Early Phase of the COVID-19 Outbreak in Hungary and Post-Lockdown Scenarios.

abstract：:Viroids are small non-capsidated non-coding RNA replicons that utilize host factors for efficient propagation and spread through the entire plant. They can incite specific disease symptoms in susceptible plants. To better understand viroid-plant interactions, we employed microarray analysis to observe the changes of g...

journal_title：Viruses

authors： Więsyk A,Iwanicka-Nowicka R,Fogtman A,Zagórski-Ostoja W,Góra-Sochacka A

更新日期：2018-05-15 00:00:00

abstract：:Significantly higher numbers of human infections with H5N1 virus have occurred in Indonesia and Egypt, compared with other affected areas, and it is speculated that there are specific viral factors for human infection with avian H5N1 viruses in these locations. We previously showed PB2-K526R is present in 80% of Indon...

journal_title：Viruses

authors： Wang P,Song W,Mok BW,Zheng M,Lau SY,Liu S,Chen P,Huang X,Liu H,Cremin CJ,Chen H

更新日期：2019-03-22 00:00:00

abstract：:The mouse mammary tumor virus (MMTV) Pr77Gag polypeptide is an essential retroviral structural protein without which infectious viral particles cannot be formed. This process requires specific recognition and packaging of dimerized genomic RNA (gRNA) by Gag during virus assembly. Most of the previous work on retrovira...

journal_title：Viruses

authors： Chameettachal A,Pillai VN,Ali LM,Pitchai FNN,Ardah MT,Mustafa F,Marquet R,Rizvi TA

更新日期：2018-06-18 00:00:00

abstract：:Tailoring public health responses to growing HIV transmission clusters depends on accurately mapping the risk network through which it spreads and identifying acute infections that represent the leading edge of cluster growth. HIV transmission links, especially those involving persons with acute HIV infection (AHI), c...

journal_title：Viruses

authors： Campbell EM,Patala A,Shankar A,Li JF,Johnson JA,Westheimer E,Gay CL,Cohen SE,Switzer WM,Peters PJ

更新日期：2020-01-27 00:00:00

abstract：:We developed an innovative strategy to induce a cytotoxic T cell (CTL) immune response against protein antigens of choice. It relies on the production of exosomes, i.e., nanovesicles spontaneously released by all cell types. We engineered the upload of huge amounts of protein antigens upon fusion with an anchoring pro...

journal_title：Viruses

authors： Di Bonito P,Ridolfi B,Columba-Cabezas S,Giovannelli A,Chiozzini C,Manfredi F,Anticoli S,Arenaccio C,Federico M

更新日期：2015-03-09 00:00:00

abstract：:Nasopharyngeal cancer (NPC) is associated with Epstein Barr virus (EBV) infection. However different viral strains have been implicated in NPC worldwide. This study aimed to detect and characterize EBV in patients diagnosed with NPC in Ghana. A total of 55 patients diagnosed with NPC by CT scan and endoscopy were age-...

journal_title：Viruses

authors： Ayee R,Ofori MEO,Tagoe EA,Languon S,Searyoh K,Armooh L,Bilson-Amoah E,Baidoo K,Kitcher E,Wright E,Quaye O

更新日期：2020-07-16 00:00:00

abstract：:The chikungunya virus (CHIKV) is an emerging pathogen with widespread distribution in regions of Africa, India, and Asia that threatens to spread into temperate climates with the introduction of its major vector, Aedes albopictus. CHIKV causes a disease frequently misdiagnosed as dengue fever, with potentially life-th...

journal_title：Viruses

authors： Mishra P,Furey C,Balaraman V,Fraser MJ

更新日期：2016-06-10 00:00:00

abstract：:The development of oncolytic viruses has led to an emerging new class of cancer therapeutics. Although the safety profile has been encouraging, the transition of oncolytic viruses to the clinical setting has been a slow process due to modifications. Therefore, a new generation of more potent oncolytic viruses needs to...

journal_title：Viruses

authors： Yuan M,Webb E,Lemoine NR,Wang Y

更新日期：2016-03-07 00:00:00

abstract：:In the midst of the SARS-CoV-2/Covid-19 outbreak the need for research into, and development of, antiviral agents is brought into sharp focus worldwide for scientists, governments and the public alike [...]. ...

journal_title：Viruses

authors： Adamson CS

更新日期：2020-04-07 00:00:00

abstract：:Metagenomics studies have accelerated the discovery of novel or divergent viruses of the honey bee. However, most of these studies predominantly focused on RNA viruses, and many suffer from the relatively low abundance of viral nucleic acids in the samples (i.e., compared to that of the host). Here, we explored the vi...

journal_title：Viruses

authors： Gebremedhn H,Deboutte W,Schoonvaere K,Demaeght P,De Smet L,Amssalu B,Matthijnssens J,de Graaf DC

更新日期：2020-10-27 00:00:00

abstract：:Hepatitis C virus (HCV) is a leading cause of chronic liver disease, including chronic hepatitis, fibrosis, cirrhosis, and hepatocellular carcinoma. Hepatitis C infection associates with lipid and lipoprotein metabolism disorders such as hepatic steatosis, hypobetalipoproteinemia, and hypocholesterolemia. Furthermore,...

journal_title：Viruses

authors： Felmlee DJ,Hafirassou ML,Lefevre M,Baumert TF,Schuster C

更新日期：2013-05-23 00:00:00

abstract：:Bacterial infections pose a challenge to human health and burden the health care system, especially with the spread of antibiotic-resistant populations. To provide effective treatment and improved prognosis, effective diagnostic methods are of great importance. Here we present phage-mediated molecular detection (PMMD)...

journal_title：Viruses

authors： Malagon F,Estrella LA,Stockelman MG,Hamilton T,Teneza-Mora N,Biswas B

更新日期：2020-04-11 00:00:00

abstract：:The environmental factors that lead to the reactivation of human T cell leukemia virus type-1 (HTLV-I) in latently infected T cells in vivo remain unknown. It has been previously shown that heat shock (HS) is a potent inducer of HTLV-I viral protein expression in long-term cultured cell lines. However, the precise HTL...

journal_title：Viruses

authors： Kunihiro M,Fujii H,Miyagi T,Takahashi Y,Tanaka R,Fukushima T,Ansari AA,Tanaka Y

更新日期：2016-07-11 00:00:00

abstract：:H1N1 swine influenza viruses (SIV) are prevalent in pigs globally, and occasionally emerge in humans, which raises concern about their pandemic threats. To stimulate hemagglutination (HA) of A/Swine/Guangdong/LM/2004 (H1N1) (SW/GD/04) antibody response, eukaryotic expression plasmid pCI-neo-HA was constructed and used...

journal_title：Viruses

authors： Liu Y,Li H,Xue Y,Zhao S,Li C,Qu L,Zhang Y,Liu M

更新日期：2017-08-08 00:00:00

abstract：:Ringspot symptoms in European mountain ash (Sorbus aucuparia L.), fig mosaic, rose rosette, raspberry leaf blotch, pigeonpea sterility mosaic (Cajanus cajan) and High Plains disease of maize and wheat were found to be associated with viruses that share several characteristics. They all have single-stranded multipartit...

journal_title：Viruses

authors： Mielke-Ehret N,Mühlbach HP

更新日期：2012-09-01 00:00:00

abstract：:Human herpesvirus-6A and B (HHV-6A, HHV-6B) have recently defined endogenous genomes, resulting from integration into the germline: chromosomally-integrated "CiHHV-6A/B". These affect approximately 1.0% of human populations, giving potential for virus gene expression in every cell. We previously showed that CiHHV-6A w...

journal_title：Viruses

authors： Tweedy J,Spyrou MA,Pearson M,Lassner D,Kuhl U,Gompels UA

更新日期：2016-01-15 00:00:00

abstract：:Prymnesium parvum is a toxin-producing haptophyte that causes harmful algal blooms globally, leading to large-scale fish kills that have severe ecological and economic implications. For the model haptophyte, Emiliania huxleyi, it has been shown that large dsDNA viruses play an important role in regulating blooms and t...

journal_title：Viruses

authors： Wagstaff BA,Vladu IC,Barclay JE,Schroeder DC,Malin G,Field RA

更新日期：2017-03-09 00:00:00

abstract：BACKGROUND:Duck plague virus (DPV) can induce apoptosis in duck embryo fibroblasts (DEFs) and in infected ducks, but the molecular mechanism of DPV-induced apoptosis remains unknown. METHODS:We first used qRT-PCR and a Caspase-Glo assay to determine whether the caspase protein family plays an important role in DPV-ind...

journal_title：Viruses

authors： Zhao C,Wang M,Cheng A,Yang Q,Wu Y,Jia R,Zhu D,Chen S,Liu M,Zhao X,Zhang S,Liu Y,Yu Y,Zhang L,Tian B,Rehman MU,Pan L,Chen X

更新日期：2019-02-24 00:00:00

abstract：:Like all other viruses, a successful egress of functional particles from infected cells is a prerequisite for foamy virus (FV) spread within the host. The budding process of FVs involves steps, which are shared by other retroviruses, such as interaction of the capsid protein with components of cellular vacuolar protei...

journal_title：Viruses

authors： Hütter S,Zurnic I,Lindemann D

更新日期：2013-04-10 00:00:00

abstract：:Porcine circovirus 3 (PCV3) has been identified as a putative swine pathogen with a subset of infections resulting in stillborn and mummified fetuses, encephalitis and myocarditis in perinatal, and periarteritis in growing pigs. Three PCV3 isolates were isolated from weak-born piglets or elevated stillborn and mummifi...

journal_title：Viruses

authors： Mora-Díaz J,Piñeyro P,Shen H,Schwartz K,Vannucci F,Li G,Arruda B,Giménez-Lirola L

更新日期：2020-02-16 00:00:00

abstract：:West Nile virus (WNV) is prevalent in Africa, Europe, the Middle East, West Asia, and North America, and causes epidemic encephalitis. To date, no effective therapy for WNV infection has been developed; therefore, there is urgent need to find an efficient method to prevent WNV disease. In this study, we prepared and e...

journal_title：Viruses

authors： Cui J,Zhao Y,Wang H,Qiu B,Cao Z,Li Q,Zhang Y,Yan F,Jin H,Wang T,Sun W,Feng N,Gao Y,Sun J,Wang Y,Perlman S,Zhao J,Yang S,Xia X

更新日期：2016-12-18 00:00:00

abstract：:One hundred Prunus trees, including almond (P. dulcis), apricot (P. armeniaca), nectarine (P. persica var. nucipersica), peach (P. persica), plum (P. domestica), purple leaf plum (P. cerasifera) and sweet cherry (P. avium), were selected from growing regions Australia-wide and tested for the presence of 34 viruses and...

journal_title：Viruses

authors： Kinoti WM,Nancarrow N,Dann A,Rodoni BC,Constable FE

更新日期：2020-02-23 00:00:00

abstract：:Efforts towards developing a vaccine for Middle East respiratory syndrome coronavirus (MERS-CoV) have yielded promising results. Utilizing a variety of platforms, several vaccine approaches have shown efficacy in animal models and begun to enter clinical trials. In this review, we summarize the current progress toward...

journal_title：Viruses

authors： Schindewolf C,Menachery VD

更新日期：2019-01-17 00:00:00

abstract：:Double-stranded DNA viruses package their genomes into pre-assembled protein procapsids. This process is driven by macromolecular motors that transiently assemble at a unique vertex of the procapsid and utilize homomeric ring ATPases to couple genome encapsidation to ATP hydrolysis. Here, we describe the biochemical a...

journal_title：Viruses

authors： Reyes-Aldrete E,Dill EA,Bussetta C,Szymanski MR,Diemer G,Maindola P,White MA,Bujalowski WM,Choi KH,Morais MC

更新日期：2020-12-23 00:00:00

abstract：:The subgroup A through E avian sarcoma and leukosis viruses (ASLV(A) through ASLV(E)) are a group of highly related alpharetroviruses that have evolved their envelope glycoproteins to use different receptors to enable efficient virus entry due to host resistance and/or to expand host range. Previously, we demonstrated...

journal_title：Viruses

authors： Munguia A,Federspiel MJ

更新日期：2019-06-05 00:00:00

abstract：:West Nile virus (WNV) is an important emerging neurotropic virus, responsible for increasingly severe encephalitis outbreaks in humans and horses worldwide. However, the mechanism by which the virus gains entry to the brain (neuroinvasion) remains poorly understood. Hypotheses of hematogenous and transneural entry hav...

journal_title：Viruses

authors： Suen WW,Prow NA,Hall RA,Bielefeldt-Ohmann H

更新日期：2014-07-18 00:00:00

abstract：:Environmental genomics can describe all forms of organisms--cellular and viral--present in a community. The analysis of such eco-systems biology data relies heavily on reference databases, e.g., taxonomy or gene function databases. Reference databases of symbiosis sensu lato, although essential for the analysis of org...

journal_title：Viruses

authors： Mihara T,Nishimura Y,Shimizu Y,Nishiyama H,Yoshikawa G,Uehara H,Hingamp P,Goto S,Ogata H

更新日期：2016-03-01 00:00:00

abstract：:Papaya ringspot virus (PRSV), a common potyvirus infecting papaya plants worldwide, can lead to either antagonism or synergism in mixed infections with Papaya mosaic virus (PapMV), a potexvirus. These two unrelated viruses produce antagonism or synergism depending on their order of infection in the plant. When PRSV is...

journal_title：Viruses

authors： Vargas-Mejía P,Vega-Arreguín J,Chávez-Calvillo G,Ibarra-Laclette E,Silva-Rosales L

更新日期：2020-02-19 00:00:00

abstract：:The Protoparvovirus (PtPV) genus of the Parvoviridae family of viruses includes important animal pathogens and reference molecular models for the entire family. Some virus members of the PtPV genus have arisen as promising tools to treat tumoral processes, as they exhibit marked oncotropism and oncolytic activities wh...

journal_title：Viruses

authors： Ros C,Bayat N,Wolfisberg R,Almendral JM

更新日期：2017-10-26 00:00:00

abstract：:Mutations are incorporated into the genomes of RNA viruses at an optimal frequency and altering this precise frequency has been proposed as a strategy to create live-attenuated vaccines. However, determining the effect of specific mutations that alter fidelity has been difficult because of the rapid selection of the v...

journal_title：Viruses

authors： Patterson EI,Khanipov K,Swetnam DM,Walsdorf S,Kautz TF,Thangamani S,Fofanov Y,Forrester NL

更新日期：2020-05-15 00:00:00