Trabeculotomy versus combined trabeculotomy-trabeculectomy for primary congenital glaucoma: study protocol of a randomised controlled trial.

abstract：OBJECTIVES:Intention to treat (ITT) is an analytic strategy for reducing potential bias in treatment effects arising from missing data in randomised controlled trials (RCTs). Currently, no universally accepted definition of ITT exists, although many researchers consider it to require either no attrition or a strategy t...

journal_title：BMJ open

authors： Del Re AC,Maisel NC,Blodgett JC,Finney JW

更新日期：2013-11-12 00:00:00

abstract：:Objectives Diagnoses-specific sickness certification guidelines were recently introduced in Sweden. The aim of this study was to investigate to which extent general practitioners (GPs) used these guidelines and how useful they found them, 1 year after introduction. Design A cross-sectional questionnaire study. A comp...

journal_title：BMJ open

authors： Skånér Y,Nilsson GH,Arrelöv B,Lindholm C,Hinas E,Wilteus AL,Alexanderson K

更新日期：2011-12-20 00:00:00

abstract：OBJECTIVE:To report on the relative cost-effectiveness of total hip arthroplasty and resurfacing arthroplasty (replacement of articular surface of femoral head only) in patients with severe arthritis suitable for hip joint resurfacing arthroplasty. DESIGN:Cost-effectiveness analysis on an intention-to-treat basis of a...

journal_title：BMJ open

authors： Edlin R,Tubeuf S,Achten J,Parsons N,Costa M

更新日期：2012-10-12 00:00:00

abstract：OBJECTIVES:Malignant melanoma has high morbidity and mortality rates. Early diagnosis improves prognosis. Clinical prediction rules (CPRs) can be used to stratify patients with symptoms of suspected malignant melanoma to improve early diagnosis. We conducted a systematic review of CPRs for melanoma diagnosis in ambulat...

journal_title：BMJ open

authors： Harrington E,Clyne B,Wesseling N,Sandhu H,Armstrong L,Bennett H,Fahey T

更新日期：2017-03-06 00:00:00

abstract：OBJECTIVES:The aim of this study was to develop a single blood test that could determine gestational age and estimate the risk of preterm birth by measuring serum metabolites. We hypothesised that serial metabolic modelling of serum analytes throughout pregnancy could be used to describe fetal gestational age and proje...

journal_title：BMJ open

authors： Sylvester KG,Hao S,You J,Zheng L,Tian L,Yao X,Mo L,Ladella S,Wong RJ,Shaw GM,Stevenson DK,Cohen HJ,Whitin JC,McElhinney DB,Ling XB

更新日期：2020-12-02 00:00:00

abstract：INTRODUCTION:Policing practices are key drivers of HIV among people who inject drugs (PWID). This paper describes the protocol for the first study to prospectively examine the impact of a police education programme (PEP) to align law enforcement and HIV prevention. PEPs incorporating HIV prevention (including harm redu...

journal_title：BMJ open

authors： Strathdee SA,Arredondo J,Rocha T,Abramovitz D,Rolon ML,Patiño Mandujano E,Rangel MG,Olivarria HO,Gaines T,Patterson TL,Beletsky L

更新日期：2015-08-10 00:00:00

abstract：:Objective To identify factors predicting early death in women with breast cancer. Design Cohort study. Setting 29 trusts across seven cancer networks in the North Thames area. Participants 15 037 women with primary breast cancer diagnosed between January 1996 and December 2005. Methods Logistic regression analyses...

journal_title：BMJ open

authors： Stapelkamp C,Holmberg L,Tataru D,Møller H,Robinson D

更新日期：2011-11-28 00:00:00

abstract：BACKGROUND:The utilisation of available cross-European data for secondary data analyses on physical activity, sedentary behaviours and their underlying determinants may benefit from the wide variation that exists across Europe in terms of these behaviours and their determinants. Such reuse of existing data for further ...

journal_title：BMJ open

authors： Lakerveld J,Loyen A,Ling FCM,De Craemer M,van der Ploeg HP,O'Gorman DJ,Carlin A,Caprinica L,Kalter J,Oppert JM,Chastin S,Cardon G,Brug J,MacDonncha C

更新日期：2017-10-22 00:00:00

abstract：OBJECTIVE:To identify associations between the weight groups underweight (UW), overweight (OW) and obesity (OB) at 5 years of age and exposures related to pregnancy, anthropometric measures at birth, sociodemographic factors, and family health, anthropometric measures and habits. DESIGN:Regional cohort study. SETTING...

journal_title：BMJ open

authors： Donkor HM,Grundt JH,Júlíusson PB,Eide GE,Hurum J,Bjerknes R,Markestad T

更新日期：2017-08-18 00:00:00

abstract：INTRODUCTION AND OBJECTIVES:Macrolides have been associated with proarrhythmic properties, but the evidence is conflicting. We evaluated the risk of out-of-hospital cardiac arrest (OHCA) associated with specific macrolides in a retrospective study. Associations between specific macrolides and OHCA were examined by cond...

journal_title：BMJ open

authors： Hertz FB,Jensen A,Knudsen JD,Arpi M,Andersson C,Gislason GH,Køber L,Torp-Pedersen C,Lippert F,Weeke PE

更新日期：2018-02-23 00:00:00

abstract：OBJECTIVES:The clinical course and prognosis of follicular lymphoma (FL) are diverse and associated with the patient's immune response. We investigated the lymphocyte-to-monocyte ratio (LMR) and neutrophil-to-lymphocyte ratio (NLR) as prognostic factors in patients with FL, including those receiving radiotherapy. DESI...

journal_title：BMJ open

authors： Lee SF,Luque-Fernandez MA

更新日期：2017-11-03 00:00:00

abstract：OBJECTIVES:Despite evidence for an association between the built environment and physical activity, less evidence exists regarding relations between the built environment and sedentary behaviour. This study investigated the extent to which objectively assessed and self-reported neighbourhood walkability, in addition to...

journal_title：BMJ open

authors： McCormack GR,Mardinger C

更新日期：2015-11-25 00:00:00

abstract：OBJECTIVES:Studies on ethnic disparities in glycaemic control have been contradictory, and compromised by excessively broad categories of ethnicity and inadequate adjustment for socioeconomic differences. We aimed to study the effect of ethnicity on glycaemic control in a large cohort of patients with type 2 diabetes. ...

journal_title：BMJ open

authors： Rawshani A,Svensson AM,Rosengren A,Zethelius B,Eliasson B,Gudbjörnsdottir S

更新日期：2015-06-05 00:00:00

abstract：OBJECTIVE:The evaluation of discomfort in paediatric research is scarcely evidence-based. In this study, we make a start in describing children's self-reported discomfort during common medical research procedures and compare this with discomfort during dental check-ups which can be considered as a reference level of a ...

journal_title：BMJ open

authors： Staphorst MS,Benninga MA,Bisschoff M,Bon I,Busschbach JJV,Diederen K,van Goudoever JB,Haarman EG,Hunfeld JAM,Jaddoe VVW,de Jong KJM,de Jongste JC,Kindermann A,Königs M,Oosterlaan J,Passchier J,Pijnenburg MW,Reneman L,

更新日期：2017-08-01 00:00:00

abstract：OBJECTIVE:In caregivers of urban Aboriginal children, to determine the frequency of major stressful life events, the proportion who meet criteria for resilience, and factors that are associated with resilience. DESIGN:Cross-sectional survey. SETTING:Four Aboriginal Community Controlled Health Services located in urba...

journal_title：BMJ open

authors： Young C,Craig JC,Clapham K,Williams S,Williamson A,SEARCH investigators.

更新日期：2018-06-06 00:00:00

abstract：OBJECTIVE:To examine the prevalence, costs and trends (2010-2014) for 21 low-value inpatient procedures in a privately insured Australian patient cohort. DESIGN:We developed indicators for 21 low-value procedures from evidence-based lists such as Choosing Wisely, and applied them to a claims data set of hospital admis...

journal_title：BMJ open

authors： Chalmers K,Pearson SA,Badgery-Parker T,Brett J,Scott IA,Elshaug AG

更新日期：2019-03-05 00:00:00

abstract：BACKGROUND:The last two decades have seen an increase in literature reporting an increase in knowledge and use of contraceptives among individuals and couples in Kenya, as in the rest of Africa, but there is a dearth of information regarding knowledge about benefits of family planning (FP) in Kenya. OBJECTIVES:To asse...

journal_title：BMJ open

authors： Mutombo N,Bakibinga P,Mukiira C,Kamande E

更新日期：2014-03-18 00:00:00

abstract：OBJECTIVES:This study aimed to identify those at high risk of poor mental health among nursing students and to examine the relationships and consistency among five mental health assessments. DESIGN:A cross-sectional design with purposive sampling was used. Four mental health screening tools plus previous mental health...

journal_title：BMJ open

authors： Hsiung DY,Tsai CL,Chiang LC,Ma WF

更新日期：2019-06-25 00:00:00

abstract：INTRODUCTION:Exposure to secondhand smoke (SHS) increases children's risk of acquiring chest and ear infections, tuberculosis, meningitis and asthma. Smoking bans in public places (where implemented) have significantly reduced adults' exposure to SHS. However, for children, homes remain the most likely place for them t...

journal_title：BMJ open

authors： Siddiqi K,Huque R,Jackson C,Parrott S,Dogar O,Shah S,Thomson H,Sheikh A

更新日期：2015-08-25 00:00:00

abstract：OBJECTIVE:The first is to estimate the prevalence of dyslipidaemia (hypercholesterolaemia, hypertriglyceridaemia, high low-density lipoprotein (LDL) level and low high-density lipoprotein (HDL) level), as well as the mean levels of total cholesterol, triglyceride, LDL and HDL, in the urban and rural Yangon Region, Myan...

journal_title：BMJ open

authors： Htet AS,Kjøllesdal MK,Aung WP,Moe Myint AN,Aye WT,Wai MM,Nu TT,Hla EM,Soe PP,Tun NWY,Angela N,Khaing MM,Htoo AK,Tun S,Thitsar P,Lwin T,Wai SS,Aung TT,Thant KA,Aung Po WW,Gauzam ST,Naing TT,Tun TM,Myint KS,

更新日期：2017-11-15 00:00:00

abstract：INTRODUCTION:Physically active cancer survivors have substantially less cancer recurrence and improved survival compared with those who are inactive. However, the majority of survivors (70%-90%) are not meeting the physical activity (PA) guidelines. There are also significant geographic inequalities in cancer survival ...

journal_title：BMJ open

authors： Hardcastle SJ,Hince D,Jiménez-Castuera R,Boyle T,Cavalheri V,Makin G,Tan P,Salfinger S,Tan J,Mohan GR,Levitt M,Cohen PA,Saunders C,Platell C

更新日期：2019-05-24 00:00:00

abstract：OBJECTIVES:To investigate the association between psychosocial, sociodemographic and material determinants of positive mental health in Europe. DESIGN:Cross-sectional analysis of survey data. SETTING:34 European countries. PARTICIPANTS:Representative Europe-wide sample consisting of 21 066 men and 22 569 women aged ...

journal_title：BMJ open

authors： Dreger S,Buck C,Bolte G

更新日期：2014-05-28 00:00:00

abstract：:Objectives Eosinophilic oesophagitis (EO) shows eosinophilic infiltration of the mucosa and can present with symptoms indistinguishable from gastrooesophageal reflux disease (GORD). The authors describe the clinical, endoscopic and histopathological features of all cases of histological EO presenting during 2007-2008 ...

journal_title：BMJ open

authors： Cohen MC,Rao P,Thomson M,Al-Adnani M

更新日期：2012-01-12 00:00:00

abstract：OBJECTIVES:A Demographic and Health Platform was established in Magude in 2015, prior to the deployment of a project aiming to evaluate the feasibility of malaria elimination in southern Mozambique, named the Magude project. This platform aimed to inform the design, implementation and evaluation of the Magude project, ...

journal_title：BMJ open

authors： Galatas B,Nhacolo A,Marti H,Munguambe H,Jamise E,Guinovart C,Cirera L,Amone F,Macete E,Bassat Q,Rabinovich R,Alonso P,Aide P,Saute F,Sacoor C

更新日期：2020-05-05 00:00:00

abstract：BACKGROUND:Kawasaki disease (KD) is a self-limited acute systemic vasculitis of unknown aetiology that predominantly affects infants and young children eventually associated with immunological abnormalities. Coeliac disease (CD) is an inflammatory autoimmune disease characterised by a permanent gluten intolerance, whic...

journal_title：BMJ open

authors： Dos Santos Domingues A,Selleski N,Uenishi RH,Medeiros Ribeiro de Magalhães C,Gandolfi L,Pratesi CB

更新日期：2018-02-14 00:00:00

abstract：INTRODUCTION:Delirium is very common in patients admitted to intensive care unit (ICU), and may worsen survival in these patients. Several meta-analyses have evaluated the antidelirium effects of dexmedetomidine in ICU patients, but their findings were inconsistent. Recently, several large multicentre randomised clinic...

journal_title：BMJ open

authors： Sun R,Wang S,Li S,Yang C,Zhao Y,Luo A

更新日期：2019-04-03 00:00:00

abstract：:​OBJECTIVES: To assess the impact of lower socioeconomic status on the outcome of major torso trauma patients under the single-payer system by the National Health Insurance (NHI) in Taiwan. ​DESIGN: A nationwide, retrospective cohort study. ​SETTING: An observational study from the NHI Research Database (NHIRD), invol...

journal_title：BMJ open

authors： Kuo LW,Fu CY,Liao CA,Liao CH,Hsieh CH,Wang SY,Chen SW,Cheng CT

更新日期：2019-11-12 00:00:00

abstract：OBJECTIVE:This study assessed the incidence of tuberculosis (TB) and its predictors among adults living with HIV/AIDS in government health facilities in north-east Ethiopia. SETTING:A 5-year retrospective cohort study was conducted from May to June 2015 on 451 adult HIV/AIDS-infected individuals who enrolled in the HI...

journal_title：BMJ open

authors： Ahmed A,Mekonnen D,Shiferaw AM,Belayneh F,Yenit MK

更新日期：2018-02-06 00:00:00

abstract：INTRODUCTION:Chronic heart failure (CHF) is a heterogeneous condition requiring complex treatment from diverse healthcare services. An increasingly holistic understanding of healthcare has resulted in contextual factors such as perceived quality of care, as well as patients' acceptance, preferences and subjective expec...

journal_title：BMJ open

authors： Dieckelmann M,Reinhardt F,Jeitler K,Semlitsch T,Plath J,Gerlach FM,Siebenhofer A,Petersen JJ

更新日期：2019-02-19 00:00:00

abstract：INTRODUCTION:Fetal growth restriction (FGR) is a serious pregnancy complication, associated with increased rates of perinatal death and morbidity among survivors. Most commonly FGR results from placental insufficiency, where the placenta fails to deliver the oxygen and nutrients required for normal fetal growth. This l...

journal_title：BMJ open

authors： Palmer KR,Mockler JC,Davies-Tuck ML,Miller SL,Goergen SK,Fahey MC,Anderson PJ,Groom KM,Wallace EM

更新日期：2019-06-22 00:00:00