Effects of dexmedetomidine on delirium and mortality during sedation in ICU patients: a systematic review and meta-analysis protocol.

abstract：OBJECTIVE:To explore satisfaction of care received by older adult patients and their primary caregivers following traumatic injury. DESIGN:Prospective, cross-sectional study using the FAMCARE (Family Satisfaction with Advanced Cancer Care Scale) satisfaction surveys prior to discharge. SETTING:Three level I trauma ce...

journal_title：BMJ open

authors： Vogel R,McGraw C,Orlando A,Bourg P,Dreiman C,Peck L,Tanner A,Lynch N,Bar-Or D

更新日期：2019-11-11 00:00:00

abstract：INTRODUCTION:While tobacco smoking prevalence is falling in many western societies, it remains elevated among high-priority cohorts. Rates up to 95% have been reported in women whose pregnancy is complicated by other substance use. In this group, the potential for poor pregnancy outcomes and adverse physical and neurob...

journal_title：BMJ open

authors： Jackson MA,Brown AL,Baker AL,Gould GS,Dunlop AJ

更新日期：2019-11-21 00:00:00

abstract：OBJECTIVES:In urological cancers, sex disparity exists for survival, with women doing worse than men. Suboptimal evaluation of presenting symptoms may contribute. DESIGN:We performed a systematic review examining factors affecting the quality of the diagnostic process of patients presenting with symptoms of bladder or...

journal_title：BMJ open

authors： Zhou Y,van Melle M,Singh H,Hamilton W,Lyratzopoulos G,Walter FM

更新日期：2019-10-03 00:00:00

abstract：INTRODUCTION:Sarcoidosis is an incurable, chronic granulomatous disease primarily involving the lungs and lymph nodes of unknown aetiology, treated with non-specific anti-inflammatory/immunosuppressive drugs. Persistently symptomatic patients worsen with a disabling, potentially fatal clinical course. To determine a po...

journal_title：BMJ open

authors： Robinson LA,Smith P,Sengupta DJ,Prentice JL,Sandin RL

更新日期：2013-12-23 00:00:00

abstract：OBJECTIVES:Current strategies to prevent adult pneumococcal disease have been recently reviewed in Italy. We did a postlicensure study to estimate the direct vaccine effectiveness (VE) of the 13-valent pneumococcal conjugate vaccine (PCV13) against adult pneumococcal community-acquired pneumonia (pCAP). STUDY DESIGN:B...

journal_title：BMJ open

authors： Prato R,Fortunato F,Cappelli MG,Chironna M,Martinelli D

更新日期：2018-03-25 00:00:00

abstract：INTRODUCTION:In rapidly developing countries such as India, the ubiquity of air pollution sources in urban and rural communities often results in ambient and household exposures significantly in excess of health-based air quality guidelines. Few efforts, however, have been directed at establishing quantitative exposure...

journal_title：BMJ open

authors： Balakrishnan K,Sambandam S,Ramaswamy P,Ghosh S,Venkatesan V,Thangavel G,Mukhopadhyay K,Johnson P,Paul S,Puttaswamy N,Dhaliwal RS,Shukla DK,SRU-CAR Team.

更新日期：2015-06-10 00:00:00

abstract：INTRODUCTION:Up to 1 in 4 pregnancies and 1 in 20 subsequent pregnancies end in miscarriage. Despite such prevalence the psychosocial effects are often unrecognised and unsupported. In the absence of any biomedical sequelae among men such marginalisation may be intensified. Men living through multiple miscarriages may ...

journal_title：BMJ open

authors： Williams HM,Jones LL,Coomarasamy A,Topping AE

更新日期：2020-05-15 00:00:00

abstract：OBJECTIVE:To evaluate the impact of (1) the removal of home access to traditional electronic games or (2) their replacement with active input electronic games, on daily physical activity and sedentary behaviour in children aged 10-12 years. DESIGN:Crossover randomised controlled trial, over 6 months. SETTING:Family h...

journal_title：BMJ open

authors： Straker LM,Abbott RA,Smith AJ

更新日期：2013-07-01 00:00:00

abstract：INTRODUCTION:An increasing number of people are living with cognitive impairment and dementia. Current pharmacological therapies at best reduce Alzheimer's disease symptomatology but do not delay dementia onset in those at high risk. Structured exercise interventions can enhance cognition in older people; however, to p...

journal_title：BMJ open

authors： Macpherson H,Brownell S,Duckham RL,Meyer B,Mirzaee S,Daly RM

更新日期：2019-05-09 00:00:00

abstract：OBJECTIVES:Guidelines and training initiatives (G/TIs) are available to support communication in cross-cultural consultations but are rarely implemented in routine practice in primary care. As part of the European Union RESTORE project, our objective was to explore whether the available G/TIs make sense to migrants and...

journal_title：BMJ open

authors： Lionis C,Papadakaki M,Saridaki A,Dowrick C,O'Donnell CA,Mair FS,van den Muijsenbergh M,Burns N,de Brún T,O'Reilly de Brún M,van Weel-Baumgarten E,Spiegel W,MacFarlane A

更新日期：2016-07-22 00:00:00

abstract：OBJECTIVES:There is growing evidence that antihypertensive agents, particularly centrally acting ACE inhibitors (CACE-Is), which cross the blood-brain barrier, are associated with a reduced rate of cognitive decline. Given this, we compared the rates of cognitive decline in clinic patients with dementia receiving CACE-...

journal_title：BMJ open

authors： Gao Y,O'Caoimh R,Healy L,Kerins DM,Eustace J,Guyatt G,Sammon D,Molloy DW

更新日期：2013-07-25 00:00:00

abstract：OBJECTIVE:The development of cynicism in medicine, defined as a decline in empathy and emotional neutralisation during medical training, is a significant concern for medical educators. We sought to use online medical student discussion groups to provide insight into how cynicism in medicine is perceived, the consequenc...

journal_title：BMJ open

authors： Peng J,Clarkin C,Doja A

更新日期：2018-10-18 00:00:00

abstract：OBJECTIVE:The primary objective was to explore differences in perceived need for care (PNC), mental health services use (MHSU) and perceived sufficiency of care (PSC) between Canadian Armed Forces Regular Force (RegF) and Reserve Force (ResF) personnel with an objective need for mental health services. DESIGN:Data cam...

journal_title：BMJ open

authors： Boulos D,Fikretoglu D

更新日期：2019-09-18 00:00:00

abstract：OBJECTIVE:The evaluation of discomfort in paediatric research is scarcely evidence-based. In this study, we make a start in describing children's self-reported discomfort during common medical research procedures and compare this with discomfort during dental check-ups which can be considered as a reference level of a ...

journal_title：BMJ open

authors： Staphorst MS,Benninga MA,Bisschoff M,Bon I,Busschbach JJV,Diederen K,van Goudoever JB,Haarman EG,Hunfeld JAM,Jaddoe VVW,de Jong KJM,de Jongste JC,Kindermann A,Königs M,Oosterlaan J,Passchier J,Pijnenburg MW,Reneman L,

更新日期：2017-08-01 00:00:00

abstract：OBJECTIVES:Studies on ethnic disparities in glycaemic control have been contradictory, and compromised by excessively broad categories of ethnicity and inadequate adjustment for socioeconomic differences. We aimed to study the effect of ethnicity on glycaemic control in a large cohort of patients with type 2 diabetes. ...

journal_title：BMJ open

authors： Rawshani A,Svensson AM,Rosengren A,Zethelius B,Eliasson B,Gudbjörnsdottir S

更新日期：2015-06-05 00:00:00

abstract：OBJECTIVES:To systematically investigate the prevalence of pain, factors related with pain and pain management interventions in patients with chronic obstructive pulmonary disease (COPD). DESIGN:Systematic review and meta-analysis. DATA SOURCES AND STUDY ELIGIBILITY CRITERIA:PubMed (MEDLINE), EMBASE, CINAHL and Psych...

journal_title：BMJ open

authors： van Dam van Isselt EF,Groenewegen-Sipkema KH,Spruit-van Eijk M,Chavannes NH,de Waal MW,Janssen DJ,Achterberg WP

更新日期：2014-09-26 00:00:00

abstract：OBJECTIVES:The aim of the study was to examine the level of patient satisfaction with nursing care and identify the factors affecting satisfaction from the inpatient's perspective in a backward region of China. DESIGN:This was a cross-sectional study. SETTING:The study was conducted at a tertiary hospital located in ...

journal_title：BMJ open

authors： Zhang J,Yang L,Wang X,Dai J,Shan W,Wang J

更新日期：2020-09-09 00:00:00

abstract：INTRODUCTION:Smell and taste of milk are not generally considered when tube feeding preterm infants. Preterm infants have rapid growth, particularly of the brain, and high caloric needs. Enteral feeding is often poorly tolerated which may lead to growth failure and long-term neurodevelopmental impairment. Smell and tas...

journal_title：BMJ open

authors： Beker F,Macey J,Liley H,Hughes I,Davis PG,Twitchell E,Jacobs S

更新日期：2019-07-17 00:00:00

abstract：OBJECTIVES:The choice of doctor is an important issue for patients with cancer, and the reputation of the doctor is the single most important factor for patients to choose a doctor. Media are providing information about the 'best cancer doctor', but they vary widely in their selection methodology. We investigated cance...

journal_title：BMJ open

authors： Shin DW,Cho J,Yang HK,Kim SY,Lee S,Nam EJ,Chung JS,Im JS,Park K,Park JH

更新日期：2018-05-14 00:00:00

abstract：OBJECTIVES:To understand the experiences of parents of infants who required surgery early in life. To identify messages and training needs for the extended clinical teams caring for these families-including paediatric surgeons, neonatologists, nurses, obstetricians, midwives and sonographers. SETTING:UK-wide interview...

journal_title：BMJ open

authors： Hinton L,Locock L,Long AM,Knight M

更新日期：2018-06-30 00:00:00

abstract：INTRODUCTION:Distress is experienced by the majority of cardiac patients, yet no cardiac-specific measure of distress exists. The aim of this project is to develop and validate the Cardiac Distress Inventory (CDI). Using the CDI, health professionals will be able to identify key clusters of psychological, emotional and...

journal_title：BMJ open

authors： Jackson A,Rogerson M,Le Grande M,Thompson D,Ski C,Alvarenga M,Amerena J,Higgins R,Raciti M,Murphy BM

更新日期：2020-06-11 00:00:00

abstract：OBJECTIVE:To provide insight into the motives for hospital self-referral during office hours and the barriers deterring general practitioner (GP) consultation with a primary care request. SETTING:People who self-referred at a Daytime General Practice Cooperative (GPC) in two hospitals in The Hague, The Netherlands. P...

journal_title：BMJ open

authors： Minderhout RNN,Venema P,Vos HMM,Kant J,Bruijnzeels MA,Numans ME

更新日期：2019-06-06 00:00:00

abstract：INTRODUCTION:Since the emergence in 1997 of the Wellness Recovery Action Plan, a number of other tools developed by users and/or ex-users of mental health services have been published and implemented. All these tools aim to promote self-determination in mental health recovery processes. A scoping review will be carried...

journal_title：BMJ open

authors： Sampietro HM,Carmona VR,Rojo JE,Gómez-Benito J

更新日期：2020-11-12 00:00:00

abstract：OBJECTIVE:To assess the effect of the Pregnant+ app on the 2-hour glucose level of the routine postpartum oral glucose tolerance test (OGTT) among women with gestational diabetes mellitus (GDM). The Pregnant+ app was designed to provide information about GDM, and promote physical activity and a healthy diet. DESIGN:A ...

journal_title：BMJ open

authors： Borgen I,Småstuen MC,Jacobsen AF,Garnweidner-Holme LM,Fayyad S,Noll J,Lukasse M

更新日期：2019-11-11 00:00:00

abstract：OBJECTIVES:This study aims to examine the tracking and predictability of physical activity in old age from overall physical activity and participation in sport, recreational activity and walking in mid-life. DESIGN:Prospective population-based cohort study. SETTING:British Regional Heart Study participants recruited ...

journal_title：BMJ open

authors： Aggio D,Papacosta O,Lennon L,Whincup P,Wannamethee G,Jefferis BJ

更新日期：2017-09-21 00:00:00

abstract：INTRODUCTION:Severe behavioural problems (SBPs) are a common contributor to morbidity and reduced quality of life in children with intellectual disability (ID). Current medication treatment for SBP is associated with a high risk of side effects. Innovative and safe interventions are urgently needed. Anecdotal reports a...

journal_title：BMJ open

authors： Efron D,Taylor K,Payne JM,Freeman JL,Cranswick N,Mulraney M,Prakash C,Lee KJ,Williams K

更新日期：2020-03-08 00:00:00

abstract：:Objectives Eosinophilic oesophagitis (EO) shows eosinophilic infiltration of the mucosa and can present with symptoms indistinguishable from gastrooesophageal reflux disease (GORD). The authors describe the clinical, endoscopic and histopathological features of all cases of histological EO presenting during 2007-2008 ...

journal_title：BMJ open

authors： Cohen MC,Rao P,Thomson M,Al-Adnani M

更新日期：2012-01-12 00:00:00

abstract：OBJECTIVE:To study the incidence of de novo multimorbidity across all ages in a geographically defined population with an emphasis on sex and ethnic differences. DESIGN:Historical cohort study. SETTING:All persons residing in Olmsted County, Minnesota, USA on 1 January 2000 who had granted permission for their record...

journal_title：BMJ open

authors： St Sauver JL,Boyd CM,Grossardt BR,Bobo WV,Finney Rutten LJ,Roger VL,Ebbert JO,Therneau TM,Yawn BP,Rocca WA

更新日期：2015-02-03 00:00:00

abstract：OBJECTIVES:To estimate the present value of current and future funding needed for HIV treatment and prevention in 9 sub-Saharan African (SSA) countries that account for 70% of HIV burden in Africa under different scenarios of intervention scale-up. To analyse the gaps between current expenditures and funding obligation...

journal_title：BMJ open

authors： Atun R,Chang AY,Ogbuoji O,Silva S,Resch S,Hontelez J,Bärnighausen T

更新日期：2016-03-06 00:00:00

abstract：OBJECTIVES:Walking is an adaptable, inexpensive and accessible form of physical activity. However, its impact on quality of life (QoL) and symptom severity in people with advanced cancer is unknown. This study aimed to assess the feasibility and acceptability of a randomised controlled trial (RCT) of a community-based ...

journal_title：BMJ open

authors： Tsianakas V,Harris J,Ream E,Van Hemelrijck M,Purushotham A,Mucci L,Green JS,Fewster J,Armes J

更新日期：2017-02-15 00:00:00