Abstract：
:Detailed data on patterns of esophageal bolus transport in patients with achalasia are still lacking. To study these we applied the novel technique of multichannel intraluminal impedance measurements. Ten patients with achalasia were studied using a 16 channel system. Liquid and semisolid boluses of 10 mL were applied with the patients in a supine position. Patterns of bolus transport were determined and analyzed as compared to results obtained from 20 healthy subjects. The healthy subjects featured a unique typical primary peristalsis pattern independent of bolus viscosity. In contrast, achalasia patients demonstrated different impedance characteristics, including: (i) significantly lower baseline esophageal impedance during the resting state as compared with healthy volunteers (999 omega +/- 108 versus 2749 omega +/- 113); (ii) failed bolus transport through the esophagus in all cases; (iii) impedance evidence of luminal content regurgitation in 35% of the swallows (iv) impedance evidence of pathological air movement within the proximal esophagus during deglutition in 38% of the swallows, so called air trapping. Thus, impedance characteristics of achalasia have been defined and can be attributed to known symptoms of achalasia. They can be used as basic findings for further classification of pathological bolus transports in other esophageal motility disorders.
journal_name
Dis Esophagusjournal_title
Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagusauthors
Nguyen HN,Domingues GR,Winograd R,Lammert F,Silny J,Matern Sdoi
10.1111/j.1442-2050.2004.00372.xsubject
Has Abstractpub_date
2004-01-01 00:00:00pages
44-50issue
1eissn
1120-8694issn
1442-2050pii
DES372journal_volume
17pub_type
杂志文章abstract：:Thoracoscopic repair of esophageal atresia is gaining popularity worldwide attributable to availability and advances in minimally invasive instruments. In this report, we presented our experience with thoracoscopic esophageal atresia/tracheoesophageal fistula (EA/TEF) repair in our tertiary care institute. A prospecti...
journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus
pub_type： 杂志文章
doi：10.1093/dote/doaa001
更新日期：2020-02-12 00:00:00
abstract：:We studied the premalignant nature of achalasia using anti-Ki-67 and anti-p53 monoclonal antibodies immunohistochemically. In this study, four patients with esophageal carcinoma and achalasia were investigated. Three tumors were pT4 (UICC pTNM) and one tumor was pT1. The majority of non-malignant esophageal epithelium...
journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus
pub_type： 杂志文章
doi：10.1046/j.1442-2050.2000.00088.x
更新日期：2000-01-01 00:00:00
abstract：:Achalasia is a disorder of esophageal motility that has been well documented for over 300 years. Despite this, the initiating factor or factors and the underlying mechanisms leading to the characteristic features of achalasia, the absence of distal esophageal peristalsis and abnormal lower esophageal sphincter relaxat...
journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus
pub_type： 杂志文章,评审
doi：10.1111/j.1442-2050.2006.00569.x
更新日期：2006-01-01 00:00:00
abstract：:We examined the value of impedance monitoring in measuring bolus volume compared with videoesophagram. Eighty consecutive subjects were studied with simultaneous impedance-manometry-videoesophagram. A catheter with both an impedance electrode pair and a pressure transducer at four sites (5, 10, 15, 20 cm above lower e...
journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus
pub_type： 杂志文章
doi：10.1111/j.1442-2050.2011.01302.x
更新日期：2012-09-01 00:00:00
abstract：:Lugol chromoendoscopy (LCE) is a useful technique for visualizing superficial esophageal squamous cell carcinoma (SESCC), but the stimulating effect of the Lugol solution can sometimes cause clinical problems. Newly developed techniques such as narrow-band imaging (NBI) and autofluorescence imaging (AFI) enable SESCC ...
journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus
pub_type： 杂志文章
doi：10.1111/j.1442-2050.2008.00925.x
更新日期：2009-01-01 00:00:00
abstract：:Neoadjuvant chemoradiotherapy (nCRT) followed by surgery is standard of care for locally advanced esophageal cancer in many countries. After nCRT up to one third of all patients have a pathologically complete response in the resection specimen, posing an ethical imperative to reconsider the necessity of standard surge...
journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus
pub_type： 杂志文章,评审
doi：10.1093/dote/dox100
更新日期：2017-12-01 00:00:00
abstract：:Non-Hodgkin lymphoma involving the esophagus is very rare. Only a few cases have been reported in the English literature to date, and it accounts for less than 1% of all cases of gastrointestinal lymphoma. As this malignancy manifests as a submucosal tumor, pathological diagnosis by using a simple endoscopic biopsy al...
journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus
pub_type： 杂志文章,评审
doi：10.1111/dote.12309
更新日期：2016-10-01 00:00:00
abstract：:Postoperative pulmonary complications (PPCs) after esophagectomy have been reported to occur in 15-30% of patients and are the most common causes of major morbidity and mortality. Risk factors for the development of PPCs include impairment in lung function, cardiac reserve, aerobic capacity, and body composition. Phys...
journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus
pub_type： 杂志文章
doi：10.1111/j.1442-2050.2010.01171.x
更新日期：2011-09-01 00:00:00
abstract：:Placement of self-expanding metal stents (SEMS) for palliation of malignant stenoses at the gastroesophageal junction is often associated with stent migration and reflux symptoms. SEMS with an antireflux mechanism have been developed to overcome the latter problem. The aim of this study was to evaluate the safety and ...
journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus
pub_type： 临床试验,杂志文章
doi：10.1111/j.1442-2050.2007.00646.x
更新日期：2007-01-01 00:00:00
abstract：:Esophagectomy is associated with substantial morbidity. Robotic surgery allows complex resections to be performed with potential benefits over conventional techniques. We applied this technology to transthoracic esophagectomy to assess safety, feasibility, and reliability of this technology. A retrospective cohort stu...
journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus
pub_type： 杂志文章
doi：10.1093/dote/doy005
更新日期：2018-07-01 00:00:00
abstract：:Small-cell carcinoma of the esophagus is a rare and aggressive tumor with early widespread dissemination. In this retrospective study, we report clinical outcomes of limited-disease small-cell carcinoma of the esophagus from the analysis of nine patients. Between 2003 and 2006, nine consecutive patients with small-cel...
journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus
pub_type： 杂志文章
doi：10.1111/j.1442-2050.2008.00863.x
更新日期：2009-01-01 00:00:00
abstract：:The aim of this paper is to investigate the diagnostic value of histopathologic score and the dilated intercellular space (DIS) in patients with gastroesophageal reflux disease (GERD) and functional heartburn (FH). Participants with GERD symptoms including reflux esophagitis, non-erosive reflux disease (NERD), Barrett...
journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus
pub_type： 杂志文章
doi：10.1111/dote.12256
更新日期：2015-08-01 00:00:00
abstract：:The management of achalasia remains controversial, with little consensus on the optimal patient treatment pathway. In our own esophageal unit, we offer pneumatic dilatation as the initial therapy in most patients as first-line therapy. In this study, we aimed to examine the safety and efficacy of our own approach to t...
journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus
pub_type： 杂志文章
doi：10.1111/j.1442-2050.2010.01055.x
更新日期：2010-08-01 00:00:00
abstract：:Esophageal squamous cell carcinoma (ESCC) is one of the most frequently diagnosed cancers in China, but the etiology and mode of carcinogenesis of this disease remain poorly understood. Phosphatase and tensin homolog deleted on chromosome 10 (PTEN), as a negative regulator of Akt/mTOR pathway, frequently mutates or is...
journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus
pub_type： 杂志文章
doi：10.1111/dote.12448
更新日期：2017-02-01 00:00:00
abstract：:Gastric conduit used for reconstruction after esophagectomy for cancer has the potential to develop a metachronous neoplasm known as gastric tube cancer (GTC). The aim of this study was to review literature and evaluate outcomes and possible treatment strategies for GTC. A comprehensive systematic literature search wa...
journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus
pub_type： 杂志文章
doi：10.1093/dote/doz049
更新日期：2019-08-01 00:00:00
abstract：:Esophageal leiomyoma are usually intramural and the most common minimally invasive approach is thoracoscopic excision leaving the mucosa intact. We report the case of a 58-year-old woman who underwent laparoscopic excision of a pedunculated esophageal leiomyoma. ...
journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus
pub_type： 杂志文章
doi：10.1046/j.1442-2050.2001.00203.x
更新日期：2001-01-01 00:00:00
abstract：:One of the most common causes of a failed Nissen fundoplication is disruption of the crural repair. We investigated the thickness of the subdiaphragmatic fascia overlying the right and left limb of the right crus in cadavers to determine any difference. Sub-diaphragmatic fascia specimens were obtained from three sites...
journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus
pub_type： 杂志文章
doi：10.1111/j.1442-2050.2006.00554.x
更新日期：2006-01-01 00:00:00
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journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus
pub_type： 杂志文章
doi：10.1111/j.1442-2050.2005.00432.x
更新日期：2005-01-01 00:00:00
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journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus
pub_type： 杂志文章
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更新日期：1998-07-01 00:00:00
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journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus
pub_type： 杂志文章
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更新日期：2017-04-01 00:00:00
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journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus
pub_type： 杂志文章
doi：10.1111/j.1442-2050.2008.00913.x
更新日期：2009-01-01 00:00:00
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journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus
pub_type： 杂志文章
doi：10.1111/j.1442-2050.2007.00723.x
更新日期：2008-01-01 00:00:00
abstract：:Fifty-two patients presenting with upper or middle esophageal carcinoma after gastrectomy between 1980 and 2003 were analyzed retrospectively. Among them, there were five cases of total gastrectomy, six cases of proximal partial gastrectomy and 41 cases of distal subtotal gastrectomy. The interval between gastrectomy ...
journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus
pub_type： 杂志文章
doi：10.1111/j.1442-2050.2005.00500.x
更新日期：2005-01-01 00:00:00
abstract：:Multimodality treatment combining surgery and oncologic treatment has become widely applied in curative treatment of esophageal and gastroesophageal junction adenocarcinoma. There is a need for a standardized tumor regression grade scoring system for clinically relevant effects of neoadjuvant treatment effects. There ...
journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus
pub_type： 杂志文章
doi：10.1093/dote/doaa005
更新日期：2020-06-15 00:00:00
abstract：:The incidence of Candida infection has significantly increased over the recent years, becoming the fourth most common pathogens isolated in patients admitted to intensive care units (ICU). Mortality rates ranging between 6 and 38% have been reported to be associated with candidemia. Esophageal surgery may increase the...
journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus
pub_type： 杂志文章
doi：10.1046/j.1442-2050.2003.00297.x
更新日期：2003-01-01 00:00:00
abstract：:Transthoracic esophagectomy (TTE) is believed to have advantages for mediastinal lymphadenectomy in the treatment of resectable esophageal cancer despite its association with a greater incidence of pulmonary complications and postoperative mortality. Transhiatal esophagectomy is regarded as less invasive, though insuf...
journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus
pub_type： 杂志文章
doi：10.1111/dote.12345
更新日期：2016-07-01 00:00:00
abstract：:Patients with Barrett's esophagus are at risk for dysplasia and esophageal adenocarcinoma. Although surgery was the mainstay treatment for Barrett's dysplasia and cancer, patients with high-grade dysplasia and early cancers now have several nonsurgical treatment options. Most of the endoscopic therapies are relatively...
journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus
pub_type： 杂志文章
doi：10.1111/j.1442-2050.2012.01411.x
更新日期：2013-04-01 00:00:00
abstract：:Minimally invasive esophageal resection is a technically demanding procedure that may reduce patient morbidity and improve convalescence when compared with the open approach. Despite these proposed advantages, the minimally invasive approach has not been widely embraced and is routinely performed in only a few special...
journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus
pub_type： 杂志文章
doi：10.1111/j.1442-2050.2004.00383.x
更新日期：2004-01-01 00:00:00
abstract：:SUMMARY. We present a case of a 20-year-old, previously healthy, male student who presented with dysphagia secondary to mechanical esophageal obstruction that resolved spontaneously. Although our patient did not have 'classic' patient characteristics, we believe that the clinical evidence supports the conclusion that ...
journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus
pub_type： 杂志文章
doi：10.1111/j.1442-2050.2005.00462.x
更新日期：2005-01-01 00:00:00
abstract：:The aim of this study was to determine the influence of splenectomy on perioperative morbidity and mortality, as well as on the long-term survival after esophageal resection for carcinoma of the esophagus. From September 1985 to July 2003, 404 patients underwent surgery for esophageal carcinoma in our institution. Spl...
journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus
pub_type： 杂志文章
doi：10.1111/j.1442-2050.2005.00512.x
更新日期：2005-01-01 00:00:00
