Abstract:
:Background Healthcare resource utilization is substantial for single-ventricle cardiac defects ( SVCD ), with effort commencing at time of fetal diagnosis through staged surgical palliation. We sought to characterize and identify variables that influence resource utilization for SVCD from fetal diagnosis through death, completed staged palliation, or cardiac transplant. Methods and Results Patients with a prenatal diagnosis of SVCD at our institution from 2004 to 2011 were screened. Patients delivered with intent to treat who received cardiac care exclusively at our institution were included. Primary end points included the total days hospitalized and the numbers of echocardiograms and cardiac catheterizations. Subanalysis was performed on survivors of completed staged palliation on the basis of Norwood operation, dominant ventricular morphology, and additional risk factors. Of 202 patients born with intent to treat, 136 patients survived to 6 months after completed staged palliation. The median number of days hospitalized per patient-year was 25.1 days, and the median numbers of echocardiograms and catheterizations per patient-year were 7.2 and 0.7, respectively. Mortality is associated with increased resource utilization. Survivors had a cumulative length of stay of 57 days and underwent a median of 21 echocardiograms and 2 catheterizations through staged palliation. Right-ventricle-dominant lesions requiring Norwood operation are associated with increased resource utilization among survivors of staged palliation. Conclusions For fetuses with SVCD , those with dominant right-ventricular morphology requiring Norwood operation demand increased resource utilization regardless of mortality. Our findings provide insight into care for SVCD , facilitate precise prenatal counseling, and provide information about the resources utilized to successfully manage SVCD .
journal_name
J Am Heart Assocjournal_title
Journal of the American Heart Associationauthors
Zielonka B,Snarr BS,Liu MY,Zhang X,Mascio CE,Fuller S,Gaynor JW,Spray TL,Rychik Jdoi
10.1161/JAHA.118.011284subject
Has Abstractpub_date
2019-06-04 00:00:00pages
e011284issue
11issn
2047-9980journal_volume
8pub_type
杂志文章abstract::Background Should all out-of-hospital cardiac arrest (OHCA) patients be directly transported to cardiac arrest centers (CACs) remains under debate. Our study evaluated the impacts of different transport time and destination hospital on the outcomes of OHCA patients. Methods and Results Data were collected from 6655 OH...
journal_title:Journal of the American Heart Association
pub_type: 杂志文章
doi:10.1161/JAHA.119.015544
更新日期:2020-06-02 00:00:00
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更新日期:2017-02-10 00:00:00
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journal_title:Journal of the American Heart Association
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doi:10.1161/JAHA.115.002323
更新日期:2015-12-16 00:00:00
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journal_title:Journal of the American Heart Association
pub_type: 杂志文章
doi:10.1161/JAHA.116.004453
更新日期:2017-05-09 00:00:00
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pub_type: 杂志文章,随机对照试验
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更新日期:2014-06-23 00:00:00
abstract::Background We aimed to determine the change in treatment strategies and times to treatment over the first 5 years of the Mission: Lifeline program. Methods and Results We assessed pre- and in-hospital care and outcomes from 2008 to 2012 for patients with ST -segment-elevation myocardial infarction at US hospitals, usi...
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pub_type: 杂志文章,多中心研究
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更新日期:2019-01-08 00:00:00
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pub_type: 杂志文章
doi:10.1161/JAHA.119.015060
更新日期:2020-05-05 00:00:00
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journal_title:Journal of the American Heart Association
pub_type: 杂志文章
doi:10.1161/JAHA.113.000304
更新日期:2013-10-21 00:00:00
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更新日期:2017-06-22 00:00:00
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更新日期:2020-06-02 00:00:00
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pub_type: 杂志文章
doi:10.1161/JAHA.116.005373
更新日期:2017-06-21 00:00:00
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pub_type: 杂志文章
doi:10.1161/JAHA.116.005254
更新日期:2017-03-20 00:00:00
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pub_type: 杂志文章,多中心研究
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更新日期:2018-06-22 00:00:00
abstract:BACKGROUND:Epidemiology of myocarditis in childhood is largely unknown. Men are known to have a higher incidence of myocarditis than women in adults aged <50 years, but whether this is true by sex in pediatric age groups is unknown. We set out to study the occurrence and potential sex differences of myocarditis in a ge...
journal_title:Journal of the American Heart Association
pub_type: 杂志文章,多中心研究
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更新日期:2017-11-18 00:00:00
abstract::Background White matter hyperintensities ( WMHs ) are commonly asymmetric between hemispheres but for unknown reasons. We investigated asymmetric WMHs associated with lacunar infarcts. Methods and Results A total of 267 consecutive patients with small first-ever supratentorial infarcts (≤20 mm) were included. None had...
journal_title:Journal of the American Heart Association
pub_type: 杂志文章
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更新日期:2018-11-20 00:00:00
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pub_type: 杂志文章,多中心研究
doi:10.1161/JAHA.118.010893
更新日期:2019-01-22 00:00:00
abstract:BACKGROUND:All clinical and biological manifestations related to postcardiac arrest (CA) syndrome are attributed to ischemia-reperfusion injury in various organs including brain and heart. Molecular hydrogen (H(2)) has potential as a novel antioxidant. This study tested the hypothesis that inhalation of H(2) gas starti...
journal_title:Journal of the American Heart Association
pub_type: 杂志文章
doi:10.1161/JAHA.112.003459
更新日期:2012-10-01 00:00:00
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pub_type: 杂志文章,多中心研究
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更新日期:2017-06-09 00:00:00
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pub_type: 杂志文章,随机对照试验
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更新日期:2019-10-15 00:00:00
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更新日期:2017-06-24 00:00:00
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更新日期:2017-08-05 00:00:00
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更新日期:2020-02-04 00:00:00
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pub_type: 杂志文章
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更新日期:2020-04-21 00:00:00
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更新日期:2017-04-24 00:00:00
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pub_type: 杂志文章
doi:10.1161/JAHA.119.012008
更新日期:2019-05-07 00:00:00
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pub_type: 杂志文章
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更新日期:2017-06-06 00:00:00
abstract:BACKGROUND:A prior randomized controlled trial of social media exposure at Circulation determined that social media did not increase 30-day page views. Whether insufficient social media intensity contributed to these results is uncertain. METHODS AND RESULTS:Original article manuscripts were randomized to social media...
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pub_type: 杂志文章,随机对照试验
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更新日期:2016-04-27 00:00:00
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pub_type: 杂志文章,随机对照试验
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更新日期:2013-05-10 00:00:00
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更新日期:2018-03-23 00:00:00
abstract::Background Recent evidence suggests that racial/ethnic differences in circulating levels of free or bioavailable 25-hydroxy vitamin D (25[ OH ]D) rather than total 25( OH )D may explain apparent racial disparities in cardiovascular disease ( CVD ). We prospectively examined black-white differences in the associations ...
journal_title:Journal of the American Heart Association
pub_type: 杂志文章
doi:10.1161/JAHA.118.011021
更新日期:2019-02-19 00:00:00