Cardiovascular morbidity and the use of inhaled bronchodilators.

abstract：BACKGROUND:Prediction of future exacerbations of chronic obstructive pulmonary disease (COPD) is a major concern for long-term management of this disease. AIM:To determine which of three multidimensional assessment systems (the body mass index, obstruction, dyspnea, and exercise capacity [BODE] index; dyspnea, obstruc...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Motegi T,Jones RC,Ishii T,Hattori K,Kusunoki Y,Furutate R,Yamada K,Gemma A,Kida K

更新日期：2013-01-01 00:00:00

abstract：:Regenerative or stem cell therapy is an emerging field of treatment based on stimulation of endogenous resident stem cells or administration of exogenous stem cells to treat diseases or injury and to replace malfunctioning or damaged tissues. Current evidence suggests that in the lung, these cells may participate in t...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Lipsi R,Rogliani P,Calzetta L,Segreti A,Cazzola M

更新日期：2014-12-12 00:00:00

abstract：Introduction:Biomass smoke exposure (BSE) is a recognized cause of COPD particularly in rural areas. However, little research has been focused on BSE in suburban areas. Objective:The aim of this study was to determine the prevalence of COPD, respiratory symptoms (RS) and BSE in women living in a suburban area of Mexic...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Ramírez-Venegas A,Velázquez-Uncal M,Pérez-Hernández R,Guzmán-Bouilloud NE,Falfán-Valencia R,Mayar-Maya ME,Aranda-Chávez A,Sansores RH

更新日期：2018-05-25 00:00:00

abstract：INTRODUCTION:Pulmonary emphysema causes several electrocardiogram changes, and one of the most common and well known is on the frontal P-wave axis. P-axis verticalization (P-axis > 60°) serves as a quasidiagnostic indicator of emphysema. The correlation of P-axis verticalization with the radiological severity of emphys...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Chhabra L,Chaubey VK,Kothagundla C,Bajaj R,Kaul S,Spodick DH

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:In patients with acute hypercapnic respiratory failure (AHRF) during exacerbations of COPD, mortality can be high despite noninvasive ventilation (NIV). For some, AHRF is terminal and NIV is inappropriate. However there is no definitive method of identifying patients who are unlikely to survive. The aim of t...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Haja Mydin H,Murphy S,Clague H,Sridharan K,Taylor IK

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Alpha-1-antitrypsin deficiency (AATD) is associated with a high risk for the development of early-onset emphysema and liver disease. A large majority of subjects with severe AATD carry the ZZ genotype, which can be easily detected. Another rare pathologic variant, the Mmalton allele, causes a ...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Belmonte I,Barrecheguren M,López-Martínez RM,Esquinas C,Rodríguez E,Miravitlles M,Rodríguez-Frías F

更新日期：2016-10-11 00:00:00

abstract：:COPD is uniquely situated as a chronic disease at the beginning of the 21st century; it is not only an established major cause of mortality and morbidity but is increasing in prevalence despite current medical interventions. In addition COPD is not a stable disease but its natural history is punctuated by periods of a...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Wilkinson T,Wedzicha JA

更新日期：2006-01-01 00:00:00

abstract：BACKGROUND:The clinical efficacy and safety of a mometasone furoate/formoterol fumarate (MF/F) fixed-dose combination formulation administered via a metered-dose inhaler was investigated in patients with moderate to very severe chronic obstructive pulmonary disease (COPD). METHODS:Two 52-week, multicenter, double-blin...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Tashkin DP,Doherty DE,Kerwin E,Matiz-Bueno CE,Knorr B,Shekar T,Gates D,Staudinger H

更新日期：2012-01-01 00:00:00

abstract：:Bronchoconstriction has been reported in asthma and chronic obstructive pulmonary disease (COPD) patients after administration of some aqueous inhalation solutions. We investigated the incidence of this event during long-term clinical trials of tiotropium delivered via Respimat(®) Soft Mist™ Inhaler (SMI). We retrospe...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Hodder R,Pavia D,Lee A,Bateman E

更新日期：2011-01-01 00:00:00

abstract：Background:Patients with chronic obstructive pulmonary disease (COPD) and cardiovascular comorbidities may have an increased risk of medication-related cardiac arrhythmias. We therefore performed an analysis of Holter electrocardiogram (ECG) data from two large, long-term, controlled clinical COPD trials to investigate...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Andreas S,Bothner U,de la Hoz A,Kloer I,Trampisch M,Alter P

更新日期：2020-08-10 00:00:00

abstract：:Background: There are currently limited real-world data on the clinical burden of illness in patients with COPD who continue to exacerbate despite receiving triple therapy. The aim of this study was to compare the burden of COPD in patients with and without a phenotype characterized by a high blood eosinophil count an...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Müllerová H,Meeraus WH,Galkin DV,Albers FC,Landis SH

更新日期：2019-03-28 00:00:00

abstract：:A number of excellent intervention studies related to clinical and psychosocial aspects of chronic obstructive pulmonary disease (COPD) have been undertaken in the recent past. A range of outcomes have been examined including pulmonary function, health care use, quality of life, anxiety and depression, ambulation, exe...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Clark NM,Dodge JA,Partridge MR,Martinez FJ

更新日期：2009-01-01 00:00:00

abstract：Objective:Chronic obstructive pulmonary disease (COPD) is associated with atherosclerosis. Previous studies including limited sample sizes have shown the prevalence of peripheral arterial occlusive disease (PAOD) among COPD patients. We sought to investigate the incidence of PAOD among COPD patients in Taiwan using a n...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Liao KM,Kuo LT,Lu HY

更新日期：2019-07-04 00:00:00

abstract：Background:Chronic obstructive pulmonary disease (COPD) is prevalent and poses a heavy burden worldwide. However, patients know little about COPD, and primary health care providers have poor therapy capability in China. Enjoying Breathing Program aims to establish a new comprehensive COPD patient management system, inc...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Jia C,Zhang C,Fang F,Huang K,Dong F,Gu X,Niu H,Li S,Wang C,Yang T

更新日期：2020-09-15 00:00:00

abstract：Purpose:Previous studies have described the incidence, risk factors, and outcomes for patients with acute exacerbations of COPD (AECOPD) developing acute kidney injury (AKI). However, little is known about the differences between community-acquired AKI (CA-AKI) and hospital-acquired AKI (HA-AKI) in patients with AECOPD...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Cao CC,Chen DW,Li J,Ma MQ,Chen YB,Cao YZ,Hua X,Shao W,Wan X

更新日期：2018-07-17 00:00:00

abstract：:Backgroud and objectives: Although lung attenuation distribution and lung volume on computed tomography (CT) have been widely used in evaluating COPD and interstitial lung disease, there are only a few studies regarding the normal range of these indices, especially in Chinese subjects. We aimed to describe the normal ...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Cheng T,Li Y,Pang S,Wan H,Shi G,Cheng Q,Li Q,Pan Z,Huang S

更新日期：2019-07-24 00:00:00

abstract：Rationale:Acute exacerbations of chronic obstructive pulmonary disease (AECOPD) are caused by a variety of different etiologic agents. Our aim was to phenotype COPD exacerbations using imaging (chest X-ray [CXR] and computed tomography [CT]) and to determine the possible role of the blood tests (C-reactive protein [CRP...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Alotaibi NM,Chen V,Hollander Z,Hague CJ,Murphy DT,Leipsic JA,DeMarco ML,FitzGerald JM,McManus BM,Ng RT,Sin DD

更新日期：2018-01-08 00:00:00

abstract：BACKGROUND:Nowadays, there is increasing awareness about the frequent chronic comorbidities in patients with chronic obstructive pulmonary disease (COPD) but little information is available to quantify the burden of illness that these conditions cause in this population. We aimed to identify and describe a population s...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Anecchino C,Rossi E,Fanizza C,De Rosa M,Tognoni G,Romero M,working group ARNO project.

更新日期：2007-01-01 00:00:00

abstract：BACKGROUND:indacaterol is a novel, inhaled once-daily ultra-long-acting β(2)-agonist for the treatment of chronic obstructive pulmonary disease (COPD). OBJECTIVES:this study compared the onset of action of single doses of indacaterol 150 and 300 μg with salbutamol 200 μg, salmeterol-fluticasone 50/500 μg, and placebo ...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Balint B,Watz H,Amos C,Owen R,Higgins M,Kramer B,INSURE Study Investigators.

更新日期：2010-09-07 00:00:00

abstract：Purpose:Patients with COPD might be particularly susceptible to hypoxia-induced autonomic dysregulation. Decreased baroreflex sensitivity (BRS) and increased blood pressure (BP) variability (BPV) are markers of impaired cardiovascular autonomic regulation and there is evidence for an association between decreased BRS/i...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Schwarz EI,Latshang TD,Furian M,Flück D,Segitz S,Müller-Mottet S,Ulrich S,Bloch KE,Kohler M

更新日期：2019-03-14 00:00:00

abstract：Purpose:This study compared the effects of inpatient-based rehabilitation program of patients with chronic obstructive pulmonary disease (COPD) using non-immersive virtual reality (VR) training with a traditional pulmonary rehabilitation program. The aims of this study were to determine 1) whether rehabilitation featur...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Rutkowski S,Rutkowska A,Kiper P,Jastrzebski D,Racheniuk H,Turolla A,Szczegielniak J,Casaburi R

更新日期：2020-01-13 00:00:00

abstract：:Abstract: Static lung hyperinflation has important clinical consequences in patients with chronic obstructive pulmonary disease (COPD). Given that most of these patients have respiratory and peripheral muscle weakness, dyspnea and functional exercise capacity may improve as a result of inspiratory muscle training (IMT...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Shahin B,Germain M,Kazem A,Annat G

更新日期：2008-01-01 00:00:00

abstract：Background:Few studies have examined changes in the pain experience of patients with COPD and predictors of pain in these patients. Objectives:The objectives of the study were to examine whether distinct groups of COPD patients could be identified based on changes in the occurrence and severity of pain over 12 months ...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Bentsen SB,Miaskowski C,Cooper BA,Christensen VL,Henriksen AH,Holm AM,Rustøen T

更新日期：2018-03-06 00:00:00

abstract：:Chronic obstructive pulmonary disease (COPD) is a major cause of morbidity and mortality. Current therapies confer partial benefits either by incompletely improving airflow limitation or by reducing acute exacerbations, hence new therapies are desirable. In the absence of robust early predictors of clinical efficacy, ...

journal_title：International journal of chronic obstructive pulmonary disease

authors： van der Merwe R,Molfino NA

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND:Limited mobility is a risk factor for developing chronic obstructive pulmonary disease (COPD)-related disabilities. Little is known about the validity of the Short Physical Performance Battery (SPPB) for identifying mobility limitations in patients with COPD. OBJECTIVE:To determine the clinical validity of ...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Bernabeu-Mora R,Medina-Mirapeix F,Llamazares-Herrán E,García-Guillamón G,Giménez-Giménez LM,Sánchez-Nieto JM

更新日期：2015-12-03 00:00:00

abstract：BACKGROUND:Little is known regarding the relationship between balance impairments and physical activity in COPD. There has been no study investigating the relationship between balance and objectively measured physical activity. Here we investigated the association between balance and physical activity measured by an ac...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Iwakura M,Okura K,Shibata K,Kawagoshi A,Sugawara K,Takahashi H,Shioya T

更新日期：2016-07-01 00:00:00

abstract：Purpose:Primary care COPD guidelines indicate that COPD patients with asthma characteristics should be treated as having asthma. This study aims to describe the prevalence of asthma characteristics in patients with a pulmonologist-confirmed working diagnosis of COPD or ACO. Patients and Methods:This retrospective cros...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Baron AJ,Flokstra-de Blok BMJ,van Heijst E,Riemersma RA,Sonnenschein-van der Voort AMM,Metting EI,Kocks JWH

更新日期：2020-07-06 00:00:00

abstract：Rationale:COPD has been perceived as being a disease of older men. However, >7 million women are estimated to live with COPD in the USA alone. Despite a growing body of literature suggesting an increasing burden of COPD in women, the evidence is limited. Objectives:To assess and synthesize the available evidence among...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Ntritsos G,Franek J,Belbasis L,Christou MA,Markozannes G,Altman P,Fogel R,Sayre T,Ntzani EE,Evangelou E

更新日期：2018-05-10 00:00:00

abstract：:Pulmonary emphysema is characterized by the irreversible loss of pulmonary alveoli. Despite recent advances in the understanding this disease, its treatment remains palliative. In this review, we will successively review the data suggesting (1) that alveolar regeneration systems are functional in the mammalian lung an...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Plantier L,Boczkowski J,Crestani B

更新日期：2007-01-01 00:00:00

abstract：BACKGROUND:The syndrome of combined pulmonary fibrosis and emphysema (CPFE) is a recently described entity associating upper-lobe emphysema and lower-lobe fibrosis. We sought to evaluate differences in pulmonary function between CPFE patients with and without airflow obstruction. SUBJECTS AND METHODS:Thirty-one CPFE p...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Kitaguchi Y,Fujimoto K,Hanaoka M,Honda T,Hotta J,Hirayama J

更新日期：2014-07-29 00:00:00