Testosterone therapy in men: clinical and pharmacological perspectives.

Abstract:

:There is increasing evidence that androgen therapy in men may be effectively applied in several conditions to improve well being and health. Classical indications for androgen therapy in males are represented by primary or secondary hypogonadism, delayed puberty, aplastic anemia and that secondary to chronic renal failure, protein wasting diseases such as trauma, burns, tumors and infectious diseases. Androgen innovating applications in men are represented by aging and visceral obesity associated with the metabolic syndrome. In addition, it is clear that appropriate testosterone treatment can be adequately used in male contraception, provided spermatogenesis is abolished and tolerability is adequate. Due to unphysiological hormone levels achieved by currently available testosterone preparations, new delivery systems have been produced to achieve more physiological and sustained hormone levels and improve tolerability and action at the levels of target tissues. Some of them are now available in several countries and new formulas are under development.

journal_name

J Endocrinol Invest

authors

Gambineri A,Pasquali R

doi

10.1007/BF03343707

keywords:

subject

Has Abstract

pub_date

2000-03-01 00:00:00

pages

196-214

issue

3

eissn

0391-4097

issn

1720-8386

journal_volume

23

pub_type

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