Circumferential and axial distribution of esophageal mucosal damage in reflux disease.

abstract：:Gamma-glutamyltransferase (GGT) is a membrane-bound enzyme involved in the glutathione metabolism. Studies suggested that GGT was a marker of apoptotic balance and modulated tumor progression, invasion and drug resistance. Recently, GGT was shown to be associated with the progression of high-grade esophageal epithelia...

journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

authors： Yang F,Zhang S,Yang H,Luo K,Wen J,Hu Y,Hu R,Huang Q,Chen J,Fu J

更新日期：2015-07-01 00:00:00

abstract：:The survival advantage associated with the addition of surgical therapy in esophageal squamous cell carcinoma (ESCC) patients who demonstrate a complete clinical response to chemoradiotherapy is unclear, and many institutions have adopted an organ-preserving strategy of selective surgery in this population. We sought ...

journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

authors： Mitchell KG,Nelson DB,Corsini EM,Vaporciyan AA,Antonoff MB,Mehran RJ,Rice DC,Roth JA,Sepesi B,Walsh GL,Bhutani MS,Maru DM,Wu CC,Nguyen QN,Ajani JA,Swisher SG,Hofstetter WL

更新日期：2020-03-16 00:00:00

abstract：:Animal models of Barrett's metaplasia and esophageal adenocarcinoma are important to further characterize the disease and test potential therapies. This paper reviews the development of the surgical model of esophageal adenocarcinoma in the rat and considers whether this model provides a biologically accurate represen...

journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

authors： Hindmarsh A,Belshaw N,Mehta S,Johnson IT,Rhodes M

更新日期：2012-02-01 00:00:00

abstract：:Barrett's esophagus (BE) is a chronic complication associated with gastroesophageal reflux disease. The ICD-9-CM code used for BE, 530.2, is also used for patients with 'ulcer of the esophagus.' We aimed to determine if the ICD-9-CM code of 530.2 is reliable for identifying cases of Barrett's esophagus within database...

journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

authors： Jacobson BC,Gerson LB

更新日期：2008-01-01 00:00:00

abstract：:This study looks at toxicity and survival data when chemoradiation (CRT) is delivered using intensity-modulated radiation therapy (IMRT) after induction chemotherapy. Forty-one patients with esophageal adenocarcinoma treated with IMRT from March 2007 to May 2009 at Memorial Sloan-Kettering Cancer Center were analyzed....

journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

authors： Gerber N,Ilson DH,Wu AJ,Janjigian YY,Kelsen DP,Zheng J,Zhang Z,Bains MS,Rizk N,Rusch VW,Goodman KA

更新日期：2014-04-01 00:00:00

abstract：:The cancer stem cell theory states that cancers contain tumor-forming cells that have the ability to self-renew as well as give rise to cells that differentiate. Cancer stem cells have been identified in several solid tumors, but stem cells in normal human esophagus or in Barrett's esophagus or adenocarcinoma have not...

journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

authors： Bobryshev YV,Freeman AK,Botelho NK,Tran D,Levert-Mignon AJ,Lord RV

更新日期：2010-09-01 00:00:00

abstract：:Endoscopy can be used to monitor the onset of metaplastic transformation and to observe the progression of neoplasia in small animal models of Barrett's esophagus. By avoiding animal sacrifice, the natural history of this disease can be studied in a longitudinal fashion. We aim to characterize the endoscopic features ...

journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

authors： Lu S,Lowe AW,Triadafilopoulos G,Hsiung PL,Hao Y,Crawford JM,Wang TD

更新日期：2009-01-01 00:00:00

abstract：:Transnasal ultrathin esophagogastroduodenoscopy (N-EGD) with less gagging reflexes under non-sedation is likely suitable for the diagnosis of gastroesophageal reflux disease (GERD), however, N-EGD might have drawbacks, including its low image resolution. Limited information is available regarding the diagnosability of...

journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

authors： Mori A,Ohashi N,Yoshida A,Nozaki M,Tatebe H,Okuno M,Hoshihara Y,Hongo M

更新日期：2011-02-01 00:00:00

abstract：:The high-resolution microendoscope (HRME) is a novel imaging modality that may be useful in the surveillance of Barrett's esophagus in low-resource or community-based settings. In order to assess accuracy and interrater reliability of microendoscopists in identifying Barrett's-associated neoplasia using HRME images, w...

journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

authors： Vila PM,Kingsley MJ,Polydorides AD,Protano MA,Pierce MC,Sauk J,Kim MK,Patel K,Godbold JH,Waye JD,Richards-Kortum R,Anandasabapathy S

更新日期：2014-01-01 00:00:00

abstract：:The aim of this study was to evaluate the effectiveness of floppy Nissen fundoplication with intraoperative esophageal manometry. Between February 1992 and July 2004, there were 102 patients with sliding hiatal hernia undergoing transabdominal Nissen fundoplication. They were divided into three groups: 27 patients wer...

journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

authors： Lei Y,Li JY,Jiang J,Wang J,Zhang QY,Wang TY,Krasna MJ

更新日期：2008-01-01 00:00:00

abstract：:Barrett's esophagus, the management of which remains controversial, is the precursor condition to esophageal adenocarcinoma. A number of endoscopic treatments have been designed as an alternative to surgical resection for patients with high-grade dysplasia. One of these, photodynamic therapy, involves the light activa...

journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

authors： Sánchez A,Reza M,Blasco JA,Callejo D

更新日期：2010-11-01 00:00:00

abstract：:In a series of 378 patients with esophageal carcinoma, 43 patients with head and neck carcinoma were divided into two groups: 30 patients without symptoms whose esophageal or head and neck second primary carcinomas were incidentally detected by an endoscopic examination for the second carcinoma (group 1) and 13 patien...

journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

authors： Murakami S,Hashimoto T,Noguchi T,Hazamada S,Uchida Y,Suzuki M,Yanagisawa S

更新日期：1999-01-01 00:00:00

abstract：:Routine esophageal manometry for surgical planning before laparoscopic paraesophageal hernia (PEH) has been advocated in an effort to reduce the likelihood of postoperative dysphagia. The purpose of this study is to investigate whether omitting routine preoperative esophageal manometry is associated with a change in t...

journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

authors： Zevin B,Jones EL,Martin Del Campo SE,Perry KA

更新日期：2017-07-01 00:00:00

abstract：:We reviewed 10 patients with esophageal mucosal carcinoma in order to improve the early diagnosis of the disease. Histologically seven of the 14 lesions were carcinomas in situ (epithelial cancer), and the other seven lesions were carcinomas confined to the mucosa other than epithelial cancer (muscularis mucosae cance...

journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

authors： Kimura H,Konishi K,Earashi M,Satou T,Nojima N,Inoue T,Maeda K,Yabushita K,Kuroda Y,Tsuji M,Miwa A

更新日期：1997-07-01 00:00:00

abstract：:We report analytic and consensus processes that produced recommendations for neoadjuvant pathologic stage groups (ypTNM) of esophageal and esophagogastric junction cancer for the AJCC/UICC cancer staging manuals, 8th edition. The Worldwide Esophageal Cancer Collaboration provided data for 22,654 patients with epitheli...

journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

authors： Rice TW,Ishwaran H,Kelsen DP,Hofstetter WL,Apperson-Hansen C,Blackstone EH,Worldwide Esophageal Cancer Collaboration Investigators.

更新日期：2016-11-01 00:00:00

abstract：:Combined modality treatment for esophageal carcinoma seems to improve survival over surgery alone. Different combinations of cytotoxic drugs have been studied to improve antitumor efficacy and limit the toxicity of chemoradiotherapy (CRT) with inconsistent results. We present a prospective study of neoadjuvant CRT wit...

journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

authors： Zemanova M,Petruzelka L,Pazdro A,Kralova D,Smejkal M,Pazdrova G,Honova H

更新日期：2010-02-01 00:00:00

abstract：:It is still controversial whether adjuvant chemotherapy of cisplatin, 5-fluorouracil and leucovorin can increase the overall survival of esophageal cancer patients, and which subgroup of patients get most benefits from it. Between 1998 and 2004, 66 esophageal cancer patients with adjuvant chemotherapy and 160 well-mat...

journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

authors： Zhang J,Zhang YW,Chen ZW,Zhou XY,Lu S,Luo QQ,Hu H,Miao LS,Ma LF,Xiang JQ

更新日期：2008-01-01 00:00:00

abstract：:Gastroesophageal reflux disease is caused predominantly by lower esophageal sphincter insufficiency. Reports suggest that it is possible to distinguish between two main mechanisms causing reflux: low basal sphincter pressure leading to free reflux, mostly occurring at night in the supine position, and increased transi...

journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

authors： Meining A,Fackler A,Tzavella K,Storr M,Allescher HD,Klauser A,Heldwein W

更新日期：2004-01-01 00:00:00

abstract：:This study assessed the clinical value of CYFRA 21-1 in comparison with squamous cell carcinoma antigen (SCC-Ag), carcinoembryonic antigen (CEA), and carbohydrate antigen 19-9 (CA19-9) in patients with esophageal squamous cell carcinoma. In 112 primary cancer patients, the diagnostic sensitivity of CYFRA 21-1 (33.9%) ...

journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

authors： Nakamura T,Ide H,Eguchi R,Hayashi K,Takasaki K,Watanabe S

更新日期：2017-11-01 00:00:00

abstract：:Barrett's esophagus (BE) is the strongest risk factor for the development of esophageal adenocarcinoma. However, the risk of cancer progression is difficult to ascertain in individuals, as a significant number of patients with BE do not necessarily progress to esophageal adenocarcinoma. There are several issues with t...

journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

authors： Timmer MR,Sun G,Gorospe EC,Leggett CL,Lutzke L,Krishnadath KK,Wang KK

更新日期：2013-08-01 00:00:00

abstract：:Fifty-two patients presenting with upper or middle esophageal carcinoma after gastrectomy between 1980 and 2003 were analyzed retrospectively. Among them, there were five cases of total gastrectomy, six cases of proximal partial gastrectomy and 41 cases of distal subtotal gastrectomy. The interval between gastrectomy ...

journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

authors： Cheng BC,Xia J,Shao K,Mao ZF,Huang J,Wang TS

更新日期：2005-01-01 00:00:00

abstract：:Published guidelines for the management of eosinophilic esophagitis (EoE) recommend an initial trial of proton pump inhibitors (PPI), histologic assessment for response to therapy, and tailoring treatments to patient needs and provider resources. Effectiveness studies directly comparing therapies are lacking, leaving ...

journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

authors： Chang JW,Saini SD,Mellinger JL,Chen JW,Zikmund-Fisher BJ,Rubenstein JH

更新日期：2019-06-01 00:00:00

abstract：:Apolipoprotein E (ApoE) is the most well-described genetic risk factor for Alzheimer's disease and nonpathological cognitive decline. While possession of the E2 allele may have protective properties, substantial research evidence suggests the E4 allele increases the risk of cognitive degeneration. As neurodegenerative...

journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

authors： Mentz H,Horan M,Payton A,Ollier W,Pendleton N,Hamdy S

更新日期：2015-01-01 00:00:00

abstract：:Dysplasia and esophageal adenocarcinoma may arise in patients with Barrett's esophagus after fundoplication esophageal pH monitoring showing no acid in esophagus. This suggests the need to develop methodology to evaluate the occurrence of ultra-distal reflux (1cm above the LES). The objective of the study was to compa...

journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

authors： Seguro FC,Santo MA,Szachnowicz S,Maluf Filho F,Kishi HS,Falcão AM,Nasi A,Sallum RA,Cecconello I

更新日期：2011-08-01 00:00:00

abstract：:We retrospectively investigated the efficacy of a chemoradiotherapy regimen using daily low-dose cisplatin and continuous 5-fluorouracil infusion in 71 registered patients with unresectable esophageal cancer. The overall response rate (complete response plus partial response) was 59%. The major toxicities observed wer...

journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

authors： Takagawa R,Kunisaki C,Makino H,Kosaka T,Ono HA,Akiyama H,Shimada H

更新日期：2009-01-01 00:00:00

abstract：:Barrett's esophagus (BE), a premalignant condition for the development of esophageal adenocarcinoma (EAC), is a consequence of chronic gastroesophageal reflux disease (GERD). Although the incidence of EAC is increasing, a similar trend for BE is not clear. We aimed to evaluate the prevalence of newly diagnosed BE over...

journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

authors： Hamade N,Weng G,Desai M,Chandrasekar VT,Dasari C,Kennedy K,Sharma P

更新日期：2021-01-16 00:00:00

abstract：:We studied the premalignant nature of achalasia using anti-Ki-67 and anti-p53 monoclonal antibodies immunohistochemically. In this study, four patients with esophageal carcinoma and achalasia were investigated. Three tumors were pT4 (UICC pTNM) and one tumor was pT1. The majority of non-malignant esophageal epithelium...

journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

authors： Fujii T,Yamana H,Sueyoshi S,Fujita H,Tanaka Y,Kubota M,Toh U,Mine T,Sasahara H,Shirouzu K,Kato S,Morimatsu M

更新日期：2000-01-01 00:00:00

abstract：:Chagas' disease and idiopathic achalasia have similar esophageal manifestations such as absent or incomplete lower esophageal sphincter relaxation and aperistalsis in the esophageal body (alterations seen mainly in the distal esophageal body). Our aim in this paper was to study the response of the proximal esophageal ...

journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

authors： Ramos RI,Varrica LM,Dantas RO

更新日期：2006-01-01 00:00:00

abstract：:The progression of certain primary esophageal motor disorders to achalasia has been documented; however, the true incidence of this decay is still elusive. This study aims to evaluate: (i) the incidence of the progression of diffuse esophageal spasm to achalasia, and (ii) predictive factors to this progression. Thirty...

journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

authors： Fontes LH,Herbella FA,Rodriguez TN,Trivino T,Farah JF

更新日期：2013-07-01 00:00:00

abstract：:Self-expanding metal stents (SEMS) are used to treat obstructive malignancies of the esophagus or esophagogastric junction; however, a potential complication is recurrent dysphagia because of tissue in/overgrowth. The placement of a second SEMS is one strategy to re-establish patency of the esophageal lumen. We evalua...

journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

authors： Conio M,Blanchi S,Filiberti R,De Ceglie A

更新日期：2010-09-01 00:00:00