Abstract：
BACKGROUND:Visceral leishmaniasis (VL) is a neglected disease that is spread to humans by the bites of infected female phlebotomine sand flies. Although this vector-borne disease has been eliminated in most parts of China, it still poses a significant public health burden in the Xinjiang Uygur Autonomous Region. Understanding of the spatial epidemiology of the disease remains vague in the local community. In the present study, we investigated the spatiotemporal distribution of VL in the region in order to assess the potential threat of the disease. METHODS:Based on comprehensive infection records, the spatiotemporal patterns of new cases of VL in the region between 2005 and 2015 were analysed. By combining maps of environmental and socioeconomic correlates, the boosted regression tree (BRT) model was adopted to identify the environmental niche of VL. RESULTS:The fitted BRT models were used to map potential infection risk zones of VL in the Xinjiang Uygur Autonomous Region, revealing that the predicted high infection risk zones were mainly concentrated in central and northern Kashgar Prefecture, south of Atushi City bordering Kashgar Prefecture and regions of the northern Bayingolin Mongol Autonomous Prefecture. The final result revealed that approximately 16.64 million people inhabited the predicted potential infection risk areas in the region. CONCLUSIONS:Our results provide a better understanding of the potential endemic foci of VL in the Xinjiang Uygur Autonomous Region with a 1 km spatial resolution, thereby enhancing our capacity to target the potential risk areas, to develop disease control strategies and to allocate medical supplies.
journal_name
Parasit Vectorsjournal_title
Parasites & vectorsauthors
Ding F,Wang Q,Fu J,Chen S,Hao M,Ma T,Zheng C,Jiang Ddoi
10.1186/s13071-019-3778-zsubject
Has Abstractpub_date
2019-11-08 00:00:00pages
528issue
1issn
1756-3305pii
10.1186/s13071-019-3778-zjournal_volume
12pub_type
杂志文章abstract：BACKGROUND:Toxocara canis is the causative agent of toxocariasis of humans and other animals. This parasitic nematode (roundworm) has a complex life cycle, in which substantial developmental changes and switches occur. As small non-coding RNAs (sRNAs) are key regulators of gene expression in a wide range of organisms, ...
journal_title：Parasites & vectors
pub_type： 杂志文章
doi：10.1186/s13071-016-1508-3
更新日期：2016-04-23 00:00:00
abstract：BACKGROUND:The preventive effect of fluralaner spot-on solution against transmission of Babesia canis by Dermacentor reticulatus ticks was evaluated. FINDINGS:Sixteen dogs, tested negative for B. canis by polymerase chain reaction (PCR) and immunofluorescence assay test (IFAT), were allocated to two study groups. On d...
journal_title：Parasites & vectors
pub_type： 杂志文章
doi：10.1186/s13071-016-1481-x
更新日期：2016-05-31 00:00:00
abstract：BACKGROUND:Leishmaniasis is a major parasitic disease worldwide, except in Australia and Antarctica, and it poses a significant public health problem. Due to the absence of safe and effective vaccines and drugs, researchers have begun an extensive search for new drugs. The aim of the current study was to investigate th...
journal_title：Parasites & vectors
pub_type： 杂志文章
doi：10.1186/s13071-020-04543-y
更新日期：2021-01-11 00:00:00
abstract：BACKGROUND:Trypanosomosis is a haemoprotozoan disease, mostly transmitted by the tsetse fly (Glossina spp.), it causes severe disease in humans and animals in Sub-Saharan Africa (SSA). The disease results in loss of livestock and agricultural productivity with severe socio-economic impacts. In Ethiopia, bovine trypanos...
journal_title：Parasites & vectors
pub_type： 杂志文章,meta分析
doi：10.1186/s13071-016-1404-x
更新日期：2016-03-10 00:00:00
abstract：BACKGROUND:The studies reported here were conducted to ascertain the efficacy of imidacloprid/flumethrin incorporated in a slow-release matrix collar, against infestations of dogs by fleas, ticks, mites and lice. Efficacy was evaluated against the flea Ctenocephalides felis felis, the ticks Rhipicephalus sanguineus, Ix...
journal_title：Parasites & vectors
pub_type： 杂志文章,随机对照试验
doi：10.1186/1756-3305-5-102
更新日期：2012-05-30 00:00:00
abstract：BACKGROUND:Recent global changes have led to an increase in distribution of ticks towards higher elevation and latitude in Europe and livestock are at increasing risk of contracting tick-borne diseases, but psychological aspects of how this affects human well-being are rarely assessed. Departing from the theory on emot...
journal_title：Parasites & vectors
pub_type： 杂志文章
doi：10.1186/s13071-020-04162-7
更新日期：2020-06-30 00:00:00
abstract：BACKGROUND:Pyrethroid resistance in African vector mosquitoes is a threat to malaria control. Resistant mosquitoes can survive insecticide doses that would normally be lethal. We studied effects of such doses on Plasmodium falciparum development inside kdr-resistant Anopheles gambiae s.s. in Uganda. METHODS:We collect...
journal_title：Parasites & vectors
pub_type： 杂志文章
doi：10.1186/s13071-016-1384-x
更新日期：2016-02-24 00:00:00
abstract：BACKGROUND:The Smad proteins function in TGF-β signalling transduction. In the model nematode Caenorhabditis elegans, the co-Smad, DAF-3 mediates R-Smads and performs a central role in DAF-7 signal transduction, regulating dauer formation and reproductive processes. Considering the divergent evolutionary patterns of th...
journal_title：Parasites & vectors
pub_type： 杂志文章
doi：10.1186/s13071-019-3855-3
更新日期：2019-12-27 00:00:00
abstract：BACKGROUND:Taenia ovis is a tapeworm that is mainly transmitted between dogs and sheep. Although T. ovis infection is not a public health issue, it causes a great financial loss due to condemnation of carcasses. The first outbreak of T. ovis infection in China occurred in 2015. Reassessment of adverse effects of T. ov...
journal_title：Parasites & vectors
pub_type： 信件
doi：10.1186/s13071-016-1700-5
更新日期：2016-07-26 00:00:00
abstract：BACKGROUND:Spatial modelling studies of schistosomiasis (SCH) are now commonplace. Covariate values are commonly extracted at survey locations, where infection does not always take place, resulting in an unknown positional exposure mismatch. The present research aims to: (i) describe the nature of the positional exposu...
journal_title：Parasites & vectors
pub_type： 杂志文章
doi：10.1186/s13071-018-3039-6
更新日期：2018-08-13 00:00:00
abstract：BACKGROUND:Cutaneous Leishmaniasis (CL) is endemic in Sudan. It is caused by Leishmania major parasites and transmitted by Phlebotomus papatasi sandflies. Recently, uncommon clinical manifestations of CL have been reported. Moreover, L. donovani parasites that cause Visceral Leishmaniasis (VL) have been isolated from C...
journal_title：Parasites & vectors
pub_type： 杂志文章
doi：10.1186/1756-3305-5-249
更新日期：2012-11-12 00:00:00
abstract：BACKGROUND:One of the major issues concerning disease ecology and conservation is knowledge of the factors that influence the distribution of parasites and consequently disease outbreaks. This study aimed to investigate avian haemosporidian composition and the distribution of these parasites in three altitudinally sepa...
journal_title：Parasites & vectors
pub_type： 杂志文章
doi：10.1186/1756-3305-6-139
更新日期：2013-05-07 00:00:00
abstract：BACKGROUND:Understanding mosquito resting behaviour is important for the control of vector-borne diseases, but this remains a challenge because of the paucity of efficient sampling tools. We evaluated two novel sampling methods in the field: the Sticky Resting Box (SRB) and the Resting Bucket trap (RBu) to test their e...
journal_title：Parasites & vectors
pub_type： 杂志文章
doi：10.1186/s13071-015-1066-0
更新日期：2015-09-17 00:00:00
abstract：BACKGROUND:Mathematical models of parasite transmission can help integrate a large body of information into a consistent framework, which can then be used for gaining mechanistic insights and making predictions. However, uncertainty, spatial variability and complexity, can hamper the use of such models for decision mak...
journal_title：Parasites & vectors
pub_type： 杂志文章
doi：10.1186/s13071-015-1132-7
更新日期：2015-10-22 00:00:00
abstract：BACKGROUND:Malaria mosquitoes spend a considerable part of their life in the aquatic stage, rendering them vulnerable to interventions directed to aquatic habitats. Recent successes of mosquito larval control have been reported using environmental and biological tools. Here, we report the effects of shading by plants a...
journal_title：Parasites & vectors
pub_type： 杂志文章
doi：10.1186/1756-3305-4-130
更新日期：2011-07-06 00:00:00
abstract：BACKGROUND:Culex pipiens L. is the most widespread mosquito vector in temperate regions including North Africa. Cx. pipiens has two recognized forms or biotypes; pipiens and molestus are morphologically indistinguishable with distinct behavior and physiology that may influence their vectorial status. In our study, we p...
journal_title：Parasites & vectors
pub_type： 杂志文章
doi：10.1186/1756-3305-5-83
更新日期：2012-04-27 00:00:00
abstract：BACKGROUND:Tick-borne infections are no longer confined to rural areas, they are documented with increasing frequency in urban settlements across the world. They are known to cause diseases in humans as well as in their companion animals. METHODS:During a period of 2 years, from January 2013 until December 2014, ticks...
journal_title：Parasites & vectors
pub_type： 杂志文章
doi：10.1186/s13071-016-1632-0
更新日期：2016-06-21 00:00:00
abstract：BACKGROUND:Aedes albopictus (Skuse) is an invasive mosquito that has become an important vector of chikungunya, dengue and Zika viruses. In the absence of specific antiviral therapy or a vaccine, vector management is the sole method available for reducing Aedes-induced disease morbidity. Determining the resistance stat...
journal_title：Parasites & vectors
pub_type： 杂志文章
doi：10.1186/s13071-017-2581-y
更新日期：2018-01-03 00:00:00
abstract：BACKGROUND:Angiostrongylus cantonensis is an important causative agent of eosinophilic meningitis and eosinophilic meningoencephalitis in humans. Previous studies have shown that the Sonic hedgehog (Shh) signaling pathway may reduce cell apoptosis by inhibiting oxidative stress in A. cantonensis infection. In this stud...
journal_title：Parasites & vectors
pub_type： 杂志文章
doi：10.1186/s13071-017-2385-0
更新日期：2017-09-26 00:00:00
abstract：BACKGROUND:The genus Marshallagia (Family Haemonchidae, subfamily Ostertagiinae) contains multiple species of nematodes parasitising the abomasum (or duodenum) of ruminants, in particular of Caprinae. Male specimens have been described to be polymorphic with the frequent/major morphotype initially described in the genu...
journal_title：Parasites & vectors
pub_type： 杂志文章
doi：10.1186/s13071-020-04265-1
更新日期：2020-08-12 00:00:00
abstract：BACKGROUND:Invasive mosquito species (IMS) of the genus Aedes are a cause of increasing concern in Europe owing to their ability to vector important human viral diseases. Entomological surveillance to early detect alien mosquito and flavivirus circulation in Liguria, northwest Italy, has been carried out since 2011. R...
journal_title：Parasites & vectors
pub_type： 杂志文章
doi：10.1186/s13071-019-3589-2
更新日期：2019-07-05 00:00:00
abstract：BACKGROUND:Schistosoma japonicum is a parasitic flatworm that causes human schistosomiasis. Secreted extracellular vesicles (EVs) play a key role in pathogen-host interfaces. Previous studies have shown that S. japonicum adult worms can release microRNA (miRNA)-containing EVs, which can transfer their cargo to mammalia...
journal_title：Parasites & vectors
pub_type： 杂志文章
doi：10.1186/s13071-016-1845-2
更新日期：2016-11-08 00:00:00
abstract：BACKGROUND:Melophagus ovinus (Diptera: Hippoboscidae), a hematophagous ectoparasite, is mainly found in Europe, Northwestern Africa, and Asia. This wingless fly infests sheep, rabbits, and red foxes, and causes inflammation, wool loss and skin damage. Furthermore, this parasite has been shown to transmit diseases, and ...
journal_title：Parasites & vectors
pub_type： 杂志文章
doi：10.1186/s13071-016-1885-7
更新日期：2016-11-25 00:00:00
abstract：BACKGROUND:The argasid tick Ornithodoros erraticus is the vector of African swine fever virus and of several Borrelia species that cause human relapsing fever in the Iberian Peninsula. The tick midgut is part of the ectoparasite-host interface and expresses proteins that are vital for the survival of the tick. Midgut p...
journal_title：Parasites & vectors
pub_type： 杂志文章
doi：10.1186/s13071-015-1148-z
更新日期：2015-10-12 00:00:00
abstract：BACKGROUND:Cues that guide gravid Anopheles gambiae sensu lato to oviposition sites can be manipulated to create new strategies for monitoring and controlling malaria vectors. However, progress towards identifying such cues is slow in part due to the lack of appropriate tools for investigating long-range attraction to ...
journal_title：Parasites & vectors
pub_type： 杂志文章
doi：10.1186/s13071-015-0916-0
更新日期：2015-06-03 00:00:00
abstract：BACKGROUND:West Nile virus (WNV) is a Flavivirus transmitted to vertebrate hosts by mosquitoes, maintained in nature through an enzootic bird-mosquito cycle. In Europe the virus became of major public health and veterinary concern in the 1990s. In Italy, WNV re-emerged in 2008, ten years after the previous outbreak and...
journal_title：Parasites & vectors
pub_type： 杂志文章
doi：10.1186/s13071-015-1031-y
更新日期：2015-08-13 00:00:00
abstract：BACKGROUND:Dirofilaria immitis and Dirofilaria repens are transmitted by bloodsucking culicid mosquitoes belonging to Culex, Aedes, Ochlerotatus, Anopheles and Mansonia genera. The detection of filarioids in mosquitoes for assessing distribution of vectors and/or of pathogens in a given area (also known as "xenomonitor...
journal_title：Parasites & vectors
pub_type： 杂志文章
doi：10.1186/1756-3305-5-76
更新日期：2012-04-20 00:00:00
abstract：BACKGROUND:Acanthamoebiasis is most often found in patients with immune deficiency, with infections facilitated by the intake of immunosuppressive drugs. The host immune response to Acanthamoeba spp. infection is poorly understood. Thus, in this study, we aimed to examine the course of Acanthamoeba spp. infection takin...
journal_title：Parasites & vectors
pub_type： 杂志文章
doi：10.1186/s13071-018-3108-x
更新日期：2018-09-20 00:00:00
abstract：BACKGROUND:The basic function of the immune system is to protect an organism against infection in order to minimize the fitness costs of being infected. According to life-history theory, energy resources are in a trade-off between the costly demands of immunity and other physiological demands. Concerning fish, both phy...
journal_title：Parasites & vectors
pub_type： 杂志文章
doi：10.1186/1756-3305-4-120
更新日期：2011-06-27 00:00:00
abstract：BACKGROUND:NOD-like receptor protein 3 (NLRP3) inflammasome was reported as expressed in schistosomiasis-induced liver fibrosis (SSLF). We used an NLRP3 inflammasome inhibitor, MCC950, to investigate whether it inhibited liver fibrosis, and explored the preliminary molecular mechanism. METHODS:BALB/c mice were infecte...
journal_title：Parasites & vectors
pub_type： 杂志文章
doi：10.1186/s13071-018-3223-8
更新日期：2019-01-11 00:00:00
