Safety of tranexamic acid in thrombotic adverse events and seizure in patients with haemorrhage: a protocol for a systematic review and meta-analysis.

abstract：INTRODUCTION:Patients with cancer often suffer from considerable distress. Life review is a process of recalling, evaluating and integrating life experiences to alleviate a sense of despair and achieve self-integrity. Empirical data have supported the fact that life review is an effective psychological intervention, bu...

journal_title：BMJ open

authors： Zhang X,Xiao H

更新日期：2018-12-06 00:00:00

abstract：INTRODUCTION:An ageing population has become an urgent concern for Asia in recent times. In nursing homes, polypharmacy has also become a compounding issue. Deprescribing practice is an evidence-based strategy to provide a better outcome in this group of patients; however, its implementation in nursing homes is often c...

journal_title：BMJ open

authors： Kua CH,Yeo CYY,Char CWT,Tan CWY,Tan PC,Mak VS,Lee SWH,Leong IY

更新日期：2017-05-09 00:00:00

abstract：OBJECTIVE:To explore the feasibility of health systems strengthening from the perspective of international healthcare implementers and donors in South Sudan. DESIGN:A qualitative interview study, with thematic analysis using the WHO health system building blocks framework. SETTING:South Sudan. PARTICIPANTS:17 health...

journal_title：BMJ open

authors： Jones A,Howard N,Legido-Quigley H

更新日期：2015-12-23 00:00:00

abstract：INTRODUCTION:Limb fractures in children are common yet there are few trials that compare treatments for these injuries. There is significant heterogeneity in the outcomes reported in the paediatric orthopaedic literature, which limits the ability to compare study results and draw firm conclusions. The aim of the CORE-K...

journal_title：BMJ open

authors： Marson BA,Manning JC,James M,Craxford S,Deshmukh SR,Ollivere BJ,CORE-Kids Group.

更新日期：2020-02-28 00:00:00

abstract：OBJECTIVE:To explore healthcare providers' views on barriers to and facilitators of use of the national family planning (FP) guideline for FP services in Amhara Region, Ethiopia. DESIGN:Qualitative study. SETTING:Nine health facilities including two hospitals, five health centres and two health posts in Amhara Region...

journal_title：BMJ open

authors： Tessema GA,Gomersall JS,Laurence CO,Mahmood MA

更新日期：2019-02-20 00:00:00

abstract：INTRODUCTION:The prevalence of emotional difficulties in young people is increasing. This upward trend is largely accounted for by escalating symptoms of anxiety and depression. As part of a public health response, there is increasing emphasis on universal prevention programmes delivered in school settings. This protoc...

journal_title：BMJ open

authors： Hayes D,Moore A,Stapley E,Humphrey N,Mansfield R,Santos J,Ashworth E,Patalay P,Bonin E,Boehnke JR,Deighton J

更新日期：2019-09-03 00:00:00

abstract：OBJECTIVE:To summarise the unfolding of the COVID-19 epidemic among slum dwellers and different social strata in the city of Buenos Aires during the first 20 weeks after the first reported case. DESIGN:Observational study using a time-series analysis. Natural experiment in a big city. SETTING:Population of the city o...

journal_title：BMJ open

authors： Macchia A,Ferrante D,Battistella G,Mariani J,González Bernaldo de Quirós F

更新日期：2021-01-20 00:00:00

abstract：PURPOSE:Chronic hypoxic and hypercapnic respiratory failure and obstructive sleep apnoea (OSA) are chronic diseases associated with decreased quality of life and increased mortality. The rationale behind the set up the retrospective nationwide DISCOVERY cohort was to study several questions including disease course and...

journal_title：BMJ open

authors： Palm A,Ågren K,Grote L,Ljunggren M,Midgren B,Sundh J,Theorell-Haglöw J,Ekström M

更新日期：2020-11-19 00:00:00

abstract：OBJECTIVES:This study aimed to determine the seroprevalence of Toxoplasma gondii (T. gondii) infection in pregnant women in Matehuala City, Mexico; and the associated risk factors. DESIGN:A cross-sectional study. SETTING:Matehuala City, Mexico. PARTICIPANTS:311 pregnant women. PRIMARY AND SECONDARY OUTCOME MEASURES...

journal_title：BMJ open

authors： Sandoval-Carrillo AA,Vértiz-Hernández AA,Salas-Pacheco JM,González-Lugo OE,Antuna-Salcido EI,Salas-Pacheco SM,Sánchez-Anguiano LF,Méndez-Hernández EM,Hernández-Tinoco J,Castellanos-Juárez FX,La-Llave-León O,Alvarado-Esquivel C

更新日期：2020-08-06 00:00:00

abstract：OBJECTIVE:The aim of the present study was to investigate the prevalence of abnormal cholesterol levels and to explore awareness of cholesterol values in an unselected sample of community-living adults. DESIGN:Cross-sectional survey. SETTING:Exhibitions, malls and health promotion campaigns across Italy. PARTICIPANT...

journal_title：BMJ open

authors： Marzetti E,Calvani R,Picca A,Sisto A,Tosato M,Martone AM,Ortolani E,Salini S,Pafundi T,Santoliquido A,Santoro L,Bernabei R,Landi F

更新日期：2018-06-30 00:00:00

abstract：OBJECTIVE:To identify research priorities of consumers and other stakeholders to inform Cochrane Reviews in 'health communication and participation' (including such concepts as patient experience, shared decision-making and health literacy). SETTING:International. PARTICIPANTS:We included anyone with an interest in h...

journal_title：BMJ open

authors： Synnot A,Bragge P,Lowe D,Nunn JS,O'Sullivan M,Horvat L,Tong A,Kay D,Ghersi D,McDonald S,Poole N,Bourke N,Lannin N,Vadasz D,Oliver S,Carey K,Hill SJ

更新日期：2018-05-08 00:00:00

abstract：OBJECTIVES:To evaluate whether family history of disease and pregravid lifestyle and cardiovascular risk factors are associated with subsequent stillbirth delivery. DESIGN:Prepregnancy cohort study. SETTING:Cohort Norway regional health surveys (1994-2003) linked to Medical Birth Registry of Norway for deliveries thr...

journal_title：BMJ open

authors： Egeland GM,Tell GS,Næss Ø,Igland J,Klungsøyr K

更新日期：2017-08-11 00:00:00

abstract：OBJECTIVE:To quantify and characterise missed opportunities for earlier HIV diagnosis in patients diagnosed with advanced HIV. DESIGN:A retrospective observational cohort study. SETTING:A central tertiary medical centre in Israel. MEASURES:The proportion of patients with advanced HIV, the proportion of missed opport...

journal_title：BMJ open

authors： Levy I,Maor Y,Mahroum N,Olmer L,Wieder A,Litchevski V,Mor O,Rahav G

更新日期：2016-11-10 00:00:00

abstract：OBJECTIVES:To derive priority weights for access to bariatric surgery for obese adults, from the perspective of the public. SETTING:Australian public hospital system. PARTICIPANTS:Adults (N=1994), reflecting the age and gender distribution of Queensland and South Australia. PRIMARY AND SECONDARY OUTCOME MEASURES:A d...

journal_title：BMJ open

authors： Whitty JA,Ratcliffe J,Kendall E,Burton P,Wilson A,Littlejohns P,Harris P,Krinks R,Scuffham PA

更新日期：2015-10-15 00:00:00

abstract：OBJECTIVE:Canada is among the few countries in which e-cigarettes containing nicotine are prohibited. To date, there is little evidence on the prevalence and patterns of use of e-cigarettes in markets with product bans. The current study examines e-cigarette use among a sample of non-smokers and smokers in Canada. DES...

journal_title：BMJ open

authors： Shiplo S,Czoli CD,Hammond D

更新日期：2015-08-26 00:00:00

abstract：OBJECTIVE:To define embarrassment and develop an understanding of the role of embarrassment in relation to cervical cancer screening and self-collected human papillomavirus (HPV) DNA testing in Uganda. DESIGN:Cross-sectional, qualitative study using semistructured one-to-one interviews and focus groups. PARTICIPANTS:...

journal_title：BMJ open

authors： Teng FF,Mitchell SM,Sekikubo M,Biryabarema C,Byamugisha JK,Steinberg M,Money DM,Ogilvie GS

更新日期：2014-04-11 00:00:00

abstract：OBJECTIVE:Lung cancer is increasingly recognised as a heterogeneous disease. Recent advances with targeted therapies for lung cancer with oncogenic mutations have greatly improved the prognosis for this subset of patients, yet little is known about their experiences. This study aimed to identify the needs and explore t...

journal_title：BMJ open

authors： Al Achkar M,Marchand L,Thompson M,Chow LQM,Revere D,Baldwin LM

更新日期：2020-03-23 00:00:00

abstract：OBJECTIVES:Lay people or non-pharmacy health workers with training could dispense antiretroviral therapy (ART) in resource-constrained countries, freeing up time for pharmacists to focus on more technical tasks. We assessed the effectiveness of such task-shifting in low-income and middle-income countries. METHOD:We co...

journal_title：BMJ open

authors： Mbeye NM,Adetokunboh O,Negussie E,Kredo T,Wiysonge CS

更新日期：2017-08-29 00:00:00

abstract：OBJECTIVE:To compare the effectiveness of the mobile e-Tabac Info Service (e-TIS) application (app) for helping adult smokers quit smoking with current practices. DESIGN:Pragmatic randomised controlled trial with a 1-year follow-up (2017-2018). SETTING:France, population-wide level. PARTICIPANTS:2806 adult smokers w...

journal_title：BMJ open

authors： Affret A,Luc A,Baumann C,Bergman P,Le Faou AL,Pasquereau A,Arwidson P,Alla F,Cambon L

更新日期：2020-10-27 00:00:00

abstract：OBJECTIVES:Healthcare professionals are expected to firmly ground their practice in sound evidence. That implies that they know and use evidence-based medicine (EBM). In this study, our aim was to know how often health professionals actually made use of EBM in their daily practice. DESIGN:A questionnaire survey of hea...

journal_title：BMJ open

authors： Lafuente-Lafuente C,Leitao C,Kilani I,Kacher Z,Engels C,Canouï-Poitrine F,Belmin J

更新日期：2019-03-30 00:00:00

abstract：OBJECTIVES:The aim of this study was to (1) demonstrate the development and testing of tools and procedures designed to monitor and assess the integrity of a complex intervention for chronic pain (COping with persistent Pain, Effectiveness Research into Self-management (COPERS) course); and (2) make recommendations bas...

journal_title：BMJ open

authors： Mars T,Ellard D,Carnes D,Homer K,Underwood M,Taylor SJ

更新日期：2013-11-15 00:00:00

abstract：OBJECTIVE:Nearly 100 000 primary total knee replacements (TKR) are performed in the UK annually. The primary aim of TKR is pain relief, but 10%-34% of patients report chronic pain. The aim of this systematic review was to evaluate the effectiveness of presurgical interventions in preventing chronic pain after TKR. DES...

journal_title：BMJ open

authors： Dennis J,Wylde V,Gooberman-Hill R,Blom AW,Beswick AD

更新日期：2020-01-20 00:00:00

abstract：OBJECTIVES:To systematically analyse the effect of pharmacological treatment of hypertension (HTN) on cognitive decline in older adults. METHODS:Randomised, placebo-controlled trials with a prespecified quantitative outcome of cognition and a pharmacological intervention for at least 12 months to treat HTN in older ad...

journal_title：BMJ open

authors： Gupta A,Perdomo S,Billinger S,Beddhu S,Burns J,Gronseth G

更新日期：2020-11-17 00:00:00

abstract：OBJECTIVES:Child dental caries is a global public health challenge with high prevalence and wide inequalities. A complex public health programme (Childsmile) was established. We aimed to evaluate the reach of the programme and its impact on child oral health. SETTING:Education, health and community settings, Scotland-...

journal_title：BMJ open

authors： Kidd JB,McMahon AD,Sherriff A,Gnich W,Mahmoud A,Macpherson LM,Conway DI

更新日期：2020-11-24 00:00:00

abstract：:Background Mini-sternotomy for isolated aortic valve replacement aims to reduce operative trauma hastening recovery and improving the cosmetic outcome of cardiac surgery. The short-term clinical benefits from the mini-sternotomy are presumed to arise because the incision is less extensive and the lower half of the che...

journal_title：BMJ open

authors： Khoshbin E,Prayaga S,Kinsella J,Sutherland FW

更新日期：2011-11-24 00:00:00

abstract：OBJECTIVES:Internalised homonegativity (IH) is hypothesised to be associated with HIV risk behaviour and HIV testing in men who have sex with men (MSM). We sought to determine the social and individual variables associated with IH and the associations between IH and HIV-related behaviours. DESIGN AND SETTING:We examin...

journal_title：BMJ open

authors： Ross MW,Berg RC,Schmidt AJ,Hospers HJ,Breveglieri M,Furegato M,Weatherburn P,European MSM Internet Survey (EMIS) Network.

更新日期：2013-02-04 00:00:00

abstract：OBJECTIVES:Although several rehabilitation programmes following hip arthroscopy for femoracetabular impingement (FAI) syndrome have been described, there are no clinical trials evaluating whether formal physiotherapy-prescribed rehabilitation improves recovery compared with self-directed rehabilitation. The objective o...

journal_title：BMJ open

authors： Bennell KL,Spiers L,Takla A,O'Donnell J,Kasza J,Hunter DJ,Hinman RS

更新日期：2017-06-23 00:00:00

abstract：STUDY OBJECTIVE:To evaluate the implementation of the Ohio Emergency and Acute Care Facility Opioids and Other Controlled Substances Prescribing Guidelines and their perceived impact on local policies and practice. METHODS:The study design was a cross-sectional survey of emergency department (ED) medical directors, or...

journal_title：BMJ open

authors： Penm J,MacKinnon NJ,Mashni R,Lyons MS,Hooker EA,Winstanley EL,Carlton-Ford S,Connelly C,Tolle E,Boone J,Koechlin K,Defiore-Hyrmer J

更新日期：2018-06-30 00:00:00

abstract：OBJECTIVES:To identify and describe the outcomes and facilitating processes of participation at 'Find Your Sense of Tumour' (FYSOT), a 2-day residential programme/conference for young people with cancer, from the perspective of professionals attending and patient representatives. DESIGN:Case study. SETTING:Observatio...

journal_title：BMJ open

authors： Martins A,Taylor RM,Morgan S,Fern LA

更新日期：2017-07-13 00:00:00

abstract：:​OBJECTIVES: To assess the impact of lower socioeconomic status on the outcome of major torso trauma patients under the single-payer system by the National Health Insurance (NHI) in Taiwan. ​DESIGN: A nationwide, retrospective cohort study. ​SETTING: An observational study from the NHI Research Database (NHIRD), invol...

journal_title：BMJ open

authors： Kuo LW,Fu CY,Liao CA,Liao CH,Hsieh CH,Wang SY,Chen SW,Cheng CT

更新日期：2019-11-12 00:00:00