vascularization of fast muscle fibers, cons...

journal_title：Frontiers in physiology

authors： Rovira M,Arrey G,Planas JV

更新日期：2017-12-18 00:00:00

abstract：:A rich chapter in the history of insect endocrinology has focused on hormonal control of diapause, especially the major roles played by juvenile hormones (JHs), ecdysteroids, and the neuropeptides that govern JH and ecdysteroid synthesis. More recently, experiments with adult diapause in Drosophila melanogaster and th...

journal_title：Frontiers in physiology

authors： Sim C,Denlinger DL

更新日期：2013-07-22 00:00:00

abstract：OBJECTIVES:The dynamic interaction between blood pressure (BP) and cerebral blood flow velocity (CBFV) is not fully understood, especially for CBFV changes lasting longer than 50 s. The interaction between BP and CBFV is relatively well characterized for periods <50 s using transfer function (TF) estimations of phase, ...

journal_title：Frontiers in physiology

authors： Müller MW,Osterreich M

更新日期：2014-08-26 00:00:00

abstract：AIM:The signaling pathways involved in the regulation of cardiac GLUT4 translocation/glucose uptake and CD36 translocation/long-chain fatty acid uptake are not fully understood. We compared in heart/muscle-specific PKC-λ knockout mice the roles of atypical PKCs (PKC-ζ and PKC-λ) in regulating cardiac glucose and fatty ...

journal_title：Frontiers in physiology

authors： Habets DD,Luiken JJ,Ouwens M,Coumans WA,Vergouwe M,Maarbjerg SJ,Leitges M,Bonen A,Richter EA,Glatz JF

更新日期：2012-09-11 00:00:00

abstract：:Background: Nrg4 expression has been linked to brown adipose tissue activity and browning of white adipocytes in mice. Here, we aimed to investigate whether these observations could be translated to humans by investigating NRG4 mRNA and markers of brown/beige adipocytes in human visceral (VAT) and subcutaneous adipose...

journal_title：Frontiers in physiology

authors： Comas F,Martínez C,Sabater M,Ortega F,Latorre J,Díaz-Sáez F,Aragonés J,Camps M,Gumà A,Ricart W,Fernández-Real JM,Moreno-Navarrete JM

更新日期：2019-01-31 00:00:00

abstract：:Pancreatic cancer shows a characteristic tissue structure called desmoplasia, which consists of dense fibrotic stroma surrounding cancer cells. Interactions between pancreatic cancer cells and stromal cells promote invasive growth of cancer cells and establish a specific microenvironment such as hypoxia which further ...

journal_title：Frontiers in physiology

authors： Hamada S,Masamune A,Shimosegawa T

更新日期：2013-11-01 00:00:00

abstract：:[This corrects the article DOI: 10.3389/fphys.2019.01574.]. ...

journal_title：Frontiers in physiology

authors： Figueroa VA,Jara O,Oliva CA,Ezquer M,Ezquer F,Retamal MA,Martínez AD,Altenberg GA,Vargas AA

更新日期：2020-02-11 00:00:00

abstract：:The brain-gut axis plays a critical role in the regulation of different diseases, many of which are characterized by sympathetic dysregulation. However, a direct link between sympathetic dysregulation and gut dysbiosis remains to be illustrated. Bone marrow (BM)-derived immune cells continuously interact with the gut ...

journal_title：Frontiers in physiology

authors： Yang T,Ahmari N,Schmidt JT,Redler T,Arocha R,Pacholec K,Magee KL,Malphurs W,Owen JL,Krane GA,Li E,Wang GP,Vickroy TW,Raizada MK,Martyniuk CJ,Zubcevic J

更新日期：2017-04-12 00:00:00

abstract：:Blood pressure regulation is a prime example of homeostatic regulation. However, some characteristics of the cardiovascular system better match a non-linear self-organized system than a homeostatic one. To determine whether blood pressure regulation is self-organized, we repeated the seminal demonstration of self-orga...

journal_title：Frontiers in physiology

authors： Fortrat JO,Levrard T,Courcinous S,Victor J

更新日期：2016-03-31 00:00:00

abstract：:There are animal species that have adapted to life at high altitude and hypobaric hypoxia conditions in the Andean highlands. One such species is the llama (Lama glama), which seem to have developed efficient protective mechanisms to avoid maladaptation resulting from chronic hypoxia, such as a resistance to the devel...

journal_title：Frontiers in physiology

authors： López V,Moraga FA,Llanos AJ,Ebensperger G,Taborda MI,Uribe E

更新日期：2018-05-29 00:00:00