Observational study of the safety of buprenorphine+naloxone in pregnancy in a rural and remote population.

abstract：CONTEXT AND OBJECTIVE:Standards for clinical practice guidelines require explicit statements regarding how values and preferences influence recommendations. However, no cancer screening guideline has addressed the key question of what magnitude of benefit people require to undergo screening, given its harms and burdens...

journal_title：BMJ open

authors： Helsingen LM,Zeng L,Siemieniuk RA,Lytvyn L,Vandvik PO,Agoritsas T,Bretthauer M,Guyatt G

更新日期：2020-12-02 00:00:00

abstract：OBJECTIVE:The purpose of this meta-analysis was to evaluate the association between enlarged right atrial area (RAA), as measured by echocardiography, and prognosis of patients with pulmonary arterial hypertension (PAH). DESIGN:Systematic review and meta-analysis. DATA SOURCES:To identify potential publications, a co...

journal_title：BMJ open

authors： Liu K,Zhang C,Chen B,Li M,Zhang P

更新日期：2020-09-22 00:00:00

abstract：INTRODUCTION:Maternal and perinatal death surveillance and response (MPDSR), or any related form of audit, is a systematic process used to prevent future maternal and perinatal deaths. While the existence of MPDSR policies is routinely measured, measurement and understanding of policy implementation has lagged behind. ...

journal_title：BMJ open

authors： Kinney MV,Walugembe DR,Wanduru P,Waiswa P,George AS

更新日期：2019-11-27 00:00:00

abstract：INTRODUCTION:Knee osteoarthritis (OA) is one of the most common chronic diseases worldwide and is associated with significant pain and disability. Clinical practice guidelines consistently recommend weight management as a core aspect of care for overweight and obese patients with knee OA; however, provision of such car...

journal_title：BMJ open

authors： O'Brien KM,Wiggers J,Williams A,Campbell E,Wolfenden L,Yoong S,Robson EK,McAuley J,Haskins R,Kamper SJ,Williams C

更新日期：2016-03-03 00:00:00

abstract：OBJECTIVE:Podoconiosis is a neglected tropical disease characterised by a slowly progressive swelling of the foot and lower leg. It is prevalent among subsistence barefoot farmers who live and work in highland areas of the tropics. This study was conducted in Wayu Tuka 'woreda' (district), western Ethiopia to determine...

journal_title：BMJ open

authors： Bekele K,Deribe K,Amberbir T,Tadele G,Davey G,Samuel A

更新日期：2016-09-26 00:00:00

abstract：OBJECTIVES:Physicians are a commonly targeted group in health research surveys, but their response rates are often relatively low. The goal of this paper was to evaluate the effect of unconditional incentives in the form of a coffee card on physician postal survey response rates. DESIGN:Following 13 key informant inte...

journal_title：BMJ open

authors： Abdulaziz K,Brehaut J,Taljaard M,Émond M,Sirois MJ,Lee JS,Wilding L,Perry JJ

更新日期：2015-02-18 00:00:00

abstract：OBJECTIVES:A Demographic and Health Platform was established in Magude in 2015, prior to the deployment of a project aiming to evaluate the feasibility of malaria elimination in southern Mozambique, named the Magude project. This platform aimed to inform the design, implementation and evaluation of the Magude project, ...

journal_title：BMJ open

authors： Galatas B,Nhacolo A,Marti H,Munguambe H,Jamise E,Guinovart C,Cirera L,Amone F,Macete E,Bassat Q,Rabinovich R,Alonso P,Aide P,Saute F,Sacoor C

更新日期：2020-05-05 00:00:00

abstract：:Background Although recent genome-wide association studies have identified several genetic variants contributing to the complex aetiology of multiple sclerosis (MS), expression and functional studies are required to further understand its molecular basis. Objectives To identify genes and pathways with differential ex...

journal_title：BMJ open

authors： Kemppinen AK,Kaprio J,Palotie A,Saarela J

更新日期：2011-07-18 00:00:00

abstract：OBJECTIVES:This study examines the impact of the type of method used on the estimation of the burden of diseases. DESIGN:Comparison of methods of estimating disease burden. SETTING:Four metrics of burden of disease estimation, namely, years of potential life lost (YPLL), non-age weighted years of life lost (YLL) with...

journal_title：BMJ open

authors： Egunsola O,Raubenheimer J,Buckley N

更新日期：2019-08-18 00:00:00

abstract：INTRODUCTION:Metabolic disorder and high blood pressure are common complications globally, and specifically among people living with HIV (PLHIV). Diabetes, metabolic syndrome and hypertension are major risk factors for cardiovascular diseases and their related complications. However, the burden of metabolic syndrome, d...

journal_title：BMJ open

authors： Todowede OO,Sartorius B

更新日期：2017-07-09 00:00:00

abstract：OBJECTIVE:To evaluate accuracy of content and readability level of English Wikipedia articles on cardiovascular diseases, using quality and readability tools. METHODS:Wikipedia was searched on the 6 October 2013 for articles on cardiovascular diseases. Using a modified DISCERN (DISCERN is an instrument widely used in ...

journal_title：BMJ open

authors： Azer SA,AlSwaidan NM,Alshwairikh LA,AlShammari JM

更新日期：2015-10-06 00:00:00

abstract：OBJECTIVES:This systematic review aims to evaluate evidence on the effectiveness of sexual and reproductive health (SRH) interventions delivered in humanitarian crises. SETTING:Crisis affected low-income or middle-income countries. PARTICIPANTS:Crisis-affected populations in low-income or middle-income countries. ME...

journal_title：BMJ open

authors： Warren E,Post N,Hossain M,Blanchet K,Roberts B

更新日期：2015-12-18 00:00:00

abstract：INTRODUCTION:Catatonia arises from serious mental, medical, neurological or toxic conditions. The prevalence range depends on the setting and the range is anything from 7% to 63% in other countries. South African prevalence rates are currently unknown. The proposed study is a quantitative descriptive study using the Bu...

journal_title：BMJ open

authors： Zingela Z,Stroud L,Cronje J,Fink M,van Wyk S

更新日期：2020-11-06 00:00:00

abstract：OBJECTIVE:Leptin is a pleiotropic hormone associated with learning and memory via brain receptors. However, elevated plasma leptin levels may impair cognitive and memory functions. Since individual differences in memory performance affect students' ability to learn, we aimed to study the relation between leptin status ...

journal_title：BMJ open

authors： Correa-Burrows P,Blanco E,Reyes M,Castillo M,Peirano P,Algarín C,Lozoff B,Gahagan S,Burrows R

更新日期：2016-10-18 00:00:00

abstract：INTRODUCTION:Dental caries (tooth decay) is a common disease in which the products of sugar metabolism by certain bacteria that populate the tooth surface induce the development and progression of lesions (cavities). This is a phase II single-centre randomised, double-blind, active-controlled, parallel-group trial to a...

journal_title：BMJ open

authors： Milgrom P,Tut O,Rothen M,Mancl L,Gallen M,Tanzer JM

更新日期：2017-06-30 00:00:00

abstract：INTRODUCTION:Postnatal mental health problems, which are an international public health priority, are a suitable target for preventive approaches. The financial burden of these disorders is borne across sectors in society, including health, early childhood, education, justice and the workforce. This paper describes the...

journal_title：BMJ open

authors： Ride J,Rowe H,Wynter K,Fisher J,Lorgelly P

更新日期：2014-10-03 00:00:00

abstract：INTRODUCTION:Process evaluations are conducted alongside research projects to identify the context, impact and consequences of research, determine whether it was conducted per protocol and to understand how, why and for whom an intervention is effective. We present a process evaluation protocol for the Getting it Right...

journal_title：BMJ open

authors： Farnbach S,Evans J,Eades AM,Gee G,Fernando J,Hammond B,Simms M,DeMasi K,Hackett M

更新日期：2017-11-03 00:00:00

abstract：INTRODUCTION:Complex coronary artery disease (left main and three-vessel disease) carries high risks of adverse events and cost burden. However, in China, little is known about which patients are directed toward which treatment strategies and what outcomes are being achieved. METHODS AND ANALYSIS:Using the China PEACE...

journal_title：BMJ open

authors： Rao C,Bongiovanni T,Li X,Gao H,Zhang H,Li J,Zhao Y,Yuan X,Hua K,Hu S,Krumholz HM,Jiang L,Zheng Z,China PEACE Collaborative Group.

更新日期：2016-02-15 00:00:00

abstract：OBJECTIVE:To consolidate and assess information on counterfeit medicines subject to pharmaceutical alerts issued by the Peruvian Medicines Regulatory Authority over 18 years (1997-2014) of health monitoring and enforcement. DESIGN:A retrospective review of drug alerts. SETTING:A search of the website of the General D...

journal_title：BMJ open

authors： Medina E,Bel E,Suñé JM

更新日期：2016-04-04 00:00:00

abstract：BACKGROUND:The Baby Friendly Hospital Initiative (BFHI) is a practice guideline for healthcare providers to promote breastfeeding and increase breastfeeding rates. OBJECTIVE:This study aimed to examine reported experiences and views on breastfeeding of women using prenatal and postnatal services, and opinions of staff...

journal_title：BMJ open

authors： Mosher C,Sarkar A,Hashem AA,Hamadah RE,Alhoulan A,AlMakadma YA,Khan TA,Al-Hamdani AK,Senok A

更新日期：2016-12-16 00:00:00

abstract：OBJECTIVES:To assess people's procedural preferences for making medical surrogate decisions, from the perspectives of both a potential surrogate and an incapacitated patient. DESIGN:Computer-assisted telephone interviews. Respondents were randomly assigned either the role of an incapacitated patient or that of a poten...

journal_title：BMJ open

authors： Frey R,Herzog SM,Hertwig R

更新日期：2018-07-25 00:00:00

abstract：OBJECTIVES:To explore perceptions of superslims packaging, including compact 'lipstick' packs, in line with 3 potential impacts identified within the impact assessment of the European Union (EU) Tobacco Products Directive: appeal, harm perceptions and the seriousness of warning of health risks. DESIGN:Qualitative focu...

journal_title：BMJ open

authors： Ford A,Moodie C,Purves R,MacKintosh AM

更新日期：2016-01-08 00:00:00

abstract：OBJECTIVE:The Yale Global Tic Severity Scale (YGTSS) is the most commonly used clinician-rated evaluation tool for Tourette syndrome (TS), with established reliability and validity. This study aims to determine whether the YGTSS is a valid parent-reported assessment in the TS population. DESIGN:A prospective cohort st...

journal_title：BMJ open

authors： Ho CS,Huang JY,Yang CH,Lin YJ,Huang MY,Su YC

更新日期：2020-08-20 00:00:00

abstract：OBJECTIVE:This paper explores what aspects of a multicomponent intervention were deemed strengths and weaknesses by teenagers and the local council when promoting physical activity to young people. DESIGN:Qualitative findings at 12 months from a mixed method randomised control trial. METHODS:Active Children Through I...

journal_title：BMJ open

authors： James M,Christian D,Scott S,Todd C,Stratton G,Demmler J,McCoubrey S,Halcox J,Audrey S,Ellins EA,Irvine E,Brophy S

更新日期：2019-05-10 00:00:00

abstract：OBJECTIVES:This study was designed to investigate the effect of alcohol intoxication on clinical presentation of hospitalised adult trauma patients at a Level I trauma centre using propensity score matching. DESIGN:Cross-sectional study. SETTING:Taiwan. PARTICIPANTS:Detailed data of 929 hospitalised adult trauma pat...

journal_title：BMJ open

authors： Peng SH,Hsu SY,Kuo PJ,Rau CS,Cheng YA,Hsieh CH

更新日期：2016-11-01 00:00:00

abstract：INTRODUCTION:Depression is a common and disabling health problem that contributes to an important social and economic burden, particularly among the working age population. The deleterious effect of psychosocial work factors on depression has been documented. However, the most recent systematic reviews had restrictive ...

journal_title：BMJ open

authors： Duchaine CS,Aubé K,Gilbert-Ouimet M,Bruno Pena Gralle AP,Vezina M,Ndjaboue R,Massamba VK,Trudel X,Lesage A,Moore L,Laurin D,Brisson C

更新日期：2019-11-04 00:00:00

abstract：OBJECTIVES:To identify the determinants of antenatal care (ANC) utilisation in sub-Saharan Africa. DESIGN:Systematic review. DATA SOURCES:Databases searched were PubMed, OVID, EMBASE, CINAHL and Web of Science. ELIGIBILITY CRITERIA:Primary studies reporting on determinants of ANC utilisation following multivariate a...

journal_title：BMJ open

authors： Okedo-Alex IN,Akamike IC,Ezeanosike OB,Uneke CJ

更新日期：2019-10-07 00:00:00

abstract：OBJECTIVE:Spanish primary healthcare teams have the responsibility of performing health-promoting community activities (CAs), although such activities are not widespread. Our aim was to identify the factors related to participation in those activities. DESIGN:Two case-control studies. SETTING:Performed in primary car...

journal_title：BMJ open

authors： March S,Ripoll J,Jordan Martin M,Zabaleta-Del-Olmo E,Benedé Azagra CB,Elizalde Soto L,Vidal MC,Bauzà Amengual ML,Planas Juan T,Pérez Mariano DM,Llull Sarralde M,Ruiz-Giménez JL,Bajo Viñas R,Solano Villarubia C,Rodriguez Bajo

更新日期：2017-10-08 00:00:00

abstract：OBJECTIVES:Defects in the human thyroid peroxidase (TPO) gene are reported to be one of the causes of congenital hypothyroidism (CH) due to dyshormonogenesis. The aim of this study was to examine the TPO mutation spectrum and prevalence among patients with CH in the Guangxi Zhuang Autonomous Region of China and to defi...

journal_title：BMJ open

authors： Fu C,Xie B,Zhang S,Wang J,Luo S,Zheng H,Su J,Hu X,Chen R,Fan X,Luo J,Gu X,Chen S

更新日期：2016-05-12 00:00:00

abstract：OBJECTIVE:Screening is a key strategy to address the rising burden of chronic kidney disease (CKD) in low-income and middle-income countries. However, there are few reports regarding the implementation of screening programmes in resource-limited settings. The objectives of this study are to (1) to share programmatic ex...

journal_title：BMJ open

authors： Flood D,Garcia P,Douglas K,Hawkins J,Rohloff P

更新日期：2018-01-21 00:00:00