Reasons for non-participation in the Northern Ireland Bowel Cancer Screening Programme: a qualitative study.

abstract：OBJECTIVES:Physiological metabolic adaptations occur in the pregnant woman. These may persist postpartum and thereby contribute to an unfavourable cardiovascular disease (CVD) risk profile in parous women. The aim of the current study is to assess time-dependent changes of cardiometabolic health in parous women compare...

journal_title：BMJ open

authors： Zoet GA,Paauw ND,Groenhof K,Franx A,Gansevoort RT,Groen H,Van Rijn B,Lely T

更新日期：2019-05-05 00:00:00

abstract：OBJECTIVE:This study aimed to investigate the association between the use of isotretinoin and the risk of depression in patients with acne. DESIGN:This was a meta-analysis in which the standardised mean difference (SMD) and the relative risk (RR) were used for data synthesis employing the random-effects model. SETTIN...

journal_title：BMJ open

authors： Li C,Chen J,Wang W,Ai M,Zhang Q,Kuang L

更新日期：2019-01-21 00:00:00

abstract：OBJECTIVE:In this study, we aimed to determine the performance characteristics of toluidine red unheated serum test on cerebrospinal fluids (CSF-TRUST) as compared to venereal disease research laboratory test on cerebrospinal fluids (CSF-VDRL) for laboratory the diagnosis of neurosyphilis. DESIGN:A cross-sectional stu...

journal_title：BMJ open

authors： Gu W,Yang Y,Wu L,Yang S,Ng LK

更新日期：2013-02-21 00:00:00

abstract：BACKGROUND:The last two decades have seen an increase in literature reporting an increase in knowledge and use of contraceptives among individuals and couples in Kenya, as in the rest of Africa, but there is a dearth of information regarding knowledge about benefits of family planning (FP) in Kenya. OBJECTIVES:To asse...

journal_title：BMJ open

authors： Mutombo N,Bakibinga P,Mukiira C,Kamande E

更新日期：2014-03-18 00:00:00

abstract：INTRODUCTION:Inappropriate use of antimicrobials in hospitals contributes to antimicrobial resistance. Antimicrobial stewardship (AMS) interventions aim to improve antimicrobial prescribing, but they are often resource and personnel intensive. Computerised decision supportsystems (CDSSs) seem a promising tool to improv...

journal_title：BMJ open

authors： Catho G,De Kraker M,Waldispühl Suter B,Valotti R,Harbarth S,Kaiser L,Elzi L,Meyer R,Bernasconi E,Huttner BD

更新日期：2018-06-27 00:00:00

abstract：OBJECTIVE:Japan Coma Scale (JCS) is a grading system used to evaluate disturbed consciousness in prehospital care settings. We aimed to identify the association between the JCS levels at the scene with in-hospital mortality, as well as the discrimination ability for the outcomes. DESIGN:A retrospective cohort study ba...

journal_title：BMJ open

authors： Okada Y,Kiguchi T,Iiduka R,Ishii W,Iwami T,Koike K

更新日期：2019-07-30 00:00:00

abstract：OBJECTIVES:Liver disease is a major cause of morbidity and mortality in sub-Saharan Africa, but its prevalence, distribution and aetiology have not been well characterised. We therefore set out to examine liver function tests (LFTs) and liver fibrosis scores in a rural African population. DESIGN:We undertook a cross-s...

journal_title：BMJ open

authors： O'Hara G,Mokaya J,Hau JP,Downs LO,McNaughton AL,Karabarinde A,Asiki G,Seeley J,Matthews PC,Newton R

更新日期：2020-03-31 00:00:00

abstract：INTRODUCTION:Adequate functioning of the blood-brain barrier (BBB) is important for brain homoeostasis and normal neuronal function. Disruption of the BBB has been described in several neurological diseases. Recent reports suggest that an increased permeability of the BBB also contributes to increased seizure susceptib...

journal_title：BMJ open

authors： Haeren RH,Vink H,Staals J,van Zandvoort MA,Dings J,van Overbeeke JJ,Hoogland G,Rijkers K,Schijns OE

更新日期：2017-01-05 00:00:00

abstract：OBJECTIVE:This study aims to examine the impact of gender and expected gender roles on the career development of young female traditional Korean medicine (KM) doctors. DESIGN:We conducted semistructured interviews to examine the experiences of study subjects regarding early career choices, employment, job performance ...

journal_title：BMJ open

authors： Chun SE,Lee JH,Lee JE,Lee SMK,Leem J,Kim H

更新日期：2019-08-21 00:00:00

abstract：OBJECTIVE:The objective is to determine if suspected concussions in elite football are medically assessed according to the International Conferences on Concussion in Sport consensus statement recommendations. SETTING:Men's Union of European Football Association (UEFA) Football Championship. PARTICIPANTS:All professio...

journal_title：BMJ open

authors： Abraham KJ,Casey J,Subotic A,Tarzi C,Zhu A,Cusimano MD

更新日期：2019-05-30 00:00:00

abstract：INTRODUCTION:Despite the significant disease burden of bronchiectasis in Korea, no large-scale, representative prospective cohort studies have been conducted to evaluate the clinical characteristics of Korean patients with bronchiectasis, indicating an urgent need for cohort studies on bronchiectasis. METHODS AND ANAL...

journal_title：BMJ open

authors： Lee H,Choi H,Sim YS,Park S,Kim WJ,Yoo KH,Lee SJ,Kim TH,Yang B,Jeong I,Um SJ,Kim DK,Lee JH,Kwon BS,Cho YJ,Park HY,Lee CH,Rhee CK,Lee SH,Na JO,Jang AS,Jung JY,Ra SW,Lee JH,Kim SH,Kim C,Kim Y,Lee CY,K

更新日期：2020-01-19 00:00:00

abstract：OBJECTIVES:The microscopic evaluation of slides has been gradually moving towards all digital in recent years, leading to the possibility for computer-aided diagnosis. It is worthwhile to know the similarities between deep learning models and pathologists before we put them into practical scenarios. The simple criteria...

journal_title：BMJ open

authors： Song Z,Yu C,Zou S,Wang W,Huang Y,Ding X,Liu J,Shao L,Yuan J,Gou X,Jin W,Wang Z,Chen X,Chen H,Liu C,Xu G,Sun Z,Ku C,Zhang Y,Dong X,Wang S,Xu W,Lv N,Shi H

更新日期：2020-09-10 00:00:00

abstract：INTRODUCTION:Α substantial corpus of literature has sought to describe the information-seeking behaviour of patients with cancer. Yet, available evidence comes mainly from cross-sectional studies, which provide 'snapshots' of patients' information needs and information-seeking styles at a single time point. Only a few ...

journal_title：BMJ open

authors： Germeni E,Bianchi M,Valcarenghi D,Schulz PJ

更新日期：2015-10-06 00:00:00

abstract：INTRODUCTION:Stroke is a major health problem and transient ischaemic attack (TIA) is an important risk factor for stroke. Primary prevention of stroke and TIA will have the greatest impact on reducing the burden of these conditions. Evidence-based guidelines for stroke/TIA prevention identify individuals eligible for ...

journal_title：BMJ open

authors： Moran GM,Calvert M,Feltham MG,Marshall T

更新日期：2014-11-11 00:00:00

abstract：INTRODUCTION:Treatment fidelity is an important and often neglected component of complex behaviour change research. It is central to understanding treatment effects, especially for evaluations conducted outside of highly controlled research settings. Ensuring that promising interventions can be delivered adequately (ie...

journal_title：BMJ open

authors： Beck AK,Forbes E,Baker AL,Britton B,Oldmeadow C,Carter G

更新日期：2019-07-30 00:00:00

abstract：OBJECTIVES:To control and prevent the burdens associated with chronic kidney disease (CKD), Taiwan's National Health Insurance Administration (NHIA) launched the 'early-CKD programme' in 2011 to extend care and education to patients with CKD. This study aims to evaluate the effectiveness of the early-CKD programme in t...

journal_title：BMJ open

authors： Chen YC,Weng SF,Hsu YJ,Wei CJ,Chiu CH

更新日期：2020-12-29 00:00:00

abstract：OBJECTIVE:To assess the seroprevalence of recent/acute and past exposure to rubella virus infection and associated risk factors among pregnant women. DESIGN:A hospital-based cross-sectional study. SETTING:The study was conducted in two public hospitals in Hawassa City, Southern Ethiopia. PARTICIPANTS:A total of 422 ...

journal_title：BMJ open

authors： Tamirat B,Hussen S,Shimelis T

更新日期：2017-10-05 00:00:00

abstract：IMPORTANCE:The Use of a Multidrug Pill In Reducing cardiovascular Events (UMPIRE) trial has shown improved adherence with the use of a polypill strategy when compared with usual medications for cardiovascular disease (CVD) prevention. To advance from efficacy to impact, we need a better understanding of why and how suc...

journal_title：BMJ open

authors： Wood F,Salam A,Singh K,Day S,Jan S,Prabhakaran D,Rodgers A,Patel A,Thom S,Ward H

更新日期：2015-09-30 00:00:00

abstract：OBJECTIVE/DESIGN:It remains unclear as to the efficacy of readiness for change measurements in child and adolescent obesity intervention programmes. This observational study aimed to determine whether the caregiver's stage of change could predict outcome and adherence to treatment in an intensive intervention programme...

journal_title：BMJ open

authors： Anderson YC,Dolan GMS,Wynter LE,Treves KF,Wouldes TA,Grant CC,Cave TL,Smiley AJ,Derraik JGB,Cutfield WS,Hofman PL

更新日期：2019-03-27 00:00:00

abstract：INTRODUCTION:Periconception obesity is associated with a higher risk for adverse perinatal outcomes such as gestational diabetes mellitus, preeclampsia, large for gestational age, operative delivery and preterm birth. Lifestyle interventions during pregnancy have resulted in insufficient effects on reducing these perin...

journal_title：BMJ open

authors： Timmermans YEG,van de Kant KDG,Reijnders D,Kleijkers LMP,Dompeling E,Kramer BW,Zimmermann LJI,Steegers-Theunissen RPM,Spaanderman MEA,Vreugdenhil ACE

更新日期：2019-11-19 00:00:00

abstract：OBJECTIVES:The aim was to examine health-related quality of life (HRQoL), patient characteristics and reasons for visits to general practitioners (GPs) by frequent attenders (FAs) and a comparison group (CG) in primary care. METHODS:Patients aged 18-64 years were eligible for the study. Medical records were scrutinise...

journal_title：BMJ open

authors： Strömbom Y,Magnusson P,Karlsson J,Fredrikson M

更新日期：2019-07-30 00:00:00

abstract：INTRODUCTION:Arthroscopic surgery is a very common orthopaedic procedure. While several trials have investigated the effect of knee arthroscopy for middle-aged and older patients with meniscal tears, there is a paucity of trials comparing meniscal surgery with non-surgical treatment for younger adults. The aim of this ...

journal_title：BMJ open

authors： Skou ST,Lind M,Hölmich P,Jensen HP,Jensen C,Afzal M,Jørgensen U,Thorlund JB

更新日期：2017-08-21 00:00:00

abstract：INTRODUCTION:Haemophilia A is an X linked inherited bleeding disorder, caused by a decrease in coagulation factor VIII. Persons with haemophilia experience repeated musculoskeletal bleeding, which can lead to decreased range of motion, irreversible joint damage, low bone mineral density (BMD), and are at greater risk f...

journal_title：BMJ open

authors： Tang GH,Norris E,Petrucci J,James PD,Lee A,Poon MC,Floros G,Boma-Fischer L,Teitel J,Nisenbaum R,Sholzberg M

更新日期：2019-12-02 00:00:00

abstract：OBJECTIVE:Independent living ability is crucial for the elderly; however, its assessment performed in China employs various scales and lacks risk factors, especially behavioural and social-psychological factors, which could be improved through health education. This study aimed to assess the independent living ability ...

journal_title：BMJ open

authors： Wang B,Wu Y,Zhang T,Han J,Yu L,Sun W

更新日期：2019-10-16 00:00:00

abstract：OBJECTIVE:Insomnia is highly prevalent in prisoners and is a risk factor for poor mental well-being, depression, suicidality and aggression, all common concerns in this vulnerable population. Improving sleep management options in prison offers the potential to impact positively on a number of these common risk factors....

journal_title：BMJ open

authors： Dewa LH,Hassan L,Shaw J,Senior J

更新日期：2018-08-29 00:00:00

abstract：OBJECTIVES:Sickness absence (SA) is a widely studied integrated measure of health status. To better understand how SA behaves over time (SA trajectory) a longitudinal and individual-centred approach will allow identifying groups of individuals who share common characteristics. The aim of this study was to identify and ...

journal_title：BMJ open

authors： Ubalde-Lopez M,Hernando-Rodriguez JC,Benavides FG,Serra L

更新日期：2019-07-03 00:00:00

abstract：CONTEXT AND OBJECTIVE:Standards for clinical practice guidelines require explicit statements regarding how values and preferences influence recommendations. However, no cancer screening guideline has addressed the key question of what magnitude of benefit people require to undergo screening, given its harms and burdens...

journal_title：BMJ open

authors： Helsingen LM,Zeng L,Siemieniuk RA,Lytvyn L,Vandvik PO,Agoritsas T,Bretthauer M,Guyatt G

更新日期：2020-12-02 00:00:00

abstract：INTRODUCTION:Multifarious chronic obstructive pulmonary disease (COPD) guidelines have been published by local, national and global respiratory societies. These guidelines subsume holistic evidence based on recommendations to diagnose, treat, prevent and manage acute exacerbation with COPD. Despite the existing compreh...

journal_title：BMJ open

authors： Issac H,Moloney C,Taylor M,Lea J

更新日期：2020-07-20 00:00:00

abstract：INTRODUCTION:Generally, complete resection with cancer cell negative (R0) margin has been accepted as the most effective treatment of gastric cancer and positive resection (R1/R2) margin has been associated with decreased survival to varied degrees. However, the independent impact of microscopical positive (R1) margin ...

journal_title：BMJ open

authors： Jiang Z,Cai Z,Yin Y,Shen C,Huang J,Yin Y,Zhang B

更新日期：2020-11-04 00:00:00

abstract：INTRODUCTION:Despite the frequent use of therapies in acute bronchitis, the evidence of their benefit is lacking, since only a few clinical trials have been published, with low sample sizes, poor methodological quality and mainly in children. The objective of this study is to compare the effectiveness of three symptoma...

journal_title：BMJ open

authors： Cots JM,Moragas A,García-Sangenís A,Morros R,Gomez-Lumbreras A,Ouchi D,Monfà R,Pera H,Pujol J,Bayona C,de la Poza-Abad M,Llor C

更新日期：2019-05-16 00:00:00