Abstract：
:Several endoluminal methods of treating gastroesophageal reflux disease (GERD) have either been approved, or are under investigation and development. This review outlines the two approved methods (Bard's endoluminal sewing machine and Curon's Stretta radiofrequency treatment), and describes the available data on new methods under investigation. The various methods can be divided into three broad categories: methods that create a controlled stricture, methods that bulk the gastroesophageal junction, and methods that attempt to create a fundoplication. The pros and cons of each method are discussed. Unlike medical treatment, these methods attack the reflux itself, not just the symptoms. This is a promising approach. However, the controlled stricture and bulking methods do not approach the success rate of a standard fundoplication.
journal_name
Dis Esophagusjournal_title
Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagusauthors
Roy-Shapira A,Stein HJ,Scwartz D,Fich A,Sonnenschein Edoi
10.1046/j.1442-2050.2002.00242.xsubject
Has Abstractpub_date
2002-01-01 00:00:00pages
132-6issue
2eissn
1120-8694issn
1442-2050pii
242journal_volume
15pub_type
杂志文章,评审abstract：:Surgically induced duodenal reflux results in cancer development in the rat esophagus. One proposed mechanism of carcinogenesis relies on the production of carcinogens in the presence of bacterial overgrowth. Against this background, intestinal microflora in the rat jejunum was analyzed before and after reflux-inducin...
journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus
pub_type： 杂志文章
doi：10.1046/j.1442-2050.2000.00023.x
更新日期：2000-01-01 00:00:00
abstract：:Paraesophageal herniation can cause massive bleeding, strangulation or perforation. This study reviews the experience with 24 patients (74.6 years, range 63-89 years, 20 males, 4 females) with a total or near-total intrathoracic stomach, managed at the Royal Lancaster Infirmary. All patients were symptomatic with 3/24...
journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus
pub_type： 杂志文章
doi：10.1093/dote/11.3.177
更新日期：1998-07-01 00:00:00
abstract：:Curative treatment of esophageal cancer with definitive or preoperative high-dose chemoradiotherapy inflicts a major strain on the patients with potentially severe physical, emotional, and social consequences. The aim of this study was to assess various aspects of quality of life and fatigue in long-term survivors fol...
journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus
pub_type： 杂志文章
doi：10.1111/j.1442-2050.2010.01104.x
更新日期：2011-01-01 00:00:00
abstract：:The cancer stem cell theory states that cancers contain tumor-forming cells that have the ability to self-renew as well as give rise to cells that differentiate. Cancer stem cells have been identified in several solid tumors, but stem cells in normal human esophagus or in Barrett's esophagus or adenocarcinoma have not...
journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus
pub_type： 杂志文章
doi：10.1111/j.1442-2050.2010.01061.x
更新日期：2010-09-01 00:00:00
abstract：:The progression of certain primary esophageal motor disorders to achalasia has been documented; however, the true incidence of this decay is still elusive. This study aims to evaluate: (i) the incidence of the progression of diffuse esophageal spasm to achalasia, and (ii) predictive factors to this progression. Thirty...
journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus
pub_type： 杂志文章
doi：10.1111/j.1442-2050.2012.01377.x
更新日期：2013-07-01 00:00:00
abstract：:Detailed data on patterns of esophageal bolus transport in patients with achalasia are still lacking. To study these we applied the novel technique of multichannel intraluminal impedance measurements. Ten patients with achalasia were studied using a 16 channel system. Liquid and semisolid boluses of 10 mL were applied...
journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus
pub_type： 杂志文章
doi：10.1111/j.1442-2050.2004.00372.x
更新日期：2004-01-01 00:00:00
abstract：:Para-aortic lymph node (PALN) recurrence is often seen in patients with lower thoracic esophageal cancer treated by esophagectomy with extended lymph node dissection. However, the clinicopathological characteristics of patients with PALN metastasis and the significance of PALN dissection are unknown. A total of 283 pa...
journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus
pub_type： 杂志文章
doi：10.1111/j.1442-2050.2011.01222.x
更新日期：2012-02-01 00:00:00
abstract：:Although malignant diseases are known to be associated with immune suppression, detailed mechanisms of this phenomenon are still unknown. NKG2D is an activating cell surface receptor expressed by natural killer (NK) cells and CD8+ T cells, and it has been reported that NKG2D engagement is extremely important for T cel...
journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus
pub_type： 杂志文章
doi：10.1111/j.1442-2050.2008.00855.x
更新日期：2009-01-01 00:00:00
abstract：:Esophagectomy is an extensive procedure with severe postoperative effects. It can be assumed that the greater the trauma, the longer the nutritional recovery. This retrospective observational single-center cohort study compared weight development after esophagectomy with open and minimally invasive techniques. Three g...
journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus
pub_type： 杂志文章
doi：10.1093/dote/doy075
更新日期：2019-04-01 00:00:00
abstract：:Esophageal squamous cell carcinoma (ESCC) is one of the most frequently diagnosed cancers in China, but the etiology and mode of carcinogenesis of this disease remain poorly understood. Phosphatase and tensin homolog deleted on chromosome 10 (PTEN), as a negative regulator of Akt/mTOR pathway, frequently mutates or is...
journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus
pub_type： 杂志文章
doi：10.1111/dote.12448
更新日期：2017-02-01 00:00:00
abstract：:Lugol chromoendoscopy (LCE) is a useful technique for visualizing superficial esophageal squamous cell carcinoma (SESCC), but the stimulating effect of the Lugol solution can sometimes cause clinical problems. Newly developed techniques such as narrow-band imaging (NBI) and autofluorescence imaging (AFI) enable SESCC ...
journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus
pub_type： 杂志文章
doi：10.1111/j.1442-2050.2008.00925.x
更新日期：2009-01-01 00:00:00
abstract：:The sensitivity of cancers to radiotherapy or chemotherapy may be influenced by susceptibility to apoptosis. We evaluated whether expression of three proteins regulating apoptosis, p53, bcl-2, and bax, could predict the effect of radiotherapy in esophageal cancers. We used immunohistochemical staining for these protei...
journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus
pub_type： 杂志文章
doi：10.1046/j.1442-2050.2000.00097.x
更新日期：2000-01-01 00:00:00
abstract：:Minimally invasive esophageal resection is a technically demanding procedure that may reduce patient morbidity and improve convalescence when compared with the open approach. Despite these proposed advantages, the minimally invasive approach has not been widely embraced and is routinely performed in only a few special...
journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus
pub_type： 杂志文章
doi：10.1111/j.1442-2050.2004.00383.x
更新日期：2004-01-01 00:00:00
abstract：OBJECTIVE:To determine the contribution of mechanical factors to the function of different types of fundoplication. DESIGN AND SETTING:An experimental bench-top study using abattoir-sourced pig esophagus and stomach placed on a tray. Preliminary esophageal myotomy ensured free reflux of 'intragastric fluid'. INTERVEN...
journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus
pub_type： 杂志文章
doi：10.1093/dote/10.2.110
更新日期：1997-04-01 00:00:00
abstract：:Squamous cell carcinoma of the esophagus is a cancer with a high incidence in South Africa. We have investigated the prognostic value of telomerase activity in tumors as well as nearby normal tissue. Biopsies from 98 patients (71 men and 27 women) were analyzed using an adaptation of the TRAP assay. We found all tumor...
journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus
pub_type： 杂志文章
doi：10.1111/j.1442-2050.2004.00417.x
更新日期：2004-01-01 00:00:00
abstract：:Long-term survival after esophagectomy is improving, and hence, quality of life (QOL) of these patients has become a priority. There has been extensive debate regarding the optimal site of surgical anastomosis (cervical or intrathoracic). We aimed to evaluate the impact of anastomotic site on long-term QOL postesophag...
journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus
pub_type： 杂志文章
doi：10.1111/dote.12301
更新日期：2016-01-01 00:00:00
abstract：:Progressive dysphagia of unknown etiology may still provide a diagnostic challenge despite an increase in the number and quality of investigations available. We describe a 64-year-old man who presented with progressive dysphagia and weight loss. Following a number of investigations, a diagnosis of diffuse esophageal l...
journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus
pub_type： 杂志文章
doi：10.1111/j.1442-2050.2010.01114.x
更新日期：2011-04-01 00:00:00
abstract：:The development of an adenocarcinoma in a reconstructed tube after subtotal esophagectomy for esophagus squamous cell carcinoma (ESCC) is uncommon and has been reported in articles from the Japanese medical community. We report three cases of patients who had this clinical presentation. We suggest an approach to posto...
journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus
pub_type： 杂志文章
doi：10.1046/j.1442-2050.2003.00317.x
更新日期：2003-01-01 00:00:00
abstract：:Despite symptom improvement offered to achalasia patients by either pneumatic dilation or surgical myotomy, 10% to 15% of those so treated will present progressive deterioration of their esophageal function and up to 5% may eventually require an esophagectomy. The natural evolution of achalasia to its end stage as wel...
journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus
pub_type： 杂志文章,评审
doi：10.1111/j.1442-2050.2010.01157.x
更新日期：2012-05-01 00:00:00
abstract：:Dr. Herman Boerhaave (1668-1738) first described esophageal rupture and the subsequent mediastinal sepsis based upon his careful clinical and autopsy findings and hundreds of references have since been written about Boerhaave's syndrome. Several fine historical accounts of this brilliant scientist have been published ...
journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus
pub_type： 传,历史文章,杂志文章
doi：10.1111/j.1442-2050.2006.00556.x
更新日期：2006-01-01 00:00:00
abstract：:Biological plausibility and evidence from case series indicate that an increased body mass index could be a risk factor for Barrett's esophagus. The aim of this study was to assemble and appraise the available evidence on the association of body mass index and Barrett's esophagus in a narrative approach. A systematic ...
journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus
pub_type： 杂志文章,评审
doi：10.1111/j.1442-2050.2009.00967.x
更新日期：2009-01-01 00:00:00
abstract：:It is essential to dissect an adequate number of lymph nodes (LNs) to ensure staging accuracy during esophagectomy with or without neoadjuvant therapy. We developed a statistical model to quantify the probability of precise nodal staging based on previous studies. Esophageal cancer patients who underwent esophagectomy...
journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus
pub_type： 杂志文章
doi：10.1093/dote/doz009
更新日期：2020-01-16 00:00:00
abstract：:Chagas' disease and idiopathic achalasia have similar esophageal manifestations such as absent or incomplete lower esophageal sphincter relaxation and aperistalsis in the esophageal body (alterations seen mainly in the distal esophageal body). Our aim in this paper was to study the response of the proximal esophageal ...
journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus
pub_type： 杂志文章
doi：10.1111/j.1442-2050.2006.00601.x
更新日期：2006-01-01 00:00:00
abstract：:Modern treatment of esophageal cancer is multimodal and highly dependent on a detailed diagnostic assessment of clinical stage, which includes nodal stage. Clinical appraisal of nodal stage is highly dependent on knowledge of normal radiological appearance, information of which is scarce. We aimed to describe lymph no...
journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus
pub_type： 杂志文章
doi：10.1093/dote/doy120
更新日期：2019-12-13 00:00:00
abstract：:The outcome of 211 patients undergoing laser therapy as palliation for inoperable carcinoma of the esophagus is presented. The median age was 73 (range 44-97). The histology was adenocarcinoma for 127 patients and squamous-cell carcinoma for 84 patients. For 133 patients, laser was the only therapy while 56 patients h...
journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus
pub_type： 杂志文章
doi：10.1093/dote/10.4.243
更新日期：1997-10-01 00:00:00
abstract：:Megaesophagus is the end-stage of achalasia cardiae. It is the result of peristaltic disorders and slow decompensation of the muscular layer of the esophagus. The aim of this article is to detail the diagnostic criteria and surgical management of megaesophagus. Criteria were acute bending of esophagus axis; lack of es...
journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus
pub_type： 杂志文章
doi：10.1111/j.1442-2050.2008.00897.x
更新日期：2009-01-01 00:00:00
abstract：:Animal models of Barrett's metaplasia and esophageal adenocarcinoma are important to further characterize the disease and test potential therapies. This paper reviews the development of the surgical model of esophageal adenocarcinoma in the rat and considers whether this model provides a biologically accurate represen...
journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus
pub_type： 杂志文章
doi：10.1111/j.1442-2050.2011.01228.x
更新日期：2012-02-01 00:00:00
abstract：:Barrett's esophagus with high-grade dysplasia (BEHGD) and intramucosal esophageal adenocarcinoma (IMC) can be treated by radiofrequency ablation (RFA) and endoscopic mucosal resection (EMR). Efficacy of RFA and EMR in academic medical centers has been demonstrated in previous studies. However, the clinical effectivene...
journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus
pub_type： 杂志文章
doi：10.1093/dote/dox126
更新日期：2018-01-01 00:00:00
abstract：:To ensure safe implementation of robot-assisted minimally invasive esophagectomy (RAMIE), the learning process should be optimized. This study aimed to report the results of a surgeon who implemented RAMIE in a German high-volume center by following a tailored and structured training pathway that involved proctoring. ...
journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus
pub_type： 杂志文章
doi：10.1093/dote/doaa047
更新日期：2020-11-26 00:00:00
abstract：:Fifty-two patients presenting with upper or middle esophageal carcinoma after gastrectomy between 1980 and 2003 were analyzed retrospectively. Among them, there were five cases of total gastrectomy, six cases of proximal partial gastrectomy and 41 cases of distal subtotal gastrectomy. The interval between gastrectomy ...
journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus
pub_type： 杂志文章
doi：10.1111/j.1442-2050.2005.00500.x
更新日期：2005-01-01 00:00:00
