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Stem cells in clinical practice: applications and warnings.

Abstract：

UNLABELLED:Stem cells are a relevant source of information about cellular differentiation, molecular processes and tissue homeostasis, but also one of the most putative biological tools to treat degenerative diseases. This review focuses on human stem cells clinical and experimental applications. Our aim is to take a correct view of the available stem cell subtypes and their rational use in the medical area, with a specific focus on their therapeutic benefits and side effects. We have reviewed the main clinical trials dividing them basing on their clinical applications, and taking into account the ethical issue associated with the stem cell therapy. METHODS:We have searched Pubmed/Medline for clinical trials, involving the use of human stem cells, using the key words "stem cells" combined with the key words "transplantation", "pathology", "guidelines", "properties" and "risks". All the relevant clinical trials have been included. The results have been divided into different categories, basing on the way stem cells have been employed in different pathological conditions.

journal_name

J Exp Clin Cancer Res

journal_title

Journal of experimental & clinical cancer research : CR

authors

Lodi D,Iannitti T,Palmieri B

doi

10.1186/1756-9966-30-9

subject

Has Abstract

pub_date

2011-01-17 00:00:00

pages

9

eissn

0392-9078

issn

1756-9966

pii

1756-9966-30-9

journal_volume

30

pub_type

杂志文章,评审

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