Maternal age and the risk of adverse pregnancy outcomes: a retrospective cohort study.

Abstract:

BACKGROUND:The increased potential for negative pregnancy outcomes in both extremes of reproductive age is a well-debated argument. The aim of this study was to analyze the prevalence and the outcome of pregnancies conceived at extreme maternal ages. METHODS:This retrospective study considered all single consecutive pregnancies delivered in a tertiary referral center between 2001 and 2014. Patients were categorized into 4 groups according to maternal age at delivery (< 17 years; 18-28 years; 29-39 years; > 40 years). The following outcomes were considered (amongst others): pregnancy-related hypertensive disorders (PRHDs), neonatal resuscitation (NR), neonatal intensive care unit (NICU) admission, periventricular leucomalacia (PVL), and grade 3 and 4 intraventicular hemorrhage (IVH). RESULTS:During the considered period 22,933 single pregnancies gave birth in our unit. We observed 71 women aged < 17 years, and 1552 aged > 40 years. In each year throughout the study period, there was a significant increment in maternal age of 0.041 years (95% CI 0.024-0.058) every new year. Multivariate analysis concluded out that maternal age over 40 years was an independent risk factor for preterm delivery (OR 1.36 95% CI 1.16-1.61, p < 0.05, PRHDs (OR 2.36 95% CI 1.86-3.00, p < 0.05), GDM (OR 1.71 95% CI 1.37-2.12, p < 0.05) cesarean section (OR 1.99 95% CI 1.78-2.23, p < 0.05), abnormal fetal presentation (OR 1.29 95% CI 1.03-1.61, p < 0.05), and fetal PVL (OR 3.32 95% CI 1.17-9.44, p < 0.05). We also observed that maternal age under 17 years or over 40 years was an independent risk factor for grade 3 or 4 neonatal IVH (OR 2.97 95% CI 1.24-7.14, p < 0.05). CONCLUSIONS:These findings confirm a negative impact of extreme maternal ages on pregnancy. These results should be carefully taken into account by maternal care providers in order to inform women adequately, supporting them in understanding potential risks associated with their procreation choices, and to improve clinical surveillance.

authors

Londero AP,Rossetti E,Pittini C,Cagnacci A,Driul L

doi

10.1186/s12884-019-2400-x

subject

Has Abstract

pub_date

2019-07-23 00:00:00

pages

261

issue

1

issn

1471-2393

pii

10.1186/s12884-019-2400-x

journal_volume

19

pub_type

杂志文章
  • The social, psychological, emotional morbidity and adjustment techniques for women with anal incontinence following Obstetric Anal Sphincter Injury: use of a word picture to identify a hidden syndrome.

    abstract:BACKGROUND:To identify the emotional, social and psychological consequences and recovery process of anal incontinence (AI) following obstetric anal sphincter injuries (OASIS) and explore if this can be identified as a recognisable syndrome with visual representation. METHODS:A qualitative approach was adopted for this...

    journal_title:BMC pregnancy and childbirth

    pub_type: 杂志文章

    doi:10.1186/s12884-016-1065-y

    authors: Keighley MR,Perston Y,Bradshaw E,Hayes J,Keighley DM,Webb S

    更新日期:2016-09-21 00:00:00

  • Geophagy practices and the content of chemical elements in the soil eaten by pregnant women in artisanal and small scale gold mining communities in Tanzania.

    abstract:BACKGROUND:Geophagy, a form of pica, is the deliberate consumption of soil and is relatively common across Sub-Saharan Africa. In Tanzania, pregnant women commonly eat soil sticks sold in the market (pemba), soil from walls of houses, termite mounds, and ground soil (kichuguu). The present study examined geophagy pract...

    journal_title:BMC pregnancy and childbirth

    pub_type: 杂志文章

    doi:10.1186/1471-2393-14-144

    authors: Nyanza EC,Joseph M,Premji SS,Thomas DS,Mannion C

    更新日期:2014-04-15 00:00:00

  • Decision-to-delivery interval of emergency cesarean section in Uganda: a retrospective cohort study.

    abstract:BACKGROUND:In many low and medium human development index countries, the rate of maternal and neonatal morbidity and mortality is high. One factor which may influence this is the decision-to-delivery interval of emergency cesarean section. We aimed to investigate the maternal risk factors, indications and decision-to-d...

    journal_title:BMC pregnancy and childbirth

    pub_type: 杂志文章

    doi:10.1186/s12884-020-03010-x

    authors: Hughes NJ,Namagembe I,Nakimuli A,Sekikubo M,Moffett A,Patient CJ,Aiken CE

    更新日期:2020-05-27 00:00:00

  • Macular choroidal thickness in highly myopic women during pregnancy and postpartum: a longitudinal study.

    abstract:BACKGROUND:High myopia, a cause of serious visual impairment, is a significant global public health concern. We investigate longitudinal changes in macular choroidal thickness (CT) during pregnancy and 6-months postpartum in women with high myopia (HM). METHODS:A prospective longitudinal study was conducted in HM-preg...

    journal_title:BMC pregnancy and childbirth

    pub_type: 杂志文章

    doi:10.1186/s12884-018-1865-3

    authors: Chen W,Li L,Zhang H,Li Y,Chen X,Zhang Y

    更新日期:2018-06-08 00:00:00

  • Prenatal diagnosis of Wolf-Hirschhorn syndrome (4p-) in association with congenital hypospadias and foot deformity.

    abstract::BACKGROUND: Wolf-Hirschhorn syndrome is caused by distal deletion of the short arm of chromosome 4 (4p-). We report a case in which intrauterine growth restriction, hypospadias and foot deformity were detected by prenatal ultrasound examination at 29 weeks of gestation. CASE PRESENTATION: A 31-year-old gravida 2 partu...

    journal_title:BMC pregnancy and childbirth

    pub_type: 杂志文章

    doi:10.1186/1471-2393-3-1

    authors: Aslan H,Karaca N,Basaran S,Ermis H,Ceylan Y

    更新日期:2003-01-24 00:00:00

  • Normal ranges for fetal electrocardiogram values for the healthy fetus of 18-24 weeks of gestation: a prospective cohort study.

    abstract:BACKGROUND:The fetal anomaly ultrasound only detects 65 to 81 % of the patients with congenital heart disease, making it the most common structural fetal anomaly of which a significant part is missed during prenatal life. Therefore, we need a reliable non-invasive diagnostic method which improves the predictive value f...

    journal_title:BMC pregnancy and childbirth

    pub_type: 杂志文章

    doi:10.1186/s12884-016-1021-x

    authors: Verdurmen KMJ,Lempersz C,Vullings R,Schroer C,Delhaas T,van Laar JOEH,Oei SG

    更新日期:2016-08-17 00:00:00

  • Understanding delayed access to antenatal care: a qualitative interview study.

    abstract:BACKGROUND:Delayed access to antenatal care ('late booking') has been linked to increased maternal and fetal mortality and morbidity. The aim of this qualitative study was to understand why some women are late to access antenatal care. METHODS:27 women presenting after 19 completed weeks gestation for their first hosp...

    journal_title:BMC pregnancy and childbirth

    pub_type: 杂志文章

    doi:10.1186/1471-2393-14-207

    authors: Haddrill R,Jones GL,Mitchell CA,Anumba DO

    更新日期:2014-06-16 00:00:00

  • Potential gains in reproductive-aged life expectancy if maternal mortality were eradicated from the Kintampo districts of Central Ghana.

    abstract:BACKGROUND:Almost 99% of pregnancy or childbirth-related complications globally is estimated to occur in developing regions. Yet, little is known about the demographic impact of maternal causes of death (COD) in low-and middle-income countries. Assuming that critical interventions were implemented such that maternal mo...

    journal_title:BMC pregnancy and childbirth

    pub_type: 杂志文章

    doi:10.1186/s12884-019-2515-0

    authors: Abubakari SW,Bawah AA,Nettey EO,Apraku EA,Zandoh C,Amenga-Etego S,Asante KP,Owusu-Agyei S,Badasu DM

    更新日期:2019-10-23 00:00:00

  • Differences in maternal characteristics and pregnancy outcomes between syphilitic women with and without partner coinfection.

    abstract:BACKGROUND:Partner infection is a significant factor in preventing mother-to-child syphilis transmission. We compared pregnancy outcomes between syphilis discordant and syphilis concordant couples. METHODS:We conducted a retrospective study among 3076 syphilis-positive women who received syphilis screening together wi...

    journal_title:BMC pregnancy and childbirth

    pub_type: 杂志文章

    doi:10.1186/s12884-019-2569-z

    authors: Zhang XH,Chen YM,Sun Y,Qiu LQ,Chen DQ

    更新日期:2019-11-27 00:00:00

  • Induction of labour versus expectant management for nulliparous women over 35 years of age: a multi-centre prospective, randomised controlled trial.

    abstract:BACKGROUND:British women are increasingly delaying childbirth. The proportion giving birth over the age of 35 rose from 12% in 1996 to 20% in 2006. Women over this age are at a higher risk of perinatal death, and antepartum stillbirth accounts for 61% of all such deaths. Women over 40 years old have a similar stillbirt...

    journal_title:BMC pregnancy and childbirth

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1186/1471-2393-12-145

    authors: Walker KF,Bugg G,Macpherson M,McCormick C,Wildsmith C,Smith G,Thornton J

    更新日期:2012-12-11 00:00:00

  • Correction to: The contribution of iron deficiency to the risk of peripartum transfusion: a retrospective case control study.

    abstract::Following publication of the original article [1], we have been notified that there is a missing conflict of interest. ...

    journal_title:BMC pregnancy and childbirth

    pub_type: 已发布勘误

    doi:10.1186/s12884-020-02932-w

    authors: VanderMeulen H,Strauss R,Lin Y,McLeod A,Barrett J,Sholzberg M,Callum J

    更新日期:2020-04-17 00:00:00

  • Implementation of a new prenatal care model to reduce office visits and increase connectivity and continuity of care: protocol for a mixed-methods study.

    abstract:BACKGROUND:Most low-risk pregnant women receive the standard model of prenatal care with frequent office visits. Research suggests that a reduced schedule of visits among low-risk women could be implemented without increasing adverse maternal or fetal outcomes, but patient satisfaction with these models varies. We aim ...

    journal_title:BMC pregnancy and childbirth

    pub_type: 杂志文章,随机对照试验

    doi:10.1186/s12884-015-0762-2

    authors: Ridgeway JL,LeBlanc A,Branda M,Harms RW,Morris MA,Nesbitt K,Gostout BS,Barkey LM,Sobolewski SM,Brodrick E,Inselman J,Baron A,Sivly A,Baker M,Finnie D,Chaudhry R,Famuyide AO

    更新日期:2015-12-02 00:00:00

  • Factors influencing access of pregnant women and their infants to their local healthcare system: a prospective, multi-centre, observational study.

    abstract:BACKGROUND:The successful implementation of maternal vaccination relies on results of clinical trials, considering the prenatal and postnatal attendance at selected healthcare institutions. This study evaluated factors influencing maternal/infant access to healthcare facilities to identify potential barriers to partici...

    journal_title:BMC pregnancy and childbirth

    pub_type: 杂志文章,多中心研究

    doi:10.1186/s12884-017-1655-3

    authors: Madhi SA,Rivera LM,Sáez-Llorens X,Menéndez C,Carrim-Ganey N,Cotton MF,Katzman D,Luttig MM,Candelario R,Baker S,Roychoudhury M

    更新日期:2018-01-15 00:00:00

  • Low level maternal smoking and infant birthweight reduction: genetic contributions of GSTT1 and GSTM1 polymorphisms.

    abstract:BACKGROUND:Genetic susceptibility to tobacco smoke might modify the effect of smoking on pregnancy outcomes. METHODS:We conducted a case-control study of 543 women who delivered singleton live births in Kaunas (Lithuania), examining the association between low-level tobacco smoke exposure (mean: 4.8 cigarettes/day) du...

    journal_title:BMC pregnancy and childbirth

    pub_type: 杂志文章

    doi:10.1186/1471-2393-12-161

    authors: Danileviciute A,Grazuleviciene R,Paulauskas A,Nadisauskiene R,Nieuwenhuijsen MJ

    更新日期:2012-12-26 00:00:00

  • A modified surgical approach to women with obstetric anal sphincter tears by separate suturing of external and internal anal sphincter. A modified approach to obstetric anal sphincter injury.

    abstract:BACKGROUND:Long-term results after obstetric anal sphincter injury (OASI) are poor. We aimed to improve the long-term outcome after OASI by lessening symptoms of anal incontinence. METHODS:In a prospective study at Malmö University Hospital, twenty-six women with at least grade 3B OASI were classified and sutured in a...

    journal_title:BMC pregnancy and childbirth

    pub_type: 临床试验,杂志文章

    doi:10.1186/1471-2393-10-51

    authors: Lindqvist PG,Jernetz M

    更新日期:2010-09-09 00:00:00

  • Societal attitude and behaviours towards women with disabilities in rural Nepal: pregnancy, childbirth and motherhood.

    abstract:BACKGROUND:This study reviews the attitudes and behaviours in rural Nepalese society towards women with disabilities, their pregnancy, childbirth and motherhood. Society often perceives people with disabilities as different from the norm, and women with disabilities are frequently considered to be doubly discriminated ...

    journal_title:BMC pregnancy and childbirth

    pub_type: 杂志文章

    doi:10.1186/s12884-019-2171-4

    authors: Devkota HR,Kett M,Groce N

    更新日期:2019-01-09 00:00:00

  • Factors associated with recruitment, surveillance participation, and retention in an observational study of pregnant women and influenza.

    abstract:BACKGROUND:This report describes the results of recruitment efforts and the subsequent participation of pregnant women in study activities in a 2010-2012 observational study focused on influenza illness and vaccination in California and Oregon, USA. METHODS:Socio-demographic and health characteristics extracted from e...

    journal_title:BMC pregnancy and childbirth

    pub_type: 杂志文章

    doi:10.1186/s12884-019-2280-0

    authors: Thompson MG,Li DK,Naleway AL,Ferber JR,Henninger ML,Shifflett P,Sokolow LZ,Odouli R,Kauffman TL,Fink RV,Bulkley J,Cragan JD,Bozeman S

    更新日期:2019-05-08 00:00:00

  • The effect of antenatal depression and antidepressant treatment on placental tissue: a protein-validated gene expression study.

    abstract:BACKGROUND:Antenatal depression affects 10-20% of pregnant women. Around 2-4% of European pregnant women use antidepressant treatment, most commonly selective serotonin reuptake inhibitors (SSRIs). Poor pregnancy outcomes, such as preterm birth and low birth weight, have been described in women with antenatal depressio...

    journal_title:BMC pregnancy and childbirth

    pub_type: 杂志文章

    doi:10.1186/s12884-019-2586-y

    authors: Edvinsson Å,Hellgren C,Kunovac Kallak T,Åkerud H,Skalkidou A,Stener-Victorin E,Fornes R,Spigset O,Lager S,Olivier J,Sundström-Poromaa I

    更新日期:2019-12-05 00:00:00

  • Risk factors for spontaneous miscarriage above 12 weeks or premature delivery in patients undergoing cervical polypectomy during pregnancy.

    abstract:BACKGROUND:It currently remains unknown whether the resection of cervical polyps during pregnancy leads to miscarriage and/or preterm birth. This study evaluated the risk of spontaneous PTB below 34 or 37 weeks and miscarriage above 12 weeks in patients undergoing cervical polypectomy during pregnancy. METHODS:This wa...

    journal_title:BMC pregnancy and childbirth

    pub_type: 杂志文章

    doi:10.1186/s12884-019-2710-z

    authors: Fukuta K,Yoneda S,Yoneda N,Shiozaki A,Nakashima A,Minamisaka T,Imura J,Saito S

    更新日期:2020-01-09 00:00:00

  • Knowledge of hypertensive disorders in pregnancy of Moroccan women in Morocco and in the Netherlands: a qualitative interview study.

    abstract:BACKGROUND:Hypertensive disorders in pregnancy (HDP) are the most common medical disorders in pregnancy and the greatest single cause of maternal mortality worldwide. Ethnicity appears to be a significant risk factor for pregnancy related mortality and for severe maternal morbidity. Most of the complications caused by ...

    journal_title:BMC pregnancy and childbirth

    pub_type: 杂志文章

    doi:10.1186/s12884-018-1980-1

    authors: Ouasmani F,Engeltjes B,Haddou Rahou B,Belayachi O,Verhoeven C

    更新日期:2018-08-22 00:00:00

  • The use of the mHealth program Smarter Pregnancy in preconception care: rationale, study design and data collection of a randomized controlled trial.

    abstract:BACKGROUND:Unhealthy nutrition and lifestyle contribute to the worldwide rising prevalence of non-communicable diseases. This also accounts for the reproductive population, in which unhealthy behavior affects fertility and pregnancy outcome. Maternal smoking, alcohol consumption and inadequate folic acid supplement use...

    journal_title:BMC pregnancy and childbirth

    pub_type: 杂志文章,多中心研究

    doi:10.1186/s12884-017-1228-5

    authors: van Dijk MR,Oostingh EC,Koster MP,Willemsen SP,Laven JS,Steegers-Theunissen RP

    更新日期:2017-01-26 00:00:00

  • "The co-authors of pregnancy": leveraging men's sense of responsibility and other factors for male involvement in antenatal services in Kinshasa, DRC.

    abstract:BACKGROUND:Despite efforts to improve male involvement (MI), few male partners typically attend antenatal care (ANC). MI in ANC and interventions to prevent mother-to-child HIV transmission have been demonstrated to be beneficial for the HIV-positive mother and her child. This study aimed to explore factors influencing...

    journal_title:BMC pregnancy and childbirth

    pub_type: 杂志文章

    doi:10.1186/s12884-017-1587-y

    authors: Gill MM,Ditekemena J,Loando A,Ilunga V,Temmerman M,Fwamba F

    更新日期:2017-12-06 00:00:00

  • Trends in newborn umbilical cord care practices in Sokoto and Bauchi States of Nigeria: the where, who, how, what and the ubiquitous role of traditional birth attendants: a lot quality assurance sampling survey.

    abstract:BACKGROUND:Neonatal infections caused by unsafe umbilical cord practices account for the majority of neonatal deaths in Nigeria. We examined the trends in umbilical cord care practices between 2012 and 2015 that coincided with the introduction of chlorhexidine digluconate 7.1% gel in Bauchi and Sokoto States. METHODS:...

    journal_title:BMC pregnancy and childbirth

    pub_type: 杂志文章

    doi:10.1186/s12884-017-1551-x

    authors: Abegunde D,Orobaton N,Beal K,Bassi A,Bamidele M,Akomolafe T,Ohanyido F,Umar-Farouk O,Danladi S

    更新日期:2017-11-09 00:00:00

  • Care quality following intrauterine death in Spanish hospitals: results from an online survey.

    abstract:BACKGROUND:The objective of the study was to evaluate practices in Spanish hospitals after intrauterine death in terms of medical/ technical care and bereavement support care. METHODS:A cross-sectional descriptive study using an online self-completion questionnaire. The population was defined as women who had experien...

    journal_title:BMC pregnancy and childbirth

    pub_type: 杂志文章

    doi:10.1186/s12884-017-1630-z

    authors: Cassidy PR

    更新日期:2018-01-10 00:00:00

  • Evaluation of the psychometric properties of the London Measure of Unplanned Pregnancy in Brazilian Portuguese.

    abstract:BACKGROUND:Estimates of unplanned pregnancy worldwide are of concern, especially in low and middle-income countries, including Brazil. Although the contraceptive prevalence rate is high in Brazil, almost half of all pregnancies are reported as unintended. The only source of nationally representative data about pregnanc...

    journal_title:BMC pregnancy and childbirth

    pub_type: 杂志文章

    doi:10.1186/s12884-016-1037-2

    authors: Borges AL,Barrett G,Dos Santos OA,Nascimento Nde C,Cavalhieri FB,Fujimori E

    更新日期:2016-08-24 00:00:00

  • Lithuania's experience in reducing caesarean sections among nulliparas: the impact of the quality improvement course.

    abstract:BACKGROUND:To evaluate the role of the quality improvement course (QIC) to reduce the caesarean section (CS) rate among nulliparas (Robson groups 1 and 2) and to find out which group of women have reduced the CS rate following attendance at the course. METHODS:The QIC was organized in 2015. For the evaluation of the C...

    journal_title:BMC pregnancy and childbirth

    pub_type: 杂志文章

    doi:10.1186/s12884-020-2806-5

    authors: Kacerauskiene J,Minkauskiene M,Mahmood T,Bartuseviciene E,Railaite DR,Bartusevicius A,Kliucinskas M,Maleckiene L,Ulevicius J,Liubiniene L,Smigelskas K,Maciuliene K,Drasutiene G,Ramasauskaite D,Nadisauskiene RJ

    更新日期:2020-03-12 00:00:00

  • Methodology for sampling women at high maternal risk in administrative data.

    abstract:BACKGROUND:In population level studies, the conventional practice of categorizing women into low and high maternal risk samples relies upon ascertaining the presence of various comorbid conditions in administrative data. Two problems with the conventional method include variability in the recommended comorbidities to c...

    journal_title:BMC pregnancy and childbirth

    pub_type: 杂志文章,多中心研究

    doi:10.1186/s12884-019-2500-7

    authors: Vanderlaan J,Dunlop A,Rochat R,Williams B,Shapiro SE

    更新日期:2019-10-21 00:00:00

  • Methods of induction of labour: a systematic review.

    abstract:BACKGROUND:Rates of labour induction are increasing. We conducted this systematic review to assess the evidence supporting use of each method of labour induction. METHODS:We listed methods of labour induction then reviewed the evidence supporting each. We searched MEDLINE and the Cochrane Library between 1980 and Nove...

    journal_title:BMC pregnancy and childbirth

    pub_type: 杂志文章,评审

    doi:10.1186/1471-2393-11-84

    authors: Mozurkewich EL,Chilimigras JL,Berman DR,Perni UC,Romero VC,King VJ,Keeton KL

    更新日期:2011-10-27 00:00:00

  • Placental vascularization alterations in hypertensive disorders complicating pregnancy (HDCP) and small for gestational age with HDCP using three-dimensional power doppler in a prospective case control study.

    abstract:BACKGROUND:Hypertensive disorders complicating pregnancy (HDCP) continues to be a leading cause of maternal and neonatal mortality and morbidity. The clinical value of placental three-dimensional power Doppler (3DPD) in assessing HDCP requires further confirmation. The research was developed to assess changes of placen...

    journal_title:BMC pregnancy and childbirth

    pub_type: 杂志文章

    doi:10.1186/s12884-015-0666-1

    authors: Yuan T,Zhang T,Han Z

    更新日期:2015-10-05 00:00:00

  • Geographical differences in perinatal health and child welfare in the Netherlands: rationale for the healthy pregnancy 4 all-2 program.

    abstract:BACKGROUND:Geographical inequalities in perinatal health and child welfare require attention. To improve the identification, and care, of mothers and young children at risk of adverse health outcomes, the HP4All-2 program was developed. The program consists of three studies, focusing on creating a continuum for risk se...

    journal_title:BMC pregnancy and childbirth

    pub_type: 杂志文章

    doi:10.1186/s12884-017-1425-2

    authors: Waelput AJM,Sijpkens MK,Lagendijk J,van Minde MRC,Raat H,Ernst-Smelt HE,de Kroon MLA,Rosman AN,Been JV,Bertens LCM,Steegers EAP

    更新日期:2017-08-01 00:00:00