Effectiveness of new legislation on partial sickness benefit on work participation: a quasi-experiment in Finland.

abstract：OBJECTIVES:Taxing sugar-sweetened beverages (SSBs) is now advocated, and implemented, in many countries as a measure to reduce the purchase and consumption of sugar to tackle obesity. To date, there has been little consideration of the potential impact that such a measure could have if extended to other sweet foods, su...

journal_title：BMJ open

authors： Smith RD,Cornelsen L,Quirmbach D,Jebb SA,Marteau TM

更新日期：2018-04-26 00:00:00

abstract：OBJECTIVES:To establish a database network for the study of alpha-1 antitrypsin deficiency (AATD) and compare the results to CT lung density as the most direct measure of emphysema. DESIGN:A central electronic database was established to permit the upload of anonymised patient data from remote sites. Prospectively col...

journal_title：BMJ open

authors： Crossley D,Stockley J,Bolton CE,Hopkinson NS,Mahadeva R,Steiner M,Wilkinson T,Hurst JR,Gooptu B,Stockley RA

更新日期：2020-06-30 00:00:00

abstract：INTRODUCTION:As a combination of visual stimulation and motor imagery, mirror visual feedback (MVF) is an effective treatment for motor impairment after stroke; however, few studies have investigated its effects on relevant cognitive processes such as visual perception and motor imagery. Camera-based MVF (camMVF) overc...

journal_title：BMJ open

authors： Ding L,Wang X,Guo X,Chen S,Wang H,Cui X,Rong J,Jia J

更新日期：2019-03-03 00:00:00

abstract：BACKGROUND:There is a growing body of evidence associating financial strain (FS) with poor health but most of this research has been cross-sectional and adult-focused. During the 'Great Recession' many UK households experienced increased FS. The primary aim of this study was to determine the impact of increased FS on c...

journal_title：BMJ open

authors： McKenna C,Law C,Pearce A

更新日期：2017-03-09 00:00:00

abstract：OBJECTIVES:To characterise the pattern of colonisation and serotypes of Streptococcus pneumoniae among patients with chronic obstructive pulmonary disease (COPD) who currently receive the 23-valent pneumococcal polysaccharide vaccine (PPV-23) according to vaccination status, use of antibiotics and steroids. To investig...

journal_title：BMJ open

authors： McCarthy H,Jackson M,Corcoran M,McElligott M,MacHale E,Sulaiman I,Cushen B,Costello RW,Humpreys H

更新日期：2017-07-09 00:00:00

abstract：INTRODUCTION:Pseudomonas aeruginosa (PA) has historically been one of the major causes of severe sepsis and death among neutropenic cancer patients. There has been a recent increase of multidrug-resistant PA (MDRPA) isolates that may determine a worse prognosis, particularly in immunosuppressed patients. The aim of thi...

journal_title：BMJ open

authors： Albasanz-Puig A,Gudiol C,Parody R,Tebe C,Akova M,Araos R,Bote A,Brunel AS,Calik S,Drgona L,García E,Hemmati P,Herrera F,Ibrahim KY,Isler B,Kanj S,Kern W,Maestro de la Calle G,Manzur A,Marin JI,Márquez-Gómez I,Ma

更新日期：2019-05-24 00:00:00

abstract：INTRODUCTION:Total mesorectal excision (TME) is the highly effective standard treatment for rectal cancer but is associated with significant morbidity and may be overtreatment for low-risk cancers. This study is designed to determine the feasibility of international recruitment in a study comparing organ-saving approac...

journal_title：BMJ open

authors： Rombouts AJM,Al-Najami I,Abbott NL,Appelt A,Baatrup G,Bach S,Bhangu A,Garm Spindler KL,Gray R,Handley K,Kaur M,Kerkhof E,Kronborg CJ,Magill L,Marijnen CAM,Nagtegaal ID,Nyvang L,Peters FP,Pfeiffer P,Punt C,Quirke P

更新日期：2017-12-28 00:00:00

abstract：INTRODUCTION:Colorectal cancer is the fourth most common type of cancer and the second most common cause of cancer-related deaths in the UK. The full blood count (FBC) is a blood test that may play a role in early detection of the disease. Previous studies have aimed to identify how levels of individual components, suc...

journal_title：BMJ open

authors： Virdee PS,Kirtley S,Elhussein L,Watkinson PJ,Holt TA,Birks J

更新日期：2019-12-16 00:00:00

abstract：OBJECTIVES:We investigated whether self-reported disability was associated with mortality in adults in rural Malawi. SETTING:Karonga Health and Demographic Surveillance Site (HDSS), Northern Malawi. PARTICIPANTS:All adults aged 18 and over residing in the HDSS were eligible to participate. During annual censuses in 2...

journal_title：BMJ open

authors： Prynn JE,Dube A,Mkandawire J,Koole O,Geis S,Mwaiyeghele E,Mwiba O,Price AJ,Kachiwanda L,Nyirenda M,Kuper H,Crampin AC

更新日期：2020-08-27 00:00:00

abstract：OBJECTIVES:This study aimed to identify intrauterine growth differences according to infertility treatment compared with spontaneous conception and to describe intrauterine growth trajectories. DESIGN:Retrospective cohort study. SETTING:A single primary and tertiary medical centre in Japan. PARTICIPANTS:This study i...

journal_title：BMJ open

authors： Shinohara S,Hirata S,Suzuki K

更新日期：2020-04-28 00:00:00

abstract：PURPOSE:Progression of stable coronary artery disease (CAD) towards acute coronary syndrome (ACS) is a dynamic and heterogeneous process with many intertwined constituents, in which a plaque destabilising sequence could lead to ACS within short time frames. Current CAD risk assessment models, however, are not designed ...

journal_title：BMJ open

authors： Oemrawsingh RM,Akkerhuis KM,Umans VA,Kietselaer B,Schotborgh C,Ronner E,Lenderink T,Liem A,Haitsma D,van der Harst P,Asselbergs FW,Maas A,Oude Ophuis AJ,Ilmer B,Dijkgraaf R,de Winter RJ,The SH,Wardeh AJ,Hermans W,Cr

更新日期：2016-12-23 00:00:00

abstract：OBJECTIVES:Bariatric surgery is the most clinically effective treatment for people with severe and complex obesity, however, the psychosocial outcomes are less clear. Follow-up care after bariatric surgery is known to be important, but limited guidance exists on what this should entail, particularly related to psycholo...

journal_title：BMJ open

authors： Coulman KD,MacKichan F,Blazeby JM,Donovan JL,Owen-Smith A

更新日期：2020-02-06 00:00:00

abstract：OBJECTIVES:To study the interplay between several indicators of social disadvantage and hospitalisations due to ambulatory care-sensitive conditions (ACSC) in 2011─2013. To evaluate whether the accumulation of preceding social disadvantage in one point of time or prolongation of social disadvantage had an effect on hos...

journal_title：BMJ open

authors： Lumme S,Manderbacka K,Arffman M,Karvonen S,Keskimaki I

更新日期：2020-08-26 00:00:00

abstract：INTRODUCTION:Reduction in low-density lipoprotein cholesterol (LDL-C) improves clinical outcomes in patients with coronary artery disease. However, rates of lipid-lowering medication adherence are far from ideal. Reducing dosage frequency from multiple dosing to once-daily dosing may improve patients' medication adhere...

journal_title：BMJ open

authors： Wu Z,Wu D,Jiang J,Chen A,Zheng DD,Li J,Dong Y,Chen Y

更新日期：2020-05-17 00:00:00

abstract：OBJECTIVES:To evaluate the cost-effectiveness of immediate treatment with ranibizumab in patients with neovascular age-related macular degeneration (nAMD) with good (better than 6/12) starting visual acuity compared with current UK clinical guidance of waiting until vision falls below 6/12 to begin treatment, using rea...

journal_title：BMJ open

authors： Butt T,Lee A,Lee C,Tufail A,UK AMD EMR Study Group.

更新日期：2015-05-05 00:00:00

abstract：PURPOSE:Pakistan is faced with an increasing prevalence of diabetes in addition to its existing high burden of tuberculosis (TB). Diabetes has a detrimental effect on treatment outcomes of patients with TB, which may hinder achieving the goals of the End-TB strategy by 2030. We conducted a prospective cohort study to d...

journal_title：BMJ open

authors： Mukhtar F,Butt ZA

更新日期：2016-12-02 00:00:00

abstract：OBJECTIVE:Previous studies that have found an increased risk for tuberculosis (TB) in people with diabetes mellitus (DM) have been conducted in segments of the population and have not adjusted for important potential confounders. We sought to determine the RR for TB in the presence of DM in a national population with d...

journal_title：BMJ open

authors： Dobler CC,Flack JR,Marks GB

更新日期：2012-02-13 00:00:00

abstract：INTRODUCTION:Tranexamic acid (TXA) is a synthetic derivative of the amino acid lysine that inhibits fibrinolysis by blocking lysine-binding sites on plasminogen, which contribute to reduced bleeding, the need for transfusion and mortality. Although there is reliable evidence of the efficacy of TXA, its effects on other...

journal_title：BMJ open

authors： Murao S,Nakata H,Yamakawa K

更新日期：2020-06-22 00:00:00

abstract：OBJECTIVE:To predict antibiotic use after initial treatment with ibuprofen using data from a randomised controlled trial comparing ibuprofen to pivmecillinam in the treatment of women with symptoms of an uncomplicated urinary tract infection (UTI). SETTING:16 sites in a primary care setting in Norway, Sweden and Denma...

journal_title：BMJ open

authors： Vik I,Mdala I,Bollestad M,Cordoba GC,Bjerrum L,Neumark T,Damsgaard E,Bærheim A,Grude N,Lindbaek M

更新日期：2020-08-30 00:00:00

abstract：:Objective To identify factors predicting early death in women with breast cancer. Design Cohort study. Setting 29 trusts across seven cancer networks in the North Thames area. Participants 15 037 women with primary breast cancer diagnosed between January 1996 and December 2005. Methods Logistic regression analyses...

journal_title：BMJ open

authors： Stapelkamp C,Holmberg L,Tataru D,Møller H,Robinson D

更新日期：2011-11-28 00:00:00

abstract：OBJECTIVES:The rate of total knee arthroplasty surgery (TKA) is rising in Australia despite varying impacts of TKA on physical function (PF) in population-based studies. There are potentially modifiable risk factors that could enhance PF after TKA, so we evaluated (1) the levels of PF in persons with TKA and the rest o...

journal_title：BMJ open

authors： Rogers KD,Blyth FM,March LM,Jorm L

更新日期：2013-07-08 00:00:00

abstract：OBJECTIVES:Injection drug use is the most important risk factor for the spread of HIV in China over the past two decades. People who use drugs (PWUD) who were diagnosed at an early stage with HIV have gradually developed AIDS. This study investigated the factors associated with disease progression following HIV diagnos...

journal_title：BMJ open

authors： Luo H,Sun M,Du J

更新日期：2019-07-03 00:00:00

abstract：INTRODUCTION:Cardiovascular disease (CVD) remains a major cause of morbidity and premature mortality globally. Despite the availability of low-cost evidence based medicines, there is a significant treatment gap in those with established or at high risk of CVD in the primary care setting. Pharmacist-based interventions ...

journal_title：BMJ open

authors： Chaudhri K,Hayek A,Liu H,Joshi R

更新日期：2019-08-05 00:00:00

abstract：INTRODUCTION:Many people residing in low-income and middle-income countries (LMICs) are regularly exposed to catastrophic healthcare expenditure. It is therefore pertinent that LMICs should finance their health systems in ways that ensure that their citizens can use needed healthcare services and are protected from pot...

journal_title：BMJ open

authors： Adebayo EF,Ataguba JE,Uthman OA,Okwundu CI,Lamont KT,Wiysonge CS

更新日期：2014-02-14 00:00:00

abstract：OBJECTIVES:To understand how the uptake of an extended primary care service in the evenings and weekend varied by day of week and over time. Secondary objectives were to understand patient demographics of users of the service and how these varied by type of appointment and to core hour users. DESIGN:Observational stud...

journal_title：BMJ open

authors： Whittaker W,Anselmi L,Nelson P,O'Donnell C,Ross N,Rothwell K,Hodgson D

更新日期：2019-09-05 00:00:00

abstract：OBJECTIVES:To determine the prescription of guideline recommended drug therapy in patients with stable coronary heart disease (sCHD) prior to percutaneous coronary intervention (PCI) in Germany and to examine the role of patient characteristics and features of regional healthcare supply in a multilevel model. DESIGN:S...

journal_title：BMJ open

authors： Frank-Tewaag J,Bleek J,Horenkamp-Sonntag D,Marschall U,Zeymer U,Donner-Banzhoff N,Sundmacher L

更新日期：2020-12-13 00:00:00

abstract：OBJECTIVES:To investigate different professionals' (nurse anaesthetists', anaesthesiologists', and postanaesthesia care unit nurses') descriptions of and reflections on the postoperative handover. DESIGN:A focus group interview study with a descriptive design using qualitative content analysis of transcripts. SETTING...

journal_title：BMJ open

authors： Randmaa M,Engström M,Swenne CL,Mårtensson G

更新日期：2017-08-04 00:00:00

abstract：INTRODUCTION:Much testing in medicine is aimed at healthy people to facilitate the early detection of health conditions. However, there is growing evidence that early detection is a double-edged sword that may cause harm in the form of overdiagnosis. The media can be seen as a major generator of consumer demand for hea...

journal_title：BMJ open

authors： O'Keeffe M,Barratt A,Maher C,Zadro J,Fabbri A,Jones M,Moynihan R

更新日期：2019-08-24 00:00:00

abstract：OBJECTIVE:To determine ethnic differences in the progression of chronic kidney disease (CKD) and risk of end-stage renal failure (ESRF) and death in adults with type 2 diabetes mellitus (T2DM), and to identify predictors of rapid renal decline. DESIGN:Observational community-based cohort study undertaken from 2006 to ...

journal_title：BMJ open

authors： Mathur R,Dreyer G,Yaqoob MM,Hull SA

更新日期：2018-03-27 00:00:00

abstract：INTRODUCTION:Periconception obesity is associated with a higher risk for adverse perinatal outcomes such as gestational diabetes mellitus, preeclampsia, large for gestational age, operative delivery and preterm birth. Lifestyle interventions during pregnancy have resulted in insufficient effects on reducing these perin...

journal_title：BMJ open

authors： Timmermans YEG,van de Kant KDG,Reijnders D,Kleijkers LMP,Dompeling E,Kramer BW,Zimmermann LJI,Steegers-Theunissen RPM,Spaanderman MEA,Vreugdenhil ACE

更新日期：2019-11-19 00:00:00