Abstract:
INTRODUCTION:Two-wheel bike riding can be a goal for children with cerebral palsy (CP) and a means of participating in physical activity. It is possible for some children with CP to ride a two-wheel bike; however, currently far fewer can ride compared with their typically developing peers. Evidence supports training targeted towards goals of the child with CP and their family; yet there is little evidence to guide best-practice bike skills training. Task-specific training may lead to attainment of two-wheel bike-specific goals. This study aims to determine if a novel task-specific approach to training two-wheel bike skills is more effective than a parent-led home programme for attaining individualised two-wheel bike-specific goals in independently ambulant children with CP aged 6-15 years. METHODS AND ANALYSIS:Sixty eligible children with CP (Gross Motor Function Classification System levels I-II) aged 6-15 years with goals relating to riding a two-wheel bike will be randomised to either a novel task-specific centre-based group programme (intervention) or a parent-led home-based programme (comparison), both involving a 1-week intervention period. The primary outcome is goal attainment in the week following the intervention period (T1). Secondary outcomes include: goal attainment and participation in physical activity at 3 months postintervention (T2) and bike skills, attendance and involvement in bike riding, self-perception and functional skills at T1 and T2. Economic appraisal will involve cost-effectiveness and cost-utility analyses. Adherence of clinicians and parents to the intervention and comparison protocols will be assessed. Linear and logistic regression will be used to assess the effect of the intervention, adjusted for site as used in the randomisation process. ETHICS AND DISSEMINATION:This study was approved by the Human Research and Ethics Committees at The Royal Children's Hospital (#36209). Results will be disseminated via peer-reviewed publications and conference presentations. TRIAL REGISTRATION NUMBER:NCT03003026; Pre-results.
journal_name
BMJ Openjournal_title
BMJ openauthors
Toovey R,Harvey AR,McGinley JL,Lee KJ,Shih STF,Spittle AJdoi
10.1136/bmjopen-2017-019898subject
Has Abstractpub_date
2018-02-03 00:00:00pages
e019898issue
2issn
2044-6055pii
bmjopen-2017-019898journal_volume
8pub_type
杂志文章,随机对照试验相关文献
BMJ Open文献大全abstract:INTRODUCTION:Rapid technology development due to the introduction of Industrial Revolution 4.0 and Internet of Things has created a demand and gradual transition from traditional teaching and learning to technology-based learning in higher education, including healthcare education. The COVID-19 pandemic has accelerated...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2020-041153
更新日期:2020-11-23 00:00:00
abstract:INTRODUCTION:Self-management and remaining physically active are first-line recommendations for the care of patients with low back pain (LBP). With a lifetime prevalence of up to 85%, novel approaches to support behavioural self-management are needed. Internet interventions may provide accessible support for self-manag...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2020-040543
更新日期:2020-08-20 00:00:00
abstract:OBJECTIVES:In recent years, the involvement of pharmacy technicians in medication reconciliation has increasingly been investigated. The aim of this study was to assess the implications on professional roles and collaboration when a best possible medication history (BPMH) at admission is obtained by pharmacy technician...
journal_title:BMJ open
pub_type: 杂志文章,多中心研究
doi:10.1136/bmjopen-2017-020566
更新日期:2018-05-17 00:00:00
abstract:OBJECTIVES:To identify scenarios based on socioeconomic, epidemiological and operational healthcare factors associated with tuberculosis incidence in Brazil. DESIGN:Ecological study. SETTINGS:The study was based on new patients with tuberculosis and epidemiological/operational variables of the disease from the Brazil...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2017-018545
更新日期:2018-06-06 00:00:00
abstract:OBJECTIVE:This study aimed to evaluate the factor structure of the Chinese version of the 22-item Zarit Burden Interview (ZBI) among family caregivers of patients with schizophrenia in China. METHODS:Using one-stage cluster-sampling design, 324 primary caregivers of patients with schizophrenia in Ningxiang County, Hun...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2016-015621
更新日期:2017-09-29 00:00:00
abstract:OBJECTIVES:To assess compliance with 2010 National Institute for Health and Care Excellence (NICE) guidance on cancer services relating to the management of basal cell carcinomas (BCC) in the community, where except in specific circumstances it is recommended that only low-risk BCCs should be excised routinely. DESIGN...
journal_title:BMJ open
pub_type: 杂志文章,多中心研究
doi:10.1136/bmjopen-2018-023299
更新日期:2019-02-22 00:00:00
abstract:OBJECTIVE:We implemented this study to report the prevalence and associated risk factors of hypertension among adult men and women aged >30 years residing in selected urban and rural areas of Dhaka division, Bangladesh. DESIGN:Cross-sectional study. SETTING:Two urban (Dhaka city north and Dhaka city south) and two ru...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2020-038975
更新日期:2021-01-20 00:00:00
abstract:INTRODUCTION:Internet-based and mobile-based interventions (IMIs) provide an innovative and efficient self-management tool for mental health problems. This systematic review aims to summarise and critically evaluate studies addressing the effectiveness and feasibility of IMIs for normal and complicated grief in bereave...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2019-036034
更新日期:2020-04-22 00:00:00
abstract:INTRODUCTION:Harm from catheter-associated urinary tract infections is a common, potentially avoidable, healthcare complication. Variation in catheter prevalence may exist and provide opportunity for reducing harm, yet to date is poorly understood. This study aimed to determine variation in the prevalence of urinary ca...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2016-013842
更新日期:2017-06-23 00:00:00
abstract:PURPOSE:Optical coherence tomography (OCT) captures retinal damage in neuromyelitis optica spectrum disorders (NMOSD). Previous studies investigating OCT in NMOSD have been limited by the rareness and heterogeneity of the disease. The goal of this study was to establish an image repository platform, which will facilita...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2019-035397
更新日期:2020-10-29 00:00:00
abstract:OBJECTIVE:Neisseria meningitidis carriage prevalence has known variation across the lifespan, but it is unclear whether carriage varies among meningococcal capsular groups. Therefore, we aimed to characterise group-specific meningococcal carriage by age group and world region from 2007 to 2016. DESIGN:Systematic revie...
journal_title:BMJ open
pub_type: 杂志文章,meta分析
doi:10.1136/bmjopen-2018-024343
更新日期:2019-04-20 00:00:00
abstract:OBJECTIVES:Development of medical test guidelines differs from intervention guideline development. These differences can pose unique challenges in building evidence-based recommendations to guide clinical practice. The aim of our study was to better understand these challenges, explore reasons behind them and identify ...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2015-010549
更新日期:2016-09-16 00:00:00
abstract:OBJECTIVES:The rate of falling among older citizens appears to vary across different countries, but the underlying aspects causing this variation are unexplained. We aim to describe between-country variation in falling and explore whether intrinsic fall risk factors can explain possible variation. DESIGN:Prospective s...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2017-015827
更新日期:2017-06-30 00:00:00
abstract:OBJECTIVES:Malignant melanoma has high morbidity and mortality rates. Early diagnosis improves prognosis. Clinical prediction rules (CPRs) can be used to stratify patients with symptoms of suspected malignant melanoma to improve early diagnosis. We conducted a systematic review of CPRs for melanoma diagnosis in ambulat...
journal_title:BMJ open
pub_type: 杂志文章,评审
doi:10.1136/bmjopen-2016-014096
更新日期:2017-03-06 00:00:00
abstract:INTRODUCTION:Cardiovascular disease (CVD) and cancer are leading causes of death globally. Early detection of cancer and risk factors for CVD may improve health outcomes and reduce mortality. General practitioners (GPs) are accessed by the majority of the population and play a key role in the prevention and early detec...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2012-001405
更新日期:2012-07-02 00:00:00
abstract:OBJECTIVE:To determine whether occupational exposure to silica dust causes an increased risk of developing Crohn's disease (CD) and ulcerative colitis (UC). DESIGN:Case-control study of CD (K50) and UC (K51) from 2007 through 2016. Controls were matched to cases (2:1) based on age, sex and county at the time of diagno...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2019-034752
更新日期:2020-02-16 00:00:00
abstract:OBJECTIVES:The aim of this study was to identify meteorological factors that could be associated with an increased risk of community-acquired Legionnaires' disease (LD) in two Swiss regions. DESIGN:Retrospective epidemiological study using discriminant analysis and multivariable Poisson regression. SETTING:We analyse...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2012-002428
更新日期:2013-03-05 00:00:00
abstract:OBJECTIVE:To assess the representativeness of the Heart Protection Study (HPS) and the Collaborative Atorvastatin Diabetes Study (CARDS) for incident statin users. DESIGN:A population-based analysis with linked register data. SETTING:Finland. POPULATION:56 963 patients with diabetes initiating statin use from 2005 t...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2014-005402
更新日期:2014-06-19 00:00:00
abstract:INTRODUCTION:Pulmonary embolism poses one of the most challenging diagnoses in medicine. Resolving these diagnostic difficulties is more crucial in emergency departments where fast and accurate decisions are needed for a life-saving purpose. Here, clinical pretest evaluation is an important step in the diagnostic algor...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2019-031322
更新日期:2019-10-15 00:00:00
abstract:INTRODUCTION:Fracture healing can fail in up to 10% of cases despite appropriate treatment. While lithium has been the standard treatment for bipolar disorder, it may also have a significant impact to increase bone healing in patients with long bone fractures. To translate this knowledge into clinical practice, a rando...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2019-031545
更新日期:2020-01-07 00:00:00
abstract:OBJECTIVES:Novel therapeutics are an important part of ophthalmologists' armamentarium, and the risks and benefits of these therapies must be carefully evaluated. We sought to quantify the characteristics of the pivotal clinical trials supporting the regulatory approval of new ophthalmic drugs and medical devices. DES...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2015-007987
更新日期:2015-06-04 00:00:00
abstract:INTRODUCTION:Mild obstructive sleep-disordered breathing (oSDB), characterised by habitual snoring without frequent apnoeas and hypopnoeas on polysomnography, is prevalent in children and commonly treated with adenotonsillectomy (AT). However, the absence of high-level evidence addressing the role of AT in improving he...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2019-033889
更新日期:2020-03-15 00:00:00
abstract:OBJECTIVES:To examine the extent of primary care follow-up and mental health outcomes among women referred for ultrasound assessment of pain and/or bleeding in early pregnancy, including those whose pregnancy is found to be viable on ultrasound assessment. DESIGN:Questionnaire study with prospective follow-up. SETTIN...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2013-002595
更新日期:2013-04-11 00:00:00
abstract:INTRODUCTION:Acute, non-low back-related musculoskeletal pain is common and associated with significant socioeconomic costs. No review has evaluated all interventional studies for acute musculoskeletal pain, which limits attempts to make inferences regarding the relative effectiveness of treatments. METHODS AND ANALYS...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2018-024441
更新日期:2019-04-03 00:00:00
abstract:OBJECTIVE:To explore clinicians' perspectives on supporting parents' decision-making following diagnosis of a severe congenital anomaly, and how this is shaped by current policy. METHODS:This paper reports data collated as part of a larger project examining parents' decision-making following antenatal diagnosis. The f...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2016-014716
更新日期:2017-06-06 00:00:00
abstract:INTRODUCTION:Type 2 diabetes (T2D) is a significant problem, and lifestyle modifications including self-management are important. We have developed a structured individual-based lifestyle education (SILE) programme for T2D. With attention now being paid to techniques to change behaviour, we recently developed a behavio...
journal_title:BMJ open
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1136/bmjopen-2017-017838
更新日期:2017-10-24 00:00:00
abstract:OBJECTIVES:To assess the impact of both the Committee on Safety of Medicines (CSM) warning (December 2003) and the National Institute for Health and Care Excellence (NICE) guidance (September 2005) on antidepressant prescription rates in children and adolescents within the UK primary care service. SETTING:Population b...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2018-028201
更新日期:2019-08-07 00:00:00
abstract:OBJECTIVES:To investigate mortality in adults with intellectual disabilities: rates, causes, place, demographic and clinical predictors. DESIGN:Cohort study with record linkage to death data. SETTING:General community. PARTICIPANTS:961/1023 (94%) adults (16-83 years; mean=44.1 years; 54.6% male) with intellectual di...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2019-036465
更新日期:2020-05-17 00:00:00
abstract:INTRODUCTION:Delirium is very common in patients admitted to intensive care unit (ICU), and may worsen survival in these patients. Several meta-analyses have evaluated the antidelirium effects of dexmedetomidine in ICU patients, but their findings were inconsistent. Recently, several large multicentre randomised clinic...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2018-025850
更新日期:2019-04-03 00:00:00
abstract::Objective To investigate the views and practices of UK medical schools regarding the inclusion (or exclusion) of complementary and alternative medicine (CAM) in undergraduate medical curricula. Design Survey (by email) of UK medical schools offering MBBS (or equivalent) degrees. Results The overall response rate was...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2011-000074
更新日期:2011-06-08 00:00:00