Jackhammer esophagus: high-resolution manometry and therapeutic approach using peroral endoscopic myotomy (POEM).

abstract：:beta-Catenin, which is frequently overexpressed in a variety of human cancers including esophageal cancer, mediates cancer cell proliferation and tumor growth. In the present study, we used a human U6 promoter-driven DNA-template approach to induce short hairpin RNA (shRNA)-triggered RNA interference to silence beta-c...

journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

authors： Wang JS,Zheng CL,Wang YJ,Wen JF,Ren HZ,Liu Y,Jiang HY

更新日期：2009-01-01 00:00:00

abstract：:A 73-year-old man had a low anterior resection for a villous adenoma in the rectosigmoid. On the 4th day after surgery, he suddenly developed severe interscapular pain. Aortic dissection was ruled out, but endoscopy showed black mucosa of the entire esophagus. With conservative treatment, including proton pump inhibit...

journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

authors： Reichart M,Busch OR,Bruno MJ,Van Lanschot JJ

更新日期：2000-01-01 00:00:00

abstract：:Totally minimally invasive Ivor-Lewis esophagectomy (Ivor Lewis TMIE) is a technically challenging procedure and is associated with a learning curve. Refinement of surgical technique is an important part of this learning curve. However, detailed descriptions of these refinements according to the idea, development, exp...

journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

authors： Stenstra MHBC,van Workum F,van den Wildenberg FJH,Polat F,Rosman C

更新日期：2019-03-01 00:00:00

abstract：:Postoperative pulmonary complications (PPCs) after esophagectomy have been reported to occur in 15-30% of patients and are the most common causes of major morbidity and mortality. Risk factors for the development of PPCs include impairment in lung function, cardiac reserve, aerobic capacity, and body composition. Phys...

journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

authors： Feeney C,Reynolds JV,Hussey J

更新日期：2011-09-01 00:00:00

abstract：:Barrett's esophagus (BE), a premalignant condition for the development of esophageal adenocarcinoma (EAC), is a consequence of chronic gastroesophageal reflux disease (GERD). Although the incidence of EAC is increasing, a similar trend for BE is not clear. We aimed to evaluate the prevalence of newly diagnosed BE over...

journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

authors： Hamade N,Weng G,Desai M,Chandrasekar VT,Dasari C,Kennedy K,Sharma P

更新日期：2021-01-16 00:00:00

abstract：:Nowadays esophageal squamous cell carcinoma (ESCC) is primarily treated by a comprehensive approach combining surgical resection and neoadjuvant chemo- or radiotherapy. However, ESCC is resistant to radiation therapy, resulting in its invasion, infiltration, and metastasis. It usually has rapidly progressed and has a ...

journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

authors： Qian X,Tan C,Yang B,Wang F,Ge Y,Guan Z,Cai J

更新日期：2017-06-01 00:00:00

abstract：SUMMARY:Methylenetetrahydrofolate reductase (MTHFR) and thymidylate synthase (TS) are key enzymes in folate metabolism, which is essential for normal DNA methylation and synthesis. Common polymorphisms at the MTHFR nucleotides position 677 (C-T) and a 28-bp tandem repeat polymorphism (2R or 3R) in the TS promoter enhan...

journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

authors： Wang LD,Guo RF,Fan ZM,He X,Gao SS,Guo HQ,Matsuo K,Yin LM,Li JL

更新日期：2005-01-01 00:00:00

abstract：:In a prior study, baseline mutational load (ML) predicted progression to high-grade dysplasia (HGD) or esophageal adenocarcinoma (EAC) in Barrett's esophagus (BE) with an area under the curve (AUC) of 0.95. We aimed to validate the test characteristics of this predictive biomarker panel using crude DNA lysates in a la...

journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

authors： Eluri S,Klaver E,Duits LC,Jackson SA,Bergman JJ,Shaheen NJ

更新日期：2018-11-01 00:00:00

abstract：:This study assessed the clinical value of CYFRA 21-1 in comparison with squamous cell carcinoma antigen (SCC-Ag), carcinoembryonic antigen (CEA), and carbohydrate antigen 19-9 (CA19-9) in patients with esophageal squamous cell carcinoma. In 112 primary cancer patients, the diagnostic sensitivity of CYFRA 21-1 (33.9%) ...

journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

authors： Nakamura T,Ide H,Eguchi R,Hayashi K,Takasaki K,Watanabe S

更新日期：2017-11-01 00:00:00

abstract：:Neoadjuvant chemoradiotherapy (nCRT) followed by surgery is standard of care for locally advanced esophageal cancer in many countries. After nCRT up to one third of all patients have a pathologically complete response in the resection specimen, posing an ethical imperative to reconsider the necessity of standard surge...

journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

authors： Noordman BJ,Wijnhoven BPL,Lagarde SM,Biermann K,van der Gaast A,Spaander MCW,Valkema R,van Lanschot JJB

更新日期：2017-12-01 00:00:00

abstract：:Gastroesophageal reflux disease (GERD) is a common disorder of the upper gastrointestinal tract which is typically characterized by heartburn and acid regurgitation. These symptoms are widespread in the community and range from 2.5% to more than 25%. Economic analyses showed an increase in direct and indirect costs re...

journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

authors： Savarino E,de Bortoli N,De Cassan C,Della Coletta M,Bartolo O,Furnari M,Ottonello A,Marabotto E,Bodini G,Savarino V

更新日期：2017-02-01 00:00:00

abstract：:Esophagectomy is associated with substantial morbidity. Robotic surgery allows complex resections to be performed with potential benefits over conventional techniques. We applied this technology to transthoracic esophagectomy to assess safety, feasibility, and reliability of this technology. A retrospective cohort stu...

journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

authors： Meredith K,Huston J,Andacoglu O,Shridhar R

更新日期：2018-07-01 00:00:00

abstract：:Animal models of Barrett's metaplasia and esophageal adenocarcinoma are important to further characterize the disease and test potential therapies. This paper reviews the development of the surgical model of esophageal adenocarcinoma in the rat and considers whether this model provides a biologically accurate represen...

journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

authors： Hindmarsh A,Belshaw N,Mehta S,Johnson IT,Rhodes M

更新日期：2012-02-01 00:00:00

abstract：:Modern treatment of esophageal cancer is multimodal and highly dependent on a detailed diagnostic assessment of clinical stage, which includes nodal stage. Clinical appraisal of nodal stage is highly dependent on knowledge of normal radiological appearance, information of which is scarce. We aimed to describe lymph no...

journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

authors： Hansen T,Nilsson M,Lindholm D,Sundström J,Hedberg J

更新日期：2019-12-13 00:00:00

abstract：:Palliation of inoperable esophageal cancer with covered stents aims to relieve progressive dysphagia and improve health-related quality of life (HRQoL). Introducing a stent across the esophagogastric junction in lower third tumors may predispose to unchecked gastro-esophageal reflux (GER). Esophageal stents incorporat...

journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

authors： Power C,Byrne PJ,Lim K,Ravi N,Moore J,Fitzgerald T,Keeling PW,Reynolds JV

更新日期：2007-01-01 00:00:00

abstract：:Esophageal perforation is uncommon and traditionally has a high rate of morbidity and mortality. Our aim was to perform a 13-year retrospective review of the cases managed in our district general hospital. Thirty-four cases of esophageal perforation diagnosed between 1995 and 2008 were retrospectively analyzed. There ...

journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

authors： Griffiths EA,Yap N,Poulter J,Hendrickse MT,Khurshid M

更新日期：2009-01-01 00:00:00

abstract：:Biological plausibility and evidence from case series indicate that an increased body mass index could be a risk factor for Barrett's esophagus. The aim of this study was to assemble and appraise the available evidence on the association of body mass index and Barrett's esophagus in a narrative approach. A systematic ...

journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

authors： Seidel D,Muangpaisan W,Hiro H,Mathew A,Lyratzopoulos G

更新日期：2009-01-01 00:00:00

abstract：:High-resolution manometry identifies three subtypes of achalasia. However, type 3 differs from classic achalasia. Although opiates affect esophageal motility, opiate use and achalasia have not been studied. Patients with a new diagnosis of achalasia at Mayo Clinic Rochester between June 1, 2012 and January 3, 2014 wer...

journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

authors： Ravi K,Murray JA,Geno DM,Katzka DA

更新日期：2016-01-01 00:00:00

abstract：:Positive proximal resection margins are strongly associated with anastomotic recurrence in esophageal cancer. However, the prognostic significance of dysplastic proximal resection margins remains unclear. The aim of this study is to investigate whether the dysplastic proximal resection margin can predict anastomotic r...

journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

authors： Chen YH,Yeh CJ,Wen YW,Chuang WY,Chao YK

更新日期：2019-05-01 00:00:00

abstract：:Combined modality treatment for esophageal carcinoma seems to improve survival over surgery alone. Different combinations of cytotoxic drugs have been studied to improve antitumor efficacy and limit the toxicity of chemoradiotherapy (CRT) with inconsistent results. We present a prospective study of neoadjuvant CRT wit...

journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

authors： Zemanova M,Petruzelka L,Pazdro A,Kralova D,Smejkal M,Pazdrova G,Honova H

更新日期：2010-02-01 00:00:00

abstract：:Metastasis to the breast from extramammary malignancies is rare. This is the third case report of metastatic breast cancer from esophageal cancer. We report the clinical, radiographic, and pathologic findings of a 57-year-old woman who underwent esophagectomy for esophageal cancer and developed metastatic cancer 2 yea...

journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

authors： Shiraishi M,Itoh T,Furuyama K,Yamasaki S,Shimada Y,Hosotani R,Nakashima Y,Imamura M

更新日期：2001-01-01 00:00:00

abstract：:We performed a systematic review of epidemiological, diagnostic, and therapeutic outcomes of esophageal perforations. A systematic review was performed in PubMed database using the key-phrase 'esophageal perforation'. All studies regarding acute esophageal perforations were reviewed and parameters of epidemiology, dia...

journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

authors： Sdralis EIK,Petousis S,Rashid F,Lorenzi B,Charalabopoulos A

更新日期：2017-08-01 00:00:00

abstract：:Neoadjuvant chemotherapy may improve the outcome of esophageal cancer after esophagectomy, but is accompanied by considerable toxicity by collateral destruction of normal cells. Such side effects may be avoided by developing therapies that specifically target molecular characteristics of tumors. The aim of the present...

journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

authors： Boone J,van Hillegersberg R,Offerhaus GJ,van Diest PJ,Borel Rinkes IH,Ten Kate FJ

更新日期：2009-01-01 00:00:00

abstract：:Detailed data on patterns of esophageal bolus transport in patients with achalasia are still lacking. To study these we applied the novel technique of multichannel intraluminal impedance measurements. Ten patients with achalasia were studied using a 16 channel system. Liquid and semisolid boluses of 10 mL were applied...

journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

authors： Nguyen HN,Domingues GR,Winograd R,Lammert F,Silny J,Matern S

更新日期：2004-01-01 00:00:00

abstract：:Esophageal atresia (EA) occurs in one out of 2500 to 4500 live births. As the vast majority of infants are now surviving neonatal corrective surgery, the focus has shifted from mortality to morbidity associated with EA. However, little is known about its psychological morbidity. This paper synthesizes research and cli...

journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

authors： Caplan A

更新日期：2013-05-01 00:00:00

abstract：:Noncardiac chest pain (NCCP) is a common and challenging clinical problem. It is estimated that more than 70 million Americans (23% of the population) suffer from this condition yearly. Patients with NCCP represent a diagnostic dilemma. Their chest pain is often indistinguishable from cardiac pain leading to extensive...

journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

authors： Fass R,Achem SR

更新日期：2012-02-01 00:00:00

abstract：:Long-term survival after esophagectomy is improving, and hence, quality of life (QOL) of these patients has become a priority. There has been extensive debate regarding the optimal site of surgical anastomosis (cervical or intrathoracic). We aimed to evaluate the impact of anastomotic site on long-term QOL postesophag...

journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

authors： Wormald JC,Bennett J,van Leuven M,Lewis MP

更新日期：2016-01-01 00:00:00

abstract：:The objective of this article was to analyze 40 years of experience of colon interposition in the surgical treatment of caustic esophageal strictures from the standpoints of our long-term personal experience. Colon interposition has proved to be the most suitable type of reconstruction for esophageal corrosive strictu...

journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

authors： Knezević JD,Radovanović NS,Simić AP,Kotarac MM,Skrobić OM,Konstantinović VD,Pesko PM

更新日期：2007-01-01 00:00:00

abstract：:The placement of metal stents is often used as a palliative treatment for malignant esophageal stenosis. We designed a novel stent that has been used clinically since 2011, and we therefore performed a retrospective study to compare the therapeutic effects of this novel metal stent to a conventional partially covered ...

journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

authors： Chen H,Ni Z,Jing D,He L,Qiao L,Liu L,Wei X,Jiang M,Tang S,Xu H

更新日期：2017-02-01 00:00:00

abstract：:To ensure safe implementation of robot-assisted minimally invasive esophagectomy (RAMIE), the learning process should be optimized. This study aimed to report the results of a surgeon who implemented RAMIE in a German high-volume center by following a tailored and structured training pathway that involved proctoring. ...

journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

authors： Kingma BF,Hadzijusufovic E,Van der Sluis PC,Bano E,Lang H,Ruurda JP,Hillegersberg van R,Grimminger PP

更新日期：2020-11-26 00:00:00