Abstract:
OBJECTIVE:Screening is a key strategy to address the rising burden of chronic kidney disease (CKD) in low-income and middle-income countries. However, there are few reports regarding the implementation of screening programmes in resource-limited settings. The objectives of this study are to (1) to share programmatic experiences implementing CKD screening in a rural, resource-limited setting and (2) to assess the burden of renal disease in a community-based diabetes programme in rural Guatemala. DESIGN:Cross-sectional assessment of glomerular filtration rate (GFR) and urine albumin. SETTING:Central Highlands of Guatemala. PARTICIPANTS:We enrolled 144 adults with type 2 diabetes in a community-based CKD screening activity carried out by the sponsoring institution. OUTCOME MEASURES:Prevalence of renal disease and risk of CKD progression using Kidney Disease: Improving Global Outcomes definitions and classifications. RESULTS:We found that 57% of the sample met GFR and/or albuminuria criteria suggestive of CKD. Over half of the sample had moderate or greater increased risk for CKD progression, including nearly 20% who were classified as high or very high risk. Hypertension was common in the sample (42%), and glycaemic control was suboptimal (mean haemoglobin A1c 9.4%±2.5% at programme enrolment and 8.6%±2.3% at time of CKD screening). CONCLUSIONS:The high burden of renal disease in our patient sample suggests an imperative to better understand the burden and risk factors of CKD in Guatemala. The implementation details we share reveal the tension between evidence-based CKD screening versus screening that can feasibly be delivered in resource-limited global settings.
journal_name
BMJ Openjournal_title
BMJ openauthors
Flood D,Garcia P,Douglas K,Hawkins J,Rohloff Pdoi
10.1136/bmjopen-2017-019778subject
Has Abstractpub_date
2018-01-21 00:00:00pages
e019778issue
1issn
2044-6055pii
bmjopen-2017-019778journal_volume
8pub_type
杂志文章相关文献
BMJ Open文献大全abstract::Objectives (1) To assess endorsement of trial registration in author instructions of urology-related journals and (2) to assess whether randomised controlled trials (RCTs) in the field of urology were effectively registered. Design Cross-sectional study of author instructions and published trials. Setting Journals p...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2011-000430
更新日期:2011-12-06 00:00:00
abstract:INTRODUCTION:Development of digital breast tomosynthesis (DBT) provides a technology that generates three-dimensional data sets, thus reducing the pitfalls of overlapping breast tissue. Observational studies suggest that the combination of two-dimensional (2D) digital mammography and DBT increases diagnostic accuracy. ...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2017-020475
更新日期:2018-05-14 00:00:00
abstract:INTRODUCTION:Desert dust is estimated to constitute about 35% of aerosol in the troposphere. Desertification, climatic variability and global warming all can contribute to increased dust formation. This study aims to examine possible health effects of desert dust exposure on pregnant women and their children. The purpo...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2014-004863
更新日期:2014-06-23 00:00:00
abstract:OBJECTIVES:To investigate the relationship between poststroke fatigue and depression and subsequent mortality in young ischaemic stroke patients in a population-based study. DESIGN:A prospective cohort study. SETTING:All surviving young ischaemic stroke patients living in Hordaland County. PARTICIPANTS:Young ischaem...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2012-002404
更新日期:2013-03-01 00:00:00
abstract:OBJECTIVES:To identify spatial disparities and demographic characteristics of short stature, we analysed the prevalence of short stature collected in a nationwide health survey. SETTINGS:Data were obtained from the 2014 Chinese National Survey on Students Constitution and Health (a cross-sectional study of China). Par...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2018-026634
更新日期:2019-07-16 00:00:00
abstract:OBJECTIVES:Literature on associations between female genital mutilation/cutting (FGM/C) and fistula points to a common belief that FGM/C predisposes women to developing fistula. This study explores this association using nationally representative survey data. DESIGN:A secondary statistical analysis of cross-sectional ...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2018-025355
更新日期:2019-07-29 00:00:00
abstract:OBJECTIVE:Most of the Chinese occupational population are becoming at risk of noise-induced hearing loss (NIHL). However, there is a limited number of literature reviews on occupational NIHL in China. This study aimed to analyse the prevalence and characteristics of occupational NIHL in the Chinese population using dat...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2020-039576
更新日期:2020-09-28 00:00:00
abstract:INTRODUCTION:Health interventions often target pregnant women and their unborn children. Interventions in rural India targeting pregnant women, however, often do not cover the critical early windows of susceptibility during the first trimester and parts of the second trimester. This pilot seeks to determine if targetin...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2020-044127
更新日期:2020-10-05 00:00:00
abstract:OBJECTIVES:To understand the challenges faced by patients with tuberculosis (TB) and factors that influence TB treatment adherence in Ukraine. DESIGN:Qualitative study. SETTING:TB treatment facilities in Kyiv Oblast, Ukraine. PARTICIPANTS:Sixty adults who had undergone treatment for drug-sensitive TB between June 20...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2019-032027
更新日期:2020-02-02 00:00:00
abstract:INTRODUCTION:Carotid intima-media thickness (CIMT) is a surrogate marker of atherosclerosis that is measured in adults and children to better understand the natural history of cardiovascular disease (CVD). In adults, CIMT is predictive of myocardial infarction and stroke. In children and adolescents, CIMT is used to as...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2017-019644
更新日期:2018-06-04 00:00:00
abstract:INTRODUCTION:A significant proportion of the global burden of disease has been attributed to mental and behavioural disorders. People with mental disorders (MDs) have lower levels of health-related quality of life than those without MDs. Several studies have shown that in low-resource countries, a range of social deter...
journal_title:BMJ open
pub_type: 杂志文章,随机对照试验
doi:10.1136/bmjopen-2017-016745
更新日期:2017-09-01 00:00:00
abstract:OBJECTIVE:Recent studies have shown that people with mental illnesses have higher mortality and morbidity rates due to long-term conditions and lifestyle diseases. This knowledge has led to health promotion initiatives in mental health care to improve the physical health of people with mental illness. This article expl...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2019-036403
更新日期:2020-12-24 00:00:00
abstract:OBJECTIVE:To examine whether providing thermal clothing improved the health of patients with heart failure during winter. DESIGN:Parallel group randomised controlled trial. SETTING:Large public hospital in Brisbane during winter 2016. PARTICIPANTS:91 patients with systolic or diastolic heart failure who were over 50...
journal_title:BMJ open
pub_type: 杂志文章,随机对照试验
doi:10.1136/bmjopen-2017-017592
更新日期:2017-10-08 00:00:00
abstract:OBJECTIVE:To assess changes in incidence, diagnostic procedures, comorbidity profiles, length of hospital stay (LOHS), economic costs and in-hospital mortality (IHM) associated with idiopathic pulmonary fibrosis (IPF). METHODS:We identified patients hospitalised with IPF in Spain from 2004 to 2013. Data were collected...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2016-013156
更新日期:2017-02-13 00:00:00
abstract::The serial interval is the time between symptom onsets in an infector-infectee pair. The generation time, also known as the generation interval, is the time between infection events in an infector-infectee pair. The serial interval and the generation time are key parameters for assessing the dynamics of a disease. A n...
journal_title:BMJ open
pub_type: 杂志文章,评审
doi:10.1136/bmjopen-2020-040263
更新日期:2020-11-23 00:00:00
abstract:OBJECTIVE:To develop and externally validate a risk algorithm (QAdmissions) to estimate the risk of emergency hospital admission for patients aged 18-100 years in primary care. DESIGN:Prospective open cohort study using routinely collected data from general practice linked to hospital episode data during the 2-year st...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2013-003482
更新日期:2013-08-19 00:00:00
abstract:OBJECTIVES:Physically demanding work increases the risk of developing musculoskeletal disorders during working life, with low back pain (LBP) as the most prevalent and debilitating musculoskeletal disorder worldwide. However, a lack of knowledge exists about the role of early working years on musculoskeletal health lat...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2020-040158
更新日期:2020-12-07 00:00:00
abstract:OBJECTIVES:To report the distribution and predictors of insulin resistance (IR) in young people presenting to primary care-based mental health services. DESIGN:Cross-sectional. SETTING:Headspace-linked clinics operated by the Brain and Mind Centre of the University of Sydney. PARTICIPANTS:768 young people (66% femal...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2018-025674
更新日期:2019-05-27 00:00:00
abstract:OBJECTIVES:To develop an optimised 1:1 physiotherapy intervention that reflects best practice, with flexibility to tailor management to individual patients, thereby ensuring patient-centred practice. DESIGN:Mixed-methods combining evidence synthesis, expert review and focus groups. SETTING:Secondary care involving 5 ...
journal_title:BMJ open
pub_type: 杂志文章,多中心研究
doi:10.1136/bmjopen-2015-009409
更新日期:2016-02-25 00:00:00
abstract:INTRODUCTION:Labour induction in women with a previous caesarean delivery currently uses vaginal prostaglandin E2 (PGE2), which carries the risks of uterine hyperstimulation and scar rupture. We aim to compare the efficacy of mechanical labour induction using a transcervically applied Foley catheter balloon (FCB) with ...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2019-028896
更新日期:2019-11-06 00:00:00
abstract:INTRODUCTION:Diabetic macular oedema (DMO) and proliferative diabetic retinopathy (PDR) are the major causes of sight loss in people with diabetes. Due to the increased prevalence of diabetes, the workload related to these complications is increasing making it difficult for Hospital Eye Services (HSE) to meet demands. ...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2018-027795
更新日期:2019-06-28 00:00:00
abstract:OBJECTIVES:To explore the prevalence, discomfort, and self-relief behaviours of painful diabetic neuropathy (PDN) among rural community residents with type 2 diabetes. DESIGN:A community-based, cross-sectional study. SETTING:This study was part of a longitudinal cohort study of a nurse-led health promotion programme ...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2016-011897
更新日期:2016-10-03 00:00:00
abstract:INTRODUCTION:Depression is a common mental disorder in the elderly population, which significantly impacts their quality of life. However, correct estimates of its magnitude are not available in the elderly in India. The present systematic review and meta-analysis would attempt to estimate the prevalence of depression ...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2019-034330
更新日期:2020-05-07 00:00:00
abstract:OBJECTIVE:To establish the reliability and validity of the translated version of the Safety Attitudes Questionnaire (SAQ) by evaluating its psychometric properties and to determine possible differences among nurses and physicians regarding safety attitudes. DESIGN:A cross-sectional study utilising the Albanian version...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2014-006528
更新日期:2015-04-15 00:00:00
abstract:INTRODUCTION:High body mass index (BMI) is associated with risk of diabetes. Lorcaserin is a selective 5-hydroxytryptamine 2C agonist which exerts robust benefits on long-term weight loss by suppressing appetite among adults with overweight or obesity. The magnitude of efficacy of lorcaserin for preventing and remittin...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2019-029426
更新日期:2019-07-27 00:00:00
abstract:OBJECTIVES:To explore participants' views of Delphi surveys in core outcome set (COS) development. STUDY DESIGN AND SETTING:Patients and health professionals (n=24) from seven recently concluded COS studies that had involved a Delphi survey took part in semistructured qualitative interviews (telephone and email exchan...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2019-032338
更新日期:2019-11-14 00:00:00
abstract:INTRODUCTION:Venoarterial extracorporeal membrane oxygenation (VA-ECMO) is widely used to support the most severe forms of cardiogenic shock (CS). Nevertheless, despite extracorporeal membrane oxygenation (ECMO) use, mortality still remains high (50%). Moderate hypothermia (MH) (33°C-34°C) may improve cardiac performan...
journal_title:BMJ open
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1136/bmjopen-2019-031697
更新日期:2019-10-14 00:00:00
abstract:OBJECTIVE:This study explores the relationship between health access barriers and diabetes in an urban First Nations population in Canada. DESIGN:Data from a self-identified urban First Nations population were collected using respondent-driven sampling (RDS). As no clear approach for regression modelling of RDS data i...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2017-018272
更新日期:2018-01-21 00:00:00
abstract:OBJECTIVES:To identify the use and adverse drug reactions associated with azithromycin in neonates. SETTING:Databases MEDLINE (1948-August 2015), EMBASE (1980-August 2015) and Pubmed (August 2015) were searched for studies on azithromycin in neonates. PARTICIPANTS:All studies involving neonates (<28 days old) who hav...
journal_title:BMJ open
pub_type: 杂志文章,评审
doi:10.1136/bmjopen-2015-008194
更新日期:2015-12-09 00:00:00
abstract:OBJECTIVES:To estimate the prevalence of poor vision in children aged 4-5 years and determine the impact of visual acuity on literacy. DESIGN:Cross-sectional study linking clinical, epidemiological and education data. SETTING:Schools located in the city of Bradford, UK. PARTICIPANTS:Prevalence was determined for 11,...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2015-010434
更新日期:2016-02-16 00:00:00