Targets for molecular therapy in esophageal squamous cell carcinoma: an immunohistochemical analysis.

abstract：:Megaesophagus is the end-stage of achalasia cardiae. It is the result of peristaltic disorders and slow decompensation of the muscular layer of the esophagus. The aim of this article is to detail the diagnostic criteria and surgical management of megaesophagus. Criteria were acute bending of esophagus axis; lack of es...

journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

authors： Lewandowski A

更新日期：2009-01-01 00:00:00

abstract：:Small cell carcinoma arising in the esophagus is a relatively rare disease. In the more common small cell carcinoma of the lung, the diagnostic significance of several new markers has been recently reported. This study used immunohistochemical techniques in addition to clinicopathological analysis, in order to clarify...

journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

authors： Noguchi T,Takeno S,Kato T,Wada S,Noguchi T,Uchida Y,Kashima K,Yokoyama S

更新日期：2003-01-01 00:00:00

abstract：:Achalasia is a primary esophageal motility disorder. Unlike diffuse esophageal spasm, it has not previously been described in association with hereditary sensory and motor neuropathy (HSMN). An 18-year-old-male with HSMN with sensorineural deafness presented with a 2-day history of dysphagia to solids and liquids. Ach...

journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

authors： Asthana AK,Lubel JS,Kohn GP

更新日期：2016-08-01 00:00:00

abstract：:We report the case of a 63-year-old man who presented with weakness, fatigue, dehydration, confusion, abdominal pain, congestive heart failure and hypercalcemia. He expired and autopsy revealed an exulcerating carcinoma of the esophagus, invading the esophageal wall and metastasizing to the lungs, skin and lymph nodes...

journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

authors： Fereidooni F,Horvath E,Kovacs K

更新日期：2003-01-01 00:00:00

abstract：:The objective of this study is the feasibility of sequential endoscopic and endosonographic measurement of locoregional tumor load for the prediction of tumor recurrence in patients after neoadjuvant or definitive chemoradiotherapy, treated in curative intent for locally advanced esophageal carcinoma. In 67 patients w...

journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

authors： Bohle W,Kasper M,Zoller WG

更新日期：2017-10-01 00:00:00

abstract：:The sensitivity of cancers to radiotherapy or chemotherapy may be influenced by susceptibility to apoptosis. We evaluated whether expression of three proteins regulating apoptosis, p53, bcl-2, and bax, could predict the effect of radiotherapy in esophageal cancers. We used immunohistochemical staining for these protei...

journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

authors： Shimoji H,Miyazato H,Nakachi A,Kuniyoshi S,Isa T,Shiraishi M,Muto Y,Toda T

更新日期：2000-01-01 00:00:00

abstract：:An association between gastroesophageal reflux disease (GERD) and diabetes mellitus (DM) has been reported. Studies have not been population-based and have failed to include a representative sample of African American subjects. The aim of the study was to determine if DM is independently associated with GERD among urb...

journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

authors： Natalini J,Palit A,Sankineni A,Friedenberg FK

更新日期：2015-07-01 00:00:00

abstract：:Gastroesophageal reflux disease (GERD) is common in obese patients. The implications of obesity in the etiology, management and outcomes in treatment for GERD have become increasingly important due to an epidemic of obesity. The increasing prevalence of patients with both obesity and GERD merits evaluation of the appr...

journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

authors： Kendrick ML,Houghton SG

更新日期：2006-01-01 00:00:00

abstract：:The outcome of 211 patients undergoing laser therapy as palliation for inoperable carcinoma of the esophagus is presented. The median age was 73 (range 44-97). The histology was adenocarcinoma for 127 patients and squamous-cell carcinoma for 84 patients. For 133 patients, laser was the only therapy while 56 patients h...

journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

authors： Savage AP,Baigrie RJ,Cobb RA,Barr H,Kettlewell MG

更新日期：1997-10-01 00:00:00

abstract：:There has been increasing application of endoscopic ablation therapy for patients with high-grade dysplasia (HGD) and Barrett's esophagus (BE). Three cases are reported in which the patient developed adenocarcinoma of the gastric cardia after thermal ablation of HGD. A definition of BE including endoscopic abnormality...

journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

authors： Sampliner RE,Camargo E,Prasad AR

更新日期：2006-01-01 00:00:00

abstract：:Perforations of the esophagus are uncommon complications of flexible gastrointestinal endoscopy. Perforations after endoscopy are likely to occur in the cervical esophagus, where fiber insertion is difficult anatomically. The diagnosis should be made as soon as possible, because mediastinitis and sepsis frequently dev...

journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

authors： Sato S,Kajiyama Y,Kuniyasu T,Machida M,Ouchi K,Sakai N,Sakamoto S,Iwanuma Y,Kamano T,Okamura S,Nagahama A,Tsurumaru M

更新日期：2002-01-01 00:00:00

abstract：:Esophageal adenocarcinoma (EAC) has had the fastest increasing incidence of any solid tumor in the United States in the last 30 years. Long standing gastroesophageal reflux disease is a well-established risk factor with strong associations with obesity, alcohol and tobacco. However, there are likely additional contrib...

journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

authors： Chang C,Worrell SG

更新日期：2020-12-07 00:00:00

abstract：:Esophagectomy is an extensive procedure with severe postoperative effects. It can be assumed that the greater the trauma, the longer the nutritional recovery. This retrospective observational single-center cohort study compared weight development after esophagectomy with open and minimally invasive techniques. Three g...

journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

authors： Ericson J,Lundell L,Klevebro F,Kamiya S,Nilsson M,Rouvelas I

更新日期：2019-04-01 00:00:00

abstract：:Endoscopic therapy (ablation +/- endoscopic resection) for high-grade dysplasia and/or intramucosal carcinoma (IMC) of the esophagus has demonstrated promising results. However, there is a concern that a curable, local disease may progress to systemic disease with repeated endotherapy. We performed a retrospective rev...

journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

authors： Hunt BM,Louie BE,Dunst CM,Lipham JC,Farivar AS,Sharata A,Aye RW

更新日期：2014-05-01 00:00:00

abstract：:The effect of endoscopic submucosal dissection (ESD) on esophageal motility remains unknown. Therefore, the aim of this study is to elucidate changes in esophageal motility after ESD along with the cause of dysphagia using high-resolution manometry (HRM). This is a before-and-after trial of the effect of ESD on the es...

journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

authors： Takahashi K,Sato Y,Takeuchi M,Sato H,Nakajima N,Ikarashi S,Hayashi K,Mizuno KI,Honda Y,Hashimoto S,Yokoyama J,Terai S

更新日期：2017-11-01 00:00:00

abstract：:The objective of this article was to analyze 40 years of experience of colon interposition in the surgical treatment of caustic esophageal strictures from the standpoints of our long-term personal experience. Colon interposition has proved to be the most suitable type of reconstruction for esophageal corrosive strictu...

journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

authors： Knezević JD,Radovanović NS,Simić AP,Kotarac MM,Skrobić OM,Konstantinović VD,Pesko PM

更新日期：2007-01-01 00:00:00

abstract：:Combined modality treatment for esophageal carcinoma seems to improve survival over surgery alone. Different combinations of cytotoxic drugs have been studied to improve antitumor efficacy and limit the toxicity of chemoradiotherapy (CRT) with inconsistent results. We present a prospective study of neoadjuvant CRT wit...

journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

authors： Zemanova M,Petruzelka L,Pazdro A,Kralova D,Smejkal M,Pazdrova G,Honova H

更新日期：2010-02-01 00:00:00

abstract：:Although treatment for esophageal motility disorder improves dysphagia and increases body weight, the effect of the treatment on body composition is unclear. This study aimed to assess the change in body composition between before and after treatment, the preoperative predictors of muscle increase, and the association...

journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

authors： Abe H,Tanaka S,Kawara F,Toyonaga T,Ariyoshi R,Nakano Y,Sakaguchi H,Morita Y,Umegaki E,Kodama Y

更新日期：2019-08-01 00:00:00

abstract：:In summary, the role of long esophagomyotomy for patients with DES and related motor disorders remains controversial. The results are poorer than those following esophagomyotomy for achalasia, and long-term postoperative follow-up of these patients is essential because early good results may be misleading. Two methods...

journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

authors： Ellis FH Jr

更新日期：1998-10-01 00:00:00

abstract：:Barrett's esophagus (BE) is the strongest risk factor for the development of esophageal adenocarcinoma. However, the risk of cancer progression is difficult to ascertain in individuals, as a significant number of patients with BE do not necessarily progress to esophageal adenocarcinoma. There are several issues with t...

journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

authors： Timmer MR,Sun G,Gorospe EC,Leggett CL,Lutzke L,Krishnadath KK,Wang KK

更新日期：2013-08-01 00:00:00

abstract：:Multimodality treatment combining surgery and oncologic treatment has become widely applied in curative treatment of esophageal and gastroesophageal junction adenocarcinoma. There is a need for a standardized tumor regression grade scoring system for clinically relevant effects of neoadjuvant treatment effects. There ...

journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

authors： Klevebro F,Tsekrekos A,Low D,Lundell L,Vieth M,Detlefsen S

更新日期：2020-06-15 00:00:00

abstract：:Small-cell carcinoma of the esophagus is a rare and aggressive tumor with early widespread dissemination. In this retrospective study, we report clinical outcomes of limited-disease small-cell carcinoma of the esophagus from the analysis of nine patients. Between 2003 and 2006, nine consecutive patients with small-cel...

journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

authors： Yamashita H,Nakagawa K,Asari T,Murakami N,Igaki H,Okuma K,Ohtomo K

更新日期：2009-01-01 00:00:00

abstract：:Chemoradiotherapy is a standard treatment for esophageal carcinoma. This study evaluated the docetaxel-based definitive concomitant chemoradiotherapy in patients with esophageal squamous cell carcinoma to determine its clinical response and overall survival. In this unicenter trail, we enrolled 59 patients with histol...

journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

authors： Li QQ,Liu MZ,Hu YH,Liu H,He ZY,Lin HX

更新日期：2010-04-01 00:00:00

abstract：BACKGROUND AND AIMS:There has been a recent increase in the incidence of oropharyngeal cancer (OPC) associated with high-risk human papilloma virus (HPV) infection. We investigated the incidence of esophageal papilloma and the presence of high-risk HPV infection. METHODS:This is a cross-sectional study conducted at a ...

journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

authors： Pantham G,Ganesan S,Einstadter D,Jin G,Weinberg A,Fass R

更新日期：2017-01-01 00:00:00

abstract：:Surgically induced duodenal reflux results in cancer development in the rat esophagus. One proposed mechanism of carcinogenesis relies on the production of carcinogens in the presence of bacterial overgrowth. Against this background, intestinal microflora in the rat jejunum was analyzed before and after reflux-inducin...

journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

authors： Fein M,Fuchs KH,DeMeester TR,Peters JH,Wittmann D,Weig M

更新日期：2000-01-01 00:00:00

abstract：:One-lung ventilation (OLV) is applied during esophagectomy to improve exposure during the thoracic part of the operation. Collapse of lung tissue, shunting of pulmonary blood flow, and changes in alveolar oxygenation during and after OLV may possibly induce an ischemia-reperfusion response in the lung, which may affec...

journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

authors： Lund M,Ny L,Malmström RE,Lundberg JO,Öst Å,Björnstedt M,Lundell L,Tsai JA

更新日期：2013-11-01 00:00:00

abstract：:Human epidermal growth factor receptor 2 (HER2) is involved in the malignant progression of several human cancers, including esophageal adenocarcinoma (EAC). The purpose of this study was to evaluate HER2 overexpression and to explore the feasibility of confocal laser endomicroscopy for in vivo molecular imaging of HE...

journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

authors： Realdon S,Dassie E,Fassan M,Dall'Olmo L,Hatem G,Buda A,Arcidiacono D,Diamantis G,Zhang H,Greene MI,Sturniolo GC,Rugge M,Alberti A,Battaglia G

更新日期：2015-05-01 00:00:00

abstract：:The aim of the present study was to evaluate the long-term outcomes of laparoscopic Heller myotomy with Dor fundoplication (LHD) and its effect on chest pain. Between June 1995 and August 2009, a total of 35 patients with achalasia underwent an LHD. The symptom scores were calculated by combining the frequency and the...

journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

authors： Sasaki A,Obuchi T,Nakajima J,Kimura Y,Koeda K,Wakabayashi G

更新日期：2010-05-01 00:00:00

abstract：:The incidence of Candida infection has significantly increased over the recent years, becoming the fourth most common pathogens isolated in patients admitted to intensive care units (ICU). Mortality rates ranging between 6 and 38% have been reported to be associated with candidemia. Esophageal surgery may increase the...

journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

authors： Bonavina L,Incarbone R,Reitano M,Tortorano A,Viviani M,Peracchia A

更新日期：2003-01-01 00:00:00

abstract：:There are limited data concerning the effects of 5-HT(1A) receptor activation on esophageal motility. Sumatriptan, a 5-HT(1A) receptor agonist, was recently reported to enhance esophageal peristalsis after intravenous administration. Buspirone, an orally available 5-HT(1A) receptor agonist, was shown to modulate gastr...

journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

authors： Di Stefano M,Papathanasopoulos A,Blondeau K,Vos R,Boecxstaens V,Farré R,Rommel N,Tack J

更新日期：2012-07-01 00:00:00