Heritability of glaucoma and glaucoma-related endophenotypes: systematic review and meta-analysis protocol.

abstract：OBJECTIVE:High-performance marine craft personnel (HPMCP) are regularly exposed to vibration and repeated shock (VRS) levels exceeding maximum limitations stated by international legislation. Whereas such exposure reportedly is detrimental to health and performance, the epidemiological data necessary to link these adve...

journal_title：BMJ open

authors： Lo Martire R,de Alwis MP,Äng BO,Garme K

更新日期：2017-07-20 00:00:00

abstract：OBJECTIVE:To determine whether kidney transplants performed during a weekend had worse outcomes than those performed during weekdays. DESIGN:Retrospective national database study. SETTING:United Network for Organ Sharing database of the USA. PARTICIPANTS:136,715 adult recipients of deceased donor single organ kidney...

journal_title：BMJ open

authors： Baid-Agrawal S,Martus P,Feldman H,Kramer H

更新日期：2016-04-07 00:00:00

abstract：OBJECTIVES:To examine the characteristics and persistence in patients newly initiated with oral anticoagulants (OACs) for stroke prevention in non-valvular atrial fibrillation (NVAF). DESIGN:Cohort study in Clinical Practice Research Datalink. SETTING:UK primary care. PARTICIPANTS:15 242 patients with NVAF newly pre...

journal_title：BMJ open

authors： Johnson ME,Lefèvre C,Collings SL,Evans D,Kloss S,Ridha E,Maguire A

更新日期：2016-09-26 00:00:00

abstract：INTRODUCTION:Patients presenting with acute intracerebral haemorrhage are at a high risk of exhibiting haematoma expansion, a phenomenon that can significantly worsen long-term functioning. Numerous clinical and radiological factors are associated with expansion. In a bid to better select patients at increased risk of ...

journal_title：BMJ open

authors： Yogendrakumar V,Moores M,Sikora L,Ramsay T,Fergusson DA,Dowlatshahi D

更新日期：2019-01-21 00:00:00

abstract：OBJECTIVES:To explore whether knowledge about the harms of ultraviolet radiation (UVR) influences UK university students' sun-related behaviours and examine in depth their attitudes towards: sun protection, natural and artificial tanning behaviours. DESIGN:Qualitative methodology with 15 semistructured, individual int...

journal_title：BMJ open

authors： Kirk L,Greenfield S

更新日期：2017-03-13 00:00:00

abstract：OBJECTIVES:To explore healthcare professionals (HCPs) experiences and challenges in diagnosing suspected lower limb cellulitis. SETTING:UK nationwide. PARTICIPANTS:20 qualified HCPs, who had a minimum of 2 years clinical experience as an HCP in the national health service and had managed a clinical case of suspected ...

journal_title：BMJ open

authors： Patel M,Lee SI,Levell NJ,Smart P,Kai J,Thomas KS,Leighton P

更新日期：2020-10-14 00:00:00

abstract：INTRODUCTION:While tobacco smoking prevalence is falling in many western societies, it remains elevated among high-priority cohorts. Rates up to 95% have been reported in women whose pregnancy is complicated by other substance use. In this group, the potential for poor pregnancy outcomes and adverse physical and neurob...

journal_title：BMJ open

authors： Jackson MA,Brown AL,Baker AL,Gould GS,Dunlop AJ

更新日期：2019-11-21 00:00:00

abstract：OBJECTIVES:Studies on ethnic disparities in glycaemic control have been contradictory, and compromised by excessively broad categories of ethnicity and inadequate adjustment for socioeconomic differences. We aimed to study the effect of ethnicity on glycaemic control in a large cohort of patients with type 2 diabetes. ...

journal_title：BMJ open

authors： Rawshani A,Svensson AM,Rosengren A,Zethelius B,Eliasson B,Gudbjörnsdottir S

更新日期：2015-06-05 00:00:00

abstract：OBJECTIVES:Atrial fibrillation (AF) is the most common cardiac rhythm disorder with a significant health burden. The aim of this study was to characterise patients with recently diagnosed AF and to estimate the rates of comorbidities and outcome events requiring hospitalisation in routine clinical practice. DESIGN:Pha...

journal_title：BMJ open

authors： Gallagher AM,van Staa TP,Murray-Thomas T,Schoof N,Clemens A,Ackermann D,Bartels DB

更新日期：2014-01-27 00:00:00

abstract：OBJECTIVES:To compare the clinical, socioeconomic and demographic characteristics of individuals diagnosed with Neisseria gonorrhoeae (NG) in the community using a concomitant nucleic acid amplification test (NAAT, AptimaCombo2) as part of the (community-based) UK Chlamydia Screening Programme (CSP), with those diagnos...

journal_title：BMJ open

authors： Cook PA,Evans-Jones J,Mallinson H,Wood M,Alloba F,Jones K,Strodtbeck S,Hanna-Bashara L

更新日期：2014-03-14 00:00:00

abstract：:Objective To investigate the views and practices of UK medical schools regarding the inclusion (or exclusion) of complementary and alternative medicine (CAM) in undergraduate medical curricula. Design Survey (by email) of UK medical schools offering MBBS (or equivalent) degrees. Results The overall response rate was...

journal_title：BMJ open

authors： Smith KR

更新日期：2011-06-08 00:00:00

abstract：OBJECTIVES:To assess the current evidence on the effect pre-arrest comorbidity has on survival and neurological outcomes following out-of-hospital cardiac arrest (OHCA). DESIGN:Systematic review according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses. DATA SOURCES:MEDLINE, Ovid Embase, Sco...

journal_title：BMJ open

authors： Majewski D,Ball S,Finn J

更新日期：2019-11-18 00:00:00

abstract：OBJECTIVES AND DESIGN:This field experiment aimed to compare bowel cancer screening participation rates prior to, during and after a mass media campaign promoting screening, and the extent to which a higher intensity campaign in one state led to higher screening rates compared with another state that received lower int...

journal_title：BMJ open

authors： Durkin SJ,Broun K,Spittal MJ,Wakefield MA

更新日期：2019-01-25 00:00:00

abstract：OBJECTIVE:The purpose of this study was to analyse the rate of knee arthroplasty in the population of patients with a history of arthroscopic chondroplasty of the knee, in England, over 10 years, with comparison to general population data for patients without a history of chondroplasty. DESIGN:Retrospective cohort stu...

journal_title：BMJ open

authors： Abram SGF,Palmer AJR,Judge A,Beard DJ,Price AJ

更新日期：2020-04-16 00:00:00

abstract：OBJECTIVES:To assess medical care and costs of the 3 highest prevalence lumbar disorders-non-specific low back pain (nLBP), intervertebral disc disorder (IDD) and spinal stenosis (SS)-from national billing data to provide basic information for standards of appropriate management. DESIGN:Retrospective analysis of Natio...

journal_title：BMJ open

authors： Ahn YJ,Shin JS,Lee J,Lee YJ,Kim MR,Park KB,Lee JH,Shin KM,Ha IH

更新日期：2016-09-12 00:00:00

abstract：OBJECTIVE:The Chief Nurse National Health Service Wales initiated a national survey of acute and community hospital patients in Wales to identify the prevalence of pressure ulcers and incontinence-associated dermatitis. METHODS:Teams of two nurses working independently assessed the skin of each inpatient who consented...

journal_title：BMJ open

authors： Clark M,Semple MJ,Ivins N,Mahoney K,Harding K

更新日期：2017-08-21 00:00:00

abstract：OBJECTIVES:For characterisation of mineral bone disease in chronic kidney disease (CKD), laboratory surrogates have been suggested. This observational should investigate the association of total and skeletal alkaline phosphatase (AP) with mortality of patients undergoing maintenance renal replacement therapy. SETTING:...

journal_title：BMJ open

authors： Beige J,Wendt R,Girndt M,Queck KH,Fiedler R,Jehle P

更新日期：2014-02-27 00:00:00

abstract：OBJECTIVE:To develop and validate a prediction model for identifying women at increased risk of developing gestational hypertension (GH) in Ghana. DESIGN:A prospective study. We used frequencies for descriptive analysis, χ2 test for associations and logistic regression to derive the prediction model. Discrimination wa...

journal_title：BMJ open

authors： Antwi E,Groenwold RH,Browne JL,Franx A,Agyepong IA,Koram KA,Klipstein-Grobusch K,Grobbee DE

更新日期：2017-01-16 00:00:00

abstract：INTRODUCTION:Dementia and Imagination is a multidisciplinary research collaboration bringing together arts and science to address current evidence limitations around the benefits of visual art activities in dementia care. The research questions ask: Can art improve quality of life and well-being? If it does make a diff...

journal_title：BMJ open

authors： Windle G,Newman A,Burholt V,Woods B,O'Brien D,Baber M,Hounsome B,Parkinson C,Tischler V

更新日期：2016-11-02 00:00:00

abstract：INTRODUCTION:Development of digital breast tomosynthesis (DBT) provides a technology that generates three-dimensional data sets, thus reducing the pitfalls of overlapping breast tissue. Observational studies suggest that the combination of two-dimensional (2D) digital mammography and DBT increases diagnostic accuracy. ...

journal_title：BMJ open

authors： Weigel S,Gerss J,Hense HW,Krischke M,Sommer A,Czwoydzinski J,Lenzen H,Kerschke L,Spieker K,Dickmaenken S,Baier S,Urban M,Hecht G,Heidinger O,Kieschke J,Heindel W

更新日期：2018-05-14 00:00:00

abstract：OBJECTIVES:To examine the effect of the new legislation on partial sickness benefit on subsequent work participation of Finns with long-term sickness absence. Additionally, we investigated whether the effect differed by sex, age or diagnostic category. DESIGN:A register-based quasi-experimental study compared the inte...

journal_title：BMJ open

authors： Kausto J,Viikari-Juntura E,Virta LJ,Gould R,Koskinen A,Solovieva S

更新日期：2014-12-24 00:00:00

abstract：INTRODUCTION:Although many effective treatment options exist, depression is still undertreated indicating gaps in the healthcare system. The complementary provision of mental healthcare through technologies (eg, computer, smartphone) has the potential to fill treatment gaps and to overcome access barriers to mental hea...

journal_title：BMJ open

authors： Köhnen M,Kriston L,Härter M,Dirmaier J,Liebherz S

更新日期：2019-03-27 00:00:00

abstract：OBJECTIVES:To assess which osmolarity equation best predicts directly measured serum/plasma osmolality and whether its use could add value to routine blood test results through screening for dehydration in older people. DESIGN:Diagnostic accuracy study. PARTICIPANTS:Older people (≥65 years) in 5 cohorts: Dietary Stra...

journal_title：BMJ open

authors： Hooper L,Abdelhamid A,Ali A,Bunn DK,Jennings A,John WG,Kerry S,Lindner G,Pfortmueller CA,Sjöstrand F,Walsh NP,Fairweather-Tait SJ,Potter JF,Hunter PR,Shepstone L

更新日期：2015-10-21 00:00:00

abstract：OBJECTIVES:The research aimed to support the effectiveness and necessity of the communication training and methodology introduced in the postgraduate pharmacy training and community pharmacy practice in Hungary. DESIGN:Two cross-sectional questionnaire surveys before and after the introduction of a methodological reco...

journal_title：BMJ open

authors： Szilvay A,Somogyi O,Meskó A,Szűcs-Polonkai K,Zelkó R,Hankó B

更新日期：2020-12-08 00:00:00

abstract：OBJECTIVE:To identify associations between the weight groups underweight (UW), overweight (OW) and obesity (OB) at 5 years of age and exposures related to pregnancy, anthropometric measures at birth, sociodemographic factors, and family health, anthropometric measures and habits. DESIGN:Regional cohort study. SETTING...

journal_title：BMJ open

authors： Donkor HM,Grundt JH,Júlíusson PB,Eide GE,Hurum J,Bjerknes R,Markestad T

更新日期：2017-08-18 00:00:00

abstract：OBJECTIVE:Lung cancer is increasingly recognised as a heterogeneous disease. Recent advances with targeted therapies for lung cancer with oncogenic mutations have greatly improved the prognosis for this subset of patients, yet little is known about their experiences. This study aimed to identify the needs and explore t...

journal_title：BMJ open

authors： Al Achkar M,Marchand L,Thompson M,Chow LQM,Revere D,Baldwin LM

更新日期：2020-03-23 00:00:00

abstract：INTRODUCTION:The development of malignant pleural effusion (MPE) results in disabling breathlessness, pain and reduced physical capability with treatment a palliative strategy. Ambulatory management of MPE has the potential to improve quality of life (QoL). The OPTIMUM trial is designed to determine whether full outpat...

journal_title：BMJ open

authors： Sivakumar P,Douiri A,West A,Rao D,Warwick G,Chen T,Ahmed L

更新日期：2016-10-18 00:00:00

abstract：OBJECTIVE:We aimed to epidemiologically assess rubella herd immunity as a function of time, age and gender in Japan, with reference to the recent 2012-2014 rubella epidemic. DESIGN:This study is a retrospective seroepidemiological analysis. MAIN OUTCOME MEASURES:The susceptible fraction of the population was examined...

journal_title：BMJ open

authors： Kinoshita R,Nishiura H

更新日期：2016-01-27 00:00:00

abstract：OBJECTIVES:To estimate the absolute cardiovascular disease (CVD) risk burden in a remote rural Bangladeshi population using the 'With' and 'Without' Cholesterol versions of the WHO/International Society of Hypertension (WHO/ISH) CVD risk assessment chart (particularly suitable for low and middle-income countries due to...

journal_title：BMJ open

authors： Fatema K,Zwar NA,Milton AH,Rahman B,Ali L

更新日期：2015-10-13 00:00:00

abstract：INTRODUCTION:Repetitive transcranial magnetic stimulation (rTMS), a non-invasive brain stimulation approach, might be a promising technique in the management of insomnia. A systematic review of the available literature on this topic is warranted. The systematic review described in this protocol aims to investigate the ...

journal_title：BMJ open

authors： He Y,Sun N,Wang Z,Zou W

更新日期：2019-07-16 00:00:00