Impact of air pollution on renal outcomes: a systematic review and meta-analysis protocol.

abstract：OBJECTIVE:Lung cancer is increasingly recognised as a heterogeneous disease. Recent advances with targeted therapies for lung cancer with oncogenic mutations have greatly improved the prognosis for this subset of patients, yet little is known about their experiences. This study aimed to identify the needs and explore t...

journal_title：BMJ open

authors： Al Achkar M,Marchand L,Thompson M,Chow LQM,Revere D,Baldwin LM

更新日期：2020-03-23 00:00:00

abstract：OBJECTIVES:To establish the rates of publication and reporting of results for interventional clinical trials across Polish academic medical centres (AMCs) completed between 2009 and 2013. We aim also to compare the publication and reporting success between adult and paediatric trials. DESIGN:Cross-sectional study. SE...

journal_title：BMJ open

authors： Strzebonska K,Wasylewski MT,Zaborowska L,Riedel N,Wieschowski S,Strech D,Waligora M

更新日期：2020-01-22 00:00:00

abstract：OBJECTIVES:To investigate if centre-specific levels of perinatal interventional activity were associated with neonatal and neurodevelopmental outcome at 2 years of age in two separately analysed cohorts of infants: cohort A born at 22-25 and cohort B born at 26-27 gestational weeks, respectively. DESIGN:Geographically...

journal_title：BMJ open

authors： Adams M,Berger TM,Borradori-Tolsa C,Bickle-Graz M,Grunt S,Gerull R,Bassler D,Natalucci G,Swiss Neonatal Network & Follow-Up Group.

更新日期：2019-03-15 00:00:00

abstract：OBJECTIVE:Foot problems (FP) may be considered to be a prevalent conditions in people but there is limited evidence of their effect on the quality of life (QoL) related to foot health in men and women. The aim of this study was to assess the impact of FPs on both overall foot health and QoL, stratified by gender. DESI...

journal_title：BMJ open

authors： López-López D,Becerro-de-Bengoa-Vallejo R,Losa-Iglesias ME,Palomo-López P,Rodríguez-Sanz D,Brandariz-Pereira JM,Calvo-Lobo C

更新日期：2018-10-18 00:00:00

abstract：BACKGROUND:X linked intellectual disability (XLID) syndromes account for a substantial number of males with ID. Much progress has been made in identifying the genetic cause in many of the syndromes described 20-40 years ago. Next generation sequencing (NGS) has contributed to the rapid discovery of XLID genes and ident...

journal_title：BMJ open

authors： Friez MJ,Brooks SS,Stevenson RE,Field M,Basehore MJ,Adès LC,Sebold C,McGee S,Saxon S,Skinner C,Craig ME,Murray L,Simensen RJ,Yap YY,Shaw MA,Gardner A,Corbett M,Kumar R,Bosshard M,van Loon B,Tarpey PS,Abidi F,G

更新日期：2016-04-29 00:00:00

abstract：INTRODUCTION:Daily radiotherapy delivered with radiosensitisation offers patients with muscle invasive bladder cancer (MIBC) comparable outcomes to cystectomy with functional organ preservation. Most recurrences following radiotherapy occur within the bladder. Increasing the delivered radiotherapy dose to the tumour ma...

journal_title：BMJ open

authors： Hafeez S,Webster A,Hansen VN,McNair HA,Warren-Oseni K,Patel E,Choudhury A,Creswell J,Foroudi F,Henry A,Kron T,McLaren DB,Mitra AV,Mostafid H,Saunders D,Miles E,Griffin C,Lewis R,Hall E,Huddart R

更新日期：2020-12-31 00:00:00

abstract：OBJECTIVE:How researchers' contributions relate to author order on the byline remains unclear. We sought to identify researchers' contributions associated with author order, and to explore the existence of author profiles. DESIGN:Observational study. SETTING:Published record. PARTICIPANTS:1139 authors of 119 researc...

journal_title：BMJ open

authors： Perneger TV,Poncet A,Carpentier M,Agoritsas T,Combescure C,Gayet-Ageron A

更新日期：2017-06-24 00:00:00

abstract：INTRODUCTION:In developed countries, substituting physicians with nurse practitioners, physician assistants and nurses (physician substitution) occurs in nursing homes as an answer to the challenges related to the ageing population and the shortage of staff, as well as to guarantee the quality of nursing home care. How...

journal_title：BMJ open

authors： Lovink MH,Persoon A,van Vught AJAH,Schoonhoven L,Koopmans RTCM,Laurant MGH

更新日期：2017-06-08 00:00:00

abstract：OBJECTIVES:There is a wide variation between European countries in antibiotic prescribing for patients in primary care with lower respiratory tract infection (LRTI) that is not explained by case mix and clinical factors alone. Variation in antibiotic prescribing that is not warranted by differences in illness and clini...

journal_title：BMJ open

authors： Brookes-Howell L,Hood K,Cooper L,Little P,Verheij T,Coenen S,Godycki-Cwirko M,Melbye H,Borras-Santos A,Worby P,Jakobsen K,Goossens H,Butler CC

更新日期：2012-08-22 00:00:00

abstract：OBJECTIVES:The use of psychoactive prescription medication is increasing in the general population. This is a cause for concern, particularly among the elderly, where physiological changes related to senescence increase the risk for adverse effects. While previous studies regarding psychoactive substance use have gener...

journal_title：BMJ open

authors： Gamboa D,Jørgenrud B,Bryun EA,Vindenes V,Koshkina EA,Nadezhdin AV,Kabashi S,Tetenova EJ,Berg T,Nyman AAT,Kolgashkin AJ,Petukhov AE,Perekhodov SN,Davydova EN,Lerdal A,Nordby G,Bogstrand ST

更新日期：2020-09-17 00:00:00

abstract：OBJECTIVES:The objective of this study was to investigate the role stressors, sociodemographic characteristics and job tasks of health surveillance assistants (HSAs) and to explore major predictors of role stressors and job satisfaction of HSAs in Malawi. SETTING:Data were collected from health centres and hospitals o...

journal_title：BMJ open

authors： Ntopi S,Chirwa E,Maluwa A

更新日期：2020-11-14 00:00:00

abstract：OBJECTIVES:The objective of this study was to explore whether reducing the material supplied to external experts during peer review and decreasing the burden of response would maintain review quality into prioritising research questions for a major research funder. METHODS AND ANALYSIS:Clinical experts who agreed to r...

journal_title：BMJ open

authors： Cook A,Streit E,Davage G

更新日期：2017-08-21 00:00:00

abstract：BACKGROUND:Mild traumatic brain injury (mTBI) is a common injury among military personnel serving in Iraq or Afghanistan. The impact of repeated episodes of combat mTBI is unknown. OBJECTIVE:To evaluate relationships among mTBI, post-traumatic stress disorder (PTSD) and neurological deficits (NDs) in US veterans who s...

journal_title：BMJ open

authors： Ruff RL,Riechers RG 2nd,Wang XF,Piero T,Ruff SS

更新日期：2012-03-18 00:00:00

abstract：INTRODUCTION:Circulating prostaglandin E2 levels are elevated in acutely decompensated cirrhosis and have been shown to contribute to immune suppression. Albumin binds to and inactivates this immune-suppressive lipid mediator. Human albumin solution (HAS) could thus be repurposed as an immune-restorative drug in these ...

journal_title：BMJ open

authors： China L,Skene SS,Bennett K,Shabir Z,Hamilton R,Bevan S,Chandler T,Maini AA,Becares N,Gilroy D,Forrest EH,O'Brien A

更新日期：2018-10-21 00:00:00

abstract：INTRODUCTION:There is a growing number of randomised controlled trials (RCTs) that focus on functional changes in the brain detected by functional MRI (fMRI) and gut microbiota composition changes after using probiotics.However, the effect of probiotics on functional changes in the brain through gut microbiota remains ...

journal_title：BMJ open

authors： Liu L,Ni X,Tian T,Li X,Li F,Sun M,Chen J,Zhou S,Zhao L

更新日期：2020-08-11 00:00:00

abstract：OBJECTIVE:Previous systematic reviews were not restricted to either primary or secondary prevention trials, this study aimed to investigate the effects of reduced and/or modified fat diets and dietary fatty acids on all-cause mortality, cardiovascular mortality and cardiovascular events in participants with established...

journal_title：BMJ open

authors： Schwingshackl L,Hoffmann G

更新日期：2014-04-19 00:00:00

abstract：OBJECTIVES:To investigate the impact of first eye and second eye cataract surgery on the level of physical activity undertaken by older adults with bilateral cataract. DESIGN:Prospective cohort study. SETTING:Three public ophthalmology clinics in Western Australia. PARTICIPANTS:Fifty-five older adults with bilateral...

journal_title：BMJ open

authors： Meuleners LB,Feng YR,Fraser M,Brameld K,Chow K

更新日期：2019-03-20 00:00:00

abstract：OBJECTIVES:Placenta or placental chorangioma could be the origin site of infantile haemangioma since they share various histochemical and genetic characteristics with placental vascular tissue. The aim of the current study was to investigate the association between chorangiomas and infantile haemangiomas in singleton a...

journal_title：BMJ open

authors： Sirotkina M,Douroudis K,Wahlgren CF,Westgren M,Papadogiannakis N

更新日期：2017-09-03 00:00:00

abstract：INTRODUCTION:Despite the strong relationship between smoking and health-related consequences, very few smokers quit. Heavy drinking is a significant risk factor for health consequences, and is implicated in persistent smoking and less success at quitting smoking. Self-efficacy (SE) to abstain from smoking is an importa...

journal_title：BMJ open

authors： Cohn A,Brandon T,Armeli S,Ehlke S,Bowers M

更新日期：2015-01-06 00:00:00

abstract：INTRODUCTION:Recurrent urinary tract infections (RUTIs) have a significant negative impact on quality of life and healthcare costs. To date, daily prophylactic antibiotics are the only treatment which have been shown to help prevent RUTIs. D-mannose is a type of sugar which is believed to inhibit bacterial adherence to...

journal_title：BMJ open

authors： Franssen M,Cook J,Robinson J,Williams N,Glogowska M,Yang Y,Allen J,Butler CC,Thomas N,Hay A,Moore M,Hayward G

更新日期：2021-01-13 00:00:00

abstract：OBJECTIVES:To evaluate the effect of social network influences on seasonal influenza vaccination uptake by healthcare workers. DESIGN:Cross-sectional, observational study. SETTING:A large secondary care NHS Trust which includes four hospital sites in Greater Manchester. PARTICIPANTS:Foundation doctors (FDs) working ...

journal_title：BMJ open

authors： Edge R,Keegan T,Isba R,Diggle P

更新日期：2019-08-30 00:00:00

abstract：INTRODUCTION:Poor treatment adherence and outcomes among patients with tuberculosis (TB) lead to drug resistance, and increased risk of morbidity, mortality and transmission of the disease in the community. Individual patient-level psychological and behavioural risk factors and structural-level social and health system...

journal_title：BMJ open

authors： Nagarajan K,Das B

更新日期：2019-05-19 00:00:00

abstract：INTRODUCTION:Bariatric surgery is increasingly recognised as an effective treatment option for subjects with type 2 diabetes and obesity; however, there is no conclusive evidence on the superiority of Roux-en-Y gastric bypass or sleeve gastrectomy. The Oseberg study was designed to compare the effects of gastric bypass...

journal_title：BMJ open

authors： Borgeraas H,Hjelmesæth J,Birkeland KI,Fatima F,Grimnes JO,Gulseth HL,Halvorsen E,Hertel JK,Hillestad TOW,Johnson LK,Karlsen TI,Kolotkin RL,Kvan NP,Lindberg M,Lorentzen J,Nordstrand N,Sandbu R,Seeberg KA,Seip B,Svane

更新日期：2019-06-04 00:00:00

abstract：OBJECTIVES:The clinical course and prognosis of follicular lymphoma (FL) are diverse and associated with the patient's immune response. We investigated the lymphocyte-to-monocyte ratio (LMR) and neutrophil-to-lymphocyte ratio (NLR) as prognostic factors in patients with FL, including those receiving radiotherapy. DESI...

journal_title：BMJ open

authors： Lee SF,Luque-Fernandez MA

更新日期：2017-11-03 00:00:00

abstract：OBJECTIVES:A significant proportion of cardiovascular disease (CVD) cannot be explained by well-known risk factors such as high cholesterol, hypertension and diabetes. One potential novel risk factor for CVD is asthma. We aimed to investigate the association between asthma and mortality due to CVD. DESIGN:Prospective ...

journal_title：BMJ open

authors： Strand LB,Tsai MK,Wen CP,Chang SS,Brumpton BM

更新日期：2018-05-31 00:00:00

abstract：OBJECTIVES:To investigate the feasibility of manual segmentation by users of different backgrounds in a previously developed multifeature computer-aided diagnosis (CADx) system to classify melanocytic and non-melanocytic skin lesions based on conventional digital photographic images. METHODS:In total, 347 conventional...

journal_title：BMJ open

authors： Chang WY,Huang A,Chen YC,Lin CW,Tsai J,Yang CK,Huang YT,Wu YF,Chen GS

更新日期：2015-05-03 00:00:00

abstract：INTRODUCTION:Mycobacterium tuberculosis (Mtb) is transmitted from person to person via airborne droplet nuclei. At the community level, Mtb transmission depends on the exposure venue, infectiousness of the tuberculosis (TB) index case and the susceptibility of the index case's social network. People living with HIV inf...

journal_title：BMJ open

authors： Zetola NM,Modongo C,Moonan PK,Click E,Oeltmann JE,Shepherd J,Finlay A

更新日期：2016-05-09 00:00:00

abstract：OBJECTIVES:To investigate the views and experiences of people who use codeine in order to describe the 'risk environment' capable of producing and reducing harm. DESIGN:This was a qualitative interview study. Psychological dependence on codeine was measured using the Severity of Dependence Scale. A cut-off score of 5 ...

journal_title：BMJ open

authors： Kinnaird E,Kimergård A,Jennings S,Drummond C,Deluca P

更新日期：2019-04-03 00:00:00

abstract：OBJECTIVES:To investigate known and suggested risk factors associated with cerebral palsy in a Swedish birth cohort, stratified by gestational age. SETTING:Information on all births between 1995 and 2014 in Skåne, the southernmost region in Sweden, was extracted from the national birth register. PARTICIPANTS:The coho...

journal_title：BMJ open

authors： Jöud A,Sehlstedt A,Källén K,Westbom L,Rylander L

更新日期：2020-08-07 00:00:00

abstract：OBJECTIVES:Our objective in this study is to evaluate the impact the Great Recession (2008-2014) had on self-perceived health in Spain. DESIGN:We use a longitudinal database (four waves of the Bank of Spain's Survey of Household Finances (2005, 2008, 2011 and 2014)) with repeated observations of the same individuals b...

journal_title：BMJ open

authors： Saez M,Vidiella-Martin J,Casasnovas GL

更新日期：2019-02-01 00:00:00