Influence of government price regulation and deregulation on the price of antineoplastic medications in China: a controlled interrupted time series study.

abstract：INTRODUCTION:Overtreatment of localised prostate cancer is substantial despite increased use of active surveillance. No randomised trials help define how to monitor patients or when to initiate treatment with curative intent. METHODS AND ANALYSIS:A randomised, multicentre, intervention trial designed to evaluate the s...

journal_title：BMJ open

authors： Ahlberg MS,Adami HO,Beckmann K,Bertilsson H,Bratt O,Cahill D,Egevad L,Garmo H,Holmberg L,Johansson E,Rannikko A,Van Hemelrijck M,Jäderling F,Wassberg C,Åberg UWN,Bill-Axelson A

更新日期：2019-08-22 00:00:00

abstract：OBJECTIVE:To examine the impact of caesarean section on breastfeeding indicators-early initiation of breastfeeding, exclusive breastfeeding under 6 months and children ever breastfed (at least once)-in sub-Saharan Africa. DESIGN:Secondary analysis of Demographic and Health Surveys (DHS). SETTING:Thirty-three low-inco...

journal_title：BMJ open

authors： Yisma E,Mol BW,Lynch JW,Smithers LG

更新日期：2019-09-04 00:00:00

abstract：OBJECTIVE:Animal and in vitro studies suggest that viral acute respiratory infection (VARI) can predispose to pneumococcal infection. These findings suggest that the prevention of VARI can yield additional benefits for the control of pneumococcal disease (PD). In population-based studies, however, the evidence is not i...

journal_title：BMJ open

authors： Li Y,Peterson ME,Campbell H,Nair H

更新日期：2018-04-21 00:00:00

abstract：OBJECTIVE:To systematically review the literature for evidence of smoking and alcohol intake as independent risk factors for invasive pneumococcal disease (IPD). DESIGN:Systematic review. METHODS:MEDLINE (1946-May 2012) and EMBASE (1947-May 2012) were searched for studies investigating alcohol or smoking as risk fact...

journal_title：BMJ open

authors： Cruickshank HC,Jefferies JM,Clarke SC

更新日期：2014-06-20 00:00:00

abstract：OBJECTIVE:Leave-on emollients form the mainstay of eczema treatment, but adherence is poor. We aimed to explore parents'/carers' views on effectiveness and acceptability of leave-on emollients for childhood eczema through secondary analysis of data from 2 qualitative data sets. SETTING:Study 1 recruited through mail-o...

journal_title：BMJ open

authors： Santer M,Muller I,Yardley L,Lewis-Jones S,Ersser S,Little P

更新日期：2016-08-19 00:00:00

abstract：INTRODUCTION:HIV-associated neurocognitive disorder (HAND) may affect 30%-50% of people ageing with HIV. HAND may increase stress and anxiety, and impede coping. Psychosocial group therapy may ameliorate HAND's symptoms, yet the ideal intervention is unclear. This protocol outlines a pilot randomised controlled trial (...

journal_title：BMJ open

authors： Eaton AD,Walmsley SL,Craig SL,Rourke SB,Sota T,McCullagh JW,Fallon BA

更新日期：2019-10-31 00:00:00

abstract：OBJECTIVES:The objectives of this study were to describe the methods used to assess the quality of linkage between records of babies' birth registration and hospital birth records, and to evaluate the potential bias that may be introduced because of these methods. DESIGN/SETTING:Data from the civil registration and th...

journal_title：BMJ open

authors： Coathup V,Macfarlane A,Quigley M

更新日期：2020-10-26 00:00:00

abstract：OBJECTIVE:To describe the minimal disease activity (MDA) rate over time in patients with psoriatic arthritis (PsA) receiving antitumour necrosis factor agents, evaluate prognostic factors of MDA achievement and identify the most common unmet criteria among MDA achievers. DESIGN:Biologic Treatment Registry Across Canad...

journal_title：BMJ open

authors： Rahman P,Zummer M,Bessette L,Baer P,Haraoui B,Chow A,Kelsall J,Kapur S,Rampakakis E,Psaradellis E,Lehman AJ,Nantel F,Osborne B,Tkaczyk C

更新日期：2017-08-30 00:00:00

abstract：BACKGROUND:Delirium is common among seniors discharged from the emergency department (ED) and associated with increased risk of mortality. Prior research has addressed mortality associated with seniors discharged from the ED with delirium, however has generally relied on data from one or a small number of institutions ...

journal_title：BMJ open

authors： Israni J,Lesser A,Kent T,Ko K

更新日期：2018-05-05 00:00:00

abstract：BACKGROUND:The juvenile form of Huntington's disease (HD) is a rare disorder. There are no population-based estimates of either its incidence or prevalence in any population in the world. The present study was undertaken to estimate the frequency of juvenile HD in the UK and to examine the range of pharmacological trea...

journal_title：BMJ open

authors： Douglas I,Evans S,Rawlins MD,Smeeth L,Tabrizi SJ,Wexler NS

更新日期：2013-04-03 00:00:00

abstract：OBJECTIVE:To describe health-related quality of life (HRQOL) and psychological well-being of children and adolescents at enrolment in a multidisciplinary community-based obesity programme and to determine association with ethnicity. This programme targeted indigenous people and those from most deprived households. Furt...

journal_title：BMJ open

authors： Anderson YC,Wynter LE,Treves KF,Grant CC,Stewart JM,Cave TL,Wouldes TA,Derraik JGB,Cutfield WS,Hofman PL

更新日期：2017-08-09 00:00:00

abstract：OBJECTIVES:The aim of this study was to identify which behaviour change techniques (BCTs) were present in intervention and control groups of randomised controlled trials (RCTs) included in a Cochrane systematic review. SETTING:The RCTs included were conducted in community, primary and/or ambulatory-care settings. PAR...

journal_title：BMJ open

authors： Scott C,de Barra M,Johnston M,de Bruin M,Scott N,Matheson C,Bond C,Watson MC

更新日期：2020-09-15 00:00:00

abstract：OBJECTIVES:In the USA, there is little systematic evidence about the real-world trajectories of patient medical care after hospice enrolment. The objective of this study was to analyse predictors of the length of stay for hospice patients who were admitted to hospital in a retrospective analysis of the mandatorily repo...

journal_title：BMJ open

authors： Pathak EB,Wieten S,Djulbegovic B

更新日期：2014-07-22 00:00:00

abstract：INTRODUCTION:Reduced hip abductor strength may indirectly lead to changes in knee kinematics and functional impairment and has been reported in patients with patellofemoral pain and knee osteoarthritis (OA). Limited information is available regarding hip abductor strength following total or unicompartmental knee arthro...

journal_title：BMJ open

authors： Kvarda P,Nüesch C,Egloff C,Appenzeller-Herzog C,Mündermann A,Ismailidis P

更新日期：2020-08-13 00:00:00

abstract：INTRODUCTION:Dizziness is a common symptom in general practice with a high prevalence among older adults. The most common cause of dizziness in general practice is peripheral vestibular disease. Vestibular rehabilitation (VR) is a safe and effective treatment for peripheral vestibular disease that entails specific exer...

journal_title：BMJ open

authors： van Vugt VA,van der Wouden JC,Bosmans JE,Smalbrugge M,van Diest W,Essery R,Yardley L,van der Horst HE,Maarsingh OR

更新日期：2017-01-20 00:00:00

abstract：OBJECTIVES:To describe the effect of in utero exposure to the buprenorphine+naloxone combination product in a rural and remote population. SETTING:A district hospital that services rural and remote, fly-in communities in Northwestern Ontario, Canada. PARTICIPANTS:A retrospective cohort study was conducted of 855 moth...

journal_title：BMJ open

authors： Jumah NA,Edwards C,Balfour-Boehm J,Loewen K,Dooley J,Gerber Finn L,Kelly L

更新日期：2016-10-31 00:00:00

abstract：INTRODUCTION:Severe and persistent mental illness (SPMI) can significantly impact a person's social, personal and professional life. Previous studies have demonstrated pharmacists' roles in mental healthcare; however, limited studies to date have focused on pharmacists' roles in providing healthcare services, specifica...

journal_title：BMJ open

authors： El-Den S,McMillan SS,Wheeler AJ,Ng R,Roennfeldt H,O'Reilly CL

更新日期：2020-07-13 00:00:00

abstract：INTRODUCTION:Fructosamine is a marker of glucose control reflecting the average glycaemic level over the preceding 2-3 weeks. Fructosamine has not gained as much popularity as glycated haemoglobin (HbA1c) for diabetes mellitus (DM) control monitoring, and the related underlying reasons remain unclear. We aim to search ...

journal_title：BMJ open

authors： Nansseu JR,Fokom-Domgue J,Noubiap JJ,Balti EV,Sobngwi E,Kengne AP

更新日期：2015-05-15 00:00:00

abstract：BACKGROUND:There is a growing body of evidence associating financial strain (FS) with poor health but most of this research has been cross-sectional and adult-focused. During the 'Great Recession' many UK households experienced increased FS. The primary aim of this study was to determine the impact of increased FS on c...

journal_title：BMJ open

authors： McKenna C,Law C,Pearce A

更新日期：2017-03-09 00:00:00

abstract：OBJECTIVES:To investigate factors associated with movement behaviours among White British (WB) and South Asian (SA) children aged 6-8 years during school terms and holidays. DESIGN:Cross-sectional. SETTING:Three primary schools from the Bradford area, UK. PARTICIPANTS:One hundred and sixty WB and SA children aged 6-...

journal_title：BMJ open

authors： Nagy LC,Faisal M,Horne M,Collings P,Barber S,Mohammed M

更新日期：2019-08-18 00:00:00

abstract：OBJECTIVES:To explore whether knowledge about the harms of ultraviolet radiation (UVR) influences UK university students' sun-related behaviours and examine in depth their attitudes towards: sun protection, natural and artificial tanning behaviours. DESIGN:Qualitative methodology with 15 semistructured, individual int...

journal_title：BMJ open

authors： Kirk L,Greenfield S

更新日期：2017-03-13 00:00:00

abstract：OBJECTIVES:To analyse the trends and trend changes in myocardial infraction (MI) and coronary heart disease (CHD) admissions, to investigate the effects of the 2007 smoke-free legislation on these trends, and to consider the policy implications of any findings. DESIGN SETTING:Liverpool (city), UK. PARTICIPANTS:Hospit...

journal_title：BMJ open

authors： Liu A,Guzman Castillo M,Capewell S,Lucy J,O'Flaherty M

更新日期：2013-11-25 00:00:00

abstract：INTRODUCTION:Clinical guidelines recommend that patients with type 1 diabetes (T1D) learn carbohydrate counting or similar methods to improve glycaemic control. Although systematic educating in carbohydrate counting is still not offered as standard-of-care for all patients on multiple daily injections (MDI) insulin the...

journal_title：BMJ open

authors： Ewers B,Vilsbøll T,Andersen HU,Bruun JM

更新日期：2019-09-03 00:00:00

abstract：OBJECTIVES:To identify the diagnostic accuracy of common imaging modalities, chest X-ray (CXR) and CT, for diagnosis of COVID-19 in the general emergency population in the UK and to find the association between imaging features and outcomes in these patients. DESIGN:Retrospective analysis of electronic patient records...

journal_title：BMJ open

authors： Borakati A,Perera A,Johnson J,Sood T

更新日期：2020-11-06 00:00:00

abstract：OBJECTIVE:Since most biomedical research focuses on a specific disease, evaluation of research output requires disease-specific bibliometric indicators. Currently used methods are insufficient. The aim of this study is to develop a method that enables detailed analysis of worldwide biomedical research output by disease...

journal_title：BMJ open

authors： van de Laar L,de Kruif T,Waltman L,Meijer I,Gupta A,Hagenaars N

更新日期：2018-06-04 00:00:00

abstract：CONTEXT:The Food and Drug Administration Modernization Act of 1997 (FDAMA) and the FDA Amendment Act of 2007 (FDAAA), respectively, established mandates for registration of interventional human research studies on the website clinicaltrials.gov (CTG) and for posting of results of completed studies. OBJECTIVE:To charac...

journal_title：BMJ open

authors： Gill CJ

更新日期：2012-08-29 00:00:00

abstract：OBJECTIVES:To examine the association between multisite musculoskeletal pain in adolescence and mental health disorders in young adulthood. DESIGN AND SETTING:Data were obtained from a linkage between the Norwegian Patient Registry (2008-2012) and the Norwegian Arctic Adolescent Health Study, a school-based survey con...

journal_title：BMJ open

authors： Eckhoff C,Straume B,Kvernmo S

更新日期：2017-02-10 00:00:00

abstract：OBJECTIVES:Domestic violence (DV) is hazardous to survivors' health, from injuries sustained and from resultant chronic physical and mental health problems. Support from friends and relatives is significant in the lives of DV survivors; research shows associations between positive support and the health, well-being and...

journal_title：BMJ open

authors： Gregory A,Feder G,Taket A,Williamson E

更新日期：2017-03-24 00:00:00

abstract：OBJECTIVE:To explore risks of experiencing intimate partner violence (IPV) after HIV infection among women with HIV in a postnatal care setting in Swaziland. DESIGN:A qualitative semistructured in-depth interview study, using thematic analysis with deductive and inductive coding, of IPV experiences after HIV infection...

journal_title：BMJ open

authors： Mulrenan C,Colombini M,Howard N,Kikuvi J,Mayhew SH,Integra Initiative.

更新日期：2015-05-14 00:00:00

abstract：OBJECTIVES:To compare the short-term and long-term effectiveness of human papillomavirus (HPV) tests in Norwegian Cervical Cancer Screening Programme (NCCSP). DESIGN:Nationwide register-based prospective follow-up study. SETTING:In 2005, the NCCSP implemented HPV testing in follow-up of unsatisfactory, atypical squam...

journal_title：BMJ open

authors： Nygård M,Røysland K,Campbell S,Dillner J

更新日期：2014-01-08 00:00:00