Abstract:
BACKGROUND:The application of neuroendoscopy in intraventricular hemorrhage (IVH) has attracted more and more attention in recent years. Studies have shown that the use of neuroendoscopy for IVH evacuation has advantages over external ventricular drainage (EVD) alone. However, the cases of most current research are small and all of them are retrospective studies. The aim of this study is to explore the prognosis of patients with moderate to severe IVH who undergo endoscopic IVH evacuation surgery versus those who undergo EVD alone. METHODS:The study is a prospective, randomized, controlled, multi-center clinical trial. Nine hundred and fifty-six subjects with moderate to severe IVH across four tertiary hospitals in China will be randomly assigned (1:1) to receive either endoscopic IVH evacuation surgery or EVD. The primary objective is to compare patients' survival rate at 12 months after surgery. DISCUSSION:The trial is designed to investigate the prognostic benefits of endoscopic IVH evacuation surgery for patients with moderate to severe IVH. Currently, it has never been investigated in a prospective randomized controlled clinical trial. TRIAL REGISTRATION:ClinicalTrials.gov, NCT04037267 . Registered on 26 July 2019.
journal_name
Trialsjournal_title
Trialsauthors
Zhu J,Tang C,Cong Z,Yang J,Cai X,Liu Y,Ma Cdoi
10.1186/s13063-020-04560-3subject
Has Abstractpub_date
2020-07-13 00:00:00pages
640issue
1issn
1745-6215pii
10.1186/s13063-020-04560-3journal_volume
21pub_type
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