Pleomorphic adenoma of cervical heterotopic salivary glands.

abstract：BACKGROUND:This is a retrospective cross sectional study aimed to verify whether Multiplex Ligation-dependent Probe Amplification (MLPA), a quantitative molecular assay, may represent a valuable reflex test in breast cancer with equivocal HER2 expression by immunohistochemistry and HER2 gene signals/nucleus (s/n) rangi...

journal_title：Journal of experimental & clinical cancer research : CR

authors： Ercolani C,Marchiò C,Di Benedetto A,Fabi A,Perracchio L,Vici P,Sperati F,Buglioni S,Arena V,Pescarmona E,Sapino A,Terrenato I,Mottolese M

更新日期：2017-10-13 00:00:00

abstract：:In the original publication of this manuscript [1], Fig. 5E lower panel was incorrect due to an error in the preparation of these figures for publication. It was noticed that in the lower panel of Fig. 5E, one mouse image of ApoE-/- + PBS group (upper) was a photograph coming from ApoE-/- + BAPN pre-treatment group (l...

journal_title：Journal of experimental & clinical cancer research : CR

authors： Lai H,Zhao X,Qin Y,Ding Y,Chen R,Li G,Labrie M,Ding Z,Zhou J,Hu J,Ma D,Fang Y,Gao Q

更新日期：2019-10-15 00:00:00

abstract：BACKGROUND:In response to diverse genotoxic stimuli p53 is activated as transcription factor to exert its tumor-suppressor function. P53 activation requires protein stabilization, nuclear localization and posttranslational modifications in key residues that may influence p53 selection of target genes. Among them, serin...

journal_title：Journal of experimental & clinical cancer research : CR

authors： Garufi A,D'Orazi G

更新日期：2014-09-27 00:00:00

abstract：BACKGROUND:Partial epithelial mesenchymal transition (p-EMT) was found to play a potential role in the initial stage of metastasis in human head and neck squamous cell carcinoma (HNSCC). Some long noncoding RNAs (lncRNAs) have been reported to function as promoters or inhibitors of cancer metastasis. This study aimed t...

journal_title：Journal of experimental & clinical cancer research : CR

authors： Xiong HG,Li H,Xiao Y,Yang QC,Yang LL,Chen L,Bu LL,Zhang WF,Zhang JL,Sun ZJ

更新日期：2019-06-25 00:00:00

abstract：:This study was carried out to provide extensive information obtained from statistical analysis of laryngeal endocrinomas for the use of investigators working in this particular research field. A total of 278 patients with both typical and atypical varieties of carcinoids, and with small/oat cell carcinomas (SCC/OCC) e...

journal_title：Journal of experimental & clinical cancer research : CR

authors： Soga J,Osaka M,Yakuwa Y

更新日期：2002-03-01 00:00:00

abstract：BACKGROUND:Colon cancer is invariably accompanied by altered coagulation activity; however, the precise role of phosphatidylserine (PS) in the hypercoagulable state of colon cancer patients remains unclear. We explored the exposure of PS on platelets and microparticles (MPs), and evaluate its role in procoagulant activ...

journal_title：Journal of experimental & clinical cancer research : CR

authors： Zhao L,Bi Y,Kou J,Shi J,Piao D

更新日期：2016-03-25 00:00:00

abstract：BACKGROUD:Accumulating evidences indicate that circular RNAs (circRNAs), a class of non-coding RNAs, play important roles in tumorigenesis. However, the function of circRNAs in triple negative breast cancer (TNBC) is largely unknown. METHODS:We performed circRNA microarrays to identify circRNAs that are aberrantly exp...

journal_title：Journal of experimental & clinical cancer research : CR

authors： He R,Liu P,Xie X,Zhou Y,Liao Q,Xiong W,Li X,Li G,Zeng Z,Tang H

更新日期：2017-10-16 00:00:00

abstract：BACKGROUND:The epithelial-mesenchymal transition (EMT) is crucial for metastasis and positively regulated by calcium-related signaling. The melastatin-related transient receptor potential 7 (TRPM7) regulates a non-selective cation channel and promotes cancer metastasis. However, the mechanisms underlying the action of ...

journal_title：Journal of experimental & clinical cancer research : CR

authors： Liu L,Wu N,Wang Y,Zhang X,Xia B,Tang J,Cai J,Zhao Z,Liao Q,Wang J

更新日期：2019-02-28 00:00:00

abstract：BACKGROUND:Oncogenic roles of epidermal growth factor receptor pathway substrate no.8 (EPS8) have been widely reported in various tumors, making targeting of EPS8 an appealing prospect. Here, we describe the role of EPS8 in acute myeloid leukemia (AML) and consider the potential of EPS8 as an anti-AML target. Nuclear l...

journal_title：Journal of experimental & clinical cancer research : CR

authors： Chen Y,Xie X,Wu A,Wang L,Hu Y,Zhang H,Li Y

更新日期：2018-01-22 00:00:00

abstract：:Our previous studies have demonstrated the significant enzymatic activity of glycogen phosphorylase (GP) in the gastric carcinoma and proliferating cells of particular intestinal metaplasia (IM). This paper reviewed the identification of the GP isoform in the gastrointestinal carcinoma, and the investigation on the ro...

journal_title：Journal of experimental & clinical cancer research : CR

authors： Shimada S,Tashima S,Yamaguchi K,Matsuzaki H,Ogawa M

更新日期：1999-03-01 00:00:00

abstract：BACKGROUND:Growing evidences indicate that circular RNAs (circRNAs) play an important role in the regulation of biological behavior of tumor. We aim to explore the role of circRNA in glioma and elucidate how circRNA acts. METHODS:Real-time PCR was used to examine the expression of circPTN in glioma tissues and normal ...

journal_title：Journal of experimental & clinical cancer research : CR

authors： Chen J,Chen T,Zhu Y,Li Y,Zhang Y,Wang Y,Li X,Xie X,Wang J,Huang M,Sun X,Ke Y

更新日期：2019-09-11 00:00:00

abstract：UNLABELLED:Stem cells are a relevant source of information about cellular differentiation, molecular processes and tissue homeostasis, but also one of the most putative biological tools to treat degenerative diseases. This review focuses on human stem cells clinical and experimental applications. Our aim is to take a c...

journal_title：Journal of experimental & clinical cancer research : CR

authors： Lodi D,Iannitti T,Palmieri B

更新日期：2011-01-17 00:00:00

abstract：BACKGROUND:The aim of this study was to evaluate the potential association between single nucleotide polymorphisms related response to radiotherapy injury, such as genes related to DNA repair or enzymes involved in anti-oxidative activities. The paper aims to identify marker genes able to predict an increased risk of l...

journal_title：Journal of experimental & clinical cancer research : CR

authors： Falvo E,Strigari L,Citro G,Giordano C,Boboc G,Fabretti F,Bruzzaniti V,Bellesi L,Muti P,Blandino G,Pinnarò P

更新日期：2012-01-24 00:00:00

abstract：BACKGROUND:To investigate influencing factors of the metastatic lymph nodes ratio (MLR) and whether it is related to survival in patients with gastric adenocarcinoma. METHODS:We retrospectively evaluated the clinical features of 121 patients with gastric adenocarcinoma enrolled in our hospital between 2000 and 2007. T...

journal_title：Journal of experimental & clinical cancer research : CR

authors： Yu JW,Wu JG,Zheng LH,Zhang B,Ni XC,Li XQ,Jiang BJ

更新日期：2009-04-26 00:00:00

abstract：BACKGROUND:CD147 plays a critical role in the invasive and metastatic activity of hepatocellular carcinoma (HCC) cells by stimulating the surrounding fibroblasts to express matrix metalloproteinases (MMPs). Tumor cells adhesion to extracellular matrix (ECM) proteins is the first step to the tumor metastasis. MMPs degra...

journal_title：Journal of experimental & clinical cancer research : CR

authors： Qian AR,Zhang W,Cao JP,Yang PF,Gao X,Wang Z,Xu HY,Weng YY,Shang P

更新日期：2008-10-11 00:00:00

abstract：BACKGROUND:Aberrant expression of Wiskott-Aldrich syndrome protein interacting protein family member 1 (WIPF1) contributes to the invasion and metastasis of several malignancies. However, the role of WIPF1 in human pancreatic ductal adenocarcinoma (PDAC) remains poorly understood. METHODS:Human pancreatic cancer sampl...

journal_title：Journal of experimental & clinical cancer research : CR

authors： Pan Y,Lu F,Xiong P,Pan M,Zhang Z,Lin X,Pan M,Huang H

更新日期：2018-07-24 00:00:00

abstract：BACKGROUND:As the expression of human sperm protein 17 (Sp17) in normal tissue is limited and the function is obscure, its aberrant expression in malignant tumors makes it to be a candidated molecular marker for tumor imaging diagnosis and targeting therapy of the diseases.The aim of this research is to evaluate the ta...

journal_title：Journal of experimental & clinical cancer research : CR

authors： Li FQ,Zhang SX,An LX,Gu YQ

更新日期：2011-03-03 00:00:00

abstract：BACKGROUND:Infection with the hepatitis B virus (HBV) is closely associated with the development of hepatocellular carcinoma (HCC). The osmoregulatory transcription factor nuclear factor of activated T-cells 5 (NFAT5) has been shown to play an important role in the development of many types of human cancers. The role o...

journal_title：Journal of experimental & clinical cancer research : CR

authors： Qin X,Li C,Guo T,Chen J,Wang HT,Wang YT,Xiao YS,Li J,Liu P,Liu ZS,Liu QY

更新日期：2017-10-19 00:00:00

abstract：BACKGROUND:Hepatoblastoma (HB) is a common liver malignancy in children. Our previous study has disclosed the crucial role of STAT3 (signal transducer and activator of transcription 3) in HB. AIM OF THE STUDY:Present study was designed to study the circular RNA (circRNA) STAT3 in HB. METHODS:Gel electrophoresis revea...

journal_title：Journal of experimental & clinical cancer research : CR

authors： Liu Y,Song J,Liu Y,Zhou Z,Wang X

更新日期：2020-06-03 00:00:00

abstract：:The chemical modification of RNA is a newly discovered epigenetic regulation mechanism in cells and plays a crucial role in a variety of biological processes. N6-methyladenine (m6A) mRNA modification is the most abundant form of posttranscriptional RNA modification in eukaryotes. Through the development of m6A RNA seq...

journal_title：Journal of experimental & clinical cancer research : CR

authors： Zhang Y,Geng X,Li Q,Xu J,Tan Y,Xiao M,Song J,Liu F,Fang C,Wang H

更新日期：2020-09-17 00:00:00

abstract：:A 41-year-old white homosexual man presented with epigastric pain and jaundice. Physical examination showed enlargement of bilateral axillar and left inguinal lymph node, while ERCP and a CT scan suggested interruption of bile flow in the intrapancreatic tract of the common bile duct. An endoprosthesis was positioned ...

journal_title：Journal of experimental & clinical cancer research : CR

authors： De Toma G,Codacci-Pisanelli M,Nicolanti V,Plocco M,Caterino S,Perno CF

更新日期：1999-12-01 00:00:00

abstract：BACKGROUND:Dysregulation of transforming growth factor β (TGF-β) signaling and hypoxic microenvironment have respectively been reported to be involved in disease progression in malignancies of prostate. Emerging evidence indicates that downregulation of TGFBR2, a pivotal regulator of TGF-β signaling, may contribute to ...

journal_title：Journal of experimental & clinical cancer research : CR

authors： Zhou H,Wu G,Ma X,Xiao J,Yu G,Yang C,Xu N,Zhang B,Zhou J,Ye Z,Wang Z

更新日期：2018-04-27 00:00:00

abstract：BACKGROUND:Cell cycle checkpoint regulation is crucial for prevention of tumor in mammalian cells. Cyclin-dependant kinase 4 (CDK4) is important in cell cycle regulation, as it controls the G1-S phase of the cell cycle. CDK4 has potential mitogenic properties through phosphorylation of target proteins. We aimed at iden...

journal_title：Journal of experimental & clinical cancer research : CR

authors： Meenakshisundaram R,Gragnoli C

更新日期：2009-03-28 00:00:00

abstract：BACKGROUND:Clusterin is a cytoprotective chaperone protein involved in numerous physiological processes, carcinogenesis, tumor growth and tissue remodelling. The purpose of this study was to investigate whether clusterin (CLU), an antiapoptotic molecule, could be a potential predictor molecule for ovarian cancer and wh...

journal_title：Journal of experimental & clinical cancer research : CR

authors： Hassan MK,Watari H,Han Y,Mitamura T,Hosaka M,Wang L,Tanaka S,Sakuragi N

更新日期：2011-12-20 00:00:00

abstract：:Here we report the case of a patient with a soft tissue mass of the neck. For more than 10 years it was thought to be a branchial cyst and was later diagnosed to be a cystic lymph node metastasis from an occult thyroid carcinoma. ...

journal_title：Journal of experimental & clinical cancer research : CR

authors： Appetecchia M,Meçule A,Sciarretta F

更新日期：2002-03-01 00:00:00

abstract：BACKGROUND:An External Quality Assessment (EQA) program was developed to investigate the state of the art of HER2 immunohistochemical determination in breast cancer (BC) in 16 Pathology Departments in the Lazio Region (Italy). This program was implemented through two specific steps to evaluate HER2 staining (step 1) an...

journal_title：Journal of experimental & clinical cancer research : CR

authors： Terrenato I,Arena V,Pizzamiglio S,Pennacchia I,Perracchio L,Buglioni S,Ercolani C,Sperati F,Costarelli L,Bonanno E,Baldini D,Candia S,Crescenzi A,Dal Mas A,Di Cristofano C,Gomes V,Grillo LR,Pasquini P,Pericoli MN,Ra

更新日期：2013-08-21 00:00:00

abstract：BACKGROUND:Pancreatic cancer is a lethal disease in part because of its potential for aggressive invasion and metastasis. Lipoxin A4 (LXA4) is one of the metabolites that is derived from arachidonic acid and that is catalyzed by 15-lipoxygenase (15-LOX), and it has recently been reported to exhibit anti-cancer effects....

journal_title：Journal of experimental & clinical cancer research : CR

authors： Zong L,Chen K,Jiang Z,Chen X,Sun L,Ma J,Zhou C,Xu Q,Duan W,Han L,Lei J,Li X,Ma Q,Wang Z

更新日期：2017-12-11 00:00:00

abstract：BACKGROUND:Chemokine-like factor (CKLF)-like MARVEL transmembrane domain-containing family (CMTM) is a gene family involved in multiple malignancies. CMTM4 is a member of this family and is located at chromosome 16q22.1, a locus that harbours a number of tumour suppressor genes. It has been defined as a regulator of ce...

journal_title：Journal of experimental & clinical cancer research : CR

authors： Li T,Cheng Y,Wang P,Wang W,Hu F,Mo X,Lv H,Xu T,Han W

更新日期：2015-10-16 00:00:00

abstract：:The effect of malignant tumor growth on host's megakaryocytopoiesis and platelet production was studied in mice bearing transplantable Dalton's lymphoma. Tumor growth was paralleled by thrombocytosis, neutrophilia, and anemia. Platelet 51Cr half-life was normal but incorporation of 75Selenomethionine into circulating ...

journal_title：Journal of experimental & clinical cancer research : CR

authors： Ray MR

更新日期：2000-12-01 00:00:00

abstract：:The efficacy of currently developed methods for gene transfer into mammalian cells depends primarily on the transfection technique, and also on the type of targeted cells. Considering the importance of gene transfer in the creation of gene therapies, our study was aimed at the assessment of transfection capacity of re...

journal_title：Journal of experimental & clinical cancer research : CR

authors： Novaković S,Knezević M,Golouh R,Jezersek B

更新日期：1999-12-01 00:00:00