Abstract：
:Postoperative management after major lung surgery is critical. This study evaluates risk factors for predicting mandatory intensive care unit (ICU) admission immediately after major lung resection. We retrospectively reviewed patients for whom the surgeon requested an ICU bed before major lung resection surgery. Patients were classified into three groups. Univariable and multivariable logistic regression analyses were performed, and a clinical nomogram was constructed. Among 340 patients, 269, 50, and 21 were classified into the no need for ICU, mandatory ICU admission, and late-onset complication groups, respectively. Predictive postoperative diffusion capacity of the lung for carbon monoxide (47.2 (interquartile range (IQR) 43.3-65.7)% versus vs. 67.8 (57.1-79.7)%; p = 0.003, odds ratio (OR) 0.969, 95% confidence interval (CI) 0.95-0.99), intraoperative blood loss (400.00 (250.00-775.00) mL vs. 100.00 (50.00-250.00) mL; p = 0.040, OR 1.001, 95% CI 1.000-1.002), and open thoracotomy (p = 0.030, OR 2.794, 95% CI 1.11-7.07) were significant predictors for mandatory ICU admission. The risk estimation nomogram demonstrated good accuracy in estimating the risk of mandatory ICU admission (concordance index 83.53%). In order to predict the need for intensive care after major lung resection, preoperative and intraoperative factors need to be considered.
journal_name
J Clin Medjournal_title
Journal of clinical medicineauthors
Kim SH,Na S,Park SY,Lee J,Kang YS,Jung HH,Kim Jdoi
10.3390/jcm8050744subject
Has Abstractpub_date
2019-05-24 00:00:00issue
5issn
2077-0383pii
jcm8050744journal_volume
8pub_type
杂志文章abstract：:Substantial progress in recent years has dramatically increased our knowledge of the molecular basis of cancer, revealing new potential therapeutic targets and paving the way for effective personalised medicine for the treatment of many tumour types. However, pancreatic cancer has been lagging behind in this success a...
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更新日期：2019-02-21 00:00:00
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更新日期：2014-09-05 00:00:00
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更新日期：2020-03-19 00:00:00
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