Juvenile Huntington's disease: a population-based study using the General Practice Research Database.

abstract：PURPOSE:Occupational and environmental exposures remain important modifiable risk factors of public health. Existing cohort studies are often limited by the level of detail of data collected on these factors and health. It is also often assumed that the more healthy group is over-represented in cohort studies, which is...

journal_title：BMJ open

authors： Slottje P,Yzermans CJ,Korevaar JC,Hooiveld M,Vermeulen RC

更新日期：2014-11-26 00:00:00

abstract：OBJECTIVE:To identify factors associated with health literacy in multimorbid patients. DESIGN:A nationwide cross-sectional study in Switzerland. Univariate and multivariate linear regressions were calculated to identify variables associated with health literacy. A multiple imputation approach was used to deal with mis...

journal_title：BMJ open

authors： N'Goran AA,Pasquier J,Deruaz-Luyet A,Burnand B,Haller DM,Neuner-Jehle S,Zeller A,Streit S,Herzig L,Bodenmann P

更新日期：2018-02-13 00:00:00

abstract：OBJECTIVES:The aim of the study was to assess whether gastrostomy placement before 18 months of age results in a greater increase in z-score for weight and to assess whether admission rates were reduced postgastrostomy in this age group. DESIGN:Retrospective cross-sectional study. SETTING:Single-centre secondary care...

journal_title：BMJ open

authors： Sharma R,Williams AN,Zaw W

更新日期：2012-11-21 00:00:00

abstract：OBJECTIVES:We piloted an intervention to determine if support from a case manager would assist adults being investigated for tuberculosis (TB) to link into TB and HIV care. DESIGN:Pilot interventional cohort study. PARTICIPANTS AND SETTING:Patients identified by primary healthcare clinic staff in South Africa as need...

journal_title：BMJ open

authors： Maraba N,Chihota V,McCarthy K,Churchyard GJ,Grant AD

更新日期：2018-05-24 00:00:00

abstract：OBJECTIVE:To compare cancer-related systematic reviews (SRs) published in the Cochrane Database of SRs (CDSR) and high-impact journals, with respect to type, content, quality and citation rates. DESIGN:Methodological SR with assessment and comparison of SRs and meta-analyses. Two authors independently assessed methodo...

journal_title：BMJ open

authors： Goldkuhle M,Narayan VM,Weigl A,Dahm P,Skoetz N

更新日期：2018-03-25 00:00:00

abstract：:Objective To investigate the views and practices of UK medical schools regarding the inclusion (or exclusion) of complementary and alternative medicine (CAM) in undergraduate medical curricula. Design Survey (by email) of UK medical schools offering MBBS (or equivalent) degrees. Results The overall response rate was...

journal_title：BMJ open

authors： Smith KR

更新日期：2011-06-08 00:00:00

abstract：OBJECTIVES:Child dental caries is a global public health challenge with high prevalence and wide inequalities. A complex public health programme (Childsmile) was established. We aimed to evaluate the reach of the programme and its impact on child oral health. SETTING:Education, health and community settings, Scotland-...

journal_title：BMJ open

authors： Kidd JB,McMahon AD,Sherriff A,Gnich W,Mahmoud A,Macpherson LM,Conway DI

更新日期：2020-11-24 00:00:00

abstract：OBJECTIVE:New electronic devices offer an opportunity within routine primary care settings for improving the detection of atrial fibrillation (AF), which is a common cardiac arrhythmia and a modifiable risk factor for stroke. We aimed to assess the performance of a modified blood pressure (BP) monitor and two single-le...

journal_title：BMJ open

authors： Kearley K,Selwood M,Van den Bruel A,Thompson M,Mant D,Hobbs FR,Fitzmaurice D,Heneghan C

更新日期：2014-05-02 00:00:00

abstract：OBJECTIVES:To investigate the prognostic value of the neurocognitive status measured by screening instruments, the Montreal Cognitive Assessment (MoCA) and Mini-Mental State Examination (MMSE), individually and in combination with the stroke severity scale, the National Institute of Health Stroke Scale (NIHSS), obtaine...

journal_title：BMJ open

authors： Dong Y,Slavin MJ,Chan BP,Venketasubramanian N,Sharma VK,Crawford JD,Collinson SL,Sachdev P,Chen CL

更新日期：2013-09-03 00:00:00

abstract：OBJECTIVES:In recent years, the involvement of pharmacy technicians in medication reconciliation has increasingly been investigated. The aim of this study was to assess the implications on professional roles and collaboration when a best possible medication history (BPMH) at admission is obtained by pharmacy technician...

journal_title：BMJ open

authors： Niederhauser A,Zimmermann C,Fishman L,Schwappach DLB

更新日期：2018-05-17 00:00:00

abstract：INTRODUCTION:Current pharmacological treatment options for hyperemesis gravidarum have been introduced based on scarce evidence and are often not sufficiently effective. Several case reports suggest that mirtazapine, an antidepressant, may be an effective treatment for hyperemesis gravidarum, but so far there are no co...

journal_title：BMJ open

authors： Ostenfeld A,Petersen TS,Futtrup TB,Andersen JT,Jensen AK,Westergaard HB,Pedersen LH,Løkkegaard ECL

更新日期：2020-03-24 00:00:00

abstract：OBJECTIVES:While increasing attention is paid to the rising prevalence of chronic diseases in Africa, there is little focus on chronic kidney disease (CKD). This systematic review assesses CKD burden among the general population and high-risk groups on the entire African continent. DESIGN, SETTING AND PARTICIPANTS:We ...

journal_title：BMJ open

authors： Abd ElHafeez S,Bolignano D,D'Arrigo G,Dounousi E,Tripepi G,Zoccali C

更新日期：2018-01-10 00:00:00

abstract：INTRODUCTION:Treatment fidelity is an important and often neglected component of complex behaviour change research. It is central to understanding treatment effects, especially for evaluations conducted outside of highly controlled research settings. Ensuring that promising interventions can be delivered adequately (ie...

journal_title：BMJ open

authors： Beck AK,Forbes E,Baker AL,Britton B,Oldmeadow C,Carter G

更新日期：2019-07-30 00:00:00

abstract：OBJECTIVE:The primary objective was to explore differences in perceived need for care (PNC), mental health services use (MHSU) and perceived sufficiency of care (PSC) between Canadian Armed Forces Regular Force (RegF) and Reserve Force (ResF) personnel with an objective need for mental health services. DESIGN:Data cam...

journal_title：BMJ open

authors： Boulos D,Fikretoglu D

更新日期：2019-09-18 00:00:00

abstract：OBJECTIVES:To gather knowledge on the current debate, opinions and attitudes of Italian patient and citizen groups on individual participant data (IPD) sharing from clinical studies. DESIGN:Cross-sectional online survey. SETTING AND PARTICIPANTS:A 22-item online questionnaire was sent by email to 2003 contacts of pat...

journal_title：BMJ open

authors： Colombo C,Roberto A,Krleza-Jeric K,Parmelli E,Banzi R

更新日期：2019-02-19 00:00:00

abstract：INTRODUCTION:Glaucoma is the second leading cause of age-related vision loss worldwide; it is an umbrella term that is used to describe a set of complex ocular disorders with a multifactorial aetiology. Both genetic and lifestyle risk factors for glaucoma are well established. Thus far, however, systematic reviews on t...

journal_title：BMJ open

authors： Asefa NG,Neustaeter A,Jansonius NM,Snieder H

更新日期：2018-02-28 00:00:00

abstract：OBJECTIVE:To investigate medications associated with cognitive function. DESIGN:Population-based cross-sectional cohort study. SETTING:UK Biobank. PARTICIPANTS:UK Biobank participants aged 37-73 years who completed cognitive tests at the baseline visit in 2006-2010. MAIN OUTCOME MEASURES:Cognitive test outcomes on ...

journal_title：BMJ open

authors： Nevado-Holgado AJ,Kim CH,Winchester L,Gallacher J,Lovestone S

更新日期：2016-11-30 00:00:00

abstract：PURPOSE:Chagas disease (CD) has become a global health issue mainly due to migration. Germany lacks surveillance data and is home to a large Latin American immigrant population. Recognising that Bolivia is the country with the highest CD prevalence in Latin America, this cross-sectional, descriptive pilot study investi...

journal_title：BMJ open

authors： Navarro M,Berens-Riha N,Hohnerlein S,Seiringer P,von Saldern C,Garcia S,Blasco-Hernández T,Navaza B,Shock J,Bretzel G,Hoelscher M,Löscher T,Albajar-Viñas P,Pritsch M

更新日期：2017-01-16 00:00:00

abstract：INTRODUCTION:Atrial fibrillation (AF) is the most common form of cardiac arrhythmia and is associated with a number of comorbidities such as coronary artery disease and heart failure. While physical activity is already implemented in current international guidelines for the prevention and treatment of AF, the precise r...

journal_title：BMJ open

authors： Zacher J,Dillschnitter K,Freitag N,Kreutz T,Bjarnason-Wehrens B,Bloch W,Predel HG,Schumann M

更新日期：2020-10-31 00:00:00

abstract：OBJECTIVES:To estimate the prevalence of and associations between anxiety, depression, post-traumatic stress disorder (PTSD), low subjective well-being (SWB), potential traumas and postmigration stress among refugees from Syria resettled in Sweden. DESIGN:A cross-sectional and population-based questionnaire study base...

journal_title：BMJ open

authors： Tinghög P,Malm A,Arwidson C,Sigvardsdotter E,Lundin A,Saboonchi F

更新日期：2017-12-29 00:00:00

abstract：OBJECTIVES:This study compared the impact of two different 8-week mindfulness based courses (.b Foundations and Mindfulness-Based Stress Reduction (MBSR)), delivered to school teachers, on quantitative (stress, anxiety and depression) and qualitative (experience, acceptability and implementation) outcomes. DESIGN:A mi...

journal_title：BMJ open

authors： Todd C,Cooksey R,Davies H,McRobbie C,Brophy S

更新日期：2019-07-04 00:00:00

abstract：BACKGROUND:The Baby Friendly Hospital Initiative (BFHI) is a practice guideline for healthcare providers to promote breastfeeding and increase breastfeeding rates. OBJECTIVE:This study aimed to examine reported experiences and views on breastfeeding of women using prenatal and postnatal services, and opinions of staff...

journal_title：BMJ open

authors： Mosher C,Sarkar A,Hashem AA,Hamadah RE,Alhoulan A,AlMakadma YA,Khan TA,Al-Hamdani AK,Senok A

更新日期：2016-12-16 00:00:00

abstract：INTRODUCTION:Premature infants are particularly vulnerable to brain injuries with associated cognitive and behavioural deficits. The worldwide first randomised interventional multicentre trial investigating the neuroprotective effects of erythropoietin (entitled 'Does erythropoietin improve outcome in very preterm infa...

journal_title：BMJ open

authors： Wehrle FM,Held U,O'Gorman RT,Disselhoff V,Schnider B,Fauchère JC,Hüppi P,Latal B,Hagmann CF

更新日期：2018-04-24 00:00:00

abstract：OBJECTIVES:This study sought to explore patients' experiences of living with, and adapting to, chronic obstructive pulmonary disease (COPD) in the rural context. Specifically, our research question was 'What are the barriers and facilitators to living with and adapting to COPD in rural Australia?' DESIGN:Qualitative, ...

journal_title：BMJ open

authors： Glenister K,Haines H,Disler R

更新日期：2019-10-07 00:00:00

abstract：OBJECTIVES:Identification of patients at increased mortality risk is important in the context of increasing multimorbidity and an ageing population, to help facilitate the planning and delivery of services. The aim of this study was to examine 1-year all-cause mortality in a cohort of primary care patients in whom infl...

journal_title：BMJ open

authors： Watson J,Whiting P,Salisbury C,Banks J,Hamilton W

更新日期：2020-10-15 00:00:00

abstract：INTRODUCTION:The use of social networks has been increasing worldwide. Mobile websites and applications (apps) allow people to network more quickly and have more partners for sex. This can facilitate risky sexual behaviours, such as having multiple partners and unprotected sex, which can lead to a higher incidence of s...

journal_title：BMJ open

authors： Queiroz JF,Medeiros KS,Sarmento ACA,Monteiro MN,Cobucci RN,Stransky B,Gonçalves AK

更新日期：2020-11-19 00:00:00

abstract：OBJECTIVE:Classifications of posture deviations are only possible compared with standard values. However, standard values have been published for healthy male adults but not for female adults. DESIGN:Observational study. SETTING:Institute of Occupational Medicine, Social Medicine and Environmental Medicine, Goethe-Un...

journal_title：BMJ open

authors： Ohlendorf D,Fisch V,Doerry C,Schamberger S,Oremek G,Ackermann H,Schulze J

更新日期：2018-08-05 00:00:00

abstract：INTRODUCTION:Dual antiplatelet therapy (DAPT) is routinely given to patients after percutaneous coronary intervention (PCI) with stenting; however, there is ongoing debate about the optimal duration, especially in specific patient groups. In the proposed systematic review, we intend to assess the optimal duration of DA...

journal_title：BMJ open

authors： Elliott J,Kelly SE,Bai Z,Skidmore B,Boucher M,So DYF,Wells GA

更新日期：2019-06-16 00:00:00

abstract：OBJECTIVES:To assess the association between blood circulating vitamin D levels and colorectal cancer risk in the Asian population. DESIGN:This is a systematic review and dose-response meta-analysis of observational studies that investigated the relationship between blood circulating vitamin D levels and colorectal ca...

journal_title：BMJ open

authors： Zhang L,Zou H,Zhao Y,Hu C,Atanda A,Qin X,Jia P,Jiang Y,Qi Z

更新日期：2019-12-23 00:00:00

abstract：OBJECTIVES:To update the estimation of the adult HIV prevalence and number of people living with HIV (PLHIV) in India for the year 2008-2009 with the combination of improved data and methods. DESIGN:Based on HIV sentinel surveillance (HSS) data and a set of epidemiological assumptions, estimates of HIV prevalence and ...

journal_title：BMJ open

authors： Pandey A,Sahu D,Bakkali T,Reddy D,Venkatesh S,Kant S,Bhattacharya M,Raj Y,Haldar P,Bhardwaj D,Chandra N

更新日期：2012-09-30 00:00:00