The HDAC Inhibitor Phenylbutyrate Reverses Effects of Neonatal Ventral Hippocampal Lesion in Rats.

abstract：:The use of smartphone apps for research and clinical care in mental health has become increasingly popular, especially within youth mental health. In particular, digital phenotyping, the monitoring of data streams from a smartphone to identify proxies for functional outcomes like steps, sleep, and sociability, is of i...

journal_title：Frontiers in psychiatry

authors： Wisniewski H,Henson P,Torous J

更新日期：2019-09-23 00:00:00

abstract：:Adenosine-to-inosine (A-to-I) RNA editing is a co-/posttranscriptional modification of double-stranded RNA, catalyzed by the adenosine deaminase acting on RNA (ADAR) family of enzymes, which results in recognition of inosine as guanosine by translational and splicing machinery causing potential recoding events in amin...

journal_title：Frontiers in psychiatry

authors： Dick ALW,Khermesh K,Paul E,Stamp F,Levanon EY,Chen A

更新日期：2019-04-26 00:00:00

abstract：Background:Loss aversion is a central and well operationalized trait behavior that describes the tendency for humans to strongly prefer avoiding losses to making equivalent gains. Human decision-making is thus biased toward safer choices. Aim:The aim of this study was to explore the relationship between loss aversion ...

journal_title：Frontiers in psychiatry

authors： Hadlaczky G,Hökby S,Mkrtchian A,Wasserman D,Balazs J,Machín N,Sarchiapone M,Sisask M,Carli V

更新日期：2018-04-05 00:00:00

abstract：Background:Chronic insomnia is common in patients with arteriosclerotic cerebral small vessel disease (CSVD) and aggravates the cognitive impairment caused by CSVD. Low-dose trazodone is effective in treating insomnia, but it is unclear whether it can also improve cognitive function in CSVD patients. This study was per...

journal_title：Frontiers in psychiatry

authors： Wang J,Liu S,Zhao C,Han H,Chen X,Tao J,Lu Z

更新日期：2020-06-30 00:00:00

abstract：:Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by lack of attention to social cues in the environment, including speech. Hypersensitivity to sensory stimuli, such as loud noises, is also extremely common in youth with ASD. While a link between sensory hypersensitivity and impaired social...

journal_title：Frontiers in psychiatry

authors： Hernandez LM,Green SA,Lawrence KE,Inada M,Liu J,Bookheimer SY,Dapretto M

更新日期：2020-04-24 00:00:00

abstract：:Introduction: Evidence from developed countries shows the efficacy of computer-assisted cognitive-behavioral therapy (cCBT) in addressing adolescent depression in home and/or school settings. This paper presents the results of a randomized controlled trial (RCT) of a brief therapist-guided cCBT intervention for adoles...

journal_title：Frontiers in psychiatry

authors： Martínez V,Rojas G,Martínez P,Gaete J,Zitko P,Vöhringer PA,Araya R

更新日期：2019-07-30 00:00:00

abstract：PURPOSE:Excessive daytime sleepiness is highly prevalent in the general population, is the hallmark of narcolepsy, and is linked to significant morbidity. Clinical assessment of sleepiness remains challenging and the common objective multiple sleep latency test (MSLT) and subjective Epworth sleepiness scale (ESS) metho...

journal_title：Frontiers in psychiatry

authors： Prasad B,Choi YK,Weaver TE,Carley DW

更新日期：2011-06-07 00:00:00

abstract：:Aim: With the introduction of "Electronic Medical Record" (EMR) a wealth of digital data has become available. This provides a unique opportunity for exploring precedents for seclusion. This study explored the feasibility of text mining analysis in the EMR to eventually help reduce the use of seclusion in psychiatry. ...

journal_title：Frontiers in psychiatry

authors： Hazewinkel MC,de Winter RFP,van Est RW,van Hyfte D,Wijnschenk D,Miedema N,Hoencamp E

更新日期：2019-04-11 00:00:00

abstract：:Alongside biological, psychological, and social risk factors, psychotic syndromes may be related to disturbances of neuronal migration. This highly complex process characterizes the developing brain of the fetus, the early postnatal brain, and the adult brain, as reflected by changes within the subventricular zone and...

journal_title：Frontiers in psychiatry

authors： Lucchese G,Flöel A,Stahl B

更新日期：2020-05-08 00:00:00

abstract：:The extraordinary health emergency of the COVID-19 pandemic represents a new challenge for mental health researchers and clinical practitioners. The related containment measures may be a risk factor for psychological distress and mood disorders, especially in at-risk populations. This study aims to explore the impact ...

journal_title：Frontiers in psychiatry

authors： Spinola O,Liotti M,Speranza AM,Tambelli R

更新日期：2020-11-17 00:00:00

abstract：:Autism spectrum disorder (ASD) and schizophrenia (SZ) are heterogenous neurodevelopmental disorders that overlap in symptom presentation. The purpose of this study was to specify overlapping symptom domains and to identify symptoms that can reliably differentiate adults with ASD (n = 53), SZ (n = 39), and typical deve...

journal_title：Frontiers in psychiatry

authors： Trevisan DA,Foss-Feig JH,Naples AJ,Srihari V,Anticevic A,McPartland JC

更新日期：2020-06-11 00:00:00

abstract：:Abnormal functional connectivity (FC) within discrete brain networks is involved in the pathophysiology of obsessive-compulsive disorder (OCD) with inconsistent results. In the present study, we investigated the FC patterns of 40 drug-naive patients with OCD and 38 healthy controls (HCs) through an unbiased voxel-wise...

journal_title：Frontiers in psychiatry

authors： Cui G,Ou Y,Chen Y,Lv D,Jia C,Zhong Z,Yang R,Wang Y,Meng X,Cui H,Li C,Sun Z,Wang X,Guo W,Li P

更新日期：2020-03-03 00:00:00

abstract：:Major depression is a psychiatric disorder with high prevalence in the general population, with increasing expression in adolescence, about 14% in young people. Frequently, it presents as a chronic condition, showing no remission even after several pharmacological treatments and persisting in adult life. Therefore, di...

journal_title：Frontiers in psychiatry

authors： Galvão-Coelho NL,Galvão ACM,da Silva FS,de Sousa MBC

更新日期：2017-09-21 00:00:00

abstract：Background:Among Muslim patients, a common cultural concept of distress is the notion that jinn may be the cause of mental health problems, especially in the presence of hallucinations. Objective:This study examines the frequency with which this attribution style is manifest in a specific psychiatric outpatient popula...

journal_title：Frontiers in psychiatry

authors： Lim A,Hoek HW,Ghane S,Deen M,Blom JD

更新日期：2018-03-28 00:00:00

abstract：:Abnormal amplitude of low-frequency fluctuation has been implicated in heroin addiction. However, previous studies lacked consistency and didn't consider the impact of confounding factors such as methadone and alcohol. Fifty-one heroin-dependent (HD) individuals and 40 healthy controls underwent resting-state function...

journal_title：Frontiers in psychiatry

authors： Luo J,Yang R,Yang W,Duan C,Deng Y,Zhang J,Chen J,Liu J

更新日期：2020-07-03 00:00:00

abstract：:Background: Major depressive disorder (MDD) is associated with a wide range of cognitive deficits. However, it remains unclear whether there will be a major cognitive deficit independently caused by depression at acute episodes of MDD. Method: A comprehensive neurocognitive test battery was used to assess the executiv...

journal_title：Frontiers in psychiatry

authors： Liu J,Dong Q,Lu X,Sun J,Zhang L,Wang M,Wan P,Guo H,Zhao F,Ju Y,Yan D,Li H,Fang H,Guo W,Liao M,Zhang X,Zhang Y,Liu B,Li L

更新日期：2019-11-12 00:00:00

abstract：:Background: The developmental period from 0 to 25 years is a vulnerable time during which children and young people experience many psychosocial and neurobiological changes and an increased incidence of mental illness. New clinical services for children and young people aged 0 to 25 years may represent a radical trans...

journal_title：Frontiers in psychiatry

authors： Fusar-Poli P

更新日期：2019-06-07 00:00:00

abstract：:Antipsychotic-induced weight gain is one of the most common adverse effects of antipsychotic treatment. However, there are no well-established interventions for the weight gain yet. In this study, we pooled the data from two clinical trials, which were originally examining the efficacy of betahistine and the efficacy ...

journal_title：Frontiers in psychiatry

authors： Kang D,Jing Z,Li R,Hei G,Shao T,Li L,Sun M,Yang Y,Wang Y,Wang X,Long Y,Huang X,Wu R

更新日期：2018-11-27 00:00:00

abstract：INTRODUCTION:Ruminative (abstract verbal) processing during recall of aversive autobiographical memories may serve to dampen their short-term affective impact. Experimental studies indeed demonstrate that verbal processing of non-autobiographical material and positive autobiographical memories evokes weaker affective r...

journal_title：Frontiers in psychiatry

authors： Slofstra C,Eisma MC,Holmes EA,Bockting CLH,Nauta MH

更新日期：2017-05-30 00:00:00

abstract：:Cocaine addiction is a widespread psychiatric condition still waiting for approved efficacious medications. Previous studies suggested that simultaneous activation of nociceptin opioid (NOP) and mu opioid (MOP) receptors could be a successful strategy to treat cocaine addiction, but the paucity of molecules co-activat...

journal_title：Frontiers in psychiatry

authors： Shen Q,Deng Y,Ciccocioppo R,Cannella N

更新日期：2017-11-13 00:00:00

abstract：Introduction:The Bermond-Vorst Alexithymia Questionnaire (BVAQ) has been validated in student samples and small clinical samples, but not in the general population; thus, representative general-population norms are lacking. Aim:We examined the factor structure of the BVAQ in Longitudinal Internet Studies for the Socia...

journal_title：Frontiers in psychiatry

authors： de Vroege L,Emons WHM,Sijtsma K,van der Feltz-Cornelis CM

更新日期：2018-04-23 00:00:00

abstract：:As established in a wealth of studies subtle motor and sensory neurological abnormalities or neurological soft signs (NSS) are frequently found in patients with schizophrenia at any stage of their illness. However, the potential impact of chronicity and age on NSS was scarcely investigated. Therefore, we assessed NSS ...

journal_title：Frontiers in psychiatry

authors： Herold CJ,Lässer MM,Seidl UW,Hirjak D,Thomann PA,Schröder J

更新日期：2018-03-26 00:00:00

abstract：:Previous work from our group and others utilizing animal models have demonstrated long-lasting structural and functional alterations in the meso-cortico-striatal dopamine pathway following prenatal cocaine (PCOC) treatment. We have shown that PCOC treatment results in augmented D1-induced cyclic AMP (cAMP) and cocaine...

journal_title：Frontiers in psychiatry

authors： Tropea TF,Kabir ZD,Kaur G,Rajadhyaksha AM,Kosofsky BE

更新日期：2011-12-07 00:00:00

abstract：:Objectives: While evidence that episodes of mania in bipolar I are associated with changes in bioenergetic and regional cerebral blood flow (rCBF) and cerebral blood flow velocity (rCBFV), both the regions and the extent of these changes have not yet been defined. Therefore, we determined the pattern of regional cereb...

journal_title：Frontiers in psychiatry

authors： Wang Y,Liu X,Li P,Zhou H,Yang L,Zheng L,Xie P,Li L,Liao DJ,Liu Q,Fang D

更新日期：2018-07-04 00:00:00

abstract：:Alcohol use disorder (AUD) is a devastating public health problem in which both genetic and environmental factors play a role. Growing evidence supports that epigenetic regulation is one major mechanism in neuroadaptation that contributes to development of AUD. Meanwhile, epigenetic patterns can be modified by various...

journal_title：Frontiers in psychiatry

authors： Chen J,Hutchison KE,Bryan AD,Filbey FM,Calhoun VD,Claus ED,Lin D,Sui J,Du Y,Liu J

更新日期：2018-11-15 00:00:00

abstract：:Previous work has demonstrated that goal-directed control of alcohol-seeking and other drug-related behaviors is reduced following extended self-administration and drug exposure. Here, we examined how the magnitude of stimulus influences on responding changes across similar training and drug exposure. Rats self-admini...

journal_title：Frontiers in psychiatry

authors： Corbit LH,Janak PH

更新日期：2016-10-10 00:00:00

abstract：:Background: Australia is a high-income country with increasing income inequality. It is unclear whether Australia's well-developed mental healthcare system is making a difference to population mental health and the Federal Government has targeted outcomes accountability in service funding strategies. In high-income co...

journal_title：Frontiers in psychiatry

authors： Isaacs AN,Enticott J,Meadows G,Inder B

更新日期：2018-10-26 00:00:00

abstract：:Background: Primary indicated prevention in individuals at-risk for psychosis has the potential to improve the outcomes of this disorder. The ability to detect the majority of at-risk individuals is the main barrier toward extending benefits for the lives of many adolescents and young adults. Current detection strateg...

journal_title：Frontiers in psychiatry

authors： Fusar-Poli P,Oliver D,Spada G,Patel R,Stewart R,Dobson R,McGuire P

更新日期：2019-03-13 00:00:00

abstract：:Diminished orienting to social stimuli, and particularly to faces, is a core feature of autism spectrum disorders (ASDs). Impaired face processing has been linked to atypical attention processes that trigger a cascade of pathological development contributing to impaired social communication. The aim of the present stu...

journal_title：Frontiers in psychiatry

authors： Bochet A,Franchini M,Kojovic N,Glaser B,Schaer M

更新日期：2021-01-13 00:00:00

abstract：Background:Disorganization of semantic memory in patients with schizophrenia has been studied by referring to their category fluency performance. Recently, data-mining techniques such as singular value decomposition (SVD) analysis have been reported to be effective in elucidating the latent semantic memory structure in...

journal_title：Frontiers in psychiatry

authors： Sumiyoshi C,Fujino H,Sumiyoshi T,Yasuda Y,Yamamori H,Fujimoto M,Hashimoto R

更新日期：2018-03-21 00:00:00