Application of real-time reverse transcription polymerase chain reaction to the detection the matrix, H5 and H7 genes of avian influenza viruses in field samples from South Korea.

abstract：:One coronavirus strain was isolated from brain tissues of ten piglets with evident clinical manifestations of vomiting, diarrhea and dyskinesia in Jilin province in China. Antigenic and genomic characterizations of the virus (isolate PHEV-JLsp09) were based on multiplex PCR and negative staining electron microscopy an...

journal_title：Virology journal

authors： Gao W,Zhao K,Zhao C,Du C,Ren W,Song D,Lu H,Chen K,Li Z,Lan Y,Xie S,He W,Gao F

更新日期：2011-03-21 00:00:00

abstract：BACKGROUND:R849 is a neurovirulent γ₁34.5 gene-deficient form of herpes simplex virus type 1 (HSV-1) and has LacZ genes at the deleted sites of the γ₁34.5 gene. HF is a spontaneously occurring, fusogenic HSV-1 strain. The purpose of this work was to generate a virus that has the syncytial character of HF, while preserv...

journal_title：Virology journal

authors： Takaoka H,Takahashi G,Ogawa F,Imai T,Iwai S,Yura Y

更新日期：2011-06-10 00:00:00

abstract：BACKGROUND:Hepatitis C virus (HCV) infection is a major public health problem with more than 170 million cases of chronic infections worldwide. There is no protective vaccine currently available for HCV, therefore the development of novel strategy to prevent chronic infection is important. We reported earlier that a re...

journal_title：Virology journal

authors： Chandra PK,Hazari S,Poat B,Gunduz F,Prabhu R,Liu G,Burioni R,Clementi M,Garry RF,Dash S

更新日期：2010-06-07 00:00:00

abstract：BACKGROUND:Entry of Ebolavirus to the target cells is mediated by the viral glycoprotein GP. The native GP exists as a homotrimer on the virions and contains two subunits, a surface subunit (GP1) that is involved in receptor binding and a transmembrane subunit (GP2) that mediates the virus-host membrane fusion. Previou...

journal_title：Virology journal

authors： Manicassamy B,Rong L

更新日期：2009-06-08 00:00:00

abstract：BACKGROUND:Aleutian mink disease virus (AMDV) is the cause of a chronic immune complex disease, Aleutian disease (AD), which is common in mink-producing countries. In 2005, implementation of an AMDV eradication programme in Finland created a need for an automated high-throughput assay. The aim of this study was to vali...

journal_title：Virology journal

authors： Knuuttila A,Aronen P,Eerola M,Gardner IA,Virtala AM,Vapalahti O

更新日期：2014-08-08 00:00:00

abstract：BACKGROUND:Foot-and mouth disease (FMD) is an acute, febrile, and contagious vesicular disease affecting cloven-hoofed animals. Some animals may become persistent infected carriers when they contact FMD virus (FMDV), and persistent infected animals are a dangerous factor to cause FMD outbreak. FINDINGS:300 OP (oesopha...

journal_title：Virology journal

authors： Bao HF,Li D,Sun P,Zhou Q,Hu J,Bai XW,Fu YF,Lu ZJ,Liu ZX

更新日期：2011-12-14 00:00:00

abstract：BACKGROUND:Influenza A virus poses a continuous threat to global public health. Design of novel universal drugs and vaccine requires a careful analysis of different strains of Influenza A viral genome from diverse hosts and subtypes. We performed a systematic in silico analysis of Influenza A viral segments of all avai...

journal_title：Virology journal

authors： ElHefnawi M,Alaidi O,Mohamed N,Kamar M,El-Azab I,Zada S,Siam R

更新日期：2011-01-27 00:00:00

abstract：BACKGROUND:Enteroviruses (EVs) are the leading cause of aseptic meningitis, which is the most frequent central nervous system infection worldwide. We aimed to characterize the EVs involved in an aseptic meningitis outbreak in Korea in 2008. In Korea, Echovirus type 30 (E30) and E6 have been associated with outbreaks an...

journal_title：Virology journal

authors： Kim HJ,Kang B,Hwang S,Hong J,Kim K,Cheon DS

更新日期：2012-02-15 00:00:00

abstract：BACKGROUND:The Urabe AM9 vaccine strain of mumps virus contains two variants of V protein: VWT (of HN-A1081 viral population) and VGly (of HN-G1081). The V protein is a promoting factor of viral replication by blocking the IFN antiviral pathway. FINDINGS:We studied the relationship between V protein variants and IFN-α...

journal_title：Virology journal

authors： Rosas-Murrieta NH,Santos-López G,Reyes-Leyva J,Jurado FS,Herrera-Camacho I

更新日期：2011-05-13 00:00:00

abstract：BACKGROUND:Human papillomavirus (HPV) E6 and E7 oncoproteins play a crucial role in HPV-related diseases, such as cervical cancer, and can be used as ideal targets for therapeutic vaccines. Human leukocyte antigen (HLA) participates in the immune response to block HPV infection and invasion by its target/recognition fu...

journal_title：Virology journal

authors： He J,Yang Y,Chen Z,Liu Y,Bao S,Zhao Y,Ding X

更新日期：2019-05-28 00:00:00

abstract：BACKGROUND:Avian hepatitis E virus (aHEV) has been associated with hepatitis-splenomegaly syndrome (HSS) in chickens along with asymptomatic subclinical infection in many cases. So far, four genotypes have been described, which cause infection in chickens, specifically in broiler breeders and layer chickens. In the pre...

journal_title：Virology journal

authors： Iqbal T,Rashid U,Idrees M,Afroz A,Kamili S,Purdy MA

更新日期：2019-11-21 00:00:00

abstract：:Herpes simplex virus (HSV) infection is one of the most common viral sexually transmitted diseases worldwide. The first time infection of the mother may lead to severe illness in pregnancy and may be associated with virus transmission from mother to foetus/newborn. Since the incidence of this sexually transmitted infe...

journal_title：Virology journal

authors： Anzivino E,Fioriti D,Mischitelli M,Bellizzi A,Barucca V,Chiarini F,Pietropaolo V

更新日期：2009-04-06 00:00:00

abstract：BACKGROUND:Previously, we showed that the tetraspanin membrane protein CD63 mediates both early and post-integration stages of the HIV-1 replication cycle. The temporal roles of CD63 were discerned using monoclonal antibodies and small interfering RNAs (siRNAs) to block CD63 function, and determining which of the seque...

journal_title：Virology journal

authors： Li G,Endsley MA,Somasunderam A,Gbota SL,Mbaka MI,Murray JL,Ferguson MR

更新日期：2014-02-08 00:00:00

abstract：:Secondary pneumonia due to Staphylococcus aureus (S. aureus) causes significant morbidity and mortality. The aim of the research was designed a novel DNA vaccine encoding the Mycobacterium tuberculosis secreted antigen Ag85A fused with the influenza A virus (IAV) HA2 protein to provide protection against both influenz...

journal_title：Virology journal

authors： Dai J,Pei D,Wang B,Kuang Y,Ren L,Cao K,Zuo B,Shao J,Li S,Jiang Z,Li H,Li M

更新日期：2013-01-31 00:00:00

abstract：:Fatal influenza A virus infection is a major threat to public health throughout the world. Lung macrophages and neutrophils have critical roles for both the pathogenesis and viral clearance of fatal viral infections. These are complicated by the interaction of innate immunity and adaptive immunity against viral infect...

journal_title：Virology journal

authors： Lv J,Hua Y,Wang D,Liu A,An J,Li A,Wang Y,Wang X,Jia N,Jiang Q

更新日期：2014-03-26 00:00:00

abstract：BACKGROUND:Kadipiro virus (KDV) belongs to the Reoviridae family, which consists of segmented, non-enveloped, double-stranded RNA viruses. It has previously been isolated from Culex, Anopheles, Armigeres and Aedes mosquitoes in Indonesia and China. Here, we describe the isolation and characterization of SDKL1625 from A...

journal_title：Virology journal

authors： Zhang W,Li F,Liu A,Lin X,Fu S,Song J,Liu G,Shao N,Tao Z,Wang Q,He Y,Lei W,Liang G,Xu A,Zhao L,Wang H

更新日期：2018-04-06 00:00:00

abstract：BACKGROUND:The BK Polyomavirus (BKPyV) and JC polyomavirus (JCPyV) infections are widespread in human population and have been associated with severe kidney and brain disorders, respectively. The viruses remain latent primarily in reno-urinary tract, reactivating only in case of a compromised immune system. The seroepi...

journal_title：Virology journal

authors： Hussain I,Tasneem F,Umer M,Pervaiz A,Raza M,Arshad MI,Shahzad N

更新日期：2017-04-24 00:00:00

abstract：BACKGROUND:Hepatitis B virus (HBV) infection is a serious health problem worldwide. Treatment recommendation and response are mainly indicated by viral load, e antigen (HBeAg) seroconversion, and ALT levels. The S antigen (HBsAg) seroconversion is much less frequent. Since HBeAg can be negative in the presence of high ...

journal_title：Virology journal

authors： Lian M,Zhou X,Wei L,Qiu S,Zhou T,Li L,Gu X,Luo M,Zheng X

更新日期：2007-09-24 00:00:00

abstract：BACKGROUND:Hepatitis C virus (HCV) encodes several proteins that interfere with the host cell antiviral response. Previously, the serine protease NS3/4A was shown to inhibit IFN-beta gene expression by blocking dsRNA-activated retinoic acid-inducible gene I (RIG-I) and Toll-like receptor 3 (TLR3)-mediated signaling pat...

journal_title：Virology journal

authors： Kaukinen P,Sillanpää M,Kotenko S,Lin R,Hiscott J,Melén K,Julkunen I

更新日期：2006-09-01 00:00:00

abstract：BACKGROUND:H5N1 highly pathogenic avian influenza virus (HPAIV) is continuously circulating in many Asian countries and threatening poultry industry and human population. Vaccination is the best strategy to control H5N1 HPAIV infection in poultry and transmission to human population. The aim of this study is to identif...

journal_title：Virology journal

authors： Zhang W,Tu J,Zhao Z,Chen H,Jin M

更新日期：2012-05-23 00:00:00

abstract：BACKGROUND:Mumps virus is a negative-sense, single stranded RNA virus consisting of a ribonucleocapsid core enveloped by a lipid membrane derived from host cell, which causes mumps disease preventable by vaccination. Since virus lipid envelope and glycosylation pattern are not encoded by the virus but dependent on the ...

journal_title：Virology journal

authors： Brgles M,Bonta M,Šantak M,Jagušić M,Forčić D,Halassy B,Allmaier G,Marchetti-Deschmann M

更新日期：2016-01-14 00:00:00

abstract：BACKGROUND:Farmington virus (FARV) is a rhabdovirus that was isolated from a wild bird during an outbreak of epizootic eastern equine encephalitis on a pheasant farm in Connecticut, USA. FINDINGS:Analysis of the nearly complete genome sequence of the prototype CT AN 114 strain indicates that it encodes the five canoni...

journal_title：Virology journal

authors： Palacios G,Forrester NL,Savji N,Travassos da Rosa AP,Guzman H,Detoy K,Popov VL,Walker PJ,Lipkin WI,Vasilakis N,Tesh RB

更新日期：2013-07-01 00:00:00

abstract：BACKGROUND:During the pandemic [Influenza A(H1N1)pdm09] period in 2009-2010, an influenza A (Inf-A) virus with H1N2 subtype (designated as A/Eastern India/N-1289/2009) was detected from a 25 years old male from Mizoram (North-eastern India). OBJECTIVE:To characterize full genome of the H1N2 influenza virus. METHODS:F...

journal_title：Virology journal

authors： Mukherjee TR,Agrawal AS,Chakrabarti S,Chawla-Sarkar M

更新日期：2012-10-11 00:00:00

abstract：BACKGROUND:Mumps virus (MuV) is a highly infectious paramyxovirus closely related to measles virus (MeV). Despite the availability of a mumps vaccine, outbreaks continue to occur and no treatment options are available. Vitamin A and other naturally occurring retinoids inhibit the replication of MeV in vitro. METHODS:A...

journal_title：Virology journal

authors： Soye KJ,Trottier C,Di Lenardo TZ,Restori KH,Reichman L,Miller WH Jr,Ward BJ

更新日期：2013-11-14 00:00:00

abstract：BACKGROUND:A number of gene therapy applications would benefit from vectors capable of expressing multiple genes. In this study we explored the feasibility and efficiency of expressing two or three transgenes in HIV-1 based lentiviral vector. Bicistronic and tricistronic self-inactivating lentiviral vectors were constr...

journal_title：Virology journal

authors： Chinnasamy D,Milsom MD,Shaffer J,Neuenfeldt J,Shaaban AF,Margison GP,Fairbairn LJ,Chinnasamy N

更新日期：2006-03-15 00:00:00

abstract：BACKGROUND:Progressive multifocal leukoencephalopathy (PML) onset, caused by Polyomavirus JC (JCPyV) in patients affected by immune-mediated diseases during biological treatment, raised concerns about the safety profile of these agents. Therefore, the aims of this study were the JCPyV reactivation monitoring and the no...

journal_title：Virology journal

authors： Bellizzi A,Anzivino E,Rodio DM,Cioccolo S,Scrivo R,Morreale M,Pontecorvo S,Ferrari F,Di Nardo G,Nencioni L,Carluccio S,Valesini G,Francia A,Cucchiara S,Palamara AT,Pietropaolo V

更新日期：2013-09-30 00:00:00

abstract：:The suitability of V4 vaccine coated on cracked local grain (maize) and its husks and used for oral vaccination of chickens was assessed. Seventy-two (72) birds aged three (3) weeks and above were divided into six groups of twelve (12) birds per group. The birds were bled to determine their prevaccination HI antibody ...

journal_title：Virology journal

authors： Olabode AO,Ndako JA,Echeonwu GO,Nwankiti OO,Chukwuedo AA

更新日期：2010-03-23 00:00:00

abstract：BACKGROUND:Foot-and-mouth disease (FMD) is a highly contagious disease of livestock which causes severe economic loss in cloven-hoofed animals. Vaccination is still a major strategy in developing countries to control FMD. Currently, inactivated vaccine of FMDV has been used in many countries with limited success and sa...

journal_title：Virology journal

authors： Cao Y,Lu Z,Sun P,Fu Y,Tian F,Hao X,Bao H,Liu X,Liu Z

更新日期：2011-02-23 00:00:00

abstract：BACKGROUND:Co-circulation of multiple dengue virus serotypes has been reported from many parts of the world including India, however concurrent infection with more than one serotype of dengue viruses in the same individual is rarely documented. An outbreak of dengue hemorrhagic fever/dengue shock syndrome (DHF/DSS) occ...

journal_title：Virology journal

authors： Bharaj P,Chahar HS,Pandey A,Diddi K,Dar L,Guleria R,Kabra SK,Broor S

更新日期：2008-01-09 00:00:00

abstract：BACKGROUND:The UL54 protein of Duck Enteritis Virus (DEV) is a homolog of herpes simplex virus-1 (HSV-1) immediate-early infectious cell protein 27 (ICP27), a multifunctional protein essential for viral infection. Nonetheless, there is little information on the UL54 protein of DEV. METHODS:The UL54 gene was cloned int...

journal_title：Virology journal

authors： Liu C,Cheng A,Wang M,Chen S,Jia R,Zhu D,Liu M,Sun K,Yang Q,Chen X

更新日期：2015-11-25 00:00:00