Abstract:
BACKGROUND:High myopia, a cause of serious visual impairment, is a significant global public health concern. We investigate longitudinal changes in macular choroidal thickness (CT) during pregnancy and 6-months postpartum in women with high myopia (HM). METHODS:A prospective longitudinal study was conducted in HM-pregnant women during the course of pregnancy (n = 42 eyes, 42 patients) and 6 months postpartum (n = 40 eyes, 40 patients, two cases lost).Macular CT was measured via enhanced-depth imaging (EDI)-optical coherence tomography (OCT) (EDI-OCT). Intraocular pressure (IOP), axial length (AL), refractive error, mean arterial pressure (MAP), mean ocular perfusion pressure (MOPP), and body mass index (BMI) were also measured. RESULTS:Macular CTs of HM pregnant women (214.3 ± 52.3 μm) had increased significantly during the third trimester of pregnancy compared with postpartum women (192.7 ± 51.9 μm, p = 0.014). No significant differences in AL, refractive error, or MAP were found between pregnant and postpartum groups (p > 0.05 for all parameters).During pregnancy, macular CT was negatively correlated with AL (first trimester: p = 0.010; second trimester: p = 0.013; and third trimester: p = 0.008) and positively correlated with refractive error (first trimester: p = 0.038; second trimester: p = 0.024; and third trimester: p = 0.010). No correlations between macular CT and age, IOP, MOPP, MAP, or BMI were found. CONCLUSIONS:Our study revealed the presence of a significantly thicker choroid during the third trimester of pregnancy compared with 6-mo postpartum in HM women. Macular CT positively correlated with refractive error and negatively correlated with AL during pregnancy, but did not correlate with gestational age, MOPP, IOP, MAP, or BMI.
journal_name
BMC Pregnancy Childbirthjournal_title
BMC pregnancy and childbirthauthors
Chen W,Li L,Zhang H,Li Y,Chen X,Zhang Ydoi
10.1186/s12884-018-1865-3subject
Has Abstractpub_date
2018-06-08 00:00:00pages
220issue
1issn
1471-2393pii
10.1186/s12884-018-1865-3journal_volume
18pub_type
杂志文章abstract:BACKGROUND:Limited studies have examined ethnic variation in breastfeeding and complementary feeding practices in developing countries. This study investigated ethnic variation in feeding practices in mothers with children 0-23 months old in Vietnam. METHODS:We used data on 1875 women who came from the ethnic majority...
journal_title:BMC pregnancy and childbirth
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doi:10.1186/s12884-016-0995-8
更新日期:2016-08-08 00:00:00
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journal_title:BMC pregnancy and childbirth
pub_type: 杂志文章,多中心研究,随机对照试验
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journal_title:BMC pregnancy and childbirth
pub_type: 杂志文章
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journal_title:BMC pregnancy and childbirth
pub_type: 已发布勘误
doi:10.1186/s12884-020-02932-w
更新日期:2020-04-17 00:00:00
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journal_title:BMC pregnancy and childbirth
pub_type: 杂志文章
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journal_title:BMC pregnancy and childbirth
pub_type: 杂志文章,随机对照试验
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更新日期:2019-02-04 00:00:00
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更新日期:2017-06-29 00:00:00
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更新日期:2017-08-25 00:00:00
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pub_type: 杂志文章
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pub_type: 杂志文章
doi:10.1186/s12884-020-03051-2
更新日期:2020-06-15 00:00:00
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pub_type: 杂志文章
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pub_type: 杂志文章,多中心研究
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更新日期:2018-12-22 00:00:00
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pub_type: 杂志文章
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更新日期:2018-11-14 00:00:00
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journal_title:BMC pregnancy and childbirth
pub_type: 杂志文章
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更新日期:2009-12-11 00:00:00
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pub_type: 杂志文章
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更新日期:2018-06-07 00:00:00
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pub_type: 杂志文章
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pub_type: 杂志文章
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更新日期:2021-01-12 00:00:00
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journal_title:BMC pregnancy and childbirth
pub_type: 杂志文章
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更新日期:2020-11-25 00:00:00
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pub_type: 杂志文章
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更新日期:2018-10-11 00:00:00