Randomised controlled trial conducted in injecting equipment provision sites to compare the effectiveness of different hepatitis C treatment regimens in people who inject drugs: A Direct obserVed therApy versus fortNightly CollEction study for HCV treatme

abstract：INTRODUCTION:Chronic lower back pain (CLBP) is a major healthcare problem with wide ranging effects. It is a priority for appropriate management of CLBP to get individuals back to work as early as possible. Interventions that identify biopsychosocial barriers to recovery have been observed to lead to successfully reduc...

journal_title：BMJ open

authors： Dwyer CP,Durand H,MacNeela P,Reynolds B,Hamm RM,Main CJ,O'Connor LL,Conneely S,Taheny D,Slattery BW,O'Neill C,NicGabhainn S,Murphy AW,Kropmans T,McGuire BE

更新日期：2016-05-26 00:00:00

abstract：OBJECTIVES:To determine the proportion of maternal and perinatal mortality and morbidity cases, identified by the Perinatal and Maternal Mortality Review Committee (PMMRC), that are also reported within the annual serious adverse events (SAEs) reports published by the Health Quality and Safety Commission (HQSC). SETTI...

journal_title：BMJ open

authors： Farquhar C,Armstrong S,Kim B,Masson V,Sadler L

更新日期：2015-07-23 00:00:00

abstract：OBJECTIVE:Concerns have been raised regarding the quality and completeness of abstract reporting in evidence reviews, but this had not been evaluated in meta-analyses of diagnostic accuracy. Our objective was to evaluate reporting quality and completeness in abstracts of systematic reviews with meta-analyses of depress...

journal_title：BMJ open

authors： Rice DB,Kloda LA,Shrier I,Thombs BD

更新日期：2016-11-18 00:00:00

abstract：INTRODUCTION:Mobility limitation is common and often results from neurological and musculoskeletal health conditions, ageing and/or physical inactivity. In consultation with consumers, clinicians and policymakers, we have developed two affordable and scalable intervention packages designed to enhance physical activity ...

journal_title：BMJ open

authors： Hassett L,Tiedemann A,Hinman RS,Crotty M,Hoffmann T,Harvey L,Taylor NF,Greaves C,Treacy D,Jennings M,Milat A,Bennell KL,Howard K,van den Berg M,Pinheiro M,Wong S,Kirkham C,Ramsay E,O'Rourke S,Sherrington C

更新日期：2020-11-03 00:00:00

abstract：INTRODUCTION:Asthma-related morbidity and mortality in the UK is higher than elsewhere in Europe. Although the reasons for this are largely unclear, one explanation could be a higher prevalence of poorly controlled asthma in the UK. Findings from our earlier study found that, in a sample of 766 children with asthma, 45...

journal_title：BMJ open

authors： Harris K,Mosler G,Grigg J

更新日期：2019-04-23 00:00:00

abstract：BACKGROUND:Mentoring is frequently suggested as an intervention to address gender inequalities in the workplace. OBJECTIVES:To systematically review evidence published since a definitive review in 2006 on the effectiveness of mentoring interventions aimed at achieving gender equality in academic medicine. DESIGN:Syst...

journal_title：BMJ open

authors： House A,Dracup N,Burkinshaw P,Ward V,Bryant LD

更新日期：2021-01-26 00:00:00

abstract：OBJECTIVE:To investigate if continuation rates in first-time users of oral hormonal contraceptives differed between different formulations and to measure if the rates were related to the prescribing categories, that is, physicians and midwives. DESIGN:A longitudinal national population-based registry study. SETTING:T...

journal_title：BMJ open

authors： Josefsson A,Wiréhn AB,Lindberg M,Foldemo A,Brynhildsen J

更新日期：2013-10-18 00:00:00

abstract：OBJECTIVES:To identify the reasons why some people do not participate in bowel cancer screening so that steps can be taken to improve informed decision-making. DESIGN:Qualitative study, using focus groups with thematic analysis of data to identify, analyse and report patterns. Transcripts were repeatedly read and indu...

journal_title：BMJ open

authors： Bradley DT,Treanor C,McMullan C,Owen T,Graham A,Anderson D

更新日期：2015-09-09 00:00:00

abstract：OBJECTIVES:To evaluate surgical experience among current doctors appointed into ophthalmology training posts since the introduction of the Modernising Medical Careers programme. Additionally, to identify regional variations in surgical experience and training programme delivery. DESIGN:A cross-sectional survey. SETTI...

journal_title：BMJ open

authors： Rodrigues IA,Symes RJ,Turner S,Sinha A,Bowler G,Chan WH

更新日期：2013-05-06 00:00:00

abstract：INTRODUCTION:School canteens represent an opportune setting in which to deliver public health nutrition strategies given their wide reach, and frequent use by children. Online school canteen ordering systems, where students order and pay for their lunch online, provide an avenue to improve healthy canteen purchases thr...

journal_title：BMJ open

authors： Delaney T,Wyse R,Yoong SL,Sutherland R,Wiggers J,Ball K,Campbell K,Rissel C,Wolfenden L

更新日期：2017-04-17 00:00:00

abstract：:Objectives Diagnoses-specific sickness certification guidelines were recently introduced in Sweden. The aim of this study was to investigate to which extent general practitioners (GPs) used these guidelines and how useful they found them, 1 year after introduction. Design A cross-sectional questionnaire study. A comp...

journal_title：BMJ open

authors： Skånér Y,Nilsson GH,Arrelöv B,Lindholm C,Hinas E,Wilteus AL,Alexanderson K

更新日期：2011-12-20 00:00:00

abstract：OBJECTIVE:To investigate whether two primary care activities that are framed as indicators of primary care quality (comprehensive care plans and annual reviews of physical health) influence unplanned utilisation of hospital services for people with serious mental illness (SMI). DESIGN, SETTING, PARTICIPANTS:Retrospect...

journal_title：BMJ open

authors： Ride J,Kasteridis P,Gutacker N,Kronenberg C,Doran T,Mason A,Rice N,Gravelle H,Goddard M,Kendrick T,Siddiqi N,Gilbody S,Dare CR,Aylott L,Williams R,Jacobs R

更新日期：2018-11-28 00:00:00

abstract：OBJECTIVE:The aims of this point-prevalence study were to investigate a representative inpatient population to determine the prevalence of people admitted to hospital for the reason of a foot-related condition, and identify associated independent factors. METHODS:Participants were adult inpatients in 5 different repre...

journal_title：BMJ open

authors： Lazzarini PA,Hurn SE,Kuys SS,Kamp MC,Ng V,Thomas C,Jen S,Kinnear EM,d'Emden MC,Reed L

更新日期：2016-06-20 00:00:00

abstract：OBJECTIVE:We aimed to determine the key predictors of perinatal deaths using machine learning models compared with the logistic regression model. DESIGN:A secondary data analysis using the Kilimanjaro Christian Medical Centre (KCMC) Medical Birth Registry cohort from 2000 to 2015. We assessed the discriminative abilit...

journal_title：BMJ open

authors： Mboya IB,Mahande MJ,Mohammed M,Obure J,Mwambi HG

更新日期：2020-10-19 00:00:00

abstract：OBJECTIVES:'Horizontal inequity' in healthcare finance occurs when people with equal income contribute unequally to healthcare payments. Prior research is lacking on horizontal inequity in China. Accordingly, this study set out to examine horizontal inequity in the Chinese healthcare financing system in 2002 and 2007 t...

journal_title：BMJ open

authors： Wang Z,Zhou X,Gao Y,Chen M,Palmer AJ,Si L

更新日期：2019-01-09 00:00:00

abstract：OBJECTIVE:The COVID-19 pandemic has set unprecedented demand on the healthcare workforce around the world. The UK has been one of the most affected countries in Europe. The aim of this study was to explore the perceptions and experiences of healthcare workers (HCWs) in relation to COVID-19 and care delivery models impl...

journal_title：BMJ open

authors： Vindrola-Padros C,Andrews L,Dowrick A,Djellouli N,Fillmore H,Bautista Gonzalez E,Javadi D,Lewis-Jackson S,Manby L,Mitchinson L,Mulcahy Symmons S,Martin S,Regenold N,Robinson H,Sumray K,Singleton G,Syversen A,Vanderslott

更新日期：2020-11-05 00:00:00

abstract：INTRODUCTION:Sepsis is defined as detrimental immune response to an infection. This overwhelming reaction often abolishes a normal reconstitution of the immune cell homeostasis that in turn increases the risk for further complications. Recent studies revealed a favourable impact of ketone bodies on resolution of inflam...

journal_title：BMJ open

authors： Rahmel T,Hübner M,Koos B,Wolf A,Willemsen KM,Strauß G,Effinger D,Adamzik M,Kreth S

更新日期：2020-07-08 00:00:00

abstract：OBJECTIVE:To investigate the prevalence and factors associated with caesarean delivery in Nigeria. DESIGN:This is a secondary analysis of the nationally representative 2013 Nigeria Demographic and Health Survey (NDHS) data. We carried out frequency tabulation, χ2 test, simple logistic regression and multivariable bina...

journal_title：BMJ open

authors： Adewuyi EO,Auta A,Khanal V,Tapshak SJ,Zhao Y

更新日期：2019-06-17 00:00:00

abstract：OBJECTIVE:This study aimed to define the end-of-life (EOL) healthcare utilisation and its cost and determinants for cancer patients and to proactively inform related strategies in mainland China. DESIGN:A population-based retrospective study. SETTING AND PARTICIPANTS:Data from 894 cancer patients were collected in ur...

journal_title：BMJ open

authors： Li Z,Pan Z,Zhang L,He R,Jiang S,Xu C,Lu F,Zhang P,Li B

更新日期：2019-03-20 00:00:00

abstract：OBJECTIVES:To determine if point-of-care (POC) glycated haemoglobin (HbA₁c) is sufficiently accurate in real-world remote settings to predict or exclude the diagnosis of diabetes based on laboratory HbA1c measurements. DESIGN:Cross-sectional study comparing POC capillary HbA₁c results with corresponding venous HbA₁c l...

journal_title：BMJ open

authors： Marley JV,Oh MS,Hadgraft N,Singleton S,Isaacs K,Atkinson D

更新日期：2015-03-12 00:00:00

abstract：OBJECTIVES:Literature on associations between female genital mutilation/cutting (FGM/C) and fistula points to a common belief that FGM/C predisposes women to developing fistula. This study explores this association using nationally representative survey data. DESIGN:A secondary statistical analysis of cross-sectional ...

journal_title：BMJ open

authors： Matanda DJ,Sripad P,Ndwiga C

更新日期：2019-07-29 00:00:00

abstract：INTRODUCTION:Occurring from ultraviolet radiation combined with impairing ozone levels, uncritical sun exposure and use of tanning beds an increasing number of people are affected by different types of skin cancer. But preventive interventions like skin cancer screening are still missing the evidence for effectiveness ...

journal_title：BMJ open

authors： Beifus K,Breitbart E,Köberlein-Neu J

更新日期：2017-09-05 00:00:00

abstract：OBJECTIVE:To report on the relative cost-effectiveness of total hip arthroplasty and resurfacing arthroplasty (replacement of articular surface of femoral head only) in patients with severe arthritis suitable for hip joint resurfacing arthroplasty. DESIGN:Cost-effectiveness analysis on an intention-to-treat basis of a...

journal_title：BMJ open

authors： Edlin R,Tubeuf S,Achten J,Parsons N,Costa M

更新日期：2012-10-12 00:00:00

abstract：OBJECTIVE:How researchers' contributions relate to author order on the byline remains unclear. We sought to identify researchers' contributions associated with author order, and to explore the existence of author profiles. DESIGN:Observational study. SETTING:Published record. PARTICIPANTS:1139 authors of 119 researc...

journal_title：BMJ open

authors： Perneger TV,Poncet A,Carpentier M,Agoritsas T,Combescure C,Gayet-Ageron A

更新日期：2017-06-24 00:00:00

abstract：OBJECTIVE:There have been calls to remove 'carcinoma' from terminology for in situ cancers such as ductal carcinoma in situ (DCIS), to reduce overdiagnosis and overtreatment. We investigated the effect of describing DCIS as 'abnormal cells' versus 'pre-invasive breast cancer cells' on women's concern and treatment pref...

journal_title：BMJ open

authors： McCaffery K,Nickel B,Moynihan R,Hersch J,Teixeira-Pinto A,Irwig L,Barratt A

更新日期：2015-11-02 00:00:00

abstract：OBJECTIVE:In recent years, quality of life (QoL) in multiple sclerosis (MS) has been gaining considerable importance in clinical research and practice. Against this backdrop, this systematic review aimed to provide a broad overview of clinical, sociodemographic and psychosocial risk and protective factors for QoL in ad...

journal_title：BMJ open

authors： Gil-González I,Martín-Rodríguez A,Conrad R,Pérez-San-Gregorio MÁ

更新日期：2020-11-30 00:00:00

abstract：INTRODUCTION:A healthcare-associated infection (HAI) data point prevalence study (PPS) conducted in 1984 in Australian hospitals estimated the prevalence of HAI to be 6.3%. Since this time, there have been no further national estimates undertaken. In the absence of a coordinated national surveillance programme or regul...

journal_title：BMJ open

authors： Russo PL,Stewardson A,Cheng AC,Bucknall T,Marimuthu K,Mitchell BG

更新日期：2018-11-08 00:00:00

abstract：OBJECTIVES:Defects in the human thyroid peroxidase (TPO) gene are reported to be one of the causes of congenital hypothyroidism (CH) due to dyshormonogenesis. The aim of this study was to examine the TPO mutation spectrum and prevalence among patients with CH in the Guangxi Zhuang Autonomous Region of China and to defi...

journal_title：BMJ open

authors： Fu C,Xie B,Zhang S,Wang J,Luo S,Zheng H,Su J,Hu X,Chen R,Fan X,Luo J,Gu X,Chen S

更新日期：2016-05-12 00:00:00

abstract：INTRODUCTION:Trigeminal neuralgia (TN) affects 4 to 28.9/100 000 people worldwide, and antiepileptic drugs such as carbamazepine and oxcarbazepine are the firstline treatment options. However, the efficacy and safety of other antiepileptic drugs remain unclear due to insufficient direct comparisons. OBJECTIVE:To compa...

journal_title：BMJ open

authors： Qin Z,Xie S,Mao Z,Liu Y,Wu J,Furukawa TA,Kwong JSW,Tian J,Liu Z

更新日期：2018-01-21 00:00:00

abstract：OBJECTIVES:This study examines the use of expedited approval pathways by Health Canada over the period 1995 to 2016 inclusive and the relationship between the use of these pathways and the therapeutic gain offered by new products. DESIGN:Cross-sectional study. DATA SOURCES:Therapeutic Products Directorate, Biologics ...

journal_title：BMJ open

authors： Lexchin J

更新日期：2018-08-30 00:00:00