Risk factors for spontaneous miscarriage above 12 weeks or premature delivery in patients undergoing cervical polypectomy during pregnancy.


BACKGROUND:It currently remains unknown whether the resection of cervical polyps during pregnancy leads to miscarriage and/or preterm birth. This study evaluated the risk of spontaneous PTB below 34 or 37 weeks and miscarriage above 12 weeks in patients undergoing cervical polypectomy during pregnancy. METHODS:This was a retrospective monocentric cohort study of patients undergoing cervical polypectomy for clinical indication. Seventy-three pregnant women who underwent polypectomy were selected, and risk factors associated with miscarriage above 12 weeks or premature delivery below 34 or 37 weeks were investigated. A multivariable regression looking for predictors of spontaneous miscarriage > 12 weeks and PTB < 34 or 37 weeks were performed. RESULTS:Sixteen patients (21.9%, 16/73) had spontaneous delivery at < 34 weeks or miscarriage above 12 weeks. A univariate analysis showed that bleeding before polypectomy [odds ratio (OR) 7.7, 95% confidence interval (CI) 1.6-37.3, p = 0.004], polyp width ≥ 12 mm (OR 4.0, 95% CI 1.2-13.1, p = 0.005), the proportion of decidual polyps (OR 8.1, 95% CI 1.00-65.9, p = 0.024), and polypectomy at ≤10 weeks (OR 5.2, 95% CI 1.3-20.3, p = 0.01) were significantly higher in delivery at < 34 weeks than at ≥34 weeks. A logistic regression analysis identified polyp width ≥ 12 mm (OR 11.8, 95% CI 2.8-77.5, p = 0.001), genital bleeding before polypectomy (OR 6.5, 95% CI 1.2-55.7, p = 0.025), and polypectomy at ≤10 weeks (OR 5.9, 95% CI 1.2-45.0, p = 0.028) as independent risk factors for predicting delivery at < 34 weeks. Polyp width ≥ 12 mm and bleeding before polypectomy are risk factors for PTB < 37 wks. CONCLUSIONS:Our cohort of patients undergoing polypectomy in pregnancy have high risks of miscarriage or spontaneous premature delivery. It is unclear whether these risks are given by the underlying disease, by surgical treatment or both. This study establishes clinically relevant predictors of PTB are polyp size> 12 mm, bleeding and first trimester polypectomy. PTB risks should be exposed to patients and extensively discussed with balancing against the benefits of intervention in pregnancy.


Fukuta K,Yoneda S,Yoneda N,Shiozaki A,Nakashima A,Minamisaka T,Imura J,Saito S




Has Abstract


2020-01-09 00:00:00












  • Predictors of uterine rupture in a large sample of women in Senegal and Mali: cross-sectional analysis of QUARITE trial data.

    abstract:BACKGROUND:The purpose of this study was to investigate predictors of uterine rupture in a large sample of sub-Saharan African women. Uterine rupture is rare in high-income countries, but it is more common in low-income settings where health systems are often under-resourced. However, understanding of risk factors cont...

    journal_title:BMC pregnancy and childbirth

    pub_type: 杂志文章,多中心研究,随机对照试验


    authors: Delafield R,Pirkle CM,Dumont A

    更新日期:2018-11-01 00:00:00

  • Hospitalisation for bed rest for women with a triplet pregnancy: an abandoned randomised controlled trial and meta-analysis.

    abstract::BACKGROUND: This abandoned randomised controlled trial assessed the effects of hospitalisation from 24 to 30 weeks gestation for women with a triplet pregnancy on the risk of preterm birth. METHODS: Women with a triplet pregnancy and no other condition necessitating hospital admission were approached for participation...

    journal_title:BMC pregnancy and childbirth

    pub_type: 杂志文章


    authors: Dodd JM,Crowther CA

    更新日期:2005-04-04 00:00:00

  • The effect of antenatal depression and antidepressant treatment on placental tissue: a protein-validated gene expression study.

    abstract:BACKGROUND:Antenatal depression affects 10-20% of pregnant women. Around 2-4% of European pregnant women use antidepressant treatment, most commonly selective serotonin reuptake inhibitors (SSRIs). Poor pregnancy outcomes, such as preterm birth and low birth weight, have been described in women with antenatal depressio...

    journal_title:BMC pregnancy and childbirth

    pub_type: 杂志文章


    authors: Edvinsson Å,Hellgren C,Kunovac Kallak T,Åkerud H,Skalkidou A,Stener-Victorin E,Fornes R,Spigset O,Lager S,Olivier J,Sundström-Poromaa I

    更新日期:2019-12-05 00:00:00

  • Magnitude of screening for gestational diabetes mellitus in an urban setting in Tanzania; a cross-sectional analytic study.

    abstract:BACKGROUND:Medical screening detects risk factors for disease or presence of disease in otherwise well persons in order to intervene early and reduce morbidity and mortality. During antenatal care (ANC) it is important to detect conditions that complicate pregnancy, like gestational diabetes mellitus (GDM). Despite int...

    journal_title:BMC pregnancy and childbirth

    pub_type: 杂志文章


    authors: Mukuve A,Noorani M,Sendagire I,Mgonja M

    更新日期:2020-07-23 00:00:00

  • Risk factors and comorbidities associated with magnesium deficiency in pregnant women and women with hormone-related conditions: analysis of a large real-world dataset.

    abstract:BACKGROUND:An accumulating body of literature indicates that magnesium deficiency is associated with a number of hormone-related conditions (HRC) in women, and epidemiological studies are needed to assess its prevalence and risk factors. Here, we present a secondary analysis of data pooled from four large observational...

    journal_title:BMC pregnancy and childbirth

    pub_type: 杂志文章


    authors: Orlova S,Dikke G,Pickering G,Yaltseva N,Konchits S,Starostin K,Bevz A

    更新日期:2021-01-22 00:00:00

  • Maternal venous hemodynamics in gestational hypertension and preeclampsia.

    abstract:BACKGROUND:To evaluate characteristics of venous hemodynamics, together with cardiac and arterial function, in uncomplicated pregnancies (UP), non-proteinuric gestational hypertension (GH) and preeclampsia (PE). METHODS:In this observational cross-sectional study, venous hemodynamics was assessed using a standardised ...

    journal_title:BMC pregnancy and childbirth

    pub_type: 杂志文章


    authors: Gyselaers W,Tomsin K,Staelens A,Mesens T,Oben J,Molenberghs G

    更新日期:2014-06-23 00:00:00

  • Management and outcome of pregnancies in women with red cell isoimmunization: a 15-year observational study from a tertiary care university hospital.

    abstract:BACKGROUND:The aims of this study were to determine the prevalence of the different anti-erythrocytic alloantibodies, to describe pregnancy outcomes according to a low-risk and high-risk classification for fetal anemia and to determine the factors that influence adverse perinatal outcomes. METHODS:This retrospective o...

    journal_title:BMC pregnancy and childbirth

    pub_type: 杂志文章


    authors: Sánchez-Durán MÁ,Higueras MT,Halajdian-Madrid C,Avilés García M,Bernabeu-García A,Maiz N,Nogués N,Carreras E

    更新日期:2019-10-15 00:00:00

  • A criterion audit of women's awareness of blood transfusion in pregnancy.

    abstract::BACKGROUND: In the Confidential Enquiry into Maternal Deaths (CEMD) Report, the very high risk of mortality in women who refuse blood transfusions is highlighted. The objectives were to establish current knowledge about, and views of transfusion in our pregnant population and to establish the level of compliance with ...

    journal_title:BMC pregnancy and childbirth

    pub_type: 杂志文章


    authors: Khadra M,Rigby C,Warren P,Leighton N,Johanson R

    更新日期:2002-09-25 00:00:00

  • Comparison of ferric Carboxymaltose and iron sucrose complex for treatment of iron deficiency anemia in pregnancy- randomised controlled trial.

    abstract:BACKGROUND:To evaluate the efficacy and safety of intravenous Ferric Carboxymaltose. (FCM) in comparison with intravenous Iron sucrose complex (ISC) for treatment of iron deficiency anemia in pregnancy. METHODS:A randomized clinical trial was conducted from (January 2016-August 2017). at a tertiary hospital. Pregnant ...

    journal_title:BMC pregnancy and childbirth

    pub_type: 杂志文章,随机对照试验


    authors: Jose A,Mahey R,Sharma JB,Bhatla N,Saxena R,Kalaivani M,Kriplani A

    更新日期:2019-02-04 00:00:00

  • Factors associated with childbirth self-efficacy in Australian childbearing women.

    abstract:BACKGROUND:Childbirth confidence is an important marker of women's coping abilities during labour and birth. This study investigated socio-demographic, obstetric and psychological factors affecting self-efficacy in childbearing women. METHOD:This paper presents a secondary analysis of data collected as part of the BEL...

    journal_title:BMC pregnancy and childbirth

    pub_type: 杂志文章


    authors: Schwartz L,Toohill J,Creedy DK,Baird K,Gamble J,Fenwick J

    更新日期:2015-02-13 00:00:00

  • A modified surgical approach to women with obstetric anal sphincter tears by separate suturing of external and internal anal sphincter. A modified approach to obstetric anal sphincter injury.

    abstract:BACKGROUND:Long-term results after obstetric anal sphincter injury (OASI) are poor. We aimed to improve the long-term outcome after OASI by lessening symptoms of anal incontinence. METHODS:In a prospective study at Malmö University Hospital, twenty-six women with at least grade 3B OASI were classified and sutured in a...

    journal_title:BMC pregnancy and childbirth

    pub_type: 临床试验,杂志文章


    authors: Lindqvist PG,Jernetz M

    更新日期:2010-09-09 00:00:00

  • Can a community health worker administered postnatal checklist increase health-seeking behaviors and knowledge?: evidence from a randomized trial with a private maternity facility in Kiambu County, Kenya.

    abstract:BACKGROUND:Since the 2009 WHO and UNICEF recommendation that women receive home-based postnatal care within the first three days after birth, a growing number of low-income countries have explored integrating postnatal home visit interventions into their maternal and newborn health strategies. This randomized trial eva...

    journal_title:BMC pregnancy and childbirth

    pub_type: 杂志文章,随机对照试验


    authors: McConnell M,Ettenger A,Rothschild CW,Muigai F,Cohen J

    更新日期:2016-06-04 00:00:00

  • Survey of maternal sleep practices in late pregnancy in a multi-ethnic sample in South Auckland, New Zealand.

    abstract:BACKGROUND:The Auckland Stillbirth study demonstrated a two-fold increased risk of late stillbirth for women who did not go to sleep on their left side. Two further studies have confirmed an increased risk of late stillbirth with supine sleep position. As sleep position is modifiable, we surveyed self-reported late pre...

    journal_title:BMC pregnancy and childbirth

    pub_type: 杂志文章


    authors: Cronin RS,Chelimo C,Mitchell EA,Okesene-Gafa K,Thompson JMD,Taylor RS,Hutchison BL,McCowan LME

    更新日期:2017-06-17 00:00:00

  • Comparison of the lower uterine segment in pregnant women with and without previous cesarean section in 3 T MRI.

    abstract:BACKGROUND:Prenatal risk stratification of women with previous cesarean section (CS) by ultrasound thickness measurement of the lower uterine segment (LUS) is challenging. There is a wide range of proposed cutoff values and a valuable algorithm for selection before birth is not available. Using 3 T magnetic resonance i...

    journal_title:BMC pregnancy and childbirth

    pub_type: 杂志文章


    authors: Hoffmann J,Exner M,Bremicker K,Grothoff M,Stumpp P,Stepan H

    更新日期:2019-05-08 00:00:00

  • Factors influencing the use of supervised delivery services in Garu-Tempane District, Ghana.

    abstract:BACKGROUND:There is evidence that supervised delivery has the potential to improve birth outcomes for both women and newborns. However, not all women especially in low-income settings like Ghana use supervised delivery services during childbirth. The purpose of this study was to estimate the prevalence of supervised de...

    journal_title:BMC pregnancy and childbirth

    pub_type: 杂志文章


    authors: Ganle JK,Kombet ML,Baatiema L

    更新日期:2019-04-27 00:00:00

  • A review of surrogate motherhood regulation in south American countries: pointing to a need for an international legal framework.

    abstract:BACKGROUND:Advances in science and technology coupled with globalization are changing access to and utilization of reproductive health services. This includes the transnational phenomenon of families who use surrogate mothers to reproduce, with forms of altruistic and commercial surrogacy becoming more commonplace. Sim...

    journal_title:BMC pregnancy and childbirth

    pub_type: 杂志文章,评审


    authors: Torres G,Shapiro A,Mackey TK

    更新日期:2019-01-28 00:00:00

  • Women's psychosocial outcomes following an emergency caesarean section: A systematic literature review.

    abstract:BACKGROUND:Given the sudden and unexpected nature of an emergency caesarean section (EmCS) coupled with an increased risk of psychological distress, it is particularly important to understand the psychosocial outcomes for women. The aim of this systematic literature review was to identify, collate and examine the evide...

    journal_title:BMC pregnancy and childbirth

    pub_type: 杂志文章


    authors: Benton M,Salter A,Tape N,Wilkinson C,Turnbull D

    更新日期:2019-12-30 00:00:00

  • Prevalence of postpartum depression and associated factors among postnatal care attendees in Debre Berhan, Ethiopia, 2018.

    abstract:BACKGROUND:Postpartum depression explains various groups of depressive symptoms and syndromes that can take place during the first 6 weeks following birth. The postpartum period is a critical time where both mild and severe mood disorders can occur. The familiar forms are baby blues and postpartum depression. Understan...

    journal_title:BMC pregnancy and childbirth

    pub_type: 杂志文章


    authors: Wubetu AD,Engidaw NA,Gizachew KD

    更新日期:2020-03-30 00:00:00

  • Patterns of social inequalities across pregnancy and birth outcomes: a comparison of individual and neighborhood socioeconomic measures.

    abstract:BACKGROUND:This paper identifies patterns of health inequalities (consistency and magnitude) of socioeconomic disparities for multiple maternal and child health (MCH) outcomes that represent different health care needs of mothers and infants. METHODS:Using cross-sectional national data (unweighted sample = 6,421, weig...

    journal_title:BMC pregnancy and childbirth

    pub_type: 杂志文章


    authors: Daoud N,O'Campo P,Minh A,Urquia ML,Dzakpasu S,Heaman M,Kaczorowski J,Levitt C,Smylie J,Chalmers B

    更新日期:2015-03-23 00:00:00

  • Maternal perception of decreased fetal movements from maternal and fetal perspectives, a cohort study.

    abstract:BACKGROUND:Maternal counting of fetal movement is a popular and valuable screening tool of fetal wellbeing, however it is still not known what percentage of healthy pregnant women who gave birth to healthy term newborns had experienced decreased fetal movements during gestation and what maternal and fetal factors are a...

    journal_title:BMC pregnancy and childbirth

    pub_type: 杂志文章


    authors: Sheikh M,Hantoushzadeh S,Shariat M

    更新日期:2014-08-23 00:00:00

  • A comparison of beliefs about exercise during pregnancy between Chinese and Australian pregnant women.

    abstract:BACKGROUND:Despite the well-established benefits of exercise during pregnancy, many women remain inactive. This may be related, in part, to women's beliefs about exercise in pregnancy, which are likely influenced by cultural background. Accordingly, the aim of this study was to compare attitudes, subjective norms, and ...

    journal_title:BMC pregnancy and childbirth

    pub_type: 杂志文章


    authors: Guelfi KJ,Wang C,Dimmock JA,Jackson B,Newnham JP,Yang H

    更新日期:2015-12-22 00:00:00

  • Consensus on priorities in maternal education: results of Delphi and nominal group technique approaches.

    abstract:BACKGROUND:Maternal education is wide-ranging and covers many areas from pregnancy to the immediate postpartum period and childrearing. However, for it to be effective, more resources need to be assigned to key topics. The goal of this study was to identify and prioritize the most important issues in maternal education...

    journal_title:BMC pregnancy and childbirth

    pub_type: 杂志文章


    authors: Paz-Pascual C,Artieta-Pinedo I,Grandes G,ema.Q Group.

    更新日期:2019-07-24 00:00:00

  • Delays in receiving obstetric care and poor maternal outcomes: results from a national multicentre cross-sectional study.

    abstract:BACKGROUND:The vast majority of maternal deaths in low-and middle-income countries are preventable. Delay in obtaining access to appropriate health care is a fairly common problem which can be improved. The objective of this study was to explore the association between delay in providing obstetric health care and sever...

    journal_title:BMC pregnancy and childbirth

    pub_type: 杂志文章,多中心研究


    authors: Pacagnella RC,Cecatti JG,Parpinelli MA,Sousa MH,Haddad SM,Costa ML,Souza JP,Pattinson RC,Brazilian Network for the Surveillance of Severe Maternal Morbidity study group.

    更新日期:2014-05-05 00:00:00

  • eRegistries: Electronic registries for maternal and child health.

    abstract:BACKGROUND:The Global Roadmap for Health Measurement and Accountability sees integrated systems for health information as key to obtaining seamless, sustainable, and secure information exchanges at all levels of health systems. The Global Strategy for Women's, Children's and Adolescent's Health aims to achieve a contin...

    journal_title:BMC pregnancy and childbirth

    pub_type: 杂志文章


    authors: Frøen JF,Myhre SL,Frost MJ,Chou D,Mehl G,Say L,Cheng S,Fjeldheim I,Friberg IK,French S,Jani JV,Kaye J,Lewis J,Lunde A,Mørkrid K,Nankabirwa V,Nyanchoka L,Stone H,Venkateswaran M,Wojcieszek AM,Temmerman M,Flenady

    更新日期:2016-01-19 00:00:00

  • Histologic chorioamnionitis does not modulate the oxidative stress and antioxidant status in pregnancies complicated by spontaneous preterm delivery.

    abstract:BACKGROUND:Infection induced-inflammation and other risk factors for spontaneous preterm birth (PTB) and preterm premature rupture of membranes (pPROM) may cause a redox imbalance, increasing the release of free radicals and consuming antioxidant defenses. Oxidative stress, in turn, can initiate intracellular signaling...

    journal_title:BMC pregnancy and childbirth

    pub_type: 杂志文章


    authors: Martin LF,Moço NP,de Lima MD,Polettini J,Miot HA,Corrêa CR,Menon R,da Silva MG

    更新日期:2017-11-13 00:00:00

  • Effect of different delivery modes on the short-term strength of the pelvic floor muscle in Chinese primipara.

    abstract:BACKGROUND:To investigate the effect of different delivery modes and related obstetric factors on the short-term strength of the pelvic floor muscle after delivery in Chinese primipara. METHODS:A total of 4769 healthy Chinese primiparas at postpartum 6-8 weeks were interviewed. According to the difference of delivery ...

    journal_title:BMC pregnancy and childbirth

    pub_type: 杂志文章


    authors: Zhao Y,Zou L,Xiao M,Tang W,Niu HY,Qiao FY

    更新日期:2018-07-03 00:00:00

  • Prevalence and factors associated with depressive, anxiety and stress symptoms among women with gestational diabetes mellitus in tertiary care centres in Malaysia: a cross-sectional study.

    abstract:BACKGROUND:Research on antenatal depressive, anxiety and stress symptoms among women with gestational diabetes mellitus (GDM) is lacking in Malaysia. This study aimed to determine the prevalence and factors associated with antenatal depressive, anxiety and stress symptoms among Malaysian women with GDM. METHODS:This w...

    journal_title:BMC pregnancy and childbirth

    pub_type: 杂志文章,多中心研究


    authors: Lee KW,Ching SM,Hoo FK,Ramachandran V,Chong SC,Tusimin M,Mohd Nordin N

    更新日期:2019-10-21 00:00:00

  • Exploring implicit bias in the perceived consequences of prematurity amongst health care providers in North Queensland - a constructivist grounded theory study.

    abstract:BACKGROUND:A study was done to explore the attitudes of relevant health care professionals (HCP) towards the provision of intensive care for periviable and extremely premature babies. METHODS/DESIGN:Applying a constructivist grounded theory methodology, HCP were interviewed about their attitudes towards the provision ...

    journal_title:BMC pregnancy and childbirth

    pub_type: 杂志文章


    authors: Ireland S,Ray R,Larkins S,Woodward L

    更新日期:2021-01-13 00:00:00

  • Understanding the implementation of maternity waiting homes in low- and middle-income countries: a qualitative thematic synthesis.

    abstract:BACKGROUND:Maternity waiting homes (MWHs) are accommodations located near a health facility where women can stay towards the end of pregnancy and/or after birth to enable timely access to essential childbirth care or care for complications. Although MWHs have been implemented for over four decades, different operationa...

    journal_title:BMC pregnancy and childbirth

    pub_type: 杂志文章


    authors: Penn-Kekana L,Pereira S,Hussein J,Bontogon H,Chersich M,Munjanja S,Portela A

    更新日期:2017-08-31 00:00:00

  • Is minimally invasive parathyroid surgery an option for patients with gestational primary hyperparathyroidism?

    abstract:BACKGROUND:Gestational primary hyperparathyroidism is associated with serious maternal and neonatal complications, which require prompt surgical treatment. Minimally invasive parathyroidectomy reduces pain, improves cosmesis and may achieve cure rates comparable to traditional open bilateral neck exploration. We report...

    journal_title:BMC pregnancy and childbirth

    pub_type: 杂志文章


    authors: Bendinelli C,Nebauer S,Quach T,Mcgrath S,Acharya S

    更新日期:2013-06-11 00:00:00