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Viruses and esophageal cancer.

Abstract：

:Esophageal adenocarcinoma (EAC) has had the fastest increasing incidence of any solid tumor in the United States in the last 30 years. Long standing gastroesophageal reflux disease is a well-established risk factor with strong associations with obesity, alcohol and tobacco. However, there are likely additional contributing factors. Viruses such as human papillomavirus, ebstein-barr virus and herpes simplex virus have been implicated in the pathogenesis of esophageal cancer. This review will discuss the known literature linking viruses to esophageal adenocarcinoma and consider future relationships such as identifying prognostic and predictive molecular biomarkers to guide therapies.

journal_name

Dis Esophagus

journal_title

Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

authors

Chang C,Worrell SG

doi

10.1093/dote/doaa036

subject

Has Abstract

pub_date

2020-12-07 00:00:00

issue

12

eissn

1120-8694

issn

1442-2050

pii

5847897

journal_volume

33

pub_type

杂志文章

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