Can the rat be used as a valid model of human esophageal adenocarcinoma?

abstract：:Lung and esophageal dysfunction are common in patients with connective tissue disease (CTD). Recent reports have suggested a link between pathologic gastroesophageal reflux and bronchiolitis obliterans syndrome (BOS) after lung transplant. Because patients with CTD have a high incidence of esophageal dysmotility and r...

journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

authors： Gasper WJ,Sweet MP,Golden JA,Hoopes C,Leard LE,Kleinhenz ME,Hays SR,Patti MG

更新日期：2008-01-01 00:00:00

abstract：:Gastroesophageal reflux disease is caused predominantly by lower esophageal sphincter insufficiency. Reports suggest that it is possible to distinguish between two main mechanisms causing reflux: low basal sphincter pressure leading to free reflux, mostly occurring at night in the supine position, and increased transi...

journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

authors： Meining A,Fackler A,Tzavella K,Storr M,Allescher HD,Klauser A,Heldwein W

更新日期：2004-01-01 00:00:00

abstract：:Tracheo-bronchial lesions with air leak are rare but a catastrophic complications of esophageal resections. We analyzed the management and outcome of 31 patients who developed a non-malignant lesion of the trachea or main stem bronchus after esophagectomy for esophageal cancer. All patients initially required endotrac...

journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

authors： Bartels HE,Stein HJ,Siewert JR

更新日期：1998-04-01 00:00:00

abstract：:Fas (CD95/Apo-1) receptor (FasR) is a cell-surface receptor that mediates apoptotic cell death upon triggering by Fas ligand (FasL). We sought to determine whether normal human esophageal epithelial cells express FasL and/or FasR and whether their localization is consistent with a role in the turnover of normal esopha...

journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

authors： Bennett MW,O'Connell J,O'Sullivan GC,Roche D,Brady C,Collins JK,Shanahan F

更新日期：1999-01-01 00:00:00

abstract：:Gamma-glutamyltransferase (GGT) is a membrane-bound enzyme involved in the glutathione metabolism. Studies suggested that GGT was a marker of apoptotic balance and modulated tumor progression, invasion and drug resistance. Recently, GGT was shown to be associated with the progression of high-grade esophageal epithelia...

journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

authors： Yang F,Zhang S,Yang H,Luo K,Wen J,Hu Y,Hu R,Huang Q,Chen J,Fu J

更新日期：2015-07-01 00:00:00

abstract：BACKGROUND:The COVID-19 pandemic continues to have a significant impact on the provision of medical care. Planning to ensure there is capability to treat those that become ill with the virus has led to an almost complete moratorium on elective work. This study evaluates the impact of COVID-19 on cancer, in particular s...

journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

authors： Wahed S,Chmelo J,Navidi M,Hayes N,Phillips AW,Immanuel A

更新日期：2020-09-04 00:00:00

abstract：:Human esophageal adenocarcinoma (EAC) cell lines have made a substantial contribution to elucidating mechanisms of carcinogenesis and drug discovery. Model research on EAC relies almost entirely on a relatively small set of established tumor cell lines because appropriate animal models are lacking. Nowadays, more than...

journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

authors： Boonstra JJ,Tilanus HW,Dinjens WN

更新日期：2015-01-01 00:00:00

abstract：:High body mass index (H-BMI; ≥25 kg/m(2) ) is common in US adults. In a small cohort of esophageal cancer (EC) patients treated with surgery, H-BMI and diagnosis of early stage EC appeared associated. We evaluated a much larger cohort of EC patients. From a prospectively maintained database, we analyzed 925 EC patient...

journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

authors： Hayashi Y,Correa AM,Hofstetter WL,Vaporciyan AA,Mehran RJ,Rice DC,Suzuki A,Lee JH,Bhutani MS,Welsh J,Lin SH,Maru DM,Swisher SG,Ajani JA

更新日期：2012-09-01 00:00:00

abstract：:We conducted a retrospective analysis to assess the toxicity and long-term survival of esophageal squamous cell carcinoma patients treated with three-dimensional conformal radiotherapy (3DCRT) or intensity-modulated radiotherapy (IMRT) versus conventional two-dimensional radiotherapy (2DRT). All data in the present st...

journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

authors： Deng JY,Wang C,Shi XH,Jiang GL,Wang Y,Liu Y,Zhao KL

更新日期：2016-11-01 00:00:00

abstract：:Surgically induced duodenal reflux results in cancer development in the rat esophagus. One proposed mechanism of carcinogenesis relies on the production of carcinogens in the presence of bacterial overgrowth. Against this background, intestinal microflora in the rat jejunum was analyzed before and after reflux-inducin...

journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

authors： Fein M,Fuchs KH,DeMeester TR,Peters JH,Wittmann D,Weig M

更新日期：2000-01-01 00:00:00

abstract：:While diagnostic overlap exists between gastroesophageal reflux disease and eosinophilic esophagitis especially on histological findings, therapeutic approaches for the two disease entities are very different. Recently, anti-inflammatory treatment, in addition to acid suppressants, has been investigated for gastroesop...

journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

authors： Lee H,Park JC,Shin SK,Lee SK,Lee YC

更新日期：2012-09-01 00:00:00

abstract：:Increasing experience with transhiatal esophagectomy (THE) has brought with it a good understanding of the advantages and disadvantages of the technique. As in our case, diaphragmatic hernias after THE may result from excess manipulation and extension of the hiatus during surgery. The varying nature of the clinical pr...

journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

authors： Hamaloglu E,Topaloglu S,Törer N

更新日期：2002-01-01 00:00:00

abstract：:There are limited data concerning the effects of 5-HT(1A) receptor activation on esophageal motility. Sumatriptan, a 5-HT(1A) receptor agonist, was recently reported to enhance esophageal peristalsis after intravenous administration. Buspirone, an orally available 5-HT(1A) receptor agonist, was shown to modulate gastr...

journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

authors： Di Stefano M,Papathanasopoulos A,Blondeau K,Vos R,Boecxstaens V,Farré R,Rommel N,Tack J

更新日期：2012-07-01 00:00:00

abstract：OBJECTIVE:Patient-reported outcome (PRO) measures are commonly used to capture patient experience with dysphagia and to evaluate treatment effectiveness. Inappropriate application can lead to distorted results in clinical studies. A systematic review of the literature on dysphagia-related PRO measures was performed to ...

journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

authors： Patel DA,Sharda R,Hovis KL,Nichols EE,Sathe N,Penson DF,Feurer ID,McPheeters ML,Vaezi MF,Francis DO

更新日期：2017-05-01 00:00:00

abstract：BACKGROUND AND AIMS:There has been a recent increase in the incidence of oropharyngeal cancer (OPC) associated with high-risk human papilloma virus (HPV) infection. We investigated the incidence of esophageal papilloma and the presence of high-risk HPV infection. METHODS:This is a cross-sectional study conducted at a ...

journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

authors： Pantham G,Ganesan S,Einstadter D,Jin G,Weinberg A,Fass R

更新日期：2017-01-01 00:00:00

abstract：:According to the Montreal Consensus Group's classification, gastroesophageal reflux disease develops when the reflux of stomach contents causes troublesome symptoms and/or complications such as esophagitis. The characteristic gastroesophageal reflux disease symptoms included in this statement are retrosternal burning ...

journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

authors： Sawaya RA,Macgill A,Parkman HP,Friedenberg FK

更新日期：2012-08-01 00:00:00

abstract：:Esophageal perforations carry a high potential for morbidity and mortality. The prognosis depends on rapid and precise diagnosis and management. Surgical site infections (SSIs) are very common following the surgical treatment of esophageal lesions. We aimed identify significant risk factors for SSI after surgery for e...

journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

authors： Breigeiron R,de Souza HP,Sidou JP

更新日期：2008-01-01 00:00:00

abstract：:The increasing incidence of adenocarcinoma of the lower esophagus and cardia arising in Barrett's metaplastic epithelium continues to be of great concern because medical and surgical efforts to reverse the process have been disappointing. A potential answer to the problem is removal of the metaplastic epithelium. Mode...

journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

authors： Bremner CG,Demeester TR

更新日期：2017-11-01 00:00:00

abstract：:The authors report a case of schistosomiasis of uncommon location. A patient submitted to esophagectomy for Chagas' megaesophagus was found to have eggs of Schistosoma mansoni upon pathologic examination of the surgical specimen. The authors discuss the anatomopathological aspects of schistosomiasis, as well as its oc...

journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

authors： Gagliardi D,Corsi PR,Eckley CA,Marigo C,Fava J

更新日期：1997-01-01 00:00:00

abstract：:The survival advantage associated with the addition of surgical therapy in esophageal squamous cell carcinoma (ESCC) patients who demonstrate a complete clinical response to chemoradiotherapy is unclear, and many institutions have adopted an organ-preserving strategy of selective surgery in this population. We sought ...

journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

authors： Mitchell KG,Nelson DB,Corsini EM,Vaporciyan AA,Antonoff MB,Mehran RJ,Rice DC,Roth JA,Sepesi B,Walsh GL,Bhutani MS,Maru DM,Wu CC,Nguyen QN,Ajani JA,Swisher SG,Hofstetter WL

更新日期：2020-03-16 00:00:00

abstract：:We performed a systematic review of epidemiological, diagnostic, and therapeutic outcomes of esophageal perforations. A systematic review was performed in PubMed database using the key-phrase 'esophageal perforation'. All studies regarding acute esophageal perforations were reviewed and parameters of epidemiology, dia...

journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

authors： Sdralis EIK,Petousis S,Rashid F,Lorenzi B,Charalabopoulos A

更新日期：2017-08-01 00:00:00

abstract：:The aim of this study was to determine the influence of splenectomy on perioperative morbidity and mortality, as well as on the long-term survival after esophageal resection for carcinoma of the esophagus. From September 1985 to July 2003, 404 patients underwent surgery for esophageal carcinoma in our institution. Spl...

journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

authors： Gockel I,Kneist W,Junginger T

更新日期：2005-01-01 00:00:00

abstract：:Muscularis externa of mouse esophagus is composed of two skeletal muscle layers in the adult. But less attention is paid to the histogenesis of the muscularis externa of the esophagus, and controversies still exist about the developmental process and the spatio-temporal expression characteristics of muscle-specific pr...

journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

authors： Cao XM,Yang YP,Li HR,Cui HL,Ya J

更新日期：2012-01-01 00:00:00

abstract：:Obesity increases the risk of gastroesophageal reflux disease (GERD). The majority of the reflux attacks occur postprandially. The influence of the speed of food intake on gastroesophageal reflux events is unclear in obese patients. To determine the influence of the speed of food intake on intraesophageal reflux event...

journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

authors： Bor S,Erdogan A,Bayrakci B,Yildirim E,Vardar R

更新日期：2017-01-01 00:00:00

abstract：:Totally minimally invasive Ivor-Lewis esophagectomy (Ivor Lewis TMIE) is a technically challenging procedure and is associated with a learning curve. Refinement of surgical technique is an important part of this learning curve. However, detailed descriptions of these refinements according to the idea, development, exp...

journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

authors： Stenstra MHBC,van Workum F,van den Wildenberg FJH,Polat F,Rosman C

更新日期：2019-03-01 00:00:00

abstract：:Published guidelines for the management of eosinophilic esophagitis (EoE) recommend an initial trial of proton pump inhibitors (PPI), histologic assessment for response to therapy, and tailoring treatments to patient needs and provider resources. Effectiveness studies directly comparing therapies are lacking, leaving ...

journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

authors： Chang JW,Saini SD,Mellinger JL,Chen JW,Zikmund-Fisher BJ,Rubenstein JH

更新日期：2019-06-01 00:00:00

abstract：SUMMARY:Failure to intubate and cross esophageal tumors by endosonography is reported in as many as 30% of cases and is thought to be associated with an especially poor prognosis. The aim of this study was to audit the above in a large consecutive case series of Endoscopic Ultrasound (EUS) examinations for esophageal c...

journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

authors： Morgan MA,Twine CP,Lewis WG,Lambe R,Oliphant HE,Robinson M,Crosby TD,Roberts SA

更新日期：2008-01-01 00:00:00

abstract：:Routine esophageal manometry for surgical planning before laparoscopic paraesophageal hernia (PEH) has been advocated in an effort to reduce the likelihood of postoperative dysphagia. The purpose of this study is to investigate whether omitting routine preoperative esophageal manometry is associated with a change in t...

journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

authors： Zevin B,Jones EL,Martin Del Campo SE,Perry KA

更新日期：2017-07-01 00:00:00

abstract：:Prevalence data for heartburn in the urban Black American community is lacking. In order to estimate prevalence for this community, we analyzed data from an ongoing cohort study in progress at our hospital. Comprehensive interviews allowed for exploration of factors associated with heartburn. Complex, stratified sampl...

journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

authors： Friedenberg FK,Makipour K,Palit A,Shah S,Vanar V,Richter JE

更新日期：2013-08-01 00:00:00

abstract：:A 73-year-old man had a low anterior resection for a villous adenoma in the rectosigmoid. On the 4th day after surgery, he suddenly developed severe interscapular pain. Aortic dissection was ruled out, but endoscopy showed black mucosa of the entire esophagus. With conservative treatment, including proton pump inhibit...

journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

authors： Reichart M,Busch OR,Bruno MJ,Van Lanschot JJ

更新日期：2000-01-01 00:00:00