Abstract：
:Apart from optimal nutritional value, human milk is the feeding strategy to support the immature immunological system of developing newborns and infants. The most beneficial dietary carbohydrate components of breast milk are human milk oligosaccharides (HMOs) and glycoproteins (HMGs), involved in both specific and nonspecific immunity. Fucosylated oligosaccharides represent the largest fraction of human milk oligosaccharides, with the simplest and the most abundant being 2'-fucosyllactose (2'FL). Fucosylated oligosaccharides, as well as glycans of glycoproteins, as beneficial dietary sugars, elicit anti-adhesive properties against fucose-dependent pathogens, and on the other hand are crucial for growth and metabolism of beneficial bacteria, and in this aspect participate in shaping a healthy microbiome. Well-documented secretor status related differences in the fucosylation profile of HMOs and HMGs may play a key but underestimated role in assessment of susceptibility to fucose-dependent pathogen infections, with a potential impact on applied clinical procedures. Nevertheless, due to genetic factors, about 20% of mothers do not provide their infants with beneficial dietary carbohydrates such as 2'-FL and other α1,2-fucosylated oligosaccharides and glycans of glycoproteins, despite breastfeeding them. The lack of such structures may have important implications for a wide range of aspects of infant well-being and healthcare. In light of the above, some artificial mixtures used in infant nutrition are supplemented with 2'-FL to more closely approximate the unique composition of maternal milk, including dietary-derived fucosylated oligosaccharides and glycoproteins.
journal_name
Nutrientsjournal_title
Nutrientsauthors
Orczyk-Pawiłowicz M,Lis-Kuberka Jdoi
10.3390/nu12041105subject
Has Abstractpub_date
2020-04-16 00:00:00issue
4issn
2072-6643pii
nu12041105journal_volume
12pub_type
杂志文章,评审相关文献
Nutrients文献大全abstract：:Ultraviolet B (UVB) irradiation is viewed as the principal inducer of skin photo-aging, associated with acceleration of collagen degradation and upregulation of matrix metalloproteinases (MMPs). The ethnic groups of southern/western China use Fuzhuan brick-tea (FBT) as a beverage and as a nutritional supplement. In th...
journal_title：Nutrients
pub_type： 杂志文章
doi：10.3390/nu11010060
更新日期：2018-12-28 00:00:00
abstract：:The current performance indicator for universal salt iodisation (USI) is the percentage of households using adequately iodised salt. However, the proportion of dietary salt from household salt is decreasing with the increase in consumption of processed foods and condiments globally. This paper reports on case studies ...
journal_title：Nutrients
pub_type： 杂志文章
doi：10.3390/nu9080797
更新日期：2017-07-26 00:00:00
abstract：:Observational studies have shown that dietary fiber intake is associated with decreased risk of cardiovascular disease. Dietary fiber is a non-digestible form of carbohydrates, due to the lack of the digestive enzyme in humans required to digest fiber. Dietary fibers and lignin are intrinsic to plants and are classifi...
journal_title：Nutrients
pub_type： 杂志文章,评审
doi：10.3390/nu11051155
更新日期：2019-05-23 00:00:00
abstract：:Distarch phosphate is a resistant starch type 4 (RS4) containing phosphodiester cross-links within and between starch molecules. This study examined the glycemic effects of VERSAFIBE 1490™ resistant starch, a distarch phosphate derived from potato, containing 90% total dietary fiber (TDF, AOAC 991.43 method). In this ...
journal_title：Nutrients
pub_type： 杂志文章,随机对照试验
doi：10.3390/nu9030237
更新日期：2017-03-05 00:00:00
abstract：:The ketogenic diet (KD), a high-lipid and low-carbohydrate diet, has been used in the treatment of epilepsy, neurodegenerative disorders, inborn errors of metabolism and cancer; however, the exact mechanism/s of its therapeutic effect is not completely known. We hypothesized that sirtuins (SIRT)-a group of seven NAD-d...
journal_title：Nutrients
pub_type： 杂志文章
doi：10.3390/nu12082379
更新日期：2020-08-08 00:00:00
abstract：:Cancer is a multistage and multifactorial condition with genetic and environmental factors modulating tumorogenesis and disease progression. Nevertheless, cancer is preventable, as one third of cancer deaths could be avoided by modifying key risk factors. Nutrients can directly affect fundamental cellular processes an...
journal_title：Nutrients
pub_type： 杂志文章,评审
doi：10.3390/nu9101076
更新日期：2017-09-28 00:00:00
abstract：BACKGROUND:A clear evidence on the benefits of reducing salt in people with chronic kidney disease (CKD) is still lacking. Salt restriction in CKD may allow better control of blood pressure (BP) as shown in a previous systematic review while the effect on proteinuria reduction remains poorly investigated. METHODS:We p...
journal_title：Nutrients
pub_type： 杂志文章,meta分析,评审
doi：10.3390/nu10060732
更新日期：2018-06-06 00:00:00
abstract：:Low temperature long time (LTLT) sous-vide cooking may modify meat proteins in a way that could promote satiety. We investigated the effects of (1) cooking method (LTLT 58 °C vs. oven 160 °C), (2) LTLT holding time (17 h vs. 72 min), and (3) pork structure, LTLT 58 °C for 17 h (minced vs. roast) on appetite regulation...
journal_title：Nutrients
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.3390/nu9090941
更新日期：2017-08-26 00:00:00
abstract：:Nutrimiromics studies the influence of the diet on the modification of gene expression due to epigenetic processes related to microRNAs (miRNAs), which may affect the risk for the development of chronic diseases. miRNAs are a class of non-coding endogenous RNA molecules that are usually involved in post-transcriptiona...
journal_title：Nutrients
pub_type： 杂志文章,评审
doi：10.3390/nu9111168
更新日期：2017-10-27 00:00:00
abstract：:Modified NUTRIC (mNUTRIC) score is a useful assessment tool to determine the risk of malnutrition in patients on mechanical ventilation (MV). We identified associations between postoperative calorie adequacy, 30-day mortality, and surgical outcomes in patients with high mNUTRIC scores. Medical records of 272 patients ...
journal_title：Nutrients
pub_type： 杂志文章
doi：10.3390/nu10111589
更新日期：2018-10-29 00:00:00
abstract：:Reduction in cholesterol blood levels represents one of the therapeutic goals to achieve in order to reduce the occurrence of cardiovascular diseases. Commonly, this goal is attempted by promoting healthy lifestyle behaviors and low-fat diets. Recently, several nutraceuticals have been shown to possess cholesterol-low...
journal_title：Nutrients
pub_type： 杂志文章
doi：10.3390/nu11010163
更新日期：2019-01-14 00:00:00
abstract：:Fruits and vegetables are pivotal for a healthy diet due partly to their content in bioactive compounds. It is for this reason that we conducted a parallel study to unravel the possible effect on cardiometabolic parameters of the ingestion of anthocyanins, xanthophylls, or both groups of bioactives together in postmen...
journal_title：Nutrients
pub_type： 杂志文章,随机对照试验
doi：10.3390/nu11071533
更新日期：2019-07-05 00:00:00
abstract：:Hyperhomocysteinemia (HHcy) is recognized as a risk factor for cardiovascular disease. However, the prevalence of HHcy and its role in association with target organ damage in patients with chronickidney disease (CKD) are not well understood. This cross-sectional study included 1042 CKD patients who were admitted to ou...
journal_title：Nutrients
pub_type： 杂志文章
doi：10.3390/nu8100645
更新日期：2016-10-20 00:00:00
abstract：:The effect of the betaine: homocysteine methyltransferase BHMT c.716G>A (G: guanosine; A: adenosine) single nucleotide polymorphism (SNP) on the BHMT pathway is unknown during pregnancy. We hypothesised that it impairs betaine to dimethylglycine conversion and that folate status modifies its effect. We studied 612 wom...
journal_title：Nutrients
pub_type： 杂志文章
doi：10.3390/nu8100621
更新日期：2016-10-09 00:00:00
abstract：:Crocin, a major constituent of Gardenia jasminoides, is a natural colorant carotenoid compound that has been reported to have anti-inflammatory effects. This study investigated the therapeutic effects of crocin on mice with atopic dermatitis induced by Dermatophagoides farinae crude extract, which is a common environm...
journal_title：Nutrients
pub_type： 杂志文章
doi：10.3390/nu10111625
更新日期：2018-11-02 00:00:00
abstract：:Celiac disease (CD) is an autoimmune-mediated enteropathy triggered by dietary gluten in genetically prone individuals. The current treatment for CD is a strict lifelong gluten-free diet. However, in some CD patients following a strict gluten-free diet, the symptoms do not remit. These cases may be refractory CD or du...
journal_title：Nutrients
pub_type： 杂志文章,评审
doi：10.3390/nu5104174
更新日期：2013-10-21 00:00:00
abstract：:Emerging research demonstrates polyphenol-rich diets like the Mediterranean diet may play a role in improving the outcomes of adult cancer therapy. To date, there are no trials assessing the intake or efficacy of polyphenol-rich diets in childhood cancer patients. In this study we collected dietary data on 59 childhoo...
journal_title：Nutrients
pub_type： 杂志文章
doi：10.3390/nu11112835
更新日期：2019-11-19 00:00:00
abstract：:We investigated the effects of exogenous glucagon-like peptide-2 (GLP-2) on mucosal atrophy and intestinal antioxidant capacity in a mouse model of total parenteral nutrition (TPN). Male mice (6-8 weeks old) were divided into three groups (n = 8 for each group): a control group fed a standard laboratory chow diet, and...
journal_title：Nutrients
pub_type： 杂志文章
doi：10.3390/nu8010033
更新日期：2016-01-09 00:00:00
abstract：:A low Omega-3 Index (eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) in erythrocytes) is associated with cardiac, cerebral, and other health issues. Intake of EPA and DHA, but not of alpha-linolenic acid (ALA), increases the Omega-3 Index. We investigated bioavailability, safety, palatability and tolerabili...
journal_title：Nutrients
pub_type： 杂志文章,随机对照试验
doi：10.3390/nu9060629
更新日期：2017-06-19 00:00:00
abstract：:Folate, vitamin B6, and vitamin B12 intake can be important regulators for obesity development. Thus, we investigated the possible association between the intake of these vitamins and the excess body weight or obesity prevalence in the participants of the Cohort of Universities in Minas Gerais (CUME project). This stu...
journal_title：Nutrients
pub_type： 杂志文章
doi：10.3390/nu11030518
更新日期：2019-02-28 00:00:00
abstract：:Water is essential for the proper functioning of the body. Even though a recommendation exists for adequate water intake for Koreans, studies identifying actual water intake from all beverages and foods consumed daily in the Korean population are limited. Thus, we estimated total water intake from both beverages and f...
journal_title：Nutrients
pub_type： 杂志文章
doi：10.3390/nu8100617
更新日期：2016-10-04 00:00:00
abstract：:A pro-coagulative state is related to increased risk of cardiovascular diseases but also certain cancers. Since experimental and smaller human studies suggest that diet, physical activity, and body weight may all affect coagulation, we evaluated associations between these lifestyle factors and hemostatic biomarkers in...
journal_title：Nutrients
pub_type： 杂志文章
doi：10.3390/nu11092067
更新日期：2019-09-03 00:00:00
abstract：:Currently, the majority of neonates born to organ recipient mothers on chronic immunosuppressive therapy are formula fed. However, over the past few years, evidence has grown, suggesting that breastfeeding might be possible and beneficial. We designed a study assessing the transfer of tacrolimus into the colostrum of ...
journal_title：Nutrients
pub_type： 杂志文章
doi：10.3390/nu10030267
更新日期：2018-02-27 00:00:00
abstract：:Hedychium coronarium has a long history of use worldwide as a food and in folk medicine. In this study, we aimed to investigate the effect of an aqueous extract of H. coronarium leaves (HC) on type 2 diabetes mellitus (T2DM). Two types of animal models were used in this study: Streptozotocin (STZ)-induced T2DM (Wistar...
journal_title：Nutrients
pub_type： 杂志文章
doi：10.3390/nu11030629
更新日期：2019-03-14 00:00:00
abstract：:This study investigated effects of patchouli essential oil (PEO) inhalation on metabolic parameters. First, to characterize aromatic compounds in PEO, solid-phase microextraction-gas chromatography/mass spectrometric detection was employed in which 19 aromatic compounds were identified. In GC-olfactometry analysis, li...
journal_title：Nutrients
pub_type： 杂志文章
doi：10.3390/nu12072077
更新日期：2020-07-13 00:00:00
abstract：:Green gastric residuals (GR) are often considered as a sign of feed intolerance and discarded in preterm infants. Probiotics are known to enhance feed tolerance in preterm infants. To assess the composition (primary outcome) and volume of discarded green GRs, and feeding outcomes in extremely preterm (EP) infants in a...
journal_title：Nutrients
pub_type： 杂志文章
doi：10.3390/nu12092585
更新日期：2020-08-26 00:00:00
abstract：:Sandwiches are considered a staple in diets of United States adults. Previous research with Healthy Aging in Neighborhoods of Diversity across the Life Span study participants revealed that 16% consume a sandwich dietary pattern providing with 44% of their daily energy. Yet, little is known about the effect of sandwic...
journal_title：Nutrients
pub_type： 杂志文章
doi：10.3390/nu12092807
更新日期：2020-09-13 00:00:00
abstract：:Immigrants in the U.S. may encounter challenges of acculturation, including dietary habits, as they adapt to new surroundings. We examined Vietnamese and Hispanic immigrant children's American food consumption patterns in a convenience sample of 63 Vietnamese and Hispanic children in grades four to six who were attend...
journal_title：Nutrients
pub_type： 杂志文章
doi：10.3390/nu9050460
更新日期：2017-05-05 00:00:00
abstract：:Animal studies indicate Salacia reduces body weight, possibly due to its α-glucosidase inhibitor (α-GI) properties, but this has not been examined previously. In this study, a randomized, placebo-controlled, three-way cross-over design was used to evaluate whether Salacia Chinensis (SC) reduces appetite in healthy ove...
journal_title：Nutrients
pub_type： 杂志文章,随机对照试验
doi：10.3390/nu9080869
更新日期：2017-08-12 00:00:00
abstract：:Information on the etiology of anemia is necessary to design effective anemia control programs. Our objective was to measure the prevalence of inherited hemoglobin disorders (IHD) in a representative sample of children in urban Cameroon, and examine the relationships between IHD and anemia. In a cluster survey of chil...
journal_title：Nutrients
pub_type： 杂志文章
doi：10.3390/nu9070693
更新日期：2017-07-03 00:00:00
