Prevalence of metabolic syndrome, discrete or comorbid diabetes and hypertension in sub-Saharan Africa among people living with HIV versus HIV-negative populations: a systematic review and meta-analysis protocol.

Abstract:

INTRODUCTION:Metabolic disorder and high blood pressure are common complications globally, and specifically among people living with HIV (PLHIV). Diabetes, metabolic syndrome and hypertension are major risk factors for cardiovascular diseases and their related complications. However, the burden of metabolic syndrome, discrete or comorbid diabetes and hypertension in PLHIV compared with HIV-negative population has not been quantified. This review and meta-analysis aims to compare and analyse the prevalence of these trio conditions between HIV-negative and HIV-positive populations in sub-Saharan Africa (SSA). METHODS AND ANALYSIS:The Preferred Reporting Items for Systematic Reviews and Meta-Analysis statement guides the methods for this study. Eligibility criteria will be published original articles (English and French language) from SSA that present the prevalence of metabolic syndrome, discrete and/or comorbid diabetes, and hypertension comparisons between PLHIV and HIV-negative populations. The following databases will be searched from January 1990 to February 2017: PubMed/Medline, EBSCOhost, Web of Science, Google Scholar, Scopus, African Index Medicus and Cochrane Database of Systematic Reviews. Eligibility screening and data extraction will be conducted independently by two reviewers, and disagreements resolved by an independent reviewer. Methodological quality and risk of bias will be assessed for individual included studies, while meta-analysis will be used to estimate study outcomes prevalence according to subgroups. Sensitivity analysis will also be performed to further test the robustness of the findings. ETHICS AND DISSEMINATION:This proposed study does not require ethical approval. The results will be published as a scientific article in a peer-reviewed journal, and presented at conferences and to relevant health agencies. TRIAL REGISTRATION NUMBER:PROSPERO registration number (CRD42016045727).

journal_name

BMJ Open

journal_title

BMJ open

authors

Todowede OO,Sartorius B

doi

10.1136/bmjopen-2017-016602

subject

Has Abstract

pub_date

2017-07-09 00:00:00

pages

e016602

issue

7

issn

2044-6055

pii

bmjopen-2017-016602

journal_volume

7

pub_type

杂志文章,meta分析

相关文献

BMJ Open文献大全
  • Supportive text messages for patients with alcohol use disorder and a comorbid depression: a protocol for a single-blind randomised controlled aftercare trial.

    abstract:INTRODUCTION:Alcohol use disorders (AUDs) and mood disorders commonly co-occur, and are associated with a range of negative outcomes for patients. Mobile phone technology has the potential to provide personalised support for such patients and potentially improve outcomes in this difficult-to-treat cohort. The aim of th...

    journal_title:BMJ open

    pub_type: 杂志文章,随机对照试验

    doi:10.1136/bmjopen-2016-013587

    authors: Hartnett D,Murphy E,Kehoe E,Agyapong V,McLoughlin DM,Farren C

    更新日期:2017-05-29 00:00:00

  • What factors are critical to attracting NHS foundation doctors into specialty or core training? A discrete choice experiment.

    abstract:OBJECTIVES:Multiple personal and work-related factors influence medical trainees' career decision-making. The relative value of these diverse factors is under-researched, yet this intelligence is crucially important for informing medical workforce planning and retention and recruitment policies. Our aim was to investig...

    journal_title:BMJ open

    pub_type: 杂志文章

    doi:10.1136/bmjopen-2017-019911

    authors: Scanlan GM,Cleland J,Johnston P,Walker K,Krucien N,Skåtun D,NHS Education for Scotland.

    更新日期:2018-03-12 00:00:00

  • Perspectives of health workers on the referral of women with obstetric complications: a qualitative study in rural Sierra Leone.

    abstract:OBJECTIVES:Sierra Leone has one of the highest maternal mortality ratios in the world. Timely and well-coordinated referrals are necessary to reduce delays in providing adequate care for women with obstetric complications. This study describes factors affecting timely and adequate referral of women with obstetric compl...

    journal_title:BMJ open

    pub_type: 杂志文章

    doi:10.1136/bmjopen-2020-041746

    authors: Proos R,Mathéron H,Vas Nunes J,Falama A,Sery Kamal P,Grobusch MP,van den Akker T

    更新日期:2020-12-10 00:00:00

  • Comparisons of neurodegeneration over time between healthy ageing and Alzheimer's disease cohorts via Bayesian inference.

    abstract:OBJECTIVES:In recent years, large-scale longitudinal neuroimaging studies have improved our understanding of healthy ageing and pathologies including Alzheimer's disease (AD). A particular focus of these studies is group differences and identification of participants at risk of deteriorating to a worse diagnosis. For t...

    journal_title:BMJ open

    pub_type: 杂志文章

    doi:10.1136/bmjopen-2016-012174

    authors: Cespedes MI,Fripp J,McGree JM,Drovandi CC,Mengersen K,Doecke JD

    更新日期:2017-02-07 00:00:00

  • Screening for chronic kidney disease in a community-based diabetes cohort in rural Guatemala: a cross-sectional study.

    abstract:OBJECTIVE:Screening is a key strategy to address the rising burden of chronic kidney disease (CKD) in low-income and middle-income countries. However, there are few reports regarding the implementation of screening programmes in resource-limited settings. The objectives of this study are to (1) to share programmatic ex...

    journal_title:BMJ open

    pub_type: 杂志文章

    doi:10.1136/bmjopen-2017-019778

    authors: Flood D,Garcia P,Douglas K,Hawkins J,Rohloff P

    更新日期:2018-01-21 00:00:00

  • Communication skills training for the radiotherapy team to manage cancer patients' emotional concerns: a systematic review.

    abstract:OBJECTIVES:Many cancer patients experience high levels of anxiety and concern during radiotherapy, often with long-lasting effects on their well-being. This systematic review aims to describe and determine the effectiveness of communication skills training (CST) for the radiotherapy team (RT) to improve conversations i...

    journal_title:BMJ open

    pub_type: 杂志文章

    doi:10.1136/bmjopen-2018-025420

    authors: van Beusekom MM,Cameron J,Bedi C,Banks E,Humphris G

    更新日期:2019-04-20 00:00:00

  • Pattern and spectrum of tornado injury and its geographical information system distribution in Yancheng, China: a cross-sectional study.

    abstract:OBJECTIVES:Few studies of tornado injuries have considered differences related to damage levels and Enhanced-Fujita (EF) scale ratings. This study aimed to evaluate the pattern, spectrum and geographical distribution of injuries related to the Yancheng tornado and provide guidelines for effective emergency medical stra...

    journal_title:BMJ open

    pub_type: 杂志文章,多中心研究

    doi:10.1136/bmjopen-2018-021552

    authors: Deng Q,Lv Y,Xue C,Kang P,Dong J,Zhang L

    更新日期:2018-06-22 00:00:00

  • Risk factors and determinants of carotid intima-media thickness in children: protocol for a systematic review and meta-analysis.

    abstract:INTRODUCTION:Carotid intima-media thickness (CIMT) is a surrogate marker of atherosclerosis that is measured in adults and children to better understand the natural history of cardiovascular disease (CVD). In adults, CIMT is predictive of myocardial infarction and stroke. In children and adolescents, CIMT is used to as...

    journal_title:BMJ open

    pub_type: 杂志文章

    doi:10.1136/bmjopen-2017-019644

    authors: Epure AM,Leyvraz M,Mivelaz Y,Di Bernardo S,da Costa BR,Chiolero A,Sekarski N

    更新日期:2018-06-04 00:00:00

  • Using telemedicine to support care for people with type 2 diabetes mellitus: a qualitative analysis of patients' perspectives.

    abstract:OBJECTIVE:Telemedicine has been promoted as an economical and effective way to enhance patient care, but its acceptance among patients in low-income and middle-income countries is poorly understood. This study is aimed to explore the experiences and perspectives of people with type 2 diabetes mellitus that used telemed...

    journal_title:BMJ open

    pub_type: 杂志文章

    doi:10.1136/bmjopen-2018-026575

    authors: Lee JY,Chan CKY,Chua SS,Paraidathathu T,Lee KK,Tan CSS,Nasir N,Lee SWH

    更新日期:2019-10-22 00:00:00

  • Rates of obstetric intervention among low-risk women giving birth in private and public hospitals in NSW: a population-based descriptive study.

    abstract:OBJECTIVES:To compare the risk profile of women giving birth in private and public hospitals and the rate of obstetric intervention during birth compared with previous published rates from a decade ago. DESIGN:Population-based descriptive study. SETTING:New South Wales, Australia. PARTICIPANTS:691 738 women giving b...

    journal_title:BMJ open

    pub_type: 杂志文章

    doi:10.1136/bmjopen-2012-001723

    authors: Dahlen HG,Tracy S,Tracy M,Bisits A,Brown C,Thornton C

    更新日期:2012-09-10 00:00:00

  • Effectiveness of peer educators on the uptake of mobile X-ray tuberculosis screening at homeless hostels: a cluster randomised controlled trial.

    abstract:TRIAL DESIGN:Cluster randomised controlled trial. OBJECTIVE:To compare current practice for encouraging homeless people to be screened for tuberculosis on a mobile digital X-ray unit in London, UK, with the additional use of volunteer peer educators who have direct experience of tuberculosis, homelessness or both. PA...

    journal_title:BMJ open

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1136/bmjopen-2015-008050

    authors: Aldridge RW,Hayward AC,Hemming S,Possas L,Ferenando G,Garber E,Lipman M,McHugh TD,Story A

    更新日期:2015-09-21 00:00:00

  • The AIDS epidemic and economic input impact factors in Chongqing, China, from 2006 to 2012: a spatial-temporal analysis.

    abstract:OBJECTIVE:To analyse the spatial-temporal clustering of the HIV/AIDS epidemic in Chongqing and to explore its association with the economic indices of AIDS prevention and treatment. METHODS:Data on the HIV/AIDS epidemic and economic indices of AIDS prevention and treatment were obtained from the annual reports of the ...

    journal_title:BMJ open

    pub_type: 杂志文章

    doi:10.1136/bmjopen-2014-006669

    authors: Zhang Y,Xiao Q,Zhou L,Ma D,Liu L,Lu R,Yi D,Yi D

    更新日期:2015-03-27 00:00:00

  • Quality of the diagnostic process in patients presenting with symptoms suggestive of bladder or kidney cancer: a systematic review.

    abstract:OBJECTIVES:In urological cancers, sex disparity exists for survival, with women doing worse than men. Suboptimal evaluation of presenting symptoms may contribute. DESIGN:We performed a systematic review examining factors affecting the quality of the diagnostic process of patients presenting with symptoms of bladder or...

    journal_title:BMJ open

    pub_type: 杂志文章

    doi:10.1136/bmjopen-2019-029143

    authors: Zhou Y,van Melle M,Singh H,Hamilton W,Lyratzopoulos G,Walter FM

    更新日期:2019-10-03 00:00:00

  • Berkson's bias in biobank sampling in a specialised mental health care setting: a comparative cross-sectional study.

    abstract:OBJECTIVES:To determine whether studying aetiological pathways of depression, in particular the well-established determinant of childhood trauma, only in a specialised mental healthcare setting can yield biased estimates of the aetiological association, given that the majority of individuals are treated in primary care...

    journal_title:BMJ open

    pub_type: 杂志文章

    doi:10.1136/bmjopen-2019-035088

    authors: Laliberté V,Giguère CE,Potvin S,Lesage A,Signature Consortium.

    更新日期:2020-07-23 00:00:00

  • Examining the relationship between neighbourhood deprivation and mental health service use of immigrants in Ontario, Canada: a cross-sectional study.

    abstract:OBJECTIVE:While newcomers are often disproportionately concentrated in disadvantaged areas, little attention is given to the effects of immigrants' postimmigration context on their mental health and care use. Intersectionality theory suggests that understanding the full impact of disadvantage requires considering the e...

    journal_title:BMJ open

    pub_type: 杂志文章

    doi:10.1136/bmjopen-2014-006690

    authors: Durbin A,Moineddin R,Lin E,Steele LS,Glazier RH

    更新日期:2015-03-13 00:00:00

  • Physical activity patterns in a representative sample of adolescents from the largest city in Latin America: a cross-sectional study in Sao Paulo.

    abstract:OBJECTIVES:We examined the patterns of total and domain-specific physical activity (PA) by sex, socioeconomic status and maternal education level in adolescents from Sao Paulo city, Brazil. DESIGN:Cross-sectional study. PARTICIPANTS:We included a representative sample of 2682 (52.2% boys) adolescents aged 14-15 years...

    journal_title:BMJ open

    pub_type: 杂志文章

    doi:10.1136/bmjopen-2020-037290

    authors: Ferrari G,Rezende LFM,Wagner GA,Florindo AA,Peres MFT

    更新日期:2020-09-02 00:00:00

  • Changing physical activity behaviour for people with multiple sclerosis: protocol of a randomised controlled feasibility trial (iStep-MS).

    abstract:INTRODUCTION:Although physical activity may reduce disease burden, fatigue and disability, and improve quality of life among people with multiple sclerosis (MS), many people with MS are physically inactive and spend significant time in sedentary behaviour. Behaviour change interventions may assist people with MS to inc...

    journal_title:BMJ open

    pub_type: 杂志文章,随机对照试验

    doi:10.1136/bmjopen-2017-018875

    authors: Ryan JM,Fortune J,Stennett A,Kilbride C,Anokye N,Victor C,Hendrie W,Abdul M,DeSouza L,Lavelle G,Brewin D,David L,Norris M

    更新日期:2017-11-15 00:00:00

  • Predicting risk of emergency admission to hospital using primary care data: derivation and validation of QAdmissions score.

    abstract:OBJECTIVE:To develop and externally validate a risk algorithm (QAdmissions) to estimate the risk of emergency hospital admission for patients aged 18-100 years in primary care. DESIGN:Prospective open cohort study using routinely collected data from general practice linked to hospital episode data during the 2-year st...

    journal_title:BMJ open

    pub_type: 杂志文章

    doi:10.1136/bmjopen-2013-003482

    authors: Hippisley-Cox J,Coupland C

    更新日期:2013-08-19 00:00:00

  • Establishing thresholds for important benefits considering the harms of screening interventions.

    abstract:CONTEXT AND OBJECTIVE:Standards for clinical practice guidelines require explicit statements regarding how values and preferences influence recommendations. However, no cancer screening guideline has addressed the key question of what magnitude of benefit people require to undergo screening, given its harms and burdens...

    journal_title:BMJ open

    pub_type: 杂志文章

    doi:10.1136/bmjopen-2020-037854

    authors: Helsingen LM,Zeng L,Siemieniuk RA,Lytvyn L,Vandvik PO,Agoritsas T,Bretthauer M,Guyatt G

    更新日期:2020-12-02 00:00:00

  • Evolution of pain at 3 months by oral resveratrol in knee osteoarthritis (ARTHROL): protocol for a multicentre randomised double-blind placebo-controlled trial.

    abstract:INTRODUCTION:Osteoarthritis (OA) pathophysiology is driven in part by joint inflammation. Resveratrol has in vitro anti-inflammatory properties. We aim to assess the efficacy of oral resveratrol for knee pain at 3 months in people with knee OA. METHODS AND ANALYSIS:We will conduct a randomised double-blind placebo-con...

    journal_title:BMJ open

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1136/bmjopen-2017-017652

    authors: Nguyen C,Boutron I,Baron G,Coudeyre E,Berenbaum F,Poiraudeau S,Rannou F

    更新日期:2017-09-29 00:00:00

  • Media Coverage of the Benefits and Harms of Testing the Healthy: a protocol for a descriptive study.

    abstract:INTRODUCTION:Much testing in medicine is aimed at healthy people to facilitate the early detection of health conditions. However, there is growing evidence that early detection is a double-edged sword that may cause harm in the form of overdiagnosis. The media can be seen as a major generator of consumer demand for hea...

    journal_title:BMJ open

    pub_type: 杂志文章

    doi:10.1136/bmjopen-2019-029532

    authors: O'Keeffe M,Barratt A,Maher C,Zadro J,Fabbri A,Jones M,Moynihan R

    更新日期:2019-08-24 00:00:00

  • Sexual minority population density and incidence of lung, colorectal and female breast cancer in California.

    abstract:OBJECTIVE:Risk factors for breast, colorectal, and lung cancer are known to be more common among lesbian, gay, and bisexual (LGB) individuals, suggesting they may be more likely to develop these cancers. Our objective was to determine differences in cancer incidence by sexual orientation, using sexual orientation data ...

    journal_title:BMJ open

    pub_type: 杂志文章

    doi:10.1136/bmjopen-2013-004461

    authors: Boehmer U,Miao X,Maxwell NI,Ozonoff A

    更新日期:2014-03-26 00:00:00

  • Outcomes following early parenteral nutrition use in preterm neonates: protocol for an observational study.

    abstract:INTRODUCTION:Preterm babies are among the highest users of parenteral nutrition (PN) of any patient group, but there is wide variation in commencement, duration, and composition of PN and uncertainty around which groups will benefit from early introduction. Recent studies in critically unwell adults and children sugges...

    journal_title:BMJ open

    pub_type: 杂志文章

    doi:10.1136/bmjopen-2019-029065

    authors: Webbe J,Longford N,Uthaya S,Modi N,Gale C

    更新日期:2019-07-09 00:00:00

  • Reducing distress and improving social functioning in daily life in people with auditory verbal hallucinations: study protocol for the 'Temstem' randomised controlled trial.

    abstract:INTRODUCTION:Auditory verbal hallucinations (AVH) are prevalent experiences that can induce distress and impede social functioning. While most voice hearers benefit from antipsychotic medication or cognitive-behavioural therapy, additional effective interventions are needed to reduce the burden of experiencing AVH. 'Te...

    journal_title:BMJ open

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1136/bmjopen-2017-020537

    authors: Jongeneel A,Scheffers D,Tromp N,Nuij C,Delespaul P,Riper H,van der Gaag M,van den Berg D

    更新日期:2018-03-06 00:00:00

  • Inhaler technique education in elderly patients with asthma or COPD: impact on disease exacerbations-a protocol for a single-blinded randomised controlled trial.

    abstract:INTRODUCTION:Chronic Obstructive Pulmonary Disease (COPD)and asthma affect more than 10% of the population. Most patients use their inhaler incorrectly, mainly the elderly, thereby becoming more susceptible to poor clinical control and exacerbations. Placebo device training is regarded as one of the best teaching metho...

    journal_title:BMJ open

    pub_type: 杂志文章

    doi:10.1136/bmjopen-2018-022685

    authors: Maricoto T,Correia-de-Sousa J,Taborda-Barata L

    更新日期:2019-01-28 00:00:00

  • Measuring 21 low-value hospital procedures: claims analysis of Australian private health insurance data (2010-2014).

    abstract:OBJECTIVE:To examine the prevalence, costs and trends (2010-2014) for 21 low-value inpatient procedures in a privately insured Australian patient cohort. DESIGN:We developed indicators for 21 low-value procedures from evidence-based lists such as Choosing Wisely, and applied them to a claims data set of hospital admis...

    journal_title:BMJ open

    pub_type: 杂志文章

    doi:10.1136/bmjopen-2018-024142

    authors: Chalmers K,Pearson SA,Badgery-Parker T,Brett J,Scott IA,Elshaug AG

    更新日期:2019-03-05 00:00:00

  • Impact of a mass media campaign on participation rates in a National Bowel Cancer Screening Program: a field experiment.

    abstract:OBJECTIVES AND DESIGN:This field experiment aimed to compare bowel cancer screening participation rates prior to, during and after a mass media campaign promoting screening, and the extent to which a higher intensity campaign in one state led to higher screening rates compared with another state that received lower int...

    journal_title:BMJ open

    pub_type: 杂志文章

    doi:10.1136/bmjopen-2018-024267

    authors: Durkin SJ,Broun K,Spittal MJ,Wakefield MA

    更新日期:2019-01-25 00:00:00

  • Direct costs of osteoporosis-related hip fractures: protocol for a cross-sectional analysis of a national database.

    abstract:INTRODUCTION:It is estimated that Iran accounted for about 1% of hip fracture burden of the world in 2007, but these data are based on incomplete evidence. As the country's population is ageing, it is expected that a dramatic rise in hip fracture incidence will result. There is no single national study that accurately ...

    journal_title:BMJ open

    pub_type: 杂志文章

    doi:10.1136/bmjopen-2016-014898

    authors: Maghbooli Z,Hossein-Nezhad A,Jafarpour M,Noursaadat S,Ramezani M,Hashemian R,Moattari S

    更新日期:2017-04-11 00:00:00

  • Multicentre, non-interventional study of the efficacy and tolerability of linaclotide in the treatment of irritable bowel syndrome with constipation in primary, secondary and tertiary centres: the Alpine study.

    abstract:OBJECTIVES:We evaluated the effectiveness and tolerability of linaclotide, a minimally absorbed guanylate cyclase-C agonist, in patients with irritable bowel syndrome with constipation (IBS-C) in routine clinical practice. SETTING:A multicentre, non-interventional study conducted between December 2013 and November 201...

    journal_title:BMJ open

    pub_type: 杂志文章,多中心研究

    doi:10.1136/bmjopen-2018-025627

    authors: Pohl D,Fried M,Lawrance D,Beck E,Hammer HF

    更新日期:2019-12-30 00:00:00

  • Patient and public priorities for breast cancer research: a qualitative study in the UK.

    abstract:OBJECTIVE:Internationally recognised specialist breast cancer scientists, clinicians and healthcare professionals have published breast cancer research gaps that are informing research funding priorities in the UK and worldwide. We aimed to determine the breast cancer research priorities of the public to compare with t...

    journal_title:BMJ open

    pub_type: 杂志文章

    doi:10.1136/bmjopen-2019-036072

    authors: Boundouki G,Wilson R,Duxbury P,Henderson J,Ballance L,Wray J,Appanah V,Ibrahim I,Harvey J,Kirwan CC,Northwest Breast Research Collaborative.

    更新日期:2021-01-29 00:00:00