Lithium for Fracture Treatment (LiFT): a double-blind randomised control trial protocol.

abstract：:Objectives In 2007, the International Agency for Research on Cancer classified long-term shift work as a probable carcinogen, with the strongest evidence for breast cancer. One proposed mechanism involves night-time light exposure and decreases in melatonin, a circadian rhythmic hormone. It is hypothesised that melato...

journal_title：BMJ open

authors： Langley AR,Graham CH,Grundy AL,Tranmer JE,Richardson H,Aronson KJ

更新日期：2012-01-21 00:00:00

abstract：OBJECTIVE:Many studies have demonstrated that elevated serum uric acid (SUA) level is linked with metabolic syndrome (MetS). However, whether there is a sex difference in the association between SUA and MetS has not been determined. This study aimed to accurately explore the impact of SUA longitudinal changes on MetS b...

journal_title：BMJ open

authors： Liu Y,Fan Y,Liu Q,Liu K,Chen F,Tang X,Li G,Hu D,Song G

更新日期：2020-07-02 00:00:00

abstract：INTRODUCTION:The prevalence of disordered gambling worldwide has been estimated at 2.3%. Only a small minority of disordered gamblers seek specialist face-to-face treatment, and so a need for alternative treatment delivery models that capitalise on advances in communication technology, and use self-directed activity th...

journal_title：BMJ open

authors： Merkouris SS,Rodda SN,Austin D,Lubman DI,Harvey P,Battersby M,Cunningham J,Lavis T,Smith D,Dowling NA

更新日期：2017-02-23 00:00:00

abstract：OBJECTIVES:To assess people's procedural preferences for making medical surrogate decisions, from the perspectives of both a potential surrogate and an incapacitated patient. DESIGN:Computer-assisted telephone interviews. Respondents were randomly assigned either the role of an incapacitated patient or that of a poten...

journal_title：BMJ open

authors： Frey R,Herzog SM,Hertwig R

更新日期：2018-07-25 00:00:00

abstract：OBJECTIVES:Few studies have investigated the prevalence of adverse drug reactions (ADRs) leading to hospitalisation in Japan. The aim of this study was to determine the prevalence of ADRs leading to hospitalisation and to evaluate the preventability of these ADRs in Japan. DESIGN:A single-centre cross-sectional study ...

journal_title：BMJ open

authors： Komagamine J,Kobayashi M

更新日期：2019-08-05 00:00:00

abstract：INTRODUCTION:An increasing number of patients survive sepsis; however, we lack valid data on the long-term impact on morbidity from prospective observational studies. Therefore, we designed an observational cohort to quantify mid-term and long-term functional disabilities after intensive care unit (ICU)-treated sepsis....

journal_title：BMJ open

authors： Scherag A,Hartog CS,Fleischmann C,Ouart D,Hoffmann F,König C,Kesselmeier M,Fiedler S,Philipp M,Braune A,Eichhorn C,Gampe C,Romeike H,Reinhart K,Mid-German Sepsis Cohort investigators.

更新日期：2017-08-23 00:00:00

abstract：OBJECTIVES:To explore staff experiences of working with a digital communication platform implemented throughout several primary healthcare centres in Sweden. DESIGN:A descriptive qualitative approach using focus group interviews. Qualitative content analysis was used to code, categorise and thematise data. SETTING:Pr...

journal_title：BMJ open

authors： Entezarjou A,Bolmsjö BB,Calling S,Midlöv P,Milos Nymberg V

更新日期：2020-07-23 00:00:00

abstract：OBJECTIVE:To investigate timely access to palliative medicines/drugs (PMs) from community pharmacies to inform palliative care service delivery. DESIGN:Mixed methods in two sequential phases: (1) prospective audit of prescriptions and concurrent survey of patients/representatives collecting PMs from pharmacy and (2) i...

journal_title：BMJ open

authors： Miller EJ,Morgan JD,Blenkinsopp A

更新日期：2019-11-24 00:00:00

abstract：OBJECTIVE:Lung cancer is increasingly recognised as a heterogeneous disease. Recent advances with targeted therapies for lung cancer with oncogenic mutations have greatly improved the prognosis for this subset of patients, yet little is known about their experiences. This study aimed to identify the needs and explore t...

journal_title：BMJ open

authors： Al Achkar M,Marchand L,Thompson M,Chow LQM,Revere D,Baldwin LM

更新日期：2020-03-23 00:00:00

abstract：INTRODUCTION:Women who have pathogenic mutations in the BRCA1 and BRCA2 genes are at greatly increased risks for breast and ovarian cancers. Although risk-reduction strategies can be undertaken by these women, knowledge regarding the uptake of these strategies is limited. Additionally, the healthcare behaviours of wome...

journal_title：BMJ open

authors： Dossa F,Cusimano MC,Sutradhar R,Metcalfe K,Little T,Lerner-Ellis J,Eisen A,Meschino WS,Baxter NN

更新日期：2018-09-04 00:00:00

abstract：OBJECTIVES:Patient experience is being widely considered in the evaluation of healthcare service quality, which is a key target for public hospitals under China's New Healthcare Reform. This study aimed to illustrate patients' experiences in county-level public hospitals, and identify aspects that need to be improved. ...

journal_title：BMJ open

authors： Min R,Li L,Zi C,Fang P,Wang B,Tang C

更新日期：2019-11-14 00:00:00

abstract：OBJECTIVES:To assess changes in depressive symptoms and health-related quality of life (HRQOL) after screening for cognitive impairment in people with type 2 diabetes. DESIGN:A prospective cohort study, part of the Cognitive Impairment in Diabetes (Cog-ID) study. SETTING:Participants were screened for cognitive impai...

journal_title：BMJ open

authors： Janssen J,Koekkoek PS,Biessels GJ,Kappelle JL,Rutten GEHM,Cog-ID study group.

更新日期：2019-01-17 00:00:00

abstract：INTRODUCTION:Secondary prevention drugs for cardiac disease have been demonstrated by clinical trials to be effective in reducing future cardiovascular and mortality events (WAMACH is the Western Australian Medication Adherence and Costs in Heart disease study). Hence, most countries have adopted health policies and gu...

journal_title：BMJ open

authors： Gunnell AS,Knuiman MW,Geelhoed E,Hobbs MS,Katzenellenbogen JM,Hung J,Rankin JM,Nedkoff L,Briffa TG,Ortiz M,Gillies M,Cordingley A,Messer M,Gardner C,Lopez D,Atkins E,Mai Q,Sanfilippo FM

更新日期：2014-09-18 00:00:00

abstract：INTRODUCTION:An increasing number of people are living with cognitive impairment and dementia. Current pharmacological therapies at best reduce Alzheimer's disease symptomatology but do not delay dementia onset in those at high risk. Structured exercise interventions can enhance cognition in older people; however, to p...

journal_title：BMJ open

authors： Macpherson H,Brownell S,Duckham RL,Meyer B,Mirzaee S,Daly RM

更新日期：2019-05-09 00:00:00

abstract：OBJECTIVES:This study aimed to assess the knowledge of risk factors and warning symptoms and attitude towards gastric cancer screening among the general population in China. SETTING:Hunan province, China PARTICIPANTS: Individuals aged older than 18 years were recruited using a cluster sampling method. DESIGN:A cross-...

journal_title：BMJ open

authors： Liu Q,Zeng X,Wang W,Huang RL,Huang YJ,Liu S,Huang YH,Wang YX,Fang QH,He G,Zeng Y

更新日期：2019-07-23 00:00:00

abstract：BACKGROUND:Birth weight is a critical indicator of neonatal health and foretells people's health in adolescence and even adulthood. Some researchers have warned against the adverse effects on babies' birth weight of exposure to pollutants in interior decoration or oil paint by odour intake. This study evaluated the eff...

journal_title：BMJ open

authors： Liu H,Chen S,Zhu H,Yang H,Gong F,Wang L,Jiang Y,Lian BQ,Yan C,Li J,Wang Q,Zhang S,Pan H

更新日期：2017-08-21 00:00:00

abstract：OBJECTIVES:To explore the usefulness of Bioelectrical Impedance Analysis (BIA) for general use by identifying best-evidenced formulae to calculate lean and fat mass, comparing these to historical gold standard data and comparing these results with machine-generated output. In addition, we explored how to best to adjust...

journal_title：BMJ open

authors： Franco-Villoria M,Wright CM,McColl JH,Sherriff A,Pearce MS,Gateshead Millennium Study core team.

更新日期：2016-01-07 00:00:00

abstract：OBJECTIVE:Brain tumours are relatively rare but hold a significant place in cancer rehabilitation due to their pronounced disabling capacity to promote physical, cognitive and psychosocial sequelae. This small-scale qualitative study used coping and motivational theories to gain understanding and knowledge of patients'...

journal_title：BMJ open

authors： Fahrenholtz ML,Hansen A,Søgaard K,Andersen LN

更新日期：2019-12-08 00:00:00

abstract：OBJECTIVES:To identify and evaluate interventions aimed at increasing uptake of, or access to, physical health screening by adults with severe mental illness; to examine why interventions might work. DESIGN:Realist review. SETTING:Primary, secondary and tertiary care. RESULTS:A systematic search identified 1448 stud...

journal_title：BMJ open

authors： Lamontagne-Godwin F,Burgess C,Clement S,Gasston-Hales M,Greene C,Manyande A,Taylor D,Walters P,Barley E

更新日期：2018-02-10 00:00:00

abstract：INTRODUCTION:The Bristol Stool Form Scale (BSS) which consists of 7 photographs of different stool forms allows assessment of stool consistency (scale 1 for hard lumps to scale 7 for watery stools), in an objective manner in adults. The BSS is also sometimes used to characterise the stools of infants and young children...

journal_title：BMJ open

authors： Vandenplas Y,Szajewska H,Benninga M,Di Lorenzo C,Dupont C,Faure C,Miqdadi M,Osatakul S,Ribes-Konickx C,Saps M,Shamir R,Staiano A,BITSS Study Group.

更新日期：2017-03-29 00:00:00

abstract：OBJECTIVES:The Republic of Korea (Korea) has experienced a steady increase in the number of births from immigrant women over the last 20 years. However, little is known about the birth outcomes of immigrant women in Korea. This study compared Korean birth data from immigrant and native women who married native men, and...

journal_title：BMJ open

authors： Song IG,Kim MS,Shin SH,Kim EK,Kim HS,Choi S,Kwon S,Park SM

更新日期：2017-09-24 00:00:00

abstract：INTRODUCTION:In Ethiopia, undernutrition is the common public health concern, swaying the lives of lots of adolescent girls. Its sequelae are not only limited to them, but rather their upcoming offspring are vulnerable too. Even though some studies have been carried out in different parts of the country, the national p...

journal_title：BMJ open

authors： Takele WW,Muche AA,Mekonnen ZA,Ambaw YF,Wagnew F

更新日期：2019-05-22 00:00:00

abstract：INTRODUCTION:Anaemia is a major global health problem affecting about 43% of preschool children globally and 60% of 6-24-month-old children in rural Bangladesh, half of which is attributed to iron deficiency (ID). Although WHO recommends universal supplementation with iron or home fortification with iron-containing mul...

journal_title：BMJ open

authors： Hasan MI,Hossain SJ,Braat S,Dibley MJ,Fisher J,Grantham-McGregor S,Tofail F,Simpson JA,Arifeen SE,Hamadani J,Biggs BA,Pasricha SR

更新日期：2017-11-15 00:00:00

abstract：OBJECTIVE:To estimate the impact of state-level supplements of the Earned Income Tax Credit (EITC) on mortality in the USA. The EITC supplements the wages of lower-income workers by providing larger returns when taxes are filed. SETTING:Nationwide sample spanning 25 cohorts of people across every state in the USA. PA...

journal_title：BMJ open

authors： Muennig P,Vail D,Hakes JK

更新日期：2020-08-20 00:00:00

abstract：OBJECTIVES:To identify the top 10 unanswered research questions for primary care patient safety research. DESIGN:A modified nominal group technique. SETTING:UK. PARTICIPANTS:Anyone with experience of primary care including: patients, carers and healthcare professionals. 341 patients and 86 healthcare professionals s...

journal_title：BMJ open

authors： Morris RL,Stocks SJ,Alam R,Taylor S,Rolfe C,Glover SW,Whitcombe J,Campbell SM

更新日期：2018-02-28 00:00:00

abstract：OBJECTIVES:To examine the damage location distribution of five main body region injuries of maximum abbreviated injury score (MAIS) 3-6 injured occupants for nearside struck vehicle in front-to-side impact crashes. DESIGN AND SETTING:MAIS 3-6 injured occupants information was extracted from the US-National Automotive ...

journal_title：BMJ open

authors： Tang Y,Cao L,Kan S

更新日期：2014-05-08 00:00:00

abstract：OBJECTIVES:Novel therapeutics are an important part of ophthalmologists' armamentarium, and the risks and benefits of these therapies must be carefully evaluated. We sought to quantify the characteristics of the pivotal clinical trials supporting the regulatory approval of new ophthalmic drugs and medical devices. DES...

journal_title：BMJ open

authors： Hwang J,Hwang TJ,Ciolino JB

更新日期：2015-06-04 00:00:00

abstract：OBJECTIVE:To report on the relative cost-effectiveness of total hip arthroplasty and resurfacing arthroplasty (replacement of articular surface of femoral head only) in patients with severe arthritis suitable for hip joint resurfacing arthroplasty. DESIGN:Cost-effectiveness analysis on an intention-to-treat basis of a...

journal_title：BMJ open

authors： Edlin R,Tubeuf S,Achten J,Parsons N,Costa M

更新日期：2012-10-12 00:00:00

abstract：INTRODUCTION:The incidence of head and neck cancer (HNC) in the UK is rising, with an average of 31 people diagnosed daily. Patients affected by HNC suffer significant short-term and long-term post-treatment morbidity as a result of dysphagia, which affects daily functioning and quality of life (QOL). Pretreatment swal...

journal_title：BMJ open

authors： Govender R,Smith CH,Gardner B,Barratt H,Taylor SA

更新日期：2017-03-27 00:00:00

abstract：INTRODUCTION:Cardiac rehabilitation (CR) reduces all-cause and cardiovascular mortality in patients with coronary heart disease (CHD). Much of this improvement has been attributed to the beneficial effects of structured exercise training. However, UK-based studies have not confirmed this. Improvements in survival and c...

journal_title：BMJ open

authors： Nichols S,Nation F,Goodman T,Clark AL,Carroll S,Ingle L

更新日期：2018-01-27 00:00:00