Refused and referred-persistent stigma and discrimination against people living with HIV/AIDS in Bihar: a qualitative study from India.

abstract：OBJECTIVES:Multimorbidity, defined as the presence of 2 or more chronic medical conditions in an individual, is associated with poorer health outcomes. Several multimorbidity measures exist, and the challenge is to decide which to use preferentially in predicting health outcomes. The study objective was to compare the ...

journal_title：BMJ open

authors： Wallace E,McDowell R,Bennett K,Fahey T,Smith SM

更新日期：2016-09-20 00:00:00

abstract：OBJECTIVES:Two oral targeted therapies, gefitinib and erlotinib, were first approved and then launched into the market for treatment of late-stage non-small cell lung cancer (NSCLC) in Taiwan in 2003 and 2006, respectively. The aim of this study were to determine the trends in lung cancer burden and examine changes in ...

journal_title：BMJ open

authors： Hsu JC,Wei CF,Yang SC,Lin PC,Lee YC,Lu CY

更新日期：2020-05-10 00:00:00

abstract：OBJECTIVES:Mortality has declined in people with HIV infection, subsequent to the improved access to antiretroviral therapy (ART). We assessed the incidence and determinants of mortality among patients with HIV-1 infection who were started on ART in a referral treatment centre for HIV infection in Yaounde, Cameroon. D...

journal_title：BMJ open

authors： Poka-Mayap V,Pefura-Yone EW,Kengne AP,Kuaban C

更新日期：2013-07-13 00:00:00

abstract：OBJECTIVE:To determine factors and outcomes associated with ultra-early surgery for poor-grade aneurysmal subarachnoid haemorrhage (aSAH). DESIGN:A multicentre retrospective analysis, observational study. SETTING:High-volume teaching hospitals (more than 150 aSAH cases per year). PARTICIPANTS:118 patients with World...

journal_title：BMJ open

authors： Zhao B,Zhao Y,Tan X,Cao Y,Wu J,Zhong M,Wang S

更新日期：2015-04-15 00:00:00

abstract：OBJECTIVES:This study investigated self-perception of overall health (SPH) and quality of life (QoL) at onset and after 3, 6 and 12 months of fitness club membership. Also, we compared SPH and QoL between those who reported regular use of the fitness club (≥2 exercise sessions/week the last month) with those who did no...

journal_title：BMJ open

authors： Heiestad H,Gjestvang C,Haakstad LAH

更新日期：2020-06-07 00:00:00

abstract：INTRODUCTION:Opioids prescribed after surgery accounted for 5% of the 191 million opioid prescriptions filled in 2017. Approximately 80% of the opioid pills prescribed by surgical care providers remain unused, leaving a substantial number of opioids available for non-medical use. We developed a multi-component interven...

journal_title：BMJ open

authors： Stulberg JJ,Schäfer WLA,Shallcross ML,Lambert BL,Huang R,Holl JL,Bilimoria KY,Johnson JK

更新日期：2019-06-03 00:00:00

abstract：OBJECTIVE:Multimorbidity in patients with heart failure (HF) results in poor prognosis and is an increasing public health concern. We aim to examine the effect of multimorbidity focusing on type 2 diabetes mellitus (T2DM) and chronic kidney disease (CKD) on all-cause and cardiovascular disease (CVD)-specific mortality ...

journal_title：BMJ open

authors： Kaur P,Saxena N,You AX,Wong RCC,Lim CP,Loh SY,George PP

更新日期：2018-05-20 00:00:00

abstract：INTRODUCTION:Expectant mothers in low-income and middle-income countries often lack access to vital information about pregnancy, preparation for birth and best practices when caring for their newborn. Innovative solutions are needed to bridge this knowledge gap and dramatically improve maternal and neonatal health in t...

journal_title：BMJ open

authors： Su Y,Yuan C,Zhou Z,Heitner J,Campbell B

更新日期：2016-08-10 00:00:00

abstract：INTRODUCTION:Idiopathic Environmental Intolerance (IEI) attributed to electromagnetic fields (EMF) refers to self-reported sensitivity mainly characterised by the attribution of non-specific physical symptoms to low-level EMF exposure emitted from sources such as mobile phones. Scientific studies have not provided evid...

journal_title：BMJ open

authors： Bogers RP,Bolte JF,Houtveen JH,Lebret E,van Strien RT,Schipper CM,Alkadhimi M,Baliatsas C,van Kamp I

更新日期：2013-08-29 00:00:00

abstract：OBJECTIVES AND DESIGN:We identified a novel TRIM59 gene, as an early signal transducer in two (SV40Tag and Ras) oncogene pathways in murine prostate cancer (CaP) models. We explore its clinical applications as a multitumour marker detecting early tumorigenesis by immunohistochemistry (IHC). SETTING AND PARTICIPANTS:88...

journal_title：BMJ open

authors： Khatamianfar V,Valiyeva F,Rennie PS,Lu WY,Yang BB,Bauman GS,Moussa M,Xuan JW

更新日期：2012-10-08 00:00:00

abstract：INTRODUCTION:Patients presenting with acute intracerebral haemorrhage are at a high risk of exhibiting haematoma expansion, a phenomenon that can significantly worsen long-term functioning. Numerous clinical and radiological factors are associated with expansion. In a bid to better select patients at increased risk of ...

journal_title：BMJ open

authors： Yogendrakumar V,Moores M,Sikora L,Ramsay T,Fergusson DA,Dowlatshahi D

更新日期：2019-01-21 00:00:00

abstract：OBJECTIVES:To investigate the association between the difficulty in hospital acceptance at the scene by emergency medical service (EMS) personnel and prehospital demographic factors and reasons for EMS calls. DESIGN:A retrospective, observational study. SETTING:Osaka City, Japan. PARTICIPANTS:A total of 100 649 pati...

journal_title：BMJ open

authors： Katayama Y,Kitamura T,Kiyohara K,Iwami T,Kawamura T,Hayashida S,Yoshiya K,Ogura H,Shimazu T

更新日期：2016-10-26 00:00:00

abstract：OBJECTIVE:To evaluate accuracy of content and readability level of English Wikipedia articles on cardiovascular diseases, using quality and readability tools. METHODS:Wikipedia was searched on the 6 October 2013 for articles on cardiovascular diseases. Using a modified DISCERN (DISCERN is an instrument widely used in ...

journal_title：BMJ open

authors： Azer SA,AlSwaidan NM,Alshwairikh LA,AlShammari JM

更新日期：2015-10-06 00:00:00

abstract：OBJECTIVES:To evaluate the cost-effectiveness of immediate treatment with ranibizumab in patients with neovascular age-related macular degeneration (nAMD) with good (better than 6/12) starting visual acuity compared with current UK clinical guidance of waiting until vision falls below 6/12 to begin treatment, using rea...

journal_title：BMJ open

authors： Butt T,Lee A,Lee C,Tufail A,UK AMD EMR Study Group.

更新日期：2015-05-05 00:00:00

abstract：OBJECTIVES:Novel therapeutics are an important part of ophthalmologists' armamentarium, and the risks and benefits of these therapies must be carefully evaluated. We sought to quantify the characteristics of the pivotal clinical trials supporting the regulatory approval of new ophthalmic drugs and medical devices. DES...

journal_title：BMJ open

authors： Hwang J,Hwang TJ,Ciolino JB

更新日期：2015-06-04 00:00:00

abstract：INTRODUCTION:Epilepsy is a common neurological condition affecting between 3% and 3.5% of the Australian population at some point in their lifetime. The effective management of chronic and complex conditions such as epilepsy requires person-centred and coordinated care across sectors, from primary to tertiary healthcar...

journal_title：BMJ open

authors： Rapport F,Hutchinson K,Herkes GK,Bleasel A,Nikpour A,Ryder T,Wong C,Bartley M,Ireland C,Coleman H,Todd L,Groot W,Kerr M,Vagholkar S,Shears G,Braithwaite J

更新日期：2021-01-25 00:00:00

abstract：OBJECTIVES:To assess how the quality of metronome-guided cardiopulmonary resuscitation (CPR) was affected by the chest compression rate familiarised by training before the performance and to determine a possible mechanism for any effect shown. DESIGN:Prospective crossover trial of a simulated, one-person, chest-compre...

journal_title：BMJ open

authors： Bae J,Chung TN,Je SM

更新日期：2016-02-12 00:00:00

abstract：INTRODUCTION:Stroke is among the leading causes of death and disability worldwide. Poststroke cognitive impairment is a common sequela of stroke. The burden of cognitive impairment poststroke has significant impacts on the individual poststroke, their family and wider society. Despite the prevalence and associated burd...

journal_title：BMJ open

authors： O Donoghue M,Boland P,Galvin R,Coote S,Hayes S

更新日期：2019-11-07 00:00:00

abstract：OBJECTIVE:We aimed to determine the key predictors of perinatal deaths using machine learning models compared with the logistic regression model. DESIGN:A secondary data analysis using the Kilimanjaro Christian Medical Centre (KCMC) Medical Birth Registry cohort from 2000 to 2015. We assessed the discriminative abilit...

journal_title：BMJ open

authors： Mboya IB,Mahande MJ,Mohammed M,Obure J,Mwambi HG

更新日期：2020-10-19 00:00:00

abstract：OBJECTIVE:Hepatitis B reactivation (HBr) is strongly associated with rituximab therapy. Guidelines advise hepatitis B screening and use of preventive nucleoside analogue (NA) in patients at risk. In this study, we examined screening trends, post-screening interventions and outcomes in patients receiving rituximab in li...

journal_title：BMJ open

authors： Haider M,Flocco G,Lopez R,Carey W

更新日期：2020-12-15 00:00:00

abstract：OBJECTIVES:The main purpose of the present study was to explore the associations between sleep quality and insufficient physical activity. DESIGN:Cross-sectional. SETTING:Faculties in Croatia. PARTICIPANTS:2100 university students (1049 men and 1051 women) aged 18-24 years were recruited. PRIMARY OUTCOME:To assess ...

journal_title：BMJ open

authors： Štefan L,Sporiš G,Krističević T,Knjaz D

更新日期：2018-07-13 00:00:00

abstract：INTRODUCTION:Clinical decision-making is a complex process. Patient preference information regarding desirable health states should inform treatment and is critical to agreeing on goals of therapy. Cystic fibrosis (CF) is a common, inheritable multisystem disorder for which the major manifestation is progressive, chron...

journal_title：BMJ open

authors： McLeod C,Norman R,Schultz A,Mascaro S,Webb S,Snelling T

更新日期：2019-08-18 00:00:00

abstract：INTRODUCTION:There is a growing proportion of population aged 65 years and older in low-income and middle-income countries. In Malaysia, this proportion is predicted to increase from 5.1% in 2010 to more than 15.4% by 2050. Cognitive ageing and dementia are global health priorities. However, risk factors and disease as...

journal_title：BMJ open

authors： Mohan D,Stephan BC,Allotey P,Jagger C,Pearce M,Siervo M,Reidpath DD

更新日期：2017-01-19 00:00:00

abstract：OBJECTIVES:Conduct a feasibility study on the effect of menstrual hygiene on schoolgirls' school and health (reproductive/sexual) outcomes. DESIGN:3-arm single-site open cluster randomised controlled pilot study. SETTING:30 primary schools in rural western Kenya, within a Health and Demographic Surveillance System. ...

journal_title：BMJ open

authors： Phillips-Howard PA,Nyothach E,Ter Kuile FO,Omoto J,Wang D,Zeh C,Onyango C,Mason L,Alexander KT,Odhiambo FO,Eleveld A,Mohammed A,van Eijk AM,Edwards RT,Vulule J,Faragher B,Laserson KF

更新日期：2016-11-23 00:00:00

abstract：INTRODUCTION:HIV-associated neurocognitive disorder (HAND) may affect 30%-50% of people ageing with HIV. HAND may increase stress and anxiety, and impede coping. Psychosocial group therapy may ameliorate HAND's symptoms, yet the ideal intervention is unclear. This protocol outlines a pilot randomised controlled trial (...

journal_title：BMJ open

authors： Eaton AD,Walmsley SL,Craig SL,Rourke SB,Sota T,McCullagh JW,Fallon BA

更新日期：2019-10-31 00:00:00

abstract：OBJECTIVE:To identify factors associated with health literacy in multimorbid patients. DESIGN:A nationwide cross-sectional study in Switzerland. Univariate and multivariate linear regressions were calculated to identify variables associated with health literacy. A multiple imputation approach was used to deal with mis...

journal_title：BMJ open

authors： N'Goran AA,Pasquier J,Deruaz-Luyet A,Burnand B,Haller DM,Neuner-Jehle S,Zeller A,Streit S,Herzig L,Bodenmann P

更新日期：2018-02-13 00:00:00

abstract：INTRODUCTION:Depression and alcohol use disorders are international public health priorities for which there is a substantial treatment gap. Brief mental health interventions delivered by lay health workers in primary care services may reduce this gap. There is limited economic evidence assessing the cost-effectiveness...

journal_title：BMJ open

authors： Mutyambizi-Mafunda V,Myers B,Sorsdahl K,Lund C,Naledi T,Cleary S

更新日期：2019-05-14 00:00:00

abstract：OBJECTIVES:To systematically assess registration details of ongoing randomised controlled trials (RCTs) targeting 10 common chronic conditions and registered at ClinicalTrials.gov and to determine the prevalence of (1) trial records excluding patients with concomitant chronic condition(s) and (2) those specifically tar...

journal_title：BMJ open

authors： Buffel du Vaure C,Dechartres A,Battin C,Ravaud P,Boutron I

更新日期：2016-09-27 00:00:00

abstract：OBJECTIVES:The integration of community pharmacy services (CPSs) into primary care practice can be enhanced by assessing (and further addressing) the elements that enable (ie, facilitators) or hinder (ie, barriers) the implementation of such CPSs. These elements have been widely researched from the perspective of pharm...

journal_title：BMJ open

authors： Hossain LN,Fernandez-Llimos F,Luckett T,Moullin JC,Durks D,Franco-Trigo L,Benrimoj SI,Sabater-Hernández D

更新日期：2017-09-05 00:00:00

abstract：OBJECTIVES:Previous qualitative research investigating the experiences of women diagnosed with gestational diabetes (GD) has provided important insights into the development of behaviour change interventions. However, these studies often lack a theoretical underpinning. This study explored the use of the capability, op...

journal_title：BMJ open

authors： Boyd J,McMillan B,Easton K,Delaney B,Mitchell C

更新日期：2020-08-04 00:00:00