Protocol for a cluster-randomised non-inferiority trial of one versus two doses of ivermectin for the control of scabies using a mass drug administration strategy (the RISE study).

abstract：OBJECTIVES:Record review is the most used method to quantify patient safety. We systematically reviewed the reliability and validity of adverse event detection with record review. DESIGN:A systematic review of the literature. METHODS:We searched PubMed, EMBASE, CINAHL, PsycINFO and the Cochrane Library and from their...

journal_title：BMJ open

authors： Hanskamp-Sebregts M,Zegers M,Vincent C,van Gurp PJ,de Vet HC,Wollersheim H

更新日期：2016-08-22 00:00:00

abstract：OBJECTIVES:Given many countries' ageing populations, policymakers must consider how to mitigate or reduce health problems associated with old age, within budgetary constraints. Evidence of use of digital technology in delaying the onset of illness and reducing healthcare service use is mixed, with no clear consensus as...

journal_title：BMJ open

authors： Clarke CS,Round J,Morris S,Kharicha K,Ford J,Manthorpe J,Iliffe S,Goodman C,Walters K

更新日期：2017-07-21 00:00:00

abstract：PURPOSE:To design a linked hospital database using administrative and clinical information to describe associations that predict infectious diseases outcomes, including long-term mortality. PARTICIPANTS:A retrospective cohort of Townsville Hospital inpatients discharged with an International Classification of Diseases...

journal_title：BMJ open

authors： Eisen DP,McBryde ES,Vasanthakumar L,Murray M,Harings M,Adegboye O

更新日期：2020-03-18 00:00:00

abstract：OBJECTIVES:This study aims to examine the tracking and predictability of physical activity in old age from overall physical activity and participation in sport, recreational activity and walking in mid-life. DESIGN:Prospective population-based cohort study. SETTING:British Regional Heart Study participants recruited ...

journal_title：BMJ open

authors： Aggio D,Papacosta O,Lennon L,Whincup P,Wannamethee G,Jefferis BJ

更新日期：2017-09-21 00:00:00

abstract：OBJECTIVES:Identifying the issues and concerns that matter most to burns survivors can be challenging. For a number of reasons, but mainly relating to patient empowerment, some of the most pressing concerns patients may have during a clinical encounter may not naturally be the focal point of that encounter. The Patient...

journal_title：BMJ open

authors： Gibson JAG,Yarrow J,Brown L,Evans J,Rogers SN,Spencer S,Shokrollahi K

更新日期：2019-12-30 00:00:00

abstract：INTRODUCTION:Many types of audits are commonly used in hospital care to promote quality improvements. However, the evidence on the effectiveness of audits is mixed. The objectives of this proposed realist review are (1) to understand how and why audits might, or might not, work in terms of delivering the intended outco...

journal_title：BMJ open

authors： Hut-Mossel L,Welker G,Ahaus K,Gans R

更新日期：2017-06-14 00:00:00

abstract：OBJECTIVE:Self-reported recall data are often used in wireless phone epidemiological studies, which in turn are used to indicate relative risk of health outcomes from extended radiofrequency exposure. We sought to explain features commonly observed in wireless phone recall data and to improve analytical procedures. SE...

journal_title：BMJ open

authors： Redmayne M,Smith E,Abramson MJ

更新日期：2012-09-04 00:00:00

abstract：OBJECTIVES:The local care and treatment of liver disease (LOCATE) intervention embedded specialist liver nurses in general practitioner (GP) practices to improve the identification of progressive liver disease, enabling earlier intervention. This current process evaluation examines GP practice staffs' perceptions of th...

journal_title：BMJ open

authors： Reinson T,Bradbury K,Moore M,Sheron N

更新日期：2019-05-22 00:00:00

abstract：OBJECTIVE:Cardiac disease in pregnancy is a leading cause of maternal death in high-income countries. Evidence-based guidelines to assist in planning and managing the healthcare of affected women is lacking. The objective of this research was to produce the first qualitative metasynthesis of the experiences of pregnant...

journal_title：BMJ open

authors： Dawson AJ,Krastev Y,Parsonage WA,Peek M,Lust K,Sullivan EA

更新日期：2018-09-28 00:00:00

abstract：INTRODUCTION:People with intellectual disability (ID) are more likely to experience loneliness and have smaller social networks, which increases vulnerability to depression. Befriending may reduce depressive symptoms in other populations, but randomised controlled trials (RCTs) have not been carried out in this populat...

journal_title：BMJ open

authors： Ali A,Mckenzie E,Hassiotis A,Priebe S,Lloyd-Evans B,Omar R,Jones R,Panca M,Fernandez V,Finning S,Moore S,O'Connor D,Roe C,King M

更新日期：2020-06-21 00:00:00

abstract：INTRODUCTION:Multimorbidity (MM) refers to the coexistence of two or more chronic conditions within one person, where no one condition is considered primary. As populations age and healthcare provision improves, MM is becoming increasingly common and poses a challenge to the single morbidity approach to illness managem...

journal_title：BMJ open

authors： Slattery BW,O'Connor L,Haugh S,Dwyer CP,O'Higgins S,Caes L,Egan J,McGuire BE

更新日期：2017-01-18 00:00:00

abstract：OBJECTIVE:This study aimed to identify body mass index (BMI) trajectories and their predictors in Australian children by their maternal immigrant status. METHODS:Data on 4142 children aged 2-3 years were drawn from the birth cohort of the Longitudinal Study of Australian Children. BMI was calculated according to the I...

journal_title：BMJ open

authors： Zulfiqar T,Burns RA,D'Este C,Strazdins L

更新日期：2019-07-09 00:00:00

abstract：OBJECTIVES:This study aimed to explore barriers to accessing care, if any, among people living with HIV/AIDS (PLHA) in two districts of Bihar. We also aimed to assess attitudes towards PLHA among healthcare providers and community members. DESIGN:This qualitative study used an exploratory study design through thematic...

journal_title：BMJ open

authors： Nair M,Kumar P,Pandey S,Harshana A,Kazmi S,Moreto-Planas L,Burza S

更新日期：2019-11-25 00:00:00

abstract：INTRODUCTION:Premature infants are particularly vulnerable to brain injuries with associated cognitive and behavioural deficits. The worldwide first randomised interventional multicentre trial investigating the neuroprotective effects of erythropoietin (entitled 'Does erythropoietin improve outcome in very preterm infa...

journal_title：BMJ open

authors： Wehrle FM,Held U,O'Gorman RT,Disselhoff V,Schnider B,Fauchère JC,Hüppi P,Latal B,Hagmann CF

更新日期：2018-04-24 00:00:00

abstract：INTRODUCTION:Chronic kidney disease is a serious and a frequent disease associated with a high risk of morbi-mortality. Although several risk factors have already been well addressed, mostly diabetes and hypertension, many remain underappreciated, such as chronic exposure to air pollution. METHODS AND ANALYSIS:We will...

journal_title：BMJ open

authors： Hamroun A,Camier A,Bigna JJ,Glowacki F

更新日期：2021-01-17 00:00:00

abstract：INTRODUCTION:Community-based interventions have been found to effectively increase the implementation of alcohol management practices and reduce excessive alcohol use and alcohol-related harm at sports clubs. However, once implementation support ceases there may be a reduction in such intervention effects. Thus, ongoin...

journal_title：BMJ open

authors： McFadyen T,Wolfenden L,Kingsland M,Tindall J,Rowland B,Sherker S,Gillham K,Heaton R,Clinton-McHarg T,Lecathelinais C,Brooke D,Wiggers J

更新日期：2018-01-23 00:00:00

abstract：OBJECTIVES:This evidence review was conducted to understand how and why workforce development interventions can improve the skills and care standards of support workers in older people's services. DESIGN:Following recognised realist synthesis principles, the review was completed by (1) development of an initial progra...

journal_title：BMJ open

authors： Williams L,Rycroft-Malone J,Burton CR,Edwards S,Fisher D,Hall B,McCormack B,Nutley SM,Seddon D,Williams R

更新日期：2016-08-26 00:00:00

abstract：INTRODUCTION:Financial toxicity (FT) is a well-recognised problem in oncology. US-based studies have shown that: (a) cancer patients have a 2.7 times risk of bankruptcy; (b) patients who declare bankruptcy have a 79% greater hazard of death; (c) financial burden significantly impairs quality of life (QoL) and (d) reduc...

journal_title：BMJ open

authors： Riva S,Bryce J,De Lorenzo F,Del Campo L,Di Maio M,Efficace F,Frontini L,Giannarelli D,Gitto L,Iannelli E,Jommi C,Montesarchio V,Traclò F,Vaccaro CM,Gallo C,Perrone F

更新日期：2019-09-09 00:00:00

abstract：OBJECTIVES:To simplify our previous risk score for predicting the in-hospital mortality risk in patients with non-ST-segment elevation myocardial infarction (NSTEMI) by dropping laboratory data. DESIGN:Prospective cohort. SETTING:Multicentre, 108 hospitals across three levels in China. PARTICIPANTS:A total of 5775 p...

journal_title：BMJ open

authors： Song C,Fu R,Li S,Yang J,Wang Y,Xu H,Gao X,Liu J,Liu Q,Wang C,Dou K,Yang Y

更新日期：2019-09-12 00:00:00

abstract：INTRODUCTION:Although studies showed that physical activity (PA) and sedentary behaviour (SB) were associated with cardiometabolic risk factors and cognitive function, both independent and combined associations among them are inconsistent. Cardiometabolic risk factors are also associated with cognitive function, but re...

journal_title：BMJ open

authors： Lv Y,Cai L,Gui Z,Zeng X,Tan M,Wan N,Lai L,Lu S,Tan W,Chen Y

更新日期：2019-10-31 00:00:00

abstract：OBJECTIVE:To examine the effects of a consultant-led, community-based chronic obstructive pulmonary disease (COPD) service, based in a highly deprived area on emergency hospital admissions. DESIGN:A longitudinal matched controlled study using difference-in-differences analysis to compare the change in outcomes in the ...

journal_title：BMJ open

authors： Saini P,Rose T,Downing J,Matata B,Pilsworth S,Pemberton A,Comerford T,Wilson K,Shaw M,Harper LM,Daras K,Barr B

更新日期：2020-05-27 00:00:00

abstract：OBJECTIVE:To evaluate the effects of intravenous fluid bolus compared to maintenance intravenous fluids alone as part of immediate emergency care in children with severe febrile illness and signs of impaired circulation in low-income settings. DESIGN:Systematic review of randomised controlled trials (RCTs), and observ...

journal_title：BMJ open

authors： Opiyo N,Molyneux E,Sinclair D,Garner P,English M

更新日期：2014-04-30 00:00:00

abstract：INTRODUCTION:Providing smoking cessation treatment is an important intervention for tuberculosis (TB) patients. Mobile technologies, such as smartphone applications, have shown promising potential. However, there are few effective applications that could support TB patients in their efforts to quit smoking. To address ...

journal_title：BMJ open

authors： Lin H,Lin Y,Zheng Y,Liu Z,Chang C

更新日期：2019-12-02 00:00:00

abstract：INTRODUCTION:In current practice, probands are asked to inform relatives about the possibility of predictive DNA testing when a pathogenic variant causing an inherited cardiac condition (ICC) is identified. Previous research on the uptake of genetic counselling and predictive DNA testing in relatives suggests that not ...

journal_title：BMJ open

authors： van den Heuvel LM,Hoedemaekers YM,Baas AF,van Tintelen JP,Smets EMA,Christiaans I

更新日期：2019-07-09 00:00:00

abstract：OBJECTIVE:To determine the feasibility of a randomised controlled trial (RCT) assessing the effects of an experience-based website as a resource for the self-management of chronic asthma. DESIGN AND SETTING:Feasibility, single-blind RCT in 2 regions of England. Randomisation used computer-generated random number seque...

journal_title：BMJ open

authors： Newhouse N,Martin A,Jawad S,Yu LM,Davoudianfar M,Locock L,Ziebland S,Powell J

更新日期：2016-12-28 00:00:00

abstract：OBJECTIVES:Defects in the human thyroid peroxidase (TPO) gene are reported to be one of the causes of congenital hypothyroidism (CH) due to dyshormonogenesis. The aim of this study was to examine the TPO mutation spectrum and prevalence among patients with CH in the Guangxi Zhuang Autonomous Region of China and to defi...

journal_title：BMJ open

authors： Fu C,Xie B,Zhang S,Wang J,Luo S,Zheng H,Su J,Hu X,Chen R,Fan X,Luo J,Gu X,Chen S

更新日期：2016-05-12 00:00:00

abstract：INTRODUCTION:Schools are promising settings for physical activity promotion; however, they are complex and adaptive systems that can influence the quality of programme implementation. This paper presents an evaluation of a school-based running programme (Marathon Kids). The aims of this study are (1) to identify the pr...

journal_title：BMJ open

authors： Chalkley AE,Routen AC,Harris JP,Cale LA,Gorely T,Sherar LB

更新日期：2018-05-14 00:00:00

abstract：INTRODUCTION:Gyejibongneyong-hwan (GBH), also known as Guizhi Fuling formula, and is widely used for uterine fibroids in East Asian countries. Many clinical trials assessing the efficacy and safety of GBH formula for the treatment of dysmenorrhoea have been reported. This review will assess the clinical evidence for an...

journal_title：BMJ open

authors： Lee JA,Park S,Jung J,Jun JH,Choi J,Lee MS

更新日期：2016-09-28 00:00:00

abstract：OBJECTIVE:To explore patients' experience of receiving pain relief injection for suspected hip fracture from paramedics at the location of the injury. DESIGN:Qualitative interviews within a feasibility trial about an alternative to routine prehospital pain management for patients with suspected hip fracture. SETTING:...

journal_title：BMJ open

authors： Evans BA,Brown A,Fegan G,Ford S,Guy K,Jones J,Jones S,Keen L,Khanom A,Longo M,Pallister I,Rees N,Russell IT,Seagrove AC,Watkins A,Snooks H

更新日期：2019-12-19 00:00:00

abstract：INTRODUCTION:Short-term psychodynamic psychotherapy (STPP) is an empirically supported treatment that is often used to treat depression. However, it is largely unclear if certain subgroups of depressed patients can benefit specifically from this treatment method. We describe the protocol for a systematic review and met...

journal_title：BMJ open

authors： Driessen E,Abbass AA,Barber JP,Connolly Gibbons MB,Dekker JJM,Fokkema M,Fonagy P,Hollon SD,Jansma EP,de Maat SCM,Town JM,Twisk JWR,Van HL,Weitz E,Cuijpers P

更新日期：2018-02-20 00:00:00