Comparison of anterior, posterior and total fundoplication using a viscera model.

Abstract:

OBJECTIVE:To determine the contribution of mechanical factors to the function of different types of fundoplication. DESIGN AND SETTING:An experimental bench-top study using abattoir-sourced pig esophagus and stomach placed on a tray. Preliminary esophageal myotomy ensured free reflux of 'intragastric fluid'. INTERVENTIONS:Anterior, posterior, and total fundoplications were performed on each of ten sets of viscera. MAIN OUTCOME MEASURES:Lower esophageal sphincter pressure was measured using a conventional esophageal manometry catheter. Intragastric pressure was measured with a single channel intragastric manometry catheter, whilst the stomach was inflated with coloured water. The maximum intragastric pressure or the pressure measured when the fundoplication yielded to gastric distension was recorded. RESULTS:All three types of fundoplication restored adequate competence to the gastroesophageal junction, although high-volume gastric infusions resulted in fundoplication yield in 4/10 anterior and 4/10 posterior fundoplications. Gastric distension resulted in fundal dilatation and consequent compression of the adjacent esophagus. Fundoplication generated a median rise of 11-13.5 mmHg in lower esophageal sphincter pressure, comparable to pressures reported in the postoperative clinical setting. Significantly greater intragastric volumes and pressures were tolerated following total fundoplication. CONCLUSIONS:This study suggests that mechanical factors could be major contributors to the ability of a fundoplication to restore gastroesophageal competence. Anterior, posterior and total fundoplications are all effective procedures.

journal_name

Dis Esophagus

authors

Watson DI,Mathew G,Pike GK,Jamieson GG

doi

10.1093/dote/10.2.110

subject

Has Abstract

pub_date

1997-04-01 00:00:00

pages

110-4

issue

2

eissn

1120-8694

issn

1442-2050

journal_volume

10

pub_type

杂志文章
  • S100A4 regulates motility and invasiveness of human esophageal squamous cell carcinoma through modulating the AKT/Slug signal pathway.

    abstract::The involvement of S100A4 in modulating invasiveness of esophageal squamous cell carcinoma (ESCC) cell lines was explored. It was shown that S100A4 expression is positively correlated with the degree of invasiveness in human ESCC cells. The S100A4-rich EC-1 cells displayed higher migratory and invasive cell behavior w...

    journal_title:Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

    pub_type: 杂志文章

    doi:10.1111/j.1442-2050.2012.01323.x

    authors: Zhang K,Zhang M,Zhao H,Yan B,Zhang D,Liang J

    更新日期:2012-11-01 00:00:00

  • Endoluminal methods of treating gastroesophageal reflux disease.

    abstract::Several endoluminal methods of treating gastroesophageal reflux disease (GERD) have either been approved, or are under investigation and development. This review outlines the two approved methods (Bard's endoluminal sewing machine and Curon's Stretta radiofrequency treatment), and describes the available data on new m...

    journal_title:Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

    pub_type: 杂志文章,评审

    doi:10.1046/j.1442-2050.2002.00242.x

    authors: Roy-Shapira A,Stein HJ,Scwartz D,Fich A,Sonnenschein E

    更新日期:2002-01-01 00:00:00

  • Targeted next-generation sequencing of commonly mutated genes in esophageal adenocarcinoma patients with long-term survival.

    abstract::Survival of patients with esophageal adenocarcinoma remains poor and individual differences in prognosis remain unexplained. This study investigated whether gene mutations can explain why patients with high-risk (pT3-4, pN+) esophageal adenocarcinoma survive past 5 years after esophagectomy. Six long-term survivors (L...

    journal_title:Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

    pub_type: 杂志文章

    doi:10.1093/dote/dox058

    authors: Visser E,Franken IA,Brosens LAA,de Leng WWJ,Strengman E,Offerhaus JA,Ruurda JP,van Hillegersberg R

    更新日期:2017-09-01 00:00:00

  • Proceedings from an international conference on ablation therapy for Barrett's mucosa: Brittany, France, 31 August - 2 September 1997.

    abstract::The increasing incidence of adenocarcinoma of the lower esophagus and cardia arising in Barrett's metaplastic epithelium continues to be of great concern because medical and surgical efforts to reverse the process have been disappointing. A potential answer to the problem is removal of the metaplastic epithelium. Mode...

    journal_title:Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

    pub_type:

    doi:10.1093/dote/11.1.1

    authors: Bremner CG,Demeester TR

    更新日期:2017-11-01 00:00:00

  • Jackhammer esophagus: high-resolution manometry and therapeutic approach using peroral endoscopic myotomy (POEM).

    abstract::We present the first report on peroral endoscopic myotomy (POEM) in the treatment of jackhammer esophagus. A 34-year-old female patient was newly diagnosed with a jackhammer esophagus. After failure of medical treatment, the patient underwent POEM procedure for myotomy of the spastic segment. Postoperatively, a mild e...

    journal_title:Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

    pub_type:

    doi:10.1111/dote.12182

    authors: Kandulski A,Fuchs KH,Weigt J,Malfertheiner P

    更新日期:2016-08-01 00:00:00

  • Primary esophageal mucosa-associated lymphoid tissue lymphoma diagnosed by using stacked forceps biopsy.

    abstract::Non-Hodgkin lymphoma involving the esophagus is very rare. Only a few cases have been reported in the English literature to date, and it accounts for less than 1% of all cases of gastrointestinal lymphoma. As this malignancy manifests as a submucosal tumor, pathological diagnosis by using a simple endoscopic biopsy al...

    journal_title:Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

    pub_type: 杂志文章,评审

    doi:10.1111/dote.12309

    authors: Lee DS,Ahn YC,Eom DW,Lee SJ

    更新日期:2016-10-01 00:00:00

  • Association of preoperative inflammation-based prognostic score with survival in patients undergoing salvage esophagectomy.

    abstract::Salvage esophagectomy (SALV) is potentially beneficial for patients with residual or relapsed esophageal carcinoma after definitive chemoradiotherapy (dCRT), although preoperatively identifying good candidates for SALV remains difficult. We investigated the prognostic impacts of inflammatory and nutritional status in ...

    journal_title:Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

    pub_type: 杂志文章

    doi:10.1093/dote/doy066

    authors: Sugawara K,Mori K,Yagi K,Aikou S,Uemura Y,Yamashita H,Seto Y

    更新日期:2019-04-01 00:00:00

  • Noncardiac chest pain: diagnostic evaluation.

    abstract::Noncardiac chest pain (NCCP) is a common and challenging clinical problem. It is estimated that more than 70 million Americans (23% of the population) suffer from this condition yearly. Patients with NCCP represent a diagnostic dilemma. Their chest pain is often indistinguishable from cardiac pain leading to extensive...

    journal_title:Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

    pub_type: 杂志文章,评审

    doi:10.1111/j.1442-2050.2011.01225.x

    authors: Fass R,Achem SR

    更新日期:2012-02-01 00:00:00

  • Voluntary and controlled weight loss can reduce symptoms and proton pump inhibitor use and dosage in patients with gastroesophageal reflux disease: a comparative study.

    abstract::A wide variety of pieces of evidence has suggested that obesity is associated with a significant increase in the risk for gastroesophageal reflux disease (GERD) symptoms and its complications. The aim of this study was to evaluate the effect of weight loss on reflux symptoms in overweight/obese patients with proven GE...

    journal_title:Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

    pub_type: 杂志文章

    doi:10.1111/dote.12319

    authors: de Bortoli N,Guidi G,Martinucci I,Savarino E,Imam H,Bertani L,Russo S,Franchi R,Macchia L,Furnari M,Ceccarelli L,Savarino V,Marchi S

    更新日期:2016-02-01 00:00:00

  • Fas ligand and Fas receptor are coexpressed in normal human esophageal epithelium: a potential mechanism of apoptotic epithelial turnover.

    abstract::Fas (CD95/Apo-1) receptor (FasR) is a cell-surface receptor that mediates apoptotic cell death upon triggering by Fas ligand (FasL). We sought to determine whether normal human esophageal epithelial cells express FasL and/or FasR and whether their localization is consistent with a role in the turnover of normal esopha...

    journal_title:Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

    pub_type: 杂志文章

    doi:10.1046/j.1442-2050.1999.00032.x

    authors: Bennett MW,O'Connell J,O'Sullivan GC,Roche D,Brady C,Collins JK,Shanahan F

    更新日期:1999-01-01 00:00:00

  • Treatment choices and outcomes of patients with manometrically diagnosed achalasia.

    abstract::This prospective population-based study was designed to evaluate treatment choices in patients with new manometrically diagnosed achalasia and their outcomes. Patients referred to the esophageal function laboratory were enrolled after a new manometric diagnosis of achalasia. Patients completed an initial achalasia sym...

    journal_title:Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

    pub_type: 杂志文章

    doi:10.1111/dote.12348

    authors: Yeung JC,Finley C,Hanna WC,Miller L,Ferri L,Urbach DR,Darling GE

    更新日期:2016-07-01 00:00:00

  • Bi-modality (chemo-radiation) versus tri-modality (chemo-radiation followed by surgery) treatment for carcinoma of the esophagus.

    abstract::The purpose of the study was to investigate the difference in overall survival in patients with localized carcinoma of esophagus treated using chemo-radiation (bi-modality, BM) or chemo-radiation followed by surgery (tri-modality, TM). From 1981 to 1999, 65 patients were identified who had localized carcinoma of the e...

    journal_title:Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

    pub_type: 杂志文章

    doi:10.1046/j.1442-2050.2001.00185.x

    authors: Chan R,Morrill S,Freeman D Jr,Colman M,Zwischenberger J

    更新日期:2001-01-01 00:00:00

  • Association of mu-opioid receptor expression with lymph node metastasis in esophageal squamous cell carcinoma.

    abstract::The mu-opioid receptor (MOR), a membrane-bound G protein-coupled receptor, is the main target for opioids in the nervous system. MOR1 has been found in several types of cancer cells and reported to be involved in tumor progression and metastasis. However, the expression and clinical significance of MOR1 in esophageal ...

    journal_title:Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

    pub_type: 杂志文章

    doi:10.1111/dote.12165

    authors: Zhang YF,Xu QX,Liao LD,Xu XE,Wu JY,Wu ZY,Shen JH,Li EM,Xu LY

    更新日期:2015-02-01 00:00:00

  • Diagnostic value of dilated intercellular space and histopathologic scores in gastroesophageal reflux disease.

    abstract::The aim of this paper is to investigate the diagnostic value of histopathologic score and the dilated intercellular space (DIS) in patients with gastroesophageal reflux disease (GERD) and functional heartburn (FH). Participants with GERD symptoms including reflux esophagitis, non-erosive reflux disease (NERD), Barrett...

    journal_title:Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

    pub_type: 杂志文章

    doi:10.1111/dote.12256

    authors: Cui R,Zhang H,Zhou L,Lu J,Xue Y,Wang Y,Yan X,Lin L,Lin S

    更新日期:2015-08-01 00:00:00

  • Morbidity following salvage esophagectomy for squamous cell carcinoma: the MD Anderson experience.

    abstract::The survival advantage associated with the addition of surgical therapy in esophageal squamous cell carcinoma (ESCC) patients who demonstrate a complete clinical response to chemoradiotherapy is unclear, and many institutions have adopted an organ-preserving strategy of selective surgery in this population. We sought ...

    journal_title:Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

    pub_type: 杂志文章

    doi:10.1093/dote/doz067

    authors: Mitchell KG,Nelson DB,Corsini EM,Vaporciyan AA,Antonoff MB,Mehran RJ,Rice DC,Roth JA,Sepesi B,Walsh GL,Bhutani MS,Maru DM,Wu CC,Nguyen QN,Ajani JA,Swisher SG,Hofstetter WL

    更新日期:2020-03-16 00:00:00

  • Patient characteristics, clinical, endoscopic, and histologic findings in adult eosinophilic esophagitis: a case series and systematic review of the medical literature.

    abstract::The objective of our study is to describe patient characteristics, clinical, endoscopic, and pathologic features and management of adult eosinophilic esophagitis (EE). A retrospective review of adults with EE (20 or more eosinophils per high-power field) diagnosed between 1997 and 2006, and a systematic review of the ...

    journal_title:Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

    pub_type: 杂志文章,评审

    doi:10.1111/j.1442-2050.2007.00721.x

    authors: Pasha SF,DiBaise JK,Kim HJ,De Petris G,Crowell MD,Fleischer DE,Sharma VK

    更新日期:2007-01-01 00:00:00

  • A structured training pathway to implement robot-assisted minimally invasive esophagectomy: the learning curve results from a high-volume center.

    abstract::To ensure safe implementation of robot-assisted minimally invasive esophagectomy (RAMIE), the learning process should be optimized. This study aimed to report the results of a surgeon who implemented RAMIE in a German high-volume center by following a tailored and structured training pathway that involved proctoring. ...

    journal_title:Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

    pub_type: 杂志文章

    doi:10.1093/dote/doaa047

    authors: Kingma BF,Hadzijusufovic E,Van der Sluis PC,Bano E,Lang H,Ruurda JP,Hillegersberg van R,Grimminger PP

    更新日期:2020-11-26 00:00:00

  • Adenocarcinoma in a gastric tube after esophagectomy for esophageal carcinoma.

    abstract::The development of an adenocarcinoma in a reconstructed tube after subtotal esophagectomy for esophagus squamous cell carcinoma (ESCC) is uncommon and has been reported in articles from the Japanese medical community. We report three cases of patients who had this clinical presentation. We suggest an approach to posto...

    journal_title:Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

    pub_type: 杂志文章

    doi:10.1046/j.1442-2050.2003.00317.x

    authors: Lamblin A,Mariette C,Triboulet JP

    更新日期:2003-01-01 00:00:00

  • Psychological and emotional aspects of gastroesophageal reflux disease.

    abstract::A synergy exists between the psychological and physiological aspects of esophageal and other gastrointestinal symptoms. Based on a biopsychosocial model of disease, several multidisciplinary concepts of interventions in gastrointestinal disorders have been evaluated. The role of psychological factors in gastroesophage...

    journal_title:Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

    pub_type: 杂志文章,评审

    doi:10.1046/j.1442-2050.2002.00261.x

    authors: Kamolz T,Velanovich V

    更新日期:2002-01-01 00:00:00

  • Prognostic significance of failure to cross esophageal tumors by endoluminal ultrasound.

    abstract:SUMMARY:Failure to intubate and cross esophageal tumors by endosonography is reported in as many as 30% of cases and is thought to be associated with an especially poor prognosis. The aim of this study was to audit the above in a large consecutive case series of Endoscopic Ultrasound (EUS) examinations for esophageal c...

    journal_title:Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

    pub_type: 杂志文章

    doi:10.1111/j.1442-2050.2008.00809.x

    authors: Morgan MA,Twine CP,Lewis WG,Lambe R,Oliphant HE,Robinson M,Crosby TD,Roberts SA

    更新日期:2008-01-01 00:00:00

  • Gastroesophageal reflux disease in obese patients: the role of obesity in management.

    abstract::Gastroesophageal reflux disease (GERD) is common in obese patients. The implications of obesity in the etiology, management and outcomes in treatment for GERD have become increasingly important due to an epidemic of obesity. The increasing prevalence of patients with both obesity and GERD merits evaluation of the appr...

    journal_title:Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

    pub_type: 杂志文章,评审

    doi:10.1111/j.1442-2050.2006.00540.x

    authors: Kendrick ML,Houghton SG

    更新日期:2006-01-01 00:00:00

  • Normal radiological lymph node appearance in the thorax.

    abstract::Modern treatment of esophageal cancer is multimodal and highly dependent on a detailed diagnostic assessment of clinical stage, which includes nodal stage. Clinical appraisal of nodal stage is highly dependent on knowledge of normal radiological appearance, information of which is scarce. We aimed to describe lymph no...

    journal_title:Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

    pub_type: 杂志文章

    doi:10.1093/dote/doy120

    authors: Hansen T,Nilsson M,Lindholm D,Sundström J,Hedberg J

    更新日期:2019-12-13 00:00:00

  • Trimodality therapy and definitive chemoradiotherapy for esophageal cancer: a single-center experience and review of the literature.

    abstract::In the UK, the standard of care for esophageal cancer has generally combined surgery with neoadjuvant chemotherapy, with definitive chemoradiotherapy (dCRT) being reserved for certain subgroups. Chemoradiotherapy followed by surgery (trimodality therapy) has not been widely adopted. The outcomes of patients undergoing...

    journal_title:Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

    pub_type: 杂志文章,评审

    doi:10.1111/dote.12242

    authors: Hategan M,Cook N,Prewett S,Hindmarsh A,Qian W,Gilligan D

    更新日期:2015-10-01 00:00:00

  • Endoscopic therapy for Barrett's high grade dysplasia and intramucosal esophageal cancer is effective in community clinical practice by advanced endoscopists following multidisciplinary approach.

    abstract::Barrett's esophagus with high-grade dysplasia (BEHGD) and intramucosal esophageal adenocarcinoma (IMC) can be treated by radiofrequency ablation (RFA) and endoscopic mucosal resection (EMR). Efficacy of RFA and EMR in academic medical centers has been demonstrated in previous studies. However, the clinical effectivene...

    journal_title:Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

    pub_type: 杂志文章

    doi:10.1093/dote/dox126

    authors: Al Natour RH,Catanzaro A,Zolotarevsky E,DeBenedet AT,Gunaratnam NT

    更新日期:2018-01-01 00:00:00

  • Relevant issues in tumor regression grading of histopathological response to neoadjuvant treatment in adenocarcinomas of the esophagus and gastroesophageal junction.

    abstract::Multimodality treatment combining surgery and oncologic treatment has become widely applied in curative treatment of esophageal and gastroesophageal junction adenocarcinoma. There is a need for a standardized tumor regression grade scoring system for clinically relevant effects of neoadjuvant treatment effects. There ...

    journal_title:Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

    pub_type: 杂志文章

    doi:10.1093/dote/doaa005

    authors: Klevebro F,Tsekrekos A,Low D,Lundell L,Vieth M,Detlefsen S

    更新日期:2020-06-15 00:00:00

  • Optical techniques for perfusion monitoring of the gastric tube after esophagectomy: a review of technologies and thresholds.

    abstract::Anastomotic leakage is one of the most severe complications after esophageal resection with gastric tube reconstruction. Impaired perfusion of the gastric fundus is seen as the main contributing factor for this complication. Optical modalities show potential in recognizing compromised perfusion in real time, when isch...

    journal_title:Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

    pub_type: 杂志文章,评审

    doi:10.1093/dote/dox161

    authors: Jansen SM,de Bruin DM,van Berge Henegouwen MI,Strackee SD,Veelo DP,van Leeuwen TG,Gisbertz SS

    更新日期:2018-06-01 00:00:00

  • Use of the Montreal global definition as an assessment of quality of life in reflux disease.

    abstract::According to the Montreal Consensus Group's classification, gastroesophageal reflux disease develops when the reflux of stomach contents causes troublesome symptoms and/or complications such as esophagitis. The characteristic gastroesophageal reflux disease symptoms included in this statement are retrosternal burning ...

    journal_title:Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

    pub_type: 杂志文章

    doi:10.1111/j.1442-2050.2011.01271.x

    authors: Sawaya RA,Macgill A,Parkman HP,Friedenberg FK

    更新日期:2012-08-01 00:00:00

  • Association of methylenetetrahydrofolate reductase and thymidylate synthase promoter polymorphisms with genetic susceptibility to esophageal and cardia cancer in a Chinese high-risk population.

    abstract:SUMMARY:Methylenetetrahydrofolate reductase (MTHFR) and thymidylate synthase (TS) are key enzymes in folate metabolism, which is essential for normal DNA methylation and synthesis. Common polymorphisms at the MTHFR nucleotides position 677 (C-T) and a 28-bp tandem repeat polymorphism (2R or 3R) in the TS promoter enhan...

    journal_title:Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

    pub_type: 杂志文章

    doi:10.1111/j.1442-2050.2005.00492.x

    authors: Wang LD,Guo RF,Fan ZM,He X,Gao SS,Guo HQ,Matsuo K,Yin LM,Li JL

    更新日期:2005-01-01 00:00:00

  • Adenocarcinoma of the rat esophagus in the presence of a proton pump inhibitor: a pilot study.

    abstract::This study examines the effects of a proton pump inhibitor on a rat model of duodenogastric reflux. Duodenoesophageal reflux was induced in 60 rats by performing a duodenesophagostomy. The study group received daily intraperitoneal injections of a proton pump inhibitor for 6 months and the control group received an eq...

    journal_title:Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

    pub_type: 杂志文章

    doi:10.1111/j.1442-2050.2001.00145.x

    authors: Moore KH,Barry P,Burn J,Falk G

    更新日期:2001-01-01 00:00:00

  • Comparison of the prognostic value of the 6th and 7th editions of the Union for International Cancer Control TNM staging system in patients with lower esophageal cancer undergoing neoadjuvant chemotherapy followed by surgery.

    abstract::Carcinoma of the esophagus is classified according to the Union for International Cancer Control (UICC) TNM staging system. The 7th edition of the UICC TNM staging system was published in 2009. This is the first study to compare the prognostic value of the TNM 6th and 7th editions in patients with esophageal carcinoma...

    journal_title:Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

    pub_type: 杂志文章

    doi:10.1111/j.1442-2050.2012.01350.x

    authors: Mehta SP,Jose P,Mirza A,Pritchard SA,Hayden JD,Grabsch HI

    更新日期:2013-02-01 00:00:00