Abstract:
OBJECTIVES:To investigate the relationship between poststroke fatigue and depression and subsequent mortality in young ischaemic stroke patients in a population-based study. DESIGN:A prospective cohort study. SETTING:All surviving young ischaemic stroke patients living in Hordaland County. PARTICIPANTS:Young ischaemic stroke patients aged 15-50 years at the time of the stroke were invited to a follow-up on an average 6 years after the index stroke. Psychosocial factors and risk factors were registered. Fatigue was self-assessed by the Fatigue Severity Scale (FSS). Depression was measured by Montgomery-Åsberg Depression Rating Scale (MADRS). INTERVENTION:No intervention was performed. PRIMARY AND SECONDARY OUTCOME MEASURE:Mortality on follow-up. RESULTS:In total, 190 patients were included. The mean age on follow-up was 48 years and subsequent follow-up period was 12 years. Cox regression analysis showed that mortality was associated with FSS score (p=0.005) after adjusting for age (p=0.06) and sex (p=0.19). Cox regression analysis showed that mortality was associated with MADRS score (p=0.006) after adjusting for age (p=0.10) and sex (p=0.11). CONCLUSIONS:Both fatigue and depression are associated with long-term mortality in young adults with ischaemic stroke. Depression may be linked to higher mortality because of psychosocial factors and unhealthy lifestyles whereas the link between fatigue and mortality is broader including connection to diabetes mellitus, myocardial infarction and psychosocial factors.
journal_name
BMJ Openjournal_title
BMJ openauthors
Naess H,Nyland Hdoi
10.1136/bmjopen-2012-002404subject
Has Abstractpub_date
2013-03-01 00:00:00issue
3issn
2044-6055pii
bmjopen-2012-002404journal_volume
3pub_type
杂志文章相关文献
BMJ Open文献大全abstract:OBJECTIVES:The aim was to examine health-related quality of life (HRQoL), patient characteristics and reasons for visits to general practitioners (GPs) by frequent attenders (FAs) and a comparison group (CG) in primary care. METHODS:Patients aged 18-64 years were eligible for the study. Medical records were scrutinise...
journal_title:BMJ open
pub_type: 杂志文章,多中心研究
doi:10.1136/bmjopen-2018-026855
更新日期:2019-07-30 00:00:00
abstract:OBJECTIVE:To clarify the pathophysiological basis of persistent geotropic positional nystagmus (PGN) in patients with the horizontal canal type of benign paroxysmal positional vertigo (H-BPPV), the time constant (TC) of nystagmus and the relationship between its slow phase eye velocity (SPV) and the angle of head rotat...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2014-006607
更新日期:2015-01-13 00:00:00
abstract:OBJECTIVES:To determine whether there was variation in nurse staffing across hospitals in Queensland prior to implementation of nurse-to-patient ratio legislation targeting medical-surgical wards, and if so, the extent to which nurse staffing variation was associated with poor outcomes for patients and nurses. DESIGN:...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2019-036264
更新日期:2020-09-06 00:00:00
abstract:OBJECTIVE:To determine the feasibility of a randomised controlled trial (RCT) assessing the effects of an experience-based website as a resource for the self-management of chronic asthma. DESIGN AND SETTING:Feasibility, single-blind RCT in 2 regions of England. Randomisation used computer-generated random number seque...
journal_title:BMJ open
pub_type: 杂志文章,随机对照试验
doi:10.1136/bmjopen-2016-013401
更新日期:2016-12-28 00:00:00
abstract:PURPOSE:Chagas disease (CD) has become a global health issue mainly due to migration. Germany lacks surveillance data and is home to a large Latin American immigrant population. Recognising that Bolivia is the country with the highest CD prevalence in Latin America, this cross-sectional, descriptive pilot study investi...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2016-013960
更新日期:2017-01-16 00:00:00
abstract:INTRODUCTION:Families in low-income and middle-income countries (LMICs) face multiple challenges (eg, poverty and adverse childhood experiences) that increase the risk for child mental health problems, while the context may provide them with few resources. Existing prevention-oriented parenting programmes have been sho...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2018-026684
更新日期:2019-01-25 00:00:00
abstract:OBJECTIVES:Development of medical test guidelines differs from intervention guideline development. These differences can pose unique challenges in building evidence-based recommendations to guide clinical practice. The aim of our study was to better understand these challenges, explore reasons behind them and identify ...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2015-010549
更新日期:2016-09-16 00:00:00
abstract:OBJECTIVES:To describe the role patient expectations play in general practitioners (GPs) antibiotic prescribing for upper respiratory tract infections (URTI). METHODS:Concurrent explanatory mixed methods approach using a cross-sectional survey and semistructured interviews. SETTINGS:Primary care GPs in Australia. PA...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2016-012244
更新日期:2016-10-24 00:00:00
abstract:INTRODUCTION:Lumbar discectomy is a widely used surgical procedure internationally with the majority of patients experiencing significant benefit. However, approximately 20% of patients report suboptimal functional recovery and quality of life. The impact and meaning of the surgical experience from the patients' perspe...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2018-025814
更新日期:2019-08-15 00:00:00
abstract:OBJECTIVE:New electronic devices offer an opportunity within routine primary care settings for improving the detection of atrial fibrillation (AF), which is a common cardiac arrhythmia and a modifiable risk factor for stroke. We aimed to assess the performance of a modified blood pressure (BP) monitor and two single-le...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2013-004565
更新日期:2014-05-02 00:00:00
abstract:OBJECTIVES:The Acne Priority Setting Partnership (PSP) was set up to identify and rank treatment uncertainties by bringing together people with acne, and professionals providing care within and beyond the National Health Service (NHS). SETTING:The UK with international participation. PARTICIPANTS:Teenagers and adults...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2015-008085
更新日期:2015-07-17 00:00:00
abstract:OBJECTIVE:Internationally recognised specialist breast cancer scientists, clinicians and healthcare professionals have published breast cancer research gaps that are informing research funding priorities in the UK and worldwide. We aimed to determine the breast cancer research priorities of the public to compare with t...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2019-036072
更新日期:2021-01-29 00:00:00
abstract:BACKGROUND:Research on patient safety in emergency medical services (EMS) has mainly focused on the organisation's and/or the EMS personnel's perspective. Little is known about how patients perceive safety in EMS. This study aims to describe the patients' experiences of their sense of safety in EMS. METHODS:A qualitat...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2020-037488
更新日期:2020-10-21 00:00:00
abstract:INTRODUCTION:In patients with large abdominal aortic aneurysm (AAA), open surgical or endovascular aneurysm repair procedures are often used to minimise the risk of aneurysm-related rupture and death; however, aneurysm repair itself carries a high risk. Low cardiopulmonary fitness is associated with an increased risk o...
journal_title:BMJ open
pub_type: 杂志文章,随机对照试验
doi:10.1136/bmjopen-2013-004094
更新日期:2014-01-10 00:00:00
abstract:OBJECTIVES:To investigate the association between the difficulty in hospital acceptance at the scene by emergency medical service (EMS) personnel and prehospital demographic factors and reasons for EMS calls. DESIGN:A retrospective, observational study. SETTING:Osaka City, Japan. PARTICIPANTS:A total of 100 649 pati...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2016-013849
更新日期:2016-10-26 00:00:00
abstract:INTRODUCTION:The Australian Council on Healthcare Standards (ACHS) set criteria for the delivery of healthcare services in Australia. While a voluntary process, continual accreditation with ACHS is an expectation of, and for, Australian healthcare providers. Juxtapositioned with the ACHS, the Nursing and Midwifery Boar...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2019-031499
更新日期:2019-08-24 00:00:00
abstract:INTRODUCTION:Venoarterial extracorporeal membrane oxygenation (VA-ECMO) is widely used to support the most severe forms of cardiogenic shock (CS). Nevertheless, despite extracorporeal membrane oxygenation (ECMO) use, mortality still remains high (50%). Moderate hypothermia (MH) (33°C-34°C) may improve cardiac performan...
journal_title:BMJ open
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1136/bmjopen-2019-031697
更新日期:2019-10-14 00:00:00
abstract:INTRODUCTION:Two-wheel bike riding can be a goal for children with cerebral palsy (CP) and a means of participating in physical activity. It is possible for some children with CP to ride a two-wheel bike; however, currently far fewer can ride compared with their typically developing peers. Evidence supports training ta...
journal_title:BMJ open
pub_type: 杂志文章,随机对照试验
doi:10.1136/bmjopen-2017-019898
更新日期:2018-02-03 00:00:00
abstract:OBJECTIVES:To investigate different professionals' (nurse anaesthetists', anaesthesiologists', and postanaesthesia care unit nurses') descriptions of and reflections on the postoperative handover. DESIGN:A focus group interview study with a descriptive design using qualitative content analysis of transcripts. SETTING...
journal_title:BMJ open
pub_type: 杂志文章,多中心研究
doi:10.1136/bmjopen-2016-015038
更新日期:2017-08-04 00:00:00
abstract:INTRODUCTION:Diagnosis of endoleaks is imperative to prevent failure of endovascular aneurysm repairs (EVARs). The gold standard for diagnosis of endoleaks is catheter-directed subtraction angiography, which is not a practicable choice for surveillance. CT angiography (CTA) is the historical surveillance modality of ch...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2017-020835
更新日期:2018-04-03 00:00:00
abstract:INTRODUCTION:Osteoarthritis (OA) pain is a major cause of long-term disability and chronic pain in the adult population. One in five patients does not receive satisfactory pain relief, which reflects the complexity of chronic pain and the current lack of understanding of mechanisms of chronic pain. Recently, duloxetine...
journal_title:BMJ open
pub_type: 杂志文章,随机对照试验
doi:10.1136/bmjopen-2016-014013
更新日期:2017-06-26 00:00:00
abstract:INTRODUCTION:There is a renewed global interest in improving community health worker (CHW) programmes. For CHW programmes to be effective, key intervention design factors which contribute to the performance of CHWs need to be identified. The recent WHO guidelines recommends the combination of financial and non-financia...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2019-033601
更新日期:2019-12-11 00:00:00
abstract:STUDY OBJECTIVE:To evaluate the implementation of the Ohio Emergency and Acute Care Facility Opioids and Other Controlled Substances Prescribing Guidelines and their perceived impact on local policies and practice. METHODS:The study design was a cross-sectional survey of emergency department (ED) medical directors, or...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2017-020477
更新日期:2018-06-30 00:00:00
abstract:INTRODUCTION:The acceptability and efficacy of existing ready-to-use supplementary and therapeutic foods has been low in Cambodia, thus limiting success in preventing and treating malnutrition among Cambodian children. In that context, UNICEF and IRD have developed a locally produced, multiple micronutrient fortified l...
journal_title:BMJ open
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1136/bmjopen-2017-015958
更新日期:2017-09-06 00:00:00
abstract:OBJECTIVE:To appraise and synthesise research on the impact of physician assistants/associates (PA) in secondary care, specifically acute internal medicine, care of the elderly, emergency medicine, trauma and orthopaedics, and mental health. DESIGN:Systematic review. SETTING:Electronic databases (Medline, Embase, ASS...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2017-019573
更新日期:2018-06-19 00:00:00
abstract:OBJECTIVE:We aimed to determine the key predictors of perinatal deaths using machine learning models compared with the logistic regression model. DESIGN:A secondary data analysis using the Kilimanjaro Christian Medical Centre (KCMC) Medical Birth Registry cohort from 2000 to 2015. We assessed the discriminative abilit...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2020-040132
更新日期:2020-10-19 00:00:00
abstract:OBJECTIVE:A timely initiation of treatment is crucial to better control tuberculosis (TB). The aim of this study is to describe treatment delay among migrant patients with TB and to identify factors associated with treatment delay, so as to provide evidence for strategy development and improvement of TB control among m...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2014-005805
更新日期:2014-12-22 00:00:00
abstract:OBJECTIVE:To investigate the risk of cancer and potential gender effects in persons hospitalised with burn injury. DESIGN:Population-based retrospective cohort study using record-linkage systems in Scotland and Western Australia. PARTICIPANTS:Records of 37 890 and 23 450 persons admitted with a burn injury in Scotlan...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2013-003845
更新日期:2014-01-17 00:00:00
abstract:OBJECTIVE:To assess the sociodemographic patterning of changes in glycaemic control of patients with diabetes affected by the 2011 triple disaster in Japan (earthquake, tsunami and nuclear accident). METHODS:A retrospective cohort study was undertaken with 404 patients with diabetes at a public hospital in Minamisoma ...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2016-011455
更新日期:2016-07-07 00:00:00
abstract:OBJECTIVE:To develop and validate a prediction model for identifying women at increased risk of developing gestational hypertension (GH) in Ghana. DESIGN:A prospective study. We used frequencies for descriptive analysis, χ2 test for associations and logistic regression to derive the prediction model. Discrimination wa...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2016-012670
更新日期:2017-01-16 00:00:00