Abstract：
:In a series of 378 patients with esophageal carcinoma, 43 patients with head and neck carcinoma were divided into two groups: 30 patients without symptoms whose esophageal or head and neck second primary carcinomas were incidentally detected by an endoscopic examination for the second carcinoma (group 1) and 13 patients with symptoms whose esophageal or head and neck second primary carcinomas were detected by routine examinations (group 2). Regarding the second primary carcinomas, the incidence of stage 0-I and curability were significantly higher in group 1 than in group 2 (p < 0.001 and p < 0.05 respectively). The 5-year overall survival rates of patients with the second primary carcinomas were significantly higher in group 1 (60.4%) than in group 2 (0%) (p < 0.01). We suggest that a routine endoscopic screening of the upper aerodigestive tract in patients with esophageal carcinoma or head and neck carcinoma contributes to the improvement of the prognosis and the patient's quality of life.
journal_name
Dis Esophagusjournal_title
Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagusauthors
Murakami S,Hashimoto T,Noguchi T,Hazamada S,Uchida Y,Suzuki M,Yanagisawa Sdoi
10.1046/j.1442-2050.1999.00045.xsubject
Has Abstractpub_date
1999-01-01 00:00:00pages
186-90issue
3eissn
1120-8694issn
1442-2050journal_volume
12pub_type
杂志文章abstract：:Positive proximal resection margins are strongly associated with anastomotic recurrence in esophageal cancer. However, the prognostic significance of dysplastic proximal resection margins remains unclear. The aim of this study is to investigate whether the dysplastic proximal resection margin can predict anastomotic r...
journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus
pub_type： 杂志文章
doi：10.1093/dote/doy090
更新日期：2019-05-01 00:00:00
abstract：:Placement of self-expanding metal stents (SEMS) for palliation of malignant stenoses at the gastroesophageal junction is often associated with stent migration and reflux symptoms. SEMS with an antireflux mechanism have been developed to overcome the latter problem. The aim of this study was to evaluate the safety and ...
journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus
pub_type： 临床试验,杂志文章
doi：10.1111/j.1442-2050.2007.00646.x
更新日期：2007-01-01 00:00:00
abstract：:We report a case of a patient with esophageal tuberculosis, a very uncommon form of extrapulmonar tuberculosis. Initially, because of constitutional symptomatology and radiological findings of mediastinal lymph node enlargement, lymphoma was considered. However, the endoscopic findings of ulcerative masses and a sinus...
journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus
pub_type： 杂志文章
doi：
更新日期：1998-01-01 00:00:00
abstract：:Perforations of the esophagus are uncommon complications of flexible gastrointestinal endoscopy. Perforations after endoscopy are likely to occur in the cervical esophagus, where fiber insertion is difficult anatomically. The diagnosis should be made as soon as possible, because mediastinitis and sepsis frequently dev...
journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus
pub_type： 杂志文章
doi：10.1046/j.1442-2050.2002.00253.x
更新日期：2002-01-01 00:00:00
abstract：SUMMARY:Failure to intubate and cross esophageal tumors by endosonography is reported in as many as 30% of cases and is thought to be associated with an especially poor prognosis. The aim of this study was to audit the above in a large consecutive case series of Endoscopic Ultrasound (EUS) examinations for esophageal c...
journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus
pub_type： 杂志文章
doi：10.1111/j.1442-2050.2008.00809.x
更新日期：2008-01-01 00:00:00
abstract：:Fas (CD95/Apo-1) receptor (FasR) is a cell-surface receptor that mediates apoptotic cell death upon triggering by Fas ligand (FasL). We sought to determine whether normal human esophageal epithelial cells express FasL and/or FasR and whether their localization is consistent with a role in the turnover of normal esopha...
journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus
pub_type： 杂志文章
doi：10.1046/j.1442-2050.1999.00032.x
更新日期：1999-01-01 00:00:00
abstract：:The laparoscopic Heller-Dor operation has been the procedure of choice for the treatment of achalasia. However, because the incidence of achalasia is low, reports on the outcome of surgical treatment for achalasia are limited. In this study, the therapeutic results after laparoscopic Heller-Dor operation for achalasia...
journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus
pub_type： 杂志文章
doi：10.1111/j.1442-2050.2008.00891.x
更新日期：2009-01-01 00:00:00
abstract：:Barrett's esophagus with high-grade dysplasia (BEHGD) and intramucosal esophageal adenocarcinoma (IMC) can be treated by radiofrequency ablation (RFA) and endoscopic mucosal resection (EMR). Efficacy of RFA and EMR in academic medical centers has been demonstrated in previous studies. However, the clinical effectivene...
journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus
pub_type： 杂志文章
doi：10.1093/dote/dox126
更新日期：2018-01-01 00:00:00
abstract：:We report the case of a 63-year-old man who presented with weakness, fatigue, dehydration, confusion, abdominal pain, congestive heart failure and hypercalcemia. He expired and autopsy revealed an exulcerating carcinoma of the esophagus, invading the esophageal wall and metastasizing to the lungs, skin and lymph nodes...
journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus
pub_type： 杂志文章
doi：10.1111/j.1442-2050.2003.00363.x
更新日期：2003-01-01 00:00:00
abstract：:Esophageal perforations carry a high potential for morbidity and mortality. The prognosis depends on rapid and precise diagnosis and management. Surgical site infections (SSIs) are very common following the surgical treatment of esophageal lesions. We aimed identify significant risk factors for SSI after surgery for e...
journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus
pub_type： 杂志文章
doi：10.1111/j.1442-2050.2007.00779.x
更新日期：2008-01-01 00:00:00
abstract：:A synergy exists between the psychological and physiological aspects of esophageal and other gastrointestinal symptoms. Based on a biopsychosocial model of disease, several multidisciplinary concepts of interventions in gastrointestinal disorders have been evaluated. The role of psychological factors in gastroesophage...
journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus
pub_type： 杂志文章,评审
doi：10.1046/j.1442-2050.2002.00261.x
更新日期：2002-01-01 00:00:00
abstract：:Routine esophageal manometry for surgical planning before laparoscopic paraesophageal hernia (PEH) has been advocated in an effort to reduce the likelihood of postoperative dysphagia. The purpose of this study is to investigate whether omitting routine preoperative esophageal manometry is associated with a change in t...
journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus
pub_type： 杂志文章
doi：10.1093/dote/dox044
更新日期：2017-07-01 00:00:00
abstract：OBJECTIVE:To determine the contribution of mechanical factors to the function of different types of fundoplication. DESIGN AND SETTING:An experimental bench-top study using abattoir-sourced pig esophagus and stomach placed on a tray. Preliminary esophageal myotomy ensured free reflux of 'intragastric fluid'. INTERVEN...
journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus
pub_type： 杂志文章
doi：10.1093/dote/10.2.110
更新日期：1997-04-01 00:00:00
abstract：:Gastric conduit used for reconstruction after esophagectomy for cancer has the potential to develop a metachronous neoplasm known as gastric tube cancer (GTC). The aim of this study was to review literature and evaluate outcomes and possible treatment strategies for GTC. A comprehensive systematic literature search wa...
journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus
pub_type： 杂志文章
doi：10.1093/dote/doz049
更新日期：2019-08-01 00:00:00
abstract：:Self-expanding metal stents (SEMS) are the treatment of choice for advanced esophageal cancers. Literature is scarce on risk factors predictors for adverse events after SEMS placement. Assess risk factors for adverse events after SEMS placement in advanced esophageal cancer and evaluate survival after SEMS placement. ...
journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus
pub_type： 杂志文章
doi：10.1111/dote.12467
更新日期：2017-02-01 00:00:00
abstract：:The distribution of lymph node metastases of adenocarcinomas of the gastroesophageal junction is classified into three types. The R0 resection with complete lymphadenectomy therefore requires different resection methods for type 1 and type 2/3 tumors. Comparing the subtotal esophagectomy and the extended gastrectomy, ...
journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus
pub_type： 杂志文章
doi：10.1046/j.1442-2050.2001.00167.x
更新日期：2001-01-01 00:00:00
abstract：:Nowadays esophageal squamous cell carcinoma (ESCC) is primarily treated by a comprehensive approach combining surgical resection and neoadjuvant chemo- or radiotherapy. However, ESCC is resistant to radiation therapy, resulting in its invasion, infiltration, and metastasis. It usually has rapidly progressed and has a ...
journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus
pub_type： 杂志文章
doi：10.1093/dote/dox027
更新日期：2017-06-01 00:00:00
abstract：:The increasing incidence of adenocarcinoma of the lower esophagus and cardia arising in Barrett's metaplastic epithelium continues to be of great concern because medical and surgical efforts to reverse the process have been disappointing. A potential answer to the problem is removal of the metaplastic epithelium. Mode...
journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus
pub_type：
doi：10.1093/dote/11.1.1
更新日期：2017-11-01 00:00:00
abstract：:Patients with Barrett's esophagus are at risk for dysplasia and esophageal adenocarcinoma. Although surgery was the mainstay treatment for Barrett's dysplasia and cancer, patients with high-grade dysplasia and early cancers now have several nonsurgical treatment options. Most of the endoscopic therapies are relatively...
journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus
pub_type： 杂志文章
doi：10.1111/j.1442-2050.2012.01411.x
更新日期：2013-04-01 00:00:00
abstract：:This study assessed the clinical value of CYFRA 21-1 in comparison with squamous cell carcinoma antigen (SCC-Ag), carcinoembryonic antigen (CEA), and carbohydrate antigen 19-9 (CA19-9) in patients with esophageal squamous cell carcinoma. In 112 primary cancer patients, the diagnostic sensitivity of CYFRA 21-1 (33.9%) ...
journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus
pub_type： 杂志文章
doi：
更新日期：1998-01-01 00:00:00
abstract：:Information is sparse and contradictory in the literature regarding the role of estrogen receptor (ER) and progesterone receptor (PR) in esophageal carcinoma. This study was conducted over a period of 18 months from September 2004 with the primary aim of determining the PR, ER alpha (ERalpha) and ER beta (ERbeta) stat...
journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus
pub_type： 杂志文章
doi：10.1111/j.1442-2050.2007.00767.x
更新日期：2008-01-01 00:00:00
abstract：:Esophageal perforation is an uncommon and challenging surgical emergency associated with high rates of morbidity and mortality. At present, no consensus exists on optimal management of the condition. The Pittsburgh Severity Score (PSS) is a tool intended to stratify perforation severity and guide treatment. However, t...
journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus
pub_type： 杂志文章
doi：10.1093/dote/doy109
更新日期：2019-02-01 00:00:00
abstract：:beta-Catenin, which is frequently overexpressed in a variety of human cancers including esophageal cancer, mediates cancer cell proliferation and tumor growth. In the present study, we used a human U6 promoter-driven DNA-template approach to induce short hairpin RNA (shRNA)-triggered RNA interference to silence beta-c...
journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus
pub_type： 杂志文章
doi：10.1111/j.1442-2050.2008.00875.x
更新日期：2009-01-01 00:00:00
abstract：:Endoscopic therapy (ablation +/- endoscopic resection) for high-grade dysplasia and/or intramucosal carcinoma (IMC) of the esophagus has demonstrated promising results. However, there is a concern that a curable, local disease may progress to systemic disease with repeated endotherapy. We performed a retrospective rev...
journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus
pub_type： 杂志文章
doi：10.1111/dote.12096
更新日期：2014-05-01 00:00:00
abstract：:The progression of certain primary esophageal motor disorders to achalasia has been documented; however, the true incidence of this decay is still elusive. This study aims to evaluate: (i) the incidence of the progression of diffuse esophageal spasm to achalasia, and (ii) predictive factors to this progression. Thirty...
journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus
pub_type： 杂志文章
doi：10.1111/j.1442-2050.2012.01377.x
更新日期：2013-07-01 00:00:00
abstract：:The objective of our study is to describe patient characteristics, clinical, endoscopic, and pathologic features and management of adult eosinophilic esophagitis (EE). A retrospective review of adults with EE (20 or more eosinophils per high-power field) diagnosed between 1997 and 2006, and a systematic review of the ...
journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus
pub_type： 杂志文章,评审
doi：10.1111/j.1442-2050.2007.00721.x
更新日期：2007-01-01 00:00:00
abstract：:Barrett's esophagus (BE) is a premalignant condition associated with the development of esophageal adenocarcinoma (EAC). Previous studies have implicated hydrophobic bile acids and gastric acid in BE and EAC pathogenesis. In this study, we tested the hypothesis that DNA damage, cytotoxicity and oxidative stress induce...
journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus
pub_type： 杂志文章
doi：10.1111/j.1442-2050.2009.00993.x
更新日期：2010-02-01 00:00:00
abstract：:It is essential to dissect an adequate number of lymph nodes (LNs) to ensure staging accuracy during esophagectomy with or without neoadjuvant therapy. We developed a statistical model to quantify the probability of precise nodal staging based on previous studies. Esophageal cancer patients who underwent esophagectomy...
journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus
pub_type： 杂志文章
doi：10.1093/dote/doz009
更新日期：2020-01-16 00:00:00
abstract：:The aim of this study was to evaluate the effectiveness of floppy Nissen fundoplication with intraoperative esophageal manometry. Between February 1992 and July 2004, there were 102 patients with sliding hiatal hernia undergoing transabdominal Nissen fundoplication. They were divided into three groups: 27 patients wer...
journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus
pub_type： 杂志文章
doi：10.1111/j.1442-2050.2007.00777.x
更新日期：2008-01-01 00:00:00
abstract：:We describe a technique that uses the internal mammary vessels to enhance long-segment jejunal graft blood supply in addition to an intact distal mesenteric vascular arcade. We believe that this technique, called vascular augmentation, improves jejunal graft perfusion and decreases ischemic complications. ...
journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus
pub_type： 杂志文章
doi：10.1046/j.1442-2050.2000.00118.x
更新日期：2000-01-01 00:00:00
