Abstract:
BACKGROUND:Pseudomonas aeruginosa is a Gram-negative bacteria responsible for infections in immunocompromised patients and is one of the most common causes of nosocomial infections particularly in intensive care and burn units. We aimed to investigate the population structure of P. aeruginosa strains isolated from patients at different hospital wards. METHODS:We analysed the possible presence of P. aeruginosa epidemic or endemic strains in hospitals of the selected region. A genotyping analysis was performed for P. aeruginosa isolates (n = 202) collected from patients of eleven hospitals in north-western Poland. Collections of P. aeruginosa were genotyped using pulsed-field gel electrophoresis (PFGE). Phenotypic screening for antibiotic susceptibility was performed for the common antimicrobial agents. RESULTS:Pseudomonas aeruginosa isolates were distributed among 116 different pulsotype groups. We identified 30 groups of clonally related strains, each containing from 2 to 17 isolates and typed the obtained 13 unique patterns, designated as A, D, E, J, K, M, N, Ó, P, T, X, AC, AD, and AH. The two largest clusters, D and E, contained 17 and 13 isolates, respectively. Strains of these groups were continuously isolated from patients at intensive care units and burn units, indicating transmission of these strains. CONCLUSIONS:In this study, we demonstrate the clonal relatedness of P. aeruginosa strains and their constant exchange in hospitals over a period of 15 months. The obtained results indicate a predominantly non-clonal structure of P. aeruginosa.
journal_name
BMC Infect Disjournal_title
BMC infectious diseasesauthors
Brzozowski M,Krukowska Ż,Galant K,Jursa-Kulesza J,Kosik-Bogacka Ddoi
10.1186/s12879-020-05404-wsubject
Has Abstractpub_date
2020-09-22 00:00:00pages
693issue
1issn
1471-2334pii
10.1186/s12879-020-05404-wjournal_volume
20pub_type
杂志文章,多中心研究abstract:BACKGROUND:The incidence of community-associated methicillin-resistant Staphylococcus aureus (MRSA) has risen dramatically in the U.S., particularly among children. Although Streptococcus pneumoniae colonization has been inversely associated with S. aureus colonization in unvaccinated children, this and other risk fact...
journal_title:BMC infectious diseases
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更新日期:2018-04-02 00:00:00
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pub_type: 杂志文章
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pub_type: 杂志文章
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journal_title:BMC infectious diseases
pub_type: 杂志文章
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更新日期:2010-05-20 00:00:00
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journal_title:BMC infectious diseases
pub_type: 杂志文章
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journal_title:BMC infectious diseases
pub_type: 杂志文章
doi:10.1186/1471-2334-10-288
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journal_title:BMC infectious diseases
pub_type: 杂志文章
doi:10.1186/s12879-019-3815-8
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pub_type: 杂志文章,评审
doi:10.1186/1471-2334-14-480
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