Abstract:
OBJECTIVES:To compare the clinical, socioeconomic and demographic characteristics of individuals diagnosed with Neisseria gonorrhoeae (NG) in the community using a concomitant nucleic acid amplification test (NAAT, AptimaCombo2) as part of the (community-based) UK Chlamydia Screening Programme (CSP), with those diagnosed in hospital-based genitourinary medicine (GUM) services. DESIGN:A retrospective case note review of all 643 patients treated for NG at a GUM in north west England (January 2007-April 2009). PARTICIPANTS:All 643 treated for NG (including CSP cases, since all cases were referred to GUM for treatment). Limited data were available for 13 CSP cases who failed to attend GUM. PRIMARY OUTCOME MEASURE:Whether the case was detected in the community or GUM services. Predictors were demographics (age, gender, postcode for deprivation analysis), sexual history (eg, number of partners) and clinical factors (eg, culture positivity). RESULTS:131 cases were diagnosed by CSP (13 of whom did not attend GUM). A further four cases were contacts of these. The GUM caseload was thus inflated by 23% (from 521 to 643). Community cases were overwhelmingly female (85% vs 27% in GUM, p<0.001) and younger (87% females were <25 years vs 70% GUM females, p=0.001). Logistic regression analysis restricted to the target age of the CSP (<25 years) revealed that CSP cases, compared with GUM cases, were more likely to reside in deprived areas (adjusted OR=5.6, 95% CI 1.4 to 21.8 and 5.3, CI 1.7 to 16.6 for the most and second most deprived group respectively, compared with the averagely deprived group, p=0.037) and be asymptomatic (adjusted OR=1.9, CI 1.1 to 3.4, p=0.02). CONCLUSIONS:Community screening for NG led to a 79% increase in the number of infections detected in women aged <25 years. Screening is targeted at young people, and tends to disproportionately attract young women, a group under-represented at GUM. Screening also contributed further to case detection in deprived areas.
journal_name
BMJ Openjournal_title
BMJ openauthors
Cook PA,Evans-Jones J,Mallinson H,Wood M,Alloba F,Jones K,Strodtbeck S,Hanna-Bashara Ldoi
10.1136/bmjopen-2014-004862subject
Has Abstractpub_date
2014-03-14 00:00:00pages
e004862issue
3issn
2044-6055pii
bmjopen-2014-004862journal_volume
4pub_type
杂志文章相关文献
BMJ Open文献大全abstract:INTRODUCTION:Osteoarthritis (OA) pain is a major cause of long-term disability and chronic pain in the adult population. One in five patients does not receive satisfactory pain relief, which reflects the complexity of chronic pain and the current lack of understanding of mechanisms of chronic pain. Recently, duloxetine...
journal_title:BMJ open
pub_type: 杂志文章,随机对照试验
doi:10.1136/bmjopen-2016-014013
更新日期:2017-06-26 00:00:00
abstract:OBJECTIVE:To report outcomes of patients with localised prostate cancer (PCa) managed with active surveillance (AS) in a standard clinical setting. DESIGN:Single-centre, prospective, observational study. SETTING:Non-academic, average-size hospital in Switzerland. PARTICIPANTS:Prospective, observational study at a no...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2015-010191
更新日期:2016-02-17 00:00:00
abstract:OBJECTIVE:To describe health-related quality of life (HRQOL) and psychological well-being of children and adolescents at enrolment in a multidisciplinary community-based obesity programme and to determine association with ethnicity. This programme targeted indigenous people and those from most deprived households. Furt...
journal_title:BMJ open
pub_type: 杂志文章,随机对照试验
doi:10.1136/bmjopen-2016-015776
更新日期:2017-08-09 00:00:00
abstract:INTRODUCTION:HIV epidemic is increasing among men who have sex with men (MSM) in China, yet HIV testing uptake remains low. As an emerging approach, HIV self-testing (HIVST) has the potential to promote HIV testing coverage and frequency in this population. However, evidence of the effectiveness on implementation of HI...
journal_title:BMJ open
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1136/bmjopen-2018-024423
更新日期:2018-12-14 00:00:00
abstract:INTRODUCTION:Recent studies suggest that endoplasmic reticulum stress may play a critical role in the pathogenesis of amyotrophic lateral sclerosis (ALS) through an altered regulation of the proteostasis, the cellular pathway-balancing protein synthesis and degradation. A key mechanism is thought to be the dephosphoryl...
journal_title:BMJ open
pub_type: 杂志文章,随机对照试验
doi:10.1136/bmjopen-2016-015434
更新日期:2017-08-11 00:00:00
abstract:INTRODUCTION:Eye diseases and visual impairment more commonly affect elderly adults, thus, the majority of ophthalmic cohort studies have focused on older adults. Cohort studies on the ocular health of younger adults, on the other hand, have been few. The Raine Study is a longitudinal study that has been following a co...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2019-033440
更新日期:2020-03-25 00:00:00
abstract:OBJECTIVES:This study aims to examine the tracking and predictability of physical activity in old age from overall physical activity and participation in sport, recreational activity and walking in mid-life. DESIGN:Prospective population-based cohort study. SETTING:British Regional Heart Study participants recruited ...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2017-017378
更新日期:2017-09-21 00:00:00
abstract:OBJECTIVES:Socioeconomically deprived individuals with renal disease are less likely to receive a live-donor kidney transplant than less-deprived individuals. This qualitative study aimed to identify reasons for the observed socioeconomic disparity in live-donor kidney transplantation. DESIGN:A qualitative study using...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2015-010605
更新日期:2016-03-02 00:00:00
abstract:INTRODUCTION:Short-term psychodynamic psychotherapy (STPP) is an empirically supported treatment that is often used to treat depression. However, it is largely unclear if certain subgroups of depressed patients can benefit specifically from this treatment method. We describe the protocol for a systematic review and met...
journal_title:BMJ open
pub_type: 杂志文章,meta分析
doi:10.1136/bmjopen-2017-018900
更新日期:2018-02-20 00:00:00
abstract:OBJECTIVES:To investigate the role of socioeconomic status and psychological stress to potential associations between confidence in the future and a wide range of health-related behaviours. DESIGN:Web-based cross-sectional study including an 'Electronic Health Check' at the Finnish Happiness-Flourishing Study website ...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2012-002397
更新日期:2013-06-20 00:00:00
abstract:OBJECTIVE:Test accuracy of faecal calprotectin (FC) testing in primary care is inconclusive. We aimed to assess the test accuracy of FC testing in primary care and compare it to secondary care estimates for the detection of inflammatory bowel disease (IBD). METHODS:Systematic review and meta-analysis of test accuracy ...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2018-027428
更新日期:2019-03-08 00:00:00
abstract:BACKGROUND:The last two decades have seen an increase in literature reporting an increase in knowledge and use of contraceptives among individuals and couples in Kenya, as in the rest of Africa, but there is a dearth of information regarding knowledge about benefits of family planning (FP) in Kenya. OBJECTIVES:To asse...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2013-004643
更新日期:2014-03-18 00:00:00
abstract:OBJECTIVE:To describe the range and nature of available research regarding sources of information that patients access to inform their decisions about elective surgery. DESIGN:Scoping review. DATA SOURCES:Peer-reviewed studies published until February 2019 from the six scientific literature databases were searched an...
journal_title:BMJ open
pub_type: 杂志文章,评审
doi:10.1136/bmjopen-2018-023080
更新日期:2019-08-05 00:00:00
abstract:BACKGROUND:The Baby Friendly Hospital Initiative (BFHI) is a practice guideline for healthcare providers to promote breastfeeding and increase breastfeeding rates. OBJECTIVE:This study aimed to examine reported experiences and views on breastfeeding of women using prenatal and postnatal services, and opinions of staff...
journal_title:BMJ open
pub_type: 杂志文章,多中心研究
doi:10.1136/bmjopen-2016-012890
更新日期:2016-12-16 00:00:00
abstract:OBJECTIVE:To investigate the long-term effectiveness of a school-based intervention to improve physical activity and diet in children. DESIGN:Cluster-randomised controlled trial. SETTING:60 primary schools in the southwest of England. PARTICIPANTS:Primary school children who were aged 8-9 years at recruitment, 9-10 ...
journal_title:BMJ open
pub_type: 杂志文章,随机对照试验
doi:10.1136/bmjopen-2015-010957
更新日期:2016-11-24 00:00:00
abstract:OBJECTIVE:To describe the circumstances of the elderly with dementia and their caregivers' characteristics in order to examine factors related to activities of daily living (ADL) and household income to propose a long-term care policy for rural areas of Thailand. SETTING:A cross-sectional study at the household level ...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2019-032637
更新日期:2020-03-24 00:00:00
abstract:OBJECTIVES:Atrial fibrillation (AF) is the most common cardiac rhythm disorder with a significant health burden. The aim of this study was to characterise patients with recently diagnosed AF and to estimate the rates of comorbidities and outcome events requiring hospitalisation in routine clinical practice. DESIGN:Pha...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2013-003839
更新日期:2014-01-27 00:00:00
abstract:INTRODUCTION:Internet-based and mobile-based interventions (IMIs) provide an innovative and efficient self-management tool for mental health problems. This systematic review aims to summarise and critically evaluate studies addressing the effectiveness and feasibility of IMIs for normal and complicated grief in bereave...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2019-036034
更新日期:2020-04-22 00:00:00
abstract:INTRODUCTION:Trabeculotomy and combined trabeculotomy-trabeculectomy (CTT) are major surgical options for primary congenital glaucoma (PCG). However, it is unclear which of these two surgical procedures should be recommended as the optimum first-line treatment for PCG. This trial aims to determine whether the outcomes ...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2019-032957
更新日期:2020-02-25 00:00:00
abstract:OBJECTIVES:To understand the experiences of parents of infants who required surgery early in life. To identify messages and training needs for the extended clinical teams caring for these families-including paediatric surgeons, neonatologists, nurses, obstetricians, midwives and sonographers. SETTING:UK-wide interview...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2017-020921
更新日期:2018-06-30 00:00:00
abstract:INTRODUCTION:Human papillomavirus (HPV) is a causal agent of malignancies including cervical, vulvar, vaginal, penile, anal and oropharyngeal cancer, as well as benign conditions such as anogenital warts. HPV vaccination protects individuals against infections with the target HPV types and their clinical outcomes. Howe...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2020-039383
更新日期:2020-08-11 00:00:00
abstract:OBJECTIVES:Access to reproductive information and contraception (RIC) continues to be a critical unmet need in Tanzania and impedes the realisation of reproductive health rights. This study examined key sources of RIC and the factors influencing their uptake by women in Mbeya region of Tanzania. SETTING:This qualitati...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2019-036600
更新日期:2020-10-10 00:00:00
abstract:OBJECTIVES:Accreditation in France relies on a mandatory 4-year cycle of self-assessment and a peer review of 82 standards, among which 14 focus priority standards (FPS). Hospitals are also required to measure yearly quality indicators (QIs-5 in 2010). On advice given by the accreditation committee of HAS (Haute Autori...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2013-003289
更新日期:2013-08-30 00:00:00
abstract:OBJECTIVES:The clinical course and prognosis of follicular lymphoma (FL) are diverse and associated with the patient's immune response. We investigated the lymphocyte-to-monocyte ratio (LMR) and neutrophil-to-lymphocyte ratio (NLR) as prognostic factors in patients with FL, including those receiving radiotherapy. DESI...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2017-017904
更新日期:2017-11-03 00:00:00
abstract:OBJECTIVES:A recent study reported a large increase in the number of meniscal procedures from 2000 to 2011 in Denmark. We examined the nation-wide distribution of meniscal procedures performed in the private and public sector in Denmark since different incentives may be present and the use of these procedures may diffe...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2014-006659
更新日期:2015-02-24 00:00:00
abstract:OBJECTIVE:To determine the feasibility of therapy-based, risk-stratified follow-up guidelines for childhood and teenage cancer survivors by evaluating adverse health outcomes in a survivor cohort retrospectively assigned a risk category. DESIGN:Retrospective cohort study. SETTING:Tertiary level, single centre, paedia...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2012-002451
更新日期:2013-08-02 00:00:00
abstract:OBJECTIVES:Several ABILHAND Rasch-built manual ability scales were previously developed for chronic stroke (CS), cerebral palsy (CP), rheumatoid arthritis (RA), systemic sclerosis (SSc) and neuromuscular disorders (NMD). The present study aimed to explore the applicability of a generic manual ability scale unbiased by ...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2012-001807
更新日期:2012-10-31 00:00:00
abstract:OBJECTIVES:To describe the effect of in utero exposure to the buprenorphine+naloxone combination product in a rural and remote population. SETTING:A district hospital that services rural and remote, fly-in communities in Northwestern Ontario, Canada. PARTICIPANTS:A retrospective cohort study was conducted of 855 moth...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2016-011774
更新日期:2016-10-31 00:00:00
abstract:OBJECTIVES:To estimate the cost-effectiveness of a planned birth in a birth centre compared with alternative planned places of birth for low-risk women. In addition, a distinction has been made between different types of locations and integration profiles of birth centres. DESIGN:Economic evaluation based on a prospec...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2017-016960
更新日期:2017-09-11 00:00:00
abstract:OBJECTIVES:To identify the top 10 unanswered research questions for primary care patient safety research. DESIGN:A modified nominal group technique. SETTING:UK. PARTICIPANTS:Anyone with experience of primary care including: patients, carers and healthcare professionals. 341 patients and 86 healthcare professionals s...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2017-020870
更新日期:2018-02-28 00:00:00